Tom Curry, who will win his 50th cap, moves to the blindside to reprise the successful back row partnership from the 2019 tournament, with Ben Earl at number eight.
Scrumhalf Ben Youngs starts his first game of the tournament to extend his caps record to 127, with captain Owen Farrell at flyhalf.
Jamie George, Bevan Rodd, Dan Cole, David Ribbans, Lewis Ludlam, Danny Care, George Ford and Ollie Lawrence are on the bench.
The teams met on the opening weekend of the tournament in Marseille, when England won 27-10 despite having Curry sent off after three minutes.
England have also won all four of the teams' pool clashes at the World Cup.
Persons:
Henry Arundell, Freddie Steward, Marcus Smith, Steve Borthwick, Ellis Genge, Will Stuart, Theo Dan, Ollie Chessum, Sam Underhill, Tom Curry, Ben Earl, Scrumhalf Ben Youngs, Owen Farrell, Jamie George, Bevan Rodd, Dan Cole, David Ribbans, Lewis Ludlam, Danny Care, George Ford, Ollie Lawrence, Borthwick, Smith, Arundell, Steward, Curry, Joe Marchant, Manu Tuilagi, Ben Youngs, Maro Itoje, Lewis Ludlum, Mitch Phillips, Christian Radnedge
Organizations:
England, Argentina, South, openside, Springboks, Twickenham, Thomson
Locations:
South Africa, flyhalf, Paris, Chile, Marseille, England