Jeff Zients, the White House's Covid-19 response czar, speaks during a press briefing at the White House where they spoke about a pause in issuing the Johnson & Johnson Janssen Covid-19 vaccine on April 13, 2021, in Washington, DC.
Jeff Zients will serve as President Joe Biden's next chief of staff, according to media reports on Sunday.
After the midterm elections in November and an action-packed two years in the White House, Klain has told colleagues that he is ready for something different, a Washington Post report said.
Klain previously acted as Biden's chief of staff during former President Barack Obama's first term, and he's worked with Biden since he ran for president back in 1987.
A White House representative did not immediately respond to CNBC requests for comment.