Uber (UBER.N) shed 5.4% after the ride-hailing company missed second-quarter revenue expectations. Among pharmaceutical heavyweights, Pfizer (PFE.N) edged lower in choppy trading after the drugmaker fell short of Wall Street expectations for quarterly revenue, hit by declining sales of its COVID-19 products. Merck (MRK.N) eased 0.8% even as it raised its full-year profit forecast after posting a smaller-than-expected second-quarter loss. U.S. second-quarter earnings are now expected to fall 5.9% from a year earlier, as per Refinitiv data on Tuesday, compared with a 7.9% decline estimated a week earlier. Arista Networks (ANET.N) jumped 20.1% as the network gear maker forecast quarterly revenue above estimates after delivering better-than-expected results.

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Persons: Brendan McDermid, Mike Olsen, Johann M Cherian, Vinay Dwivedi Organizations: New York Stock Exchange, REUTERS, Reuters, PMI, Dow, Nasdaq, Caterpillar, Pfizer, Merck, U.S, Arista Networks, Dow Jones, Cruise, JetBlue Airways, American Airlines, NYSE, Thomson Locations: New York City, U.S, Bengaluru