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☆ Structure Therapeutics surges on promising early stage obesity drug data
▼ + stars: | 2023-09-29 | by ( ) www.reuters.com time to read: +1 min

Sept 29 (Reuters) - Shares of Structure Therapeutics (GPCR.O) soared 60% on Friday after the drug developer's oral obesity treatment succeeded in a small early-stage study. The drug, GSBR-1290, belongs to the same class of treatments as Novo Nordisk's (NOVOb.CO) blockbuster weight-loss drug Wegovy and Eli Lilly's (LLY.N) diabetes drug Mounjaro. Structure has said it is focused on developing oral obesity drugs that are simpler to manufacture than the current injectables. Structure "delivered better-than-expected efficacy and tolerability" for its oral drug, said Leerink Partners Research analyst David Risinger, adding that the early data was exceptional. Structure said it plans to test GSBR-1290 in two mid-stage studies as a treatment for type 2 diabetes and obesity.

Persons: Eli Lilly's, David Risinger, Bhanvi Organizations: Therapeutics, Leerink Partners, Nasdaq, Thomson Locations: California, Bengaluru

☆ A monster rally in just 3 stocks has caused short sellers to lose $30 billion so far this year
▼ + stars: | 2023-07-07 | by ( Matthew Fox | ) www.businessinsider.com time to read: +3 min

The strong rally in stocks this year has sparked big losses for short sellers, according to S3 Partners. These are the three stocks that sparked $30 billion in losses for short sellers, according to S3. In total, short sellers have seen $122.1 billion in mark-to-market losses in the first six months of the year, and just three stocks drove a total loss of $30 billion. These are the top 10 stocks that have driven the biggest losses for short sellers so far this year, according to S3 Partners. TeslaTesla launched its insurance product in 2019 Getty ImagesTicker: TSLAShort seller losses: $13.0 billionYear-to-date performance: 126.5%

Persons: —, Ihor Dusaniwsky, Dusaniwsky, it's, Lisa Su Steve Marcus, Microsoft Justin Sullivan, Nvidia Jensen Huang, Las Vegas Rick Wilking, Tesla Tesla Organizations: S3 Partners, Service, Partners Research, Partners, Nasdaq, Reuters, Broadcom Reuters, Palo Alto, Microsoft, Apple Apple, Nvidia, CES Locations: Las Vegas

☆ Writers, Seeking Pay Change for the Streaming Era, Prepare to Strike
▼ + stars: | 2023-04-30 | by ( Brooks Barnes | ) www.nytimes.com time to read: +1 min

When the most recent Hollywood strike took place — 16 years ago — the internet had not yet transformed the television and movie businesses. The superhero boom had begun for movie studios, and DVDs generated $16 billion in annual sales. Movie studios, stung by poor ticket sales for dramas and comedies, have retreated almost entirely to franchise spectacles. It’s a streaming world now. The formulas that studios use to pay television and movie creators, setting the stage for another strike.

☆ Solid first-quarter stock performance fueled 8.7% short interest jump -S3
▼ + stars: | 2023-04-17 | by ( Stephen Culp | ) www.reuters.com time to read: +1 min

NEW YORK, April 17 (Reuters) - The solid first-quarter stock market performance helped prompt an 8.7% rise in short interest in U.S. and Canadian equities markets, according to a note from S3 Partners Research released on Friday. Short interest in U.S. and Canada markets increased by $77.9 billion, or 8.7%, to $977 billion in the first quarter of 2023, S3 Partners data showed. Technology (.SPLRCT), consumer discretionary (.SPLRCD) and industrials (.SPLRCI) reported the largest quarterly increases in short exposure, while short positions in energy (.SPNY) and utilities (.SPLRCU) fell the most, wrote Ihor Dusaniwsky, managing director of Predictive Analytics at S3. Year-to-date, tech shares have surged 19.9%, consumer discretionary has advanced 13.6% and industrials have gained 2.0%. Short interest exposure is concentrated in technology (.SPLRCT), consumer discretionary (.SPLRCD) and financials, which together account for about 47% of the total $976.84 billion in short interest at the end of the quarter, according Reuters analysis of the data.

Netflix added 2.4 million new subscribers in its most recent quarter, topping expectations that it would add 1 million. According to a Wedbush survey of Netflix users, he said, people most likely to opt into the ad-supported tier are those who would have otherwise quit the platform. Netflix has also foreshadowed a crackdown on password sharing, with plans to launch a paid family offering next year. Netflix estimates 100 million households worldwide are using shared passwords — 30 million of them in North America. On Monday, it introduced a “Profile Transfer” feature designed to let users who may be sharing a subscription opt into new a Netflix membership.

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