Roughly 15% of participants who discontinued antidepressants experienced withdrawal symptoms such as dizziness, headaches, nausea, insomnia and irritability, according to the review published Wednesday in the journal The Lancet Psychiatry.
The review is the first publication of a larger project on antidepressant withdrawal symptoms, the authors said.
The authors also discovered the medications most often linked with withdrawal symptoms were desvenlafaxine, venlafaxine, imipramine and escitalopram.
The rate of withdrawal symptoms in pharma-funded studies was about the same as trials not funded by pharmaceutical companies.
The study didn’t provide information on the duration of withdrawal symptoms, but other research suggests they can last for up to two weeks in most cases, Keedwell said.
Persons:
”, Jonathan Henssler, ” Henssler, Sameer Jauhar, Jauhar wasn’t, ” Jauhar, Christiaan Vinkers, weren’t, Tony Kendrick, “, ” Kendrick, Henssler, Jauhar, Oliver Howes, Howes wasn’t, Paul Keedwell, wasn’t, Keedwell, ” Keedwell
Organizations:
Lifeline, CNN, neurosciences, Charité — University Medicine, King’s College London, Pharmaceutical, pharma, Amsterdam University Medical Center, University of Southampton, Cleveland Clinic, Royal College of Psychiatrists
Locations:
United Kingdom, Berlin, England