Jackson-Davis went 9 of 10 from the field and was aided by wingman Miller Kopp, who made 4 of 6 from 3-point range to add 12 points for Indiana (2-0).
Bethune-Cookman (0-2) was paced by Joe French with 11 points and Marcus Garrett with 10.
North Dakota State (0-2) got 11 points from Grant Nelson and 10 from Boden Skunberg.
9 Creighton 96, North Dakota 61Ryan Kalkbrenner collected a career-high 24 points and grabbed seven rebounds to help the Bluejays coast past North Dakota in Omaha, Neb.
Tsotne Tsartsidze sank 4 of 5 shots from 3-point range and led North Dakota (1-1) with 16 points.