DIRS.INFO The most relevant business & tech news

☆ FDA proposes ending use of decongestant found in many cold, allergy medicines
▼ + stars: | 2024-11-07 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +4 min

The Food and Drug Administration on Thursday proposed ending the use of a common ingredient found in many popular over-the-counter cold and allergy medications. The agency said an extensive review of available data determined that the ingredient, oral phenylephrine, doesn't actually relieve nasal congestion. The FDA said the proposed order is not based on safety concerns and not final yet, which means companies can still market over-the-counter drugs containing oral phenylephrine for now. Last year, CVS said it has already moved to pull certain medicines containing oral phenylephrine. The designation, typically used for older medicines, allows drugmakers to include an ingredient in over-the-counter products without the need to file an FDA application.

Persons: doesn't, Patrizia Cavazzoni, Johnson, Kenvue, Phenylephrine, Pseudoephedrine Organizations: Drug Administration, FDA, FDA's Center, Drug, Research, CVS, Procter, Gamble, Bayer, Walgreens, University of Florida, Consumer Healthcare Products Association Locations: Hawthorne , California, U.S

☆ Jordan Chiles' stripped bronze is gymnastics' biggest controversy since the 2000 Sydney Olympics disaster
▼ + stars: | 2024-08-13 | by ( Https | Media-Cldnry.S-Nbcnews.Com Image Upload Newscms Kaetlyn-Liddy-Byline-Jm.Jpg | Kaetlyn Liddy | ) www.nbcnews.com time to read: +6 min

U.S. gymnast Jordan Chiles was stripped of her floor exercise bronze medal Sunday by the International Olympic Committee after a scoring inquiry was deemed invalid. Chiles is the only gymnast in history to be stripped of an Olympic medal for reasons other than age falsification or failed drug tests. The bronze medal debacle is the sport's most high-profile controversy since the 2000 Sydney Olympic Games, the site of the biggest scandal in Olympic gymnastics history. Jordan Chiles competes during the Women's Gymnastics Floor Routine final competition at the 2024 Paris Summer Olympics, at the Bercy Arena in Paris, on Aug. 5, 2024. The U.S. women's gymnastics team, which initially finished fourth in 2000, was awarded the bronze medal in 2010 after the Chinese team was disqualified.

Persons: Jordan Chiles, Chiles, Romania's Ana Bărbosu, Svetlana Khorkina, “ I’ve, ”, Kathy Kelly, Khorkina, Dmitry Lebedev, Andreea, Răducan, Simona Amânar, Raducan, Thomas Bach, Bach, ” Bach, Dong Fangxiao, Fangxiao's, Switzerland’s Fanny Smith, Germany’s Daniela Maier Organizations: International Olympic, Sport, Sydney Olympic Games, ESPN, Bercy, Kommersant, IOC, Swiss Federal Tribunal, Jordan, Beijing Winter Locations: Sydney, Paris, Soviet, Romania, Beijing, U.S

☆ Do you have seasonal allergies? Here’s how to find out and what to do
▼ + stars: | 2024-03-27 | by ( Katia Hetter | ) edition.cnn.com time to read: +8 min

More than 1 in 4 adults and nearly 1 in 5 children have seasonal allergies, according to the US Centers for Disease Control and Prevention. Are there other substances that can cause seasonal allergies? CNN: Are there other substances that can cause seasonal allergies? These are not seasonal allergies, as they aren’t related to environmental exposures and can happen year-round. There are many online resources for reducing allergens in your home that can help to decrease the impact of seasonal allergies.

Persons: CNN —, Leana Wen, It’s, I’ve Organizations: CNN, Northern, US Centers for Disease Control, Nature Communications, George Washington University, CDC

☆ Your cold pills could be yanked off the shelf. An FDA panel just ruled some of them don't work.
▼ + stars: | 2023-09-12 | by ( Associated Press | Haley Tenore | ) www.businessinsider.com time to read: +6 min

A Food and Drug Administration panel said phenylephrine, a commonly used decongestant, doesn't work. Phenylephrine is found in dozens of over-the-counter cold medications to relieve sinus congestion. Phenylephrine versions — sometimes labeled "PE" on the packaging — make up the rest. Several other commonly purchased cold and congestion relief medications also contain phenylephrine, according to The Wall Street Journal. This time, the 16 members of the FDA panel unanimously agreed that current evidence doesn't show a benefit for the drug.

Persons: Phenylephrine, Allegra, Dayquil, Mark Dykewicz, Johnson, Jennifer Schwartzott, drugmakers Organizations: Drug Administration, Food and Drug Administration, Saint Louis University School of Medicine, FDA, Bayer, Wall Street, Allergy, University of Florida, Consumer Healthcare Products Association, Congress

The advisers also told the FDA that studying phenylephrine at higher doses was not an option because it can push blood pressure to dangerous levels. This time, the 16 members of the FDA panel unanimously agreed that current evidence doesn't show a benefit for the drug. Additionally, three larger, rigorously conducted studies published since 2016 showed no difference between phenylephrine medications and placebos for relieving congestion. Those studies were conducted by Merck and Johnson & Johnson and enrolled hundreds of patients. Like many other over-the-counter ingredients, phenylephrine was essentially grandfathered into use during a sweeping FDA review begun in the 1972.

Persons: Allegra, Dayquil, ”, Mark Dykewicz, Johnson, Paul Pisaric, “, Jennifer Schwartzott, Peter Starke, drugmakers, Theresa Michele Organizations: WASHINGTON, Food and Drug Administration, Saint Louis University School of Medicine, FDA, Bayer, Archwell Health, University of Florida, Merck, Johnson, Consumer Healthcare Products Association, Congress, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group, AP Locations: Oklahoma

☆ US FDA panel says popular decongestant used in cold medicines ineffective
▼ + stars: | 2023-09-12 | by ( ) www.reuters.com time to read: +1 min

Signage is seen outside of the Food and Drug Administration (FDA) headquarters in White Oak, Maryland, U.S., August 29, 2020. REUTERS/Andrew Kelly/File Photo Acquire Licensing RightsSept 12 (Reuters) - An outside panel of experts to the U.S. Food and Drug Administration on Tuesday refused to back the effectiveness of oral over-the-counter (OTC) medicines made with phenylephrine, an ingredient widely used in cold and cough syrups. The panel unanimously voted against the effectiveness of orally administered phenylephrine as a nasal decongestant, adding that no more trials were required to prove otherwise. The FDA usually follows the recommendations of its expert panel but is not obligated to do so. Phenylephrine was substituted for pseudoephedrine in many non-prescription cold and allergy medicines after the latter was restricted amid reports of abuse.

Persons: Andrew Kelly, Jennifer Schwartzott, Phenylephrine, Mariam Sunny, Devika Organizations: Food and Drug Administration, FDA, REUTERS, U.S . Food, Drug Administration, GSK, Thomson Locations: White Oak , Maryland, U.S, United States, Bengaluru

☆ A Decongestant in Many Cold Medicines Is Ineffective
▼ + stars: | 2023-09-12 | by ( Dani Blum | More About Dani Blum | ) www.nytimes.com time to read: +2 min

Pseudoephedrine, which is found in behind-the-counter products like Sudafed, is effective at clearing congestion, Dr. Dykewicz said; just keep in mind that it can come with side effects. After that, you run the risk of rebound congestion: when the mucosal surfaces in your nose swell, making you feel even more clogged up than before. There are some sprays that you can use for longer stretches, without the rebound risk, namely steroid sprays that contain ingredients like fluticasone (Flonase) or triamcinolone (Nasacort), which are available over-the-counter. Can I treat congestion without medication? In many cases, you can treat a stuffed-up nose by standing in a steamy shower or using a humidifier to help clear your nasal passages, Dr.

Persons: ”, Jennifer Le, Dykewicz, Allegra, Mark Aronica, Le, Andrew Lane, Johns Organizations: Skaggs School of Pharmacy, Pharmaceutical Sciences, University of California, Cleveland Clinic, Sinus Locations: San Diego

☆ A Decongestant in Cold Medicines Doesn’t Work at All, an F.D.A. Panel Says
▼ + stars: | 2023-09-12 | by ( Christina Jewett | More About Christina Jewett | ) www.nytimes.com time to read: +3 min

Every cold and flu season, millions of Americans reach for these products, some over decades. The decongestant is in at least 250 products that were worth nearly $1.8 billion in sales last year, according to an agency presentation. Among the products: Sudafed Sinus Congestion, Tylenol Cold & Flu Severe, NyQuil Severe Cold & Flu, Theraflu Severe Cold Relief, Mucinex Sinus Max and others. The ingredient has long been considered safe and effective under an old, outdated agency standard, and the F.D.A. The agency also may give the drug companies a grace period to swap ingredients in products, if required.

Persons: Leslie Hendeles, Hendeles, ”, Marcia D, Howard Organizations: Staples, Medicine Cabinet, University of Florida, Consumer Healthcare Products Association, White

☆ EMA's safety committee starts review of cold medicines
▼ + stars: | 2023-02-10 | by ( ) www.reuters.com time to read: 1 min

Feb 10 (Reuters) - A European Medicines Agency (EMA) committee said on Friday it has started a review of decongestant medicines for cold and flu that contain the ingredient pseudoephedrine following safety concerns. The EMA said the review was due to reports of conditions affecting blood vessels in the brain in some patients who took pseudoephedrine-containing medicines. Pseudoephedrine is a drug that is used alone or in combination with other medicines to treat a blocked nose due to cold, flu or allergy. Makers of pseudoephedrine-containing drugs include Reckitt Benckiser (RKT.L), McNeil Products Ltd and Organon & Co (OGN.N). Reporting by Sriparna Roy in Bengaluru; Editing by Shounak DasguptaOur Standards: The Thomson Reuters Trust Principles.

☆ Afghanistan is being overrun by crystal meth
▼ + stars: | 2021-05-07 | by ( Ali Latifi | ) www.businessinsider.com time to read: +14 min

The US is leaving behind a flourishing, violent trade in heroin and crystal meth in Afghanistan. HERAT, Afghanistan — For weeks, Afghan police had been staking out a single-family house they believed was being used as a meth lab. Afghanistan's drug trade generates an estimated $35 million a month for the Taliban and drug gangs. A mysterious grassIn 2017, rumors circulated in western Afghanistan that a mysterious form of grass had been found to contain the key ingredient in crystal meth. "So long as this war continues, the drug trade will continue to grow bigger and bigger.

Search resuls for: "Pseudoephedrine"

10 mentions found