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In a rare breach of Israel’s multilayered air-defense system, a drone fired by the Houthi militia in Yemen slammed into an apartment building near the United States Embassy branch office in Tel Aviv early Friday, killing at least one person and wounding eight others. Pentagon officials expressed doubt that the drone had specifically targeted the U.S. building, an attack that analysts assessed had possibly been an attempt by the Houthis to strike anywhere they could in Tel Aviv. The Houthis, an Iranian-backed militia that has been attacking ships in the Red Sea, claimed responsibility for the strike on the city of 450,000 people. No air-raid sirens warned residents before the drone crashed into the building, causing an explosion that jolted people from their sleep, shattered windows and left shrapnel scattered on the streets. “We are investigating why we did not identify it, attack it and intercept it,” Admiral Hagari said on Friday.

Persons: Daniel Hagari, Admiral Hagari Organizations: United States Embassy, Pentagon Locations: Yemen, Tel Aviv, Iranian, Red

The Iran-backed Houthi militia claimed responsibility for a rare drone attack in central Tel Aviv that crashed into a building near the United States Embassy branch office early Friday, killing at least one person and wounding eight others. Rear Adm. Daniel Hagari, the Israeli military spokesman, told reporters that Israel’s defense systems had apparently picked up the drone but failed to register it as a threat. The Israeli military said the drone had likely flown from Yemen, where the Houthis are based, before approaching Tel Aviv from the coast. Video posted on X and verified by The New York Times shows what appears to be a unmanned aerial vehicle approaching west of Tel Aviv, followed by a blast at the location of the strike. The two sides offered differing accounts of the type of drone used in the attack.

Persons: Daniel Hagari, Admiral Hagari, Nasruddin Amer Organizations: United States Embassy, The New York Times Locations: Iran, Tel Aviv, Yemen

The Iran-backed Houthi militia claimed responsibility for a drone attack in central Tel Aviv that crashed into a building near the U.S. consulate early Friday, killing at least one person. No alarms were activated in the attack, the Israeli military said earlier in a statement. The Israeli military official said it was possible that the country’s defense systems had registered the drone but misidentified it. Ron Huldai, the mayor of Tel Aviv, said the city was on heightened alert. The man was found in his apartment and had shrapnel injuries, the Tel Aviv police said in a statement.

Persons: Yahya Sarea, Ron Huldai, ”, Zaki Heller, Roee Klein, Witnesses, Matthew Mpoke Bigg, Aaron Boxerman, Ronen Bergman Organizations: Tel, Hamas, Tel Aviv police Locations: Iran, Tel Aviv, U.S, Yemen, Israel, Red, Lebanon, Gaza

☆ Israeli Military Says It Is Investigating Explosion in Tel Aviv
▼ + stars: | 2024-07-18 | by ( Erin Mendell | More About Erin Mendell | ) www.nytimes.com time to read: 1 min

The authorities in Tel Aviv said they were responding to reports of an explosion in the central part of the city early Friday morning that injured at least two people. Zaki Heller, a spokesman for Israel’s national emergency service, also known as Magen David Adom, said in a statement that its hotline had received a report at 3:21 a.m. that an object had exploded in a building. The Tel Aviv District Police said that a large number of forces were responding. The cause of the blast was not immediately clear, but the Israeli military said in a statement that it was looking into reports that there had been “an aerial target.”The two injured people were “lightly wounded” by shrapnel and were conscious, the emergency service’s statement said.

Persons: Zaki Heller, David Adom Organizations: Tel, Tel Aviv District Police Locations: Tel Aviv

☆ Gene Therapies Could Transform Rare Diseases. Are We Holding Them Back? - The New York Times
▼ + stars: | 2024-02-19 | by ( Elizabeth Currid-Halkett | ) www.nytimes.com time to read: +1 min

On Jan. 8, 2020, as I was parking my car, I got a long-awaited phone call from one of my son’s doctors. She informed me that our 7-month-old son, Eliot, had Duchenne muscular dystrophy, a fatal neuromuscular disease. I can see my neighbor walking up her steps with groceries, a leaf falling, oblivious to the devastation below. It is caused by a genetic mutation on the X chromosome, thus the disease almost exclusively affects boys (one in 3,300). lose muscle mass and thus the ability to do basic things like run and walk.

Persons: Eliot, Joan Didion, D.M.D, Jerry Mendell Organizations: Nationwide Children’s Hospital, D.M.D Locations: Columbus , Ohio

☆ Mideast Crisis Blinken Takes Bid to Avoid Wider War to Qatar and Egypt
▼ + stars: | 2024-02-06 | by ( Zolan Kanno-Youngs | Erin Mendell | ) www.nytimes.com time to read: +5 min

At the U.N. Security Council on Monday, China’s ambassador, Zhang Jun, broadly accused the United States of using excessive force around the world and manipulating public opinion about its intentions. The Security Council has frequently been a platform for U.S. and Russia’s spats over Ukraine, Syria and, most recently, the war in Gaza. “Iran has never sought to bring its dispute with the United States into Iraq’s territory,” Mr. Iravani told the Council, reiterating Iran’s stance that it does not seek a war with the United States. Algeria, the only Arab member of the Council, has drafted a new resolution calling for a permanent cease-fire in Gaza. The attacks killed 1,200 people and led to the abduction to Gaza of 240 others, Israeli officials said.

Persons: Zhang Jun, Vladimir V, Putin, Russia’s, Vasily Nebenzya, Biden, Nebenzya, “, ” Robert Wood, Mr . Wood, ”, Saeid Iravani, Mr, Iravani, Rosemary DiCarlo Organizations: . Security, United Nations Security, Security, Pentagon, Israel Locations: United States, Russia, China, Iraq, Syria, East, U.S, Ukraine, Gaza . China, Iran, The U.S, Israel, Gaza, Jordan, Middle East, America, Red, Tehran, Algeria

☆ Russia Bombards Ukraine, Killing at Least 1: Live Updates
▼ + stars: | 2023-09-06 | by ( Andrew E. Kramer | Erin Mendell | ) www.nytimes.com time to read: +5 min

Destruction near the village of Robotyne, in the Zaporizhzhia region of Ukraine, late last month. For their part, Ukrainian military officials refrained from making any sweeping claims. Ukrainians forces enjoyed surprising successes earlier in the war by holding Kyiv, the capital, and repelling Russian forces at the end of March last year. The Ukrainian military aims to reclaim land in the south and east of the country. To reach that city, Ukrainian forces would have to fully break through the defenses around Verbove and then breach additional layers.

Persons: Oleksandr Shtupun, Daniel Berehulak, Michael Kofman, Rob Lee, Volodymyr Zelensky, Gen, Oleksandr Syrskyi, Zelensky Organizations: Ukrainian Army, Black Bird Group, The New York Times, Presidential Press Service, Russian Locations: Robotyne, Zaporizhzhia, Ukraine, Ukrainian, Verbove, Russian, Moscow, Kyiv, Dmytrivka, Azov, Melitopol, Crimea, Tokmak, Bakhmut, Donetsk

☆ Blinken, in Kyiv, Says U.S. Will Send $1 Billion More in Aid
▼ + stars: | 2023-09-06 | by ( Constant Méheut | ) www.nytimes.com time to read: +6 min

The aid will also include demining assistance to clear Russian land mines and prevent the remnants of war from causing further harm to civilians, Mr. Blinken said. It includes ammunition made with depleted uranium for Abrams tanks, which are scheduled to arrive in Ukraine this fall, Mr. Blinken said. Mr. Blinken traveled by train to Kyiv with Denmark’s prime minister, Mette Frederiksen, according to a State Department statement. He was replaced by Rustem Umerov, who has been the chairman of Ukraine’s State Property Fund. A senior State Department official told reporters traveling with Mr. Blinken that the effort was aimed at “putting global support on a long-term, sustainable path.

Persons: Antony J, Blinken, Biden, Dmytro Kuleba, Volodymyr Zelensky, ” Mr, Zelensky, ”, “, Lynsey Addario, Mr, Mette Frederiksen, Blinken’s, Oleksii, Rustem Umerov, Umerov’s, Tyler Hicks, Putin, Vladimir V, Russia, Erin Mendell, Anushka Patil Organizations: Ministry of Foreign Affairs, Kyiv, United, Pentagon, The New York Times, Ukraine’s, Department, Property Fund, 22nd Mechanized Brigade, State Department Locations: Kyiv, Ukraine, U.S, United States, matériel, Kostyantynivka, Ukrainian, ”, Russia, “, Denmark, Ukraine’s, Bakhmut, Israel

The plane that listed Mr. Prigozhin as a passenger left Moscow’s Sheremetyevo airport on Wednesday at about 6 p.m. local time, bound for St. Petersburg. The paint and a partial registration number, RA-02795, visible on the aircraft match a jet that Mr. Prigozhin is known to use. Was Mr. Prigozhin killed? American officials said they could not confirm Mr. Prigozhin had been killed in the plane crash, or why the jet went down. Emerging from jail as the Soviet Union was collapsing, Mr. Prigozhin began his post-criminal career selling hot dogs on street corners in St. Petersburg, Russia.

Persons: Yevgeny V, Russian Wagner, Prigozhin, Prighozin, Dmitri Utkin, Wagner, Vladimir V, Putin, Mr, ”, Prighozhin, Putin’s Organizations: RIA Novosti, Embraer, Russian, Kremlin, Central African Locations: Russian, Moscow, Sheremetyevo, St . Petersburg, Kuzhenkino, Tver, Western, Kremlin, Russia, South Africa, Ukraine, Soviet Union, Bakhmut, Syria, Libya, Mali, Central African Republic, Belarus

Independence Day in Ukraine commemorates the country’s 1991 break from the Soviet Union, but also increasingly serves as a rallying point for Ukrainians to assert their identity and aspirations. Ukraine declared independence on Aug. 24, 1991, a few days after communist hard-liners tried to depose the Soviet leader Mikhail Gorbachev and reverse his efforts to liberalize the Soviet Union. Celebrations of Independence Day have often featured military parades and festive crowds wearing vyshyvankas, the traditional Ukrainian embroidered shirts. But Mr. Szporluk, the historian, said that Ukrainians see Independence Day not so much as a day of remembrance as one to reassert their commitment to democracy and sovereignty. On Wednesday, Mr. Zelensky took part in a ceremony on the occasion of the Day of the National Flag, which precedes Independence Day.

Persons: —, “, ” Vitali Klitschko, ”, Roman Szporluk, Volodymyr Zelensky, Mikhail Gorbachev, Lenin, Szporluk, Mr, Zelensky Organizations: Harvard Locations: Ukraine, Kyiv, Russia, Soviet Union, Europe, Moscow, ”, Independence, Russian, Ukrainian

☆ Insight: What happens when a $2 million gene therapy is not enough
▼ + stars: | 2023-08-12 | by ( Deena Beasley | ) www.reuters.com time to read: +13 min

Their experience raises broader questions around other high-cost gene therapies coming to market, sometimes after accelerated regulatory approvals, drug pricing experts said. Gene therapies work by replacing genes – the body's blueprint for its development. The gene Zolgensma delivers instructs the body to make a protein vital for muscle control. If gene therapies do fall short, it becomes harder to justify prices that researchers have argued are already poor value. More recently, the first hemophilia gene therapy approved by the U.S. Food and Drug Administration was priced by CSL Behring at $3.5 million; 26 more gene therapies are in late-stage development, according to IQVIA.

Persons: Elizabeth Kutschke, Ben, Zolgensma, Ben Kutschke, neurologists, Sitra Tauscher, Wisniewski, Ben's, Roger Hajjar, Brigham Gene, Kutschke, Vasant Narasimhan, Stacie Dusetzina, Roche's, Biogen, Roche, Maha Radhakrishnan, Steven Pearson, It's, Sree Chaguturu, Amanda Cook, Weston, Jackson, Cook, Elizabeth, Jerry Mendell, Russell Butterfield, –, Biogen's, Mendell, UMR, Spinraza, Eric Cox, Caroline Humer, Sara Ledwith Organizations: Reuters, U.S, Novartis, IQVIA Institute, Human Data, Novartis Gene Therapies, Mass, Cell Therapy, U.S . Food, Drug Administration, CSL Behring, CSL, Nashville's Vanderbilt University School of Medicine, Clinical, Economic, CVS Health, Aetna, SMA, Nationwide Children's Hospital, University of Utah Health, Children's, UnitedHealth, Thomson Locations: Oak Park, Berwyn , Illinois, Swiss, U.S, Lebanon , Virginia, United States, Columbus , Ohio, Russia, Kazakhstan, Chicago

A concrete patio was washed into a brook behind a home after flash flooding left widespread damage to the downtown in Highland Falls, N.Y., on Monday, July 10, 2023. Ms. Dagaev looked outside. Ms. Dagaev was unsteady on her feet on dry land. She called her friend, Laurie Tautel, the county legislator, who was just minutes away on Main Street in Highland Falls. “You’ve got to get me out of here!” Ms. Dagaev shouted.

Persons: Katharine Dagaev, Dagaev, Younger, Pat Flynn, Flynn, they’re, “ Let’s, Mr, couldn’t, Laurie Tautel, Tautel, “ You’ve, “, ”, ’ Organizations: “, Credit, Firefighters Locations: Highland Falls, N.Y, Highland, Hudson, New York, West Point

A train crash in eastern India on Friday was the country’s worst rail disaster in two decades, killing more than 230 people. The crash occurred when several cars of a train derailed and hit a second one, the train’s operator, South Eastern Railway, said in a statement. Local officials said that a third train, carrying freight, was ultimately involved, but details of this were not yet clear. One of the trains involved was a Shalimar-Chennai Coromandel Express train, according to South Eastern Railway. The Coromandel Express service has been known for connecting the biggest cities on India’s east coast at relatively high speed.

Persons: Pradeep Jena Organizations: Eastern Railway, Chennai Coromandel Express, South Eastern Railway, Express Locations: India, Balasore, Odisha, Shalimar, Chennai Coromandel, India’s

☆ A leaked voicemail revealed Joe Biden's message to his son Hunter as he struggled with addiction. Recovery groups hope it can inspire others to show empathy.
▼ + stars: | 2022-10-11 | by ( Natalie Musumeci | ) www.businessinsider.com time to read: +3 min

This week, a private 2018 voicemail from President Joe Biden to his son Hunter was leaked. The message revealed a concerned father pleading for his son to get help amid his drug addiction struggles. Recovery advocates told Insider they hope it inspires others to show empathy to those battling addiction. You gotta get some help," Biden says in the message. A voicemail like the one Biden left for his son is "infinitely" important to someone struggling with addiction, said Moses.

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