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Ron DeSantis’ administration is once again advising against the mRNA vaccines: this time in the most vulnerable residents. In updated guidance for health care providers released Thursday, the Florida Health Department and state Surgeon General Joseph Ladapo questioned the safety and effectiveness of the mRNA Covid vaccines from Pfizer and Moderna, including for older adults and people with underlying health problems. Dr. Paul Offit, a vaccine expert at Children’s Hospital of Philadelphia, said the Florida surgeon general's guidance is unnecessarily alarming people about the Covid vaccines. "The mRNA vaccines are remarkably safe," he added. The CDC currently recommends everyone ages 6 months and older get an updated Covid vaccine this fall from any of the three options.

Persons: Ron DeSantis ’, Joseph Ladapo, Nature Cardiovascular Research , Paul Offit, Offit, They’re, Isaac Bogoch, ”, Boguch, Ladapo Organizations: Florida Health Department, Pfizer, Moderna, Nature Cardiovascular Research, Children’s Hospital of Philadelphia, Food and Drug Administration, United States, University of Toronto, CDC, Emergency Locations: Florida, U.S

The shots will be important, however, as the U.S. heads into the fall and winter, when cases usually rise again. Vaccine experts select the Covid strain in the spring for a vaccination campaign in the fall. Last fall, when CDC data showed a rise in hospitalizations, some doctors criticized the FDA for waiting too long to roll out the updated Covid vaccines. Has the FDA considered changing the fall vaccine rollout schedule, now early September? Link-Gelles highlighted the challenges in determining the optimal timing for administering the Covid vaccines.

Persons: Will, ”, John Moore, Akiko Iwasaki, Covid —, CDC epidemiologist Ruth Link, that’s, Isaac Bogoch, “, Ofer Levy, Levy, ” Levy, it’s, ” Weill Cornell's Moore, “ I’m, what’s, ” Moore Organizations: Weill Cornell Medical College, “, Centers for Disease Control, Food and Drug Administration, Yale University, FDA, CDC, NBC, University of Toronto, Precision, Boston Children’s Hospital Locations: U.S, hospitalizations

☆ FDA proposes simplifying the Covid vaccine schedule, making it similar to the flu shot
▼ + stars: | 2023-01-23 | by ( Https | Media-Cldnry.S-Nbcnews.Com Image Upload Newscms Berkeley-Lovelace-Jr.Jpg | Berkeley Lovelace Jr. | ) www.nbcnews.com time to read: +3 min

Food and Drug Administration advisers will meet Thursday to discuss simplifying the Covid vaccination schedule, allowing most people to get the currently available booster, regardless of how many doses they had received before that. The FDA is proposing skipping over that primary series, meaning that most unvaccinated individuals could go ahead and get the latest booster shot if they decided to get a Covid vaccine. The FDA’s proposal, experts say, would greatly simplify the Covid vaccination schedule in the United States — aligning it more closely with the annual flu shot. In another similarity to the flu shot, the FDA is considering whether the Covid vaccine should be updated at least once a year, based on what strains are in circulation. Dr. Anna Durbin, a vaccine researcher at Johns Hopkins University in Baltimore, said simplifying the Covid vaccine schedule makes sense.

Covid hospitalizations are rising in the United States, even as hospitalizations for respiratory syncytial virus and the flu continue to fall. For the week ending Dec. 24, around 18,800 people were hospitalized with flu, down from around 20,700 hospitalizations the week prior. RSV hospitalization rates have fallen significantly since their peak in mid-November of 5.1 hospitalizations per 100,000 people. The seven-day average of daily Covid hospitalizations reached 42,140 on Friday, an increase of 4.2% from two weeks ago, according to an NBC News tally. The CDC recommends up-to-date Covid vaccines for everyone ages 6 months and older, as well as annual flu shots.

Moderna’s updated Covid booster appears to increase the immune response to omicron subvariants BA.4 and BA.5, as well as another subvariant, called BQ.1.1, that's gaining ground in the United States, the company said in a release Monday. The results are based on blood samples taken from 511 adults who got the updated booster, which targets BA.4 and BA.5, along with the original coronavirus strain, in a single shot. In people who got the updated booster, neutralizing antibodies against BA.4 and BA.5 were about fivefold higher in those with a previous Covid infection and sixfold higher in those without a documented infection, the company said. Moderna also said an additional analysis of 40 people found the updated booster demonstrated “robust neutralizing activity” against the subvariant BQ.1.1, though the response wasn’t as strong as what was seen against BA.4 and BA.5. Earlier this month, Pfizer and BioNTech said their updated booster shot generated a stronger immune response against BA.4 and BA.5 compared with their original Covid vaccine.

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