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CNN —This year’s Nobel Prize in physiology or medicine has been awarded to Victor Ambros and Gary Ruvkun for their work on the discovery of microRNA, a fundamental principle governing how gene activity is regulated. Their research revealed how genes give rise to different cells within the human body, a process known as gene regulation. The Nobel Prize committee announced the prestigious honor, seen as the pinnacle of scientific achievement, in Sweden on Monday. Ruvkun conducted his research at Massachusetts General Hospital, and is a professor of genetics at Harvard Medical School. Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the Nobel Prize in medicine winners on Monday.
Persons: Victor Ambros, Gary Ruvkun, Ambros, , , Ruvkun, General Thomas Perlmann, Gary Ruvkum, Jonathan Nackstrand, , Olle Kämpe, David Pendlebury, ” Pendlebury, Katalin Karikó, Drew Weissman Organizations: CNN, University of Massachusetts Medical School, Harvard University, Massachusetts General Hospital, Harvard Medical School, Getty, Clarivate’s Institute for Scientific Locations: Sweden, Massachusetts, AFP, Covid
“Science postdocs perform the science,” Donna Ginther, an economist who studies the science labor market at the University of Kansas, told CNN. Biomedical companies take scientific contributions and, over time, aggregate them into a commercial product. Building on the discovery of mRNA in the 1960’s, the technology behind an mRNA vaccine for humans was in development for decades before the Covid-19 vaccine was first administered in 2020. By using that technology to develop their mRNA vaccines for Covid-19, pharmaceutical companies like Pfizer and Moderna made a windfall in profits. “That’s how they make money is through commercialization: they have a product, which they then patent and sell.”Why are scientists leaving academic labs?
Persons: postdocs, Donna Ginther, “ They’re, Michael Ciaglo, , , Nobel, Dr, Katalin Kariko, ” Ginther, they’re, Ginther Organizations: New, New York CNN —, National Institutes of Health, NIH, National Science Foundation, University of Kansas, CNN, , Pfizer, Moderna, Wired Magazine, NSF, World Health Organization Locations: New York, United States, Denver , Colorado, Europe, Alzheimer’s
The 2023 Nobel Prize award ceremony will be held on Dec. 10, the anniversary of the death of Alfred Nobel. Kariko, from Hungary, and her U.S. colleague Weissman, whose pioneering work paved the way for mRNA COVID-19 vaccines, were announced as the Nobel Prize winners on Oct. 2. “Won the Nobel science prize for the mRNA jab yet they wore a mask to collect their award for their vaccine??!!? The photographs of the pair holding the Japan Prize were taken when the COVID-19 pandemic was still active, in April 2022. Photos show Katalin Kariko and Drew Weissman with the Japan Prize in April 2022, not the Nobel Prize in Physiology or Medicine in October 2023.
Persons: Katalin Kariko, Drew Weissman, Alfred Nobel, Weissman, , , Kariko, Read Organizations: Facebook, Japan, World Health Organization, Reuters Pictures, Reuters, Thomson Locations: Hungary, Tokyo, Japan
A Nobel for Advancing mRNA
  + stars: | 2023-10-11 | by ( The Editorial Board | ) www.wsj.com   time to read: 1 min
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Persons: Dow Jones, weissman
On Monday, Katalin Karikó won the Nobel Prize in Physiology and Medicine. Her research with Drew Weissman, with whom she shares the prize, laid the foundation for the Covid-19 vaccines developed by BioNTech-Pfizer and Moderna. During her time at the University of Pennsylvania she had trouble securing grant funding and bounced from lab to lab. "When I was doing the research I could see the promise," she tells CNBC Make It. She holds an undergraduate and masters degree from the University of Pennsylvania and an MBA from the University of California, Los Angeles.
Persons: Katalin Karikó, Drew Weissman, Susan Francia Organizations: Medicine, BioNTech, Pfizer, Moderna, Karikó's, University of Pennsylvania, CNBC, University of California Locations: Los Angeles
And for scientists, preserved footprints can lead to unexpected journeys into the past that rewrite history. National Park ServiceWhen the discovery of 61 fossilized human footprints found in New Mexico’s White Sands National Park was first announced in 2021, the ancient find changed the timeline of early humans living in the Americas. That’s why the footprints represent such a crucial missing chapter in human history. Across the universePlanetlike objects were spotted in a new image of the Orion Nebula taken by the James Webb Space Telescope. NASA/ESA/CSAAstronomers used the James Webb Space Telescope to peer inside the glowing Orion Nebula and found something completely unexpected: pairs of planetlike objects.
Persons: we’ve, Trailblazers, Katalin Karikó, Drew Weissman’s, James Webb, , Samuel G, Pearson, Webb, Edward Marshall, Christopher Columbus, , Ashley Strickland, Katie Hunt Organizations: CNN, Park Service, Sands, James Webb Space Telescope, NASA, ESA, CSA, Telescope, European Space Agency, Comedy, CNN Space, Science Locations: New, Americas, North America, China, Redonda, Flora Redonda, Caribbean, Indonesia
On Monday, Karikó, along with her collaborator Drew Weissman, won the Nobel Prize in Physiology and Medicine. It's clear, and impressive, that Karikó didn't take those obstacles personally. Suhadolnik didn't receive the news well, she says. If you have a Ph.D. from an American Ivy League [university], that's better compared to if you have a degree from a foreign university." The type of work Karikó does, Feigl-Ding says, doesn't make splashy headlines, because groundbreaking work rarely does.
Persons: Pfizer Covid, Katalin, Drew Weissman, Karikó, didn't, Robert J, Suhadolnik, Susan, Suhadolnik didn't, Gregory Zuckerman's, I'm, wasn't, Eric Feigl, Ding, doesn't, Nobel, Albert Einstein didn't, Ding epidemiologist, Weissman Organizations: Pfizer, Moderna, CNBC, University of Pennsylvania, University of Szeged, Biological Research, Temple University, Uniformed Services University of, Health Sciences, New, Systems Institute, Harvard Medical School, American Ivy League, Universities, Systems, Harvard Medical Locations: Hungary, Philadelphia, Bethesda , Maryland, UPenn, United States, U.S, New England
OSLO (AP) — The winner of the prestigious Nobel Peace Prize is being announced Friday, chosen by a panel of experts in Norway from a list of just over 350 nominations. Unlike the other Nobel prizes that are selected and announced in Stockholm, founder Alfred Nobel decreed that the peace prize be decided and awarded in Oslo by the five-member Norwegian Nobel Committee. People who can make nominations include former Nobel Peace Prize winners, members of the committee, heads of states, members of parliaments and professors of political science, history and international law. A day earlier, the Nobel committee awarded Norwegian writer Jon Fosse the prize for literature. Hungarian-American Katalin Karikó and American Drew Weissman won the Nobel Prize in medicine on Monday.
Persons: Vladimir Putin, Nelson Mandela, Barack Obama, Mikhail Gorbachev, Aung, Kyi, Alfred Nobel, Jon Fosse, Moungi Bawendi, Louis Brus, Alexei Ekimov, Anne L’Huillier, Pierre Agostini, Ferenc Krausz, Karikó, Drew Weissman Organizations: Belarusian, United Nations, Peace, Bank of Sweden, Economic Sciences Locations: OSLO, Norway, Ukraine, Belarus, Russia, Stockholm, Oslo, Norwegian, U.S, Swedish, French, Hungarian
STOCKHOLM (AP) — The Nobel Prize in literature will be announced Thursday, with the new laureate, or laureates, joining an illustrious list of past winners that ranges from Toni Morrison to Ernest Hemingway and Jean-Paul Sartre — who turned down the prize in 1964. Ernaux was just the 17th woman among the 119 Nobel literature laureates. The literature prize has long faced criticism that it is too focused on European and North American writers, as well as too male-dominated. The Nobel Peace Prize is awarded Friday and the Nobel Memorial Prize in Economic Sciences ends the awards season on Monday. The Nobel Prizes carry a cash award of 11 million Swedish kronor ($1 million) from a bequest left by the prize’s creator, Swedish inventor Alfred Nobel.
Persons: , Toni Morrison, Ernest Hemingway, Jean, Paul Sartre —, Annie Ernaux, Ernaux, Moungi, Louis Brus, Alexei Ekimov, Karikó, Drew Weissman, Anne L’Huillier, Pierre Agostini, Ferenc Krausz, Alfred Nobel, ___ Corder Organizations: STOCKHOLM, Swedish Academy, North, MIT, Louis Brus of Columbia University, Nanocrystals Technology Inc, COVID, Economic Sciences Locations: Normandy, France, Hungarian, French, Swedish, The Hague, Netherlands
STOCKHOLM (AP) — Swedish media say the Royal Swedish Academy of Sciences may have announced the winners of this year’s Nobel Prize in chemistry prematurely. Public broadcaster SVT said the academy sent a press release by mistake early Wednesday that contained the names of the winners. The press release said the prize went to three U.S.-based scientists for the “discovery and synthesis of quantum dots,” according to SVT. On Monday, Hungarian-American Katalin Karikó and American Drew Weissman won the Nobel Prize in medicine for discoveries that enabled the creation of mRNA vaccines against COVID-19. The chemistry prize means Nobel season has reached its halfway stage.
Persons: Eva Nevelius, Heiner Linke, Anne L’Huillier, Pierre Agostini, Ferenc Krausz, Karikó, Drew Weissman, Carolyn R, Barry Sharpless, Morten Meldal Organizations: STOCKHOLM, Royal Swedish Academy of Sciences, Public, SVT, Associated Press, Academy of Sciences, ” Royal Swedish Academy of Sciences, Swedish, Dagens Nyheter, COVID, Nobel Foundation Locations: Sweden, French, Swedish, Hungarian, Danish
Only the fifth woman to win a Nobel physics prize, French-born L'Huillier works at Lund University in Sweden, while Agostini, who was also born in France, is a emeritus professor at Ohio State University in the United States. Agostini and Krausz then demonstrated how this could be used to create shorter light pulses than previously possible. These experiments all showed that attosecond pulses could be observed and measured, and could be used in new experiments. While the award for peace can take the limelight, the physics prize has also often taken centre stage with winners such as Albert Einstein and awards for science that has fundamentally changed how we see the world. Announced on consecutive weekdays in early October, the physics prize announcement will be followed by ones for chemistry, literature, peace and economics, the latter a later addition to the original line-up.
Persons: Pierre Agostini, Ferenc Krausz, Anne L'Huillier, Eva Olsson, Krausz, L'Huillier, Agostini, Emmanuel Macron, Hans Ellegren, Mats Larsson, Katalin Kariko, Drew Weissman, Alfred Nobel, Albert Einstein, Niklas Pollard, Simon Johnson, Johan Ahlander, Terje Solsvik, Elizabeth Pineau, Ayhan Uyanik, Christine Uyanik, Charlotte Van Campenhout, Michaela Cabrera, Alexandra Hudson, Rosalba O'Brien Organizations: Reuters, Max Planck, Quantum Optics, Lund University, Ohio State University, Royal Academy of Sciences, Thomson Locations: STOCKHOLM, Hungarian, Garching, Germany, French, Sweden, France, United States, Stockholm, Austria, Paris, COVID, Oslo, Krisztina, Budapest, Amsterdam
Agostini, Krausz and L'Huillier win 2023 Nobel Prize in Physics
  + stars: | 2023-10-03 | by ( ) www.cnbc.com   time to read: +1 min
Journalists wait for the announcement of the winners of the 2023 Nobel Prize in Physics at Royal Swedish Academy of Sciences in Stockholm on Oct. 3, 2023. Scientists Pierre Agostini, Ferenc Krausz and Anne L'Huillier won the 2023 Nobel Prize in Physics for "experimental methods that generate attosecond pulses of light for the study of electron dynamics in matter", the award-giving body said on Tuesday. The prize, which was raised this year to 11 million Swedish crowns (about $1 million), is awarded by the Royal Swedish Academy of Sciences. Physics is the second Nobel to be awarded this week after Hungarian scientist Katalin Kariko and U.S. colleague Drew Weissman won the medicine prize for making mRNA molecule discoveries that paved the way for COVID-19 vaccines. Announced on consecutive weekdays in early October, the physics prize announcement will be followed by ones for chemistry, literature, peace and economics, the latter a later addition to the original line-up.
Persons: Pierre Agostini, Ferenc Krausz, Anne L'Huillier, Katalin Kariko, Drew Weissman, Alfred Nobel, Albert Einstein, Alain Aspect, John Clauser, Anton Zeilinger, Einstein Organizations: Royal Swedish Academy of Sciences, Royal Swedish Academy of Sciences . Physics Locations: Stockholm, COVID
This copy is for your personal, non-commercial use only. Distribution and use of this material are governed by our Subscriber Agreement and by copyright law. For non-personal use or to order multiple copies, please contact Dow Jones Reprints at 1-800-843-0008 or visit www.djreprints.com. https://www.wsj.com/health/pharma/nobel-prize-in-physiology-or-medicine-awarded-to-duo-for-covid-vaccine-development-83fc29b4
Persons: Dow Jones
CNN —This year’s Nobel Prize in physiology or medicine has been awarded to Katalin Karikó and Drew Weissman for their work on mRNA vaccines, a crucial tool in curtailing the spread of Covid-19. The Nobel Prize committee announced the prestigious honor, seen as the pinnacle of scientific achievement, in Sweden on Monday. Rickard Sandberg, a member of the Nobel Prize in medicine committee, said, “mRNA vaccines together with other Covid-19 vaccines have been administered over 13 billion times. They sold their car, Karikó told The Guardian, and stuffed the money – an equivalent of about $1,200 – in their daughter’s teddy bear for safekeeping. Weissman told CNN that their technology is much more efficient than traditional methods of producing vaccines.
Persons: Katalin Karikó, Drew Weissman, , Karikó, Weissman, Rickard Sandberg, ” Karikó, Steffen Trumpf, BioNTech, Penn Medicine J, Larry Jameson, . Weissman, ” Jameson, Drew, , Hope, I’m Organizations: CNN, University of Pennsylvania, Pfizer, Penn Medicine, UPenn’s School of Medicine, Kati, Temple University, Guardian, Moderna Locations: Covid, Sweden, Hungarian, American, Germany, Norway, Hungary, United States, Philadelphia, UPenn
And I told her that many, many scientists work very, very hard," Kariko added. BioNTech said in June that about 1.5 billion people across the world had received its mRNA shot, co-developed with Pfizer (PFE.N). [1/11]Katalin Kariko and Drew Weissman win the 2023 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm, Sweden October 2, 2023. The medicine prize kicks off this year's Nobel awards with the remaining five to be unveiled in coming days. The prizes, first handed out in 1901, were created by Swedish dynamite inventor and wealthy businessman Alfred Nobel.
Persons: Weissman, Katalin Kariko, Drew Weissman, Kariko, BioNTech, Rickard Sandberg, Susan Francia, immunologist, , Sir Andrew Pollard, Alfred Nobel, Swede Svante Paabo, Alexander Fleming, Karl Landsteiner, Niklas Pollard, Johan Ahlander, Ludwig Burger, Terje Solsvik, Andrew Cawthorne Organizations: Medicine, Nobel, Sweden's Karolinska Institute, University of Szeged, University of Pennsylvania, Pfizer, Karolinska Institute, TT News Agency, REUTERS Acquire, Boston University, Oxford University, AstraZeneca, Moderna, Thomson Locations: STOCKHOLM, COVID, Hungary, Pennsylvania, Szeged, U.S, Stockholm, Sweden, Frankfurt, Krisztina, Budapest, Oslo
mRNA vaccine: 5 things to know
  + stars: | 2023-10-02 | by ( Katie Hunt | ) edition.cnn.com   time to read: +5 min
Here are five things to know about Karikó and Weissman’s game-changing research and mRNA vaccines. What mRNA doesMessenger RNA, or mRNA, is a form of nucleic acid that tells cells what to do based on the information contained in DNA. Messenger RNA-based vaccine technology doesn’t rely on a modified version of a virus to produce an immune response. Potential beyond fighting Covid-19The advent of mRNA vaccine technology has led to safe and strong protection against Covid-19. And mRNA technology is also being checked out as a possible alternative to gene therapy for intractable conditions such as sickle cell disease.
Persons: Katalin Karikó, Drew Weissman, Peggy Peterson, Robin Shattock, ” Shattock, , Karikó, Weissman, , Roberts, Thomas Perlmann, it’s Organizations: CNN, University of Pennsylvania, Penn Medicine, Imperial College London, Covid, Penn’s Perelman, of Medicine, Vaccine, Perelman School of Medicine, Nobel Assembly Locations: Hungary
Covid-induced Nobel Prize is on brand
  + stars: | 2023-10-02 | by ( Robert Cyran | ) www.reuters.com   time to read: +4 min
They realized that modifying lab-made mRNA, a molecule used for protein production, nearly stopped the body from mounting an inflammatory response. It takes, on average, about 25 years between publishing work and receiving the Noble Prize in medicine. There are exceptions: insulin was created in 1921, administered to children in 1922, and the inventors were given the prize in 1923. Contrast that to Ralph Steinman, awarded the prize in Medicine in 2011 for work done in 1973. Follow @rob_cyran on XCONTEXT NEWSKatalin Kariko and Drew Weissman were awarded the Nobel Prize in Medicine on Oct. 2 for their work in a paper published in 2005 in the journal Immunity on mRNA molecule modifications.
Persons: Kariko, Drew Weissman, Ralph Steinman, Germany’s, Weissman, Lauren Silva Laughlin, Aditya Sriwatsav Organizations: Reuters, University of Pennsylvania, Medicine, U.S . Defense Department, Pfizer, Moderna, Thomson Locations: Covid
Katalin Karikó,(right) PhD, is a biochemist and researcher, best known for her contributions to mRNA technology and the COVID-19 vaccines. Two scientists won the Nobel Prize in medicine on Monday for discoveries that enabled the development of mRNA vaccines against COVID-19. Paabo's father, Sune Bergstrom, won the Nobel Prize in medicine in 1982. The prizes carry a cash award of 11 million Swedish kronor ($1 million). The money comes from a bequest left by the prize's creator, Swedish inventor Alfred Nobel, who died in 1896.
Persons: Drew Weissman, Karikó, Katalin, Thomas Perlmann, Gunilla Karlsson, Svante Paabo, Paabo's, Sune Bergstrom, Alfred Nobel Organizations: COVID, Sagan's University, University of Pennsylvania, Nobel Assembly Locations: Hungary, Swedish, Oslo, Stockholm
The Nobel Prize in Medicine was awarded Monday to two scientists whose work led to the mRNA vaccines against COVID-19. As countries prepared to roll out those shots, The Associated Press took a look at how the vaccines were developed so quickly. ___How could scientists race out COVID-19 vaccines so fast without cutting corners? A head start helped -- over a decade of behind-the-scenes research that had new vaccine technology poised for a challenge just as the coronavirus erupted. Both shots — one made by Pfizer and BioNTech, the other by Moderna and the National Institutes of Health — are so-called messenger RNA, or mRNA, vaccines, a brand-new technology.
Persons: Dr, Anthony Fauci, Buddy Creech, ” Creech, Tal Zaks, , Drew Weissman, Weissman, Katalin, Philip Dormitzer, Barney Graham’s, ” Fauci, Graham, Jason McLellan, hadn't, , ” Graham, Germany’s, Pfizer’s Dormitzer, Ugur Sahin Organizations: Medicine, COVID, Associated Press, Vanderbilt University, Infectious Diseases Society of America, Pfizer, BioNTech, Moderna, National Institutes of Health, NIH, University of Pennsylvania, Penn, NIH’s Vaccine Research Center, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Department of Science Education, AP Locations: U.S, Massachusetts, BioNTech, New York, China
Loncar shared his 2023 forecast, including new drugs, Nobel Prize winners, and more globalization. Brad Loncar isn't expecting a miraculous rebound for the biotech industry in 2023. In an interview with Insider, Loncar shared 10 predictions for biotech in 2023, ranging from Nobel Prize winners and presidential runs to hot cancer targets and bankruptcy worries. 2022 was a rough year for the biotech industry, which once again underperformed the stock market. The industry runs to the next super-hot cancer target: Claudin 18.2In cancer research, drug companies are always on the hunt for the next promising target.
Şapte cercetători care au dezvoltat câteva dintre vaccinurile împotriva COVID-19 au fost recompensaţi miercuri cu premiul Prinţesa de Asturias pentru Cercetare Ştiinţifică şi Tehnică pe anul 2021, la care optau 48 de aspiranţi de 17 naţionalităţi, relatează EFE.Cercetătorii recompensaţi sunt biologul ungar Katalin Karikó; imunologul american Drew Weissman; medicii germani Ugur Sahin şi Ozlem Tureci; biologul canadian Derrick Rossi; vaccinologul britanic Sarah Gilbert şi biochimistul american Philip Felgner, scrie agerpres.ro Potrivit deciziei juriului prezidat de fizicianul spaniol activitatea celor şapte cercetători constituie un excelente exemplu al importanţei ştiinţei de bază pentru a ajuta la protejarea sănătăţii la scară globală.Conform membrilor juriului, cercetătorii recompensaţi anul acesta au condus, prin activitatea lor îndelungată în cercetările de bază, la aplicaţii inovatoare precum obţinerea într-un timp extraordinar de scurt, de vaccinuri eficiente pentru a lupta împotriva pandemiei de COVID-19.Decizia juriului arată totodată că dezvoltarea tehnologiei inovatoare a ARN mesager, precum şi producţia de vaccinuri bazate pe adenovirus, deschid calea plină de speranţă spre utilizarea lor în alte boli infecţioase.Anul trecut, matematicienii francezi Yves Meyer şi Emmanuel Candes, belgianca Ingrid Daubechies şi australianul Terence Tao au fost recompensaţi împreună cu acest premiu pentru contribuţiile lor revoluţionare şi importante la teoriile şi tehnicile moderne de procesare matematică a datelor şi semnalelor.Este cel de-al şaselea premiu Prinţesa de Asturias decernat miercurea acestea după premiul pentru Arte acordat artistei sârbe Marina Abramovic, pentru cariera sa de peste 50 de ani în arta performativă, premiul pentru Comunicare şi Ştiinţe Umane acordat ziaristei şi scriitoarei americane Gloria Steinem, simbol al feminismul în SUA; premiului pentru pentru Literatură cu care a fost recompensat Emmanuel Carrere, jurnalist, scriitor, scenarist, critic şi regizor francez şi premiului pentru Cooperare Internaţională, acordat pe 16 iunie organizaţiei CAMFED (Campaign for Female Education o Campana para la Escolarización Femenina) mişcare panafricană ce investeşte în educaţia tinerelor şi a fetelor.Ceremonia de înmânare a premiilor Prinţesa de Asturias va avea lor în octombrie la Oviedo, într-o gală solemnă prezidată de regii Spaniei. Premiile Prinţesa de Asturias sunt atribuite anual unor personalităţi din domenii foarte diverse: arte, cooperare internaţională, ştiinţe sociale, comunicare, sporturi, cercetare ştiinţifică şi litere.Fiecare premiu Prinţesa de Asturias constă într-o reproducere a statuetei concepute de Joan Miro - simbol reprezentativ al premiului - un cec în valoare de 50.000 de euro, o diplomă şi o insignă.
Persons: Katalin Karikó, Drew Weissman, canadian Derrick Rossi, Sarah Gilbert, american Philip Felgner, Yves Meyer, Emmanuel Candes, Ingrid Daubechies, Tao, Gloria, Emmanuel Carrere, Joan Miro Organizations: Education Locations: Asturias, canadian, american, Prinţesa, SUA, francez, Oviedo, Spaniei
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