The Alzheimer's drug LEQEMBI is seen in this undated handout image obtained by Reuters on January 20, 2023.
Eisai/Handout via REUTERS/File Photo Acquire Licensing RightsBOSTON, Oct 25 (Reuters) - An injected version of Eisai (4523.T) and Biogen's (BIIB.O) Alzheimer's drug Leqembi works as well as the current intravenous version at removing toxic brain plaques, according to an analysis presented by Eisai on Wednesday.
The Japanese drugmaker's review compared data for 72 patients with early Alzheimer's given Leqembi by subcutaneous injection to prior pivotal trial results from 898 patients who received the drug by infusion.
Blood concentration levels of the drug were 11% higher with subcutaneous Leqembi than the IV version.
Roll-out of IV Leqembi, which has an annual list price of $26,500, has been slow.
Persons:
Eisai, Leqembi, ”, Eric Reiman, Priya Singhal, Biogen, Michael Irizarry, Alzheimer's, Julie Steenhuysen, Deena Beasley, Bill Berkrot, Leslie Adler
Organizations:
Reuters, REUTERS, Rights, Banner Alzheimer's Institute, ARIA, Thomson
Locations:
Handout, Boston, Los Angeles