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Top related persons:
Sriparna Roy - 1 Maju Samuel - 1 Methotrexate - 1 cisplatin - 1 China's - 1 Senators Gary Peters - 1 Debbie Stabenow - 1 Fresenius Kabi - 1
Top related locs:
Bengaluru United States India U.S
Top related orgs:
Aclaris Therapeutics - 1 ATI - 1 Thomson - 1 . Food - 1 Drug Administration - 1 FDA - 1 National Cancer Institute - 1 Pharmaceutical - 1

Search resuls for: "Methotrexate"


3 mentions found


☆ Aclaris shares plummet on terminating development of rheumatoid arthritis drug
  + stars: | 2023-11-13 | by ( ) www.reuters.com   time to read: +1 min
Companies Aclaris Therapeutics Inc FollowNov 13 (Reuters) - Aclaris Therapeutics (ACRS.O) on Monday said it would stop development of its rheumatoid arthritis treatment after it failed in a mid-stage trial, sending its shares plunging 84% before the bell. The trial tested two doses of the drug, zunsemetinib, along with anti-rheumatic drug methotrexate compared to placebo and methotrexate in patients with moderate to severe rheumatoid arthritis who have inadequate response to methotrexate alone. There was no notable differentiation between zunsemetinib and placebo across any measures of efficacy at 12 weeks, the company said. The company will also be halting enrollment in an ongoing mid-stage trial studying the drug in psoriatic arthritis. The drug developer said it is also studying its drug ATI-1777 in patients with moderate to severe atopic dermatitis which is currently in mid-stage trial.
Persons: Sriparna Roy, Maju Samuel Organizations: Aclaris Therapeutics, ATI, Thomson Locations: Bengaluru
☆ U.S. seeks new suppliers of highly used cancer drug methotrexate in short supply
  + stars: | 2023-06-09 | by ( ) www.cnbc.com   time to read: +2 min
The U.S. Food and Drug Administration said on Friday it is seeking new suppliers to ease shortages of methotrexate, one of the most commonly used cancer drugs, building on its push to shore up two other scarce chemotherapy medicines. An FDA spokesperson told Reuters the agency is looking for temporary importation options for the drug, which has been in shortage since March. Methotrexate is an injected drug used to treat a wide variety of cancers ranging from acute lymphoblastic leukemia in children, breast cancer, lung cancer, bone cancers and certain types of head and neck cancers, according to the National Cancer Institute. Last week, the FDA said it was looking for additional temporary suppliers for two other cancer chemotherapies, cisplatin and carboplatin. According to the American Society of Health-System Pharmacists, suppliers with methotrexate injections in shortage or on back order include Accord Healthcare, Fresenius Kabi, Pfizer , Teva and Hikma Pharmaceuticals .
Persons: Methotrexate, cisplatin, China's, Senators Gary Peters, Debbie Stabenow, Fresenius Kabi Organizations: . Food, Drug Administration, FDA, Reuters, National Cancer Institute, Pharmaceutical, U.S, Senators, Intas Pharmaceuticals, Healthcare, American Society of Health, System Pharmacists, Accord Healthcare, Pfizer, Teva, Hikma Pharmaceuticals Locations: United States, India, U.S
☆ The hidden side effect of overturning Roe v. Wade
  + stars: | 2022-07-12 | by ( Adam Rogers | ) www.businessinsider.com   time to read: +14 min
Which means that, to a large extent, we won't know how the court's decision to overturn Roe v. Wade is actually the health and wellbeing of women and children. We could maybe look at all pregnancy-related emergency department visits, or look at changes in miscarriage and abortion numbers before and after. But even in the days of Roe, some states — including California — refused to provide abortion data to the CDC. Abortion data, like abortions themselves, have largely been subjected to a political debate over rights, at the expense of actual knowledge. They need numbers, they need facts, they need stories."
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