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Cathie Wood, CEO of Ark Invest, speaks during an interview on CNBC on the floor of the New York Stock Exchange (NYSE) in New York City, February 27, 2023. Cathie Wood is defending her underperforming ARK Innovation exchange traded fund following a rocky stretch. Since then, the fund has underperformed, fueling skepticism over the Ark Invest CEO's investment strategies. She called out the multiomics life sciences and health care sectors as the biggest drag on the fund. "We think we're a very good complement to the broad-based benchmarks out there, because we don't look anything like them," she said of her fund.
Persons: Cathie Wood, CNBC's, Wood Organizations: Ark Invest, CNBC, New York Stock Exchange, Innovation, Ark, Intellia Locations: New York City
Gary Allen Montelongo won $10,000 for a science project on train derailment. Montelongo built and coded an experiment on railroad suspension, then won a national competition. AdvertisementThe internship ended, but Montelongo couldn't get the derailment off his mind, so he went down to the train tracks near his house. Then he built three sets of model railroad tracks out of foam and fitted them with three different types of springs: fresh new springs, midlife springs, and old, worn-out springs. This mimicked the different suspension systems he'd seen at the train tracks near his home.
Persons: Gary Allen Montelongo, Montelongo, , Lisa Fryklund, Ajmera, Montelongo couldn't Organizations: Service, Fisher Scientific, Junior, Society for Science, Broadcom, Federal Railroad Administration, University of Texas, NASA, SpaceX Locations: Ohio, East Palestine , Ohio, University of Texas Rio Grande
A pig has tested positive for H5N1 bird flu in a backyard farm in Oregon. The H5N1 bird flu was detected in a pig in Oregon, the first instance of a swine infection in the US, officials announced on Wednesday. Pigs get both bird flu viruses and human flu viruses, making them a genetic mixing bowl where H5N1 could gain genetic mutations that help it spread between humans. AdvertisementWhy pig infection could be a tipping pointPigs play host to both bird flu viruses and human flu viruses. Inside a pig, the H5N1 bird flu virus could pick up genetic mutations that help it adapt to better infect human bodies.
Persons: , Stacey Schultz, Cherry, Jude Children's, Jeremy Farrar, Diego Vara, Florian Krammer, Cynthia Goldsmith, Jackie Katz, Schultz, Richard Webby, Jude, Robert Giroux Organizations: Service, St, Jude Children's Research, World Health Organization, Reuters, US Department of Agriculture, USDA, Icahn, of Medicine, STAT, CDC, AP, WHO Locations: Oregon, South America, Sao Jose, Norte, Brazil, New York, St, New York City
23andMe said it appointed three new independent directors to its board on Monday. Advertisement23andMe has appointed three new independent directors to its board following the mass resignation of all seven of its previous members last month. The seven previous board members resigned in September in a letter addressed to Wojcicki, citing the company's direction. Wojcicki shared a proposal to take 23andMe private in a July SEC filing, which was reviewed by a special committee formed by the board of directors. The special committee responded less than a week later, writing they were "disappointed" in the proposal.
Persons: 23andMe, , Andre Fernandez, Mark Jensen, Jim Frankola, Fernandez, Jensen, Frankola, Anne Wojcicki, Kimberly White, Wojcicki Organizations: Service, SEC, Deloitte, 23andMe Board, Company, Business Locations: American
CNN —Researchers have connected the identity of skeletal remains found in a well at Norway’s Sverresborg castle to a passage in a centuries-old Norse text. The text is rich in detail, including full names, locations, battles and military strategy as well as Sverre’s speeches. For the latest study, Martin and his colleagues wanted to bring together historical, archaeological and genetic context for Well-man’s remains. Excavations in 2014 and 2016 unearthed more of Well-man's remains, including his skull. Norwegian Institute for Cultural Heritage ResearchA surprising portrait of Well-manAn initial radiocarbon dating analysis helped the research team confirm that Well-man’s remains were about 900 years old, which aligns with the timeline in the Sverris saga.
Persons: King Sverre Sigurdsson, , It’s, , Michael D, Martin, they’re, King Sverre, King Sigurd Munn, Sverre, Munn, , Dr, Martin Ellegaard, Agnar Helgason, King Sverre’s, ” Martin, ” Ellegaard, Maja Krzewińska, Krzewińska, ” Krzewińska, he’s Organizations: CNN —, Cell Press, Norwegian University of Science, Technology’s University Museum, Roman Catholic Church, Norwegian Institute for Cultural Heritage, Technology, Palaeogenetics Locations: Norway, Trondheim, Europe, Bergen, Sverresborg, what’s, , Stockholm, Sweden
The Summary New research offers insight into the evolutionary history of amylase genes, which are key to our ability to eat and digest starchy food. Amylase genes produce an enzyme in saliva and the gut that’s key to breaking down starches into sugar. New research published Thursday in the journal Science suggests the amylase gene has a much longer evolutionary history than scientists previously thought. Some studies have suggested that populations with higher numbers of amylase copies tend to eat more starch, though more research is needed to explore those theories. … There are things that just exist.”Both recent studies relied on a relatively new technology to analyze genetic material from ancient humans.
Persons: , Omer Gokcumen, Gokcumen, amylase, Peter Sudmant, ” Sudmant, Sudmant, ” Gokcumen Organizations: University at Buffalo, University of California Locations: Europe, Africa, Berkeley, Siberia, Romania
Hinton isn’t the first Nobel laureate to warn about the risks of the technology that he helped pioneer. Irene Joliot-Curie and Frederic Joliot shared the Nobel Prize for chemistry in 1935. AFP/Getty Images1945: Antibiotic resistanceSir Alexander Fleming shared the 1945 Nobel Prize in medicine with Ernst Chain and Sir Edward Florey for the discovery of penicillin and its application in curing bacterial infections. “I, for one, would not shrink from that challenge.”Jennifer Doudna won the Nobel Prize in chemistry in 2020 for her work on a new method of gene editing. Nobel Prize Outreach/Brittany Hosea-Small/Handout/Reuters2020: Gene editingFour years ago, Jennifer Doudna and Emmanuelle Charpentier shared the Nobel Prize in chemistry for the development of a method for genome editing called CRISPR-Cas9.
Persons: Geoffrey Hinton, , ” Hinton, John Hopfield “, Hinton, Hinton isn’t, Irene Joliot, Curie, Frederic Joliot, Marie, Pierre Curie, Joliot, , Sir Alexander Fleming, Ernst Chain, Sir Edward Florey, Fleming, underdose, Jeffrey Gerber, ” Gerber, ” Paul Berg, Tobbe, Paul Berg, Berg, Joanna Rose, it’s, Jesse Gelsinger, ” Jennifer Doudna, Brittany Hosea, Gene, Jennifer Doudna, Emmanuelle Charpentier, ” Doudna, “ We’ve, ” CNN’s Christian Edwards, Katie Hunt Organizations: CNN, Google, University of Toronto, Princeton University, Hulton, Getty, Children’s Hospital of Philadelphia, World Health Organization, Nobel, Innovative Genomics Institute Locations: AFP, , Stockholm
Thomas Gnoske, a collections manager at the museum, first spotted thousands of hairs trapped within the lions’ teeth when he examined their skulls in the 1990s. “Our analysis showed that the historic Tsavo lions preyed on giraffe, human, oryx, waterbuck, wildebeest, and zebra, and we also identified hairs that originated from lions. The Tsavo lions were maneless, like this adult male lion. The combined efforts opened a treasure trove of data about the lions’ prey as well as about the predators themselves. “It suggests that the Tsavo lions may have either traveled farther than previously believed, or that wildebeest were present in the Tsavo region during that time,” de Flamingh said.
Persons: John Henry Patterson, Patterson, Thomas Gnoske, , Alida de Flamingh, Gnoske, Julian Kerbis Peterhans, Kerbis Peterhans, David Sewell, Kerbis, Nduhiu, de Flamingh, Ripan, Andrew Wasike, Flamingh, ” de Flamingh, “ Patterson, John Warburton, Lee, Aditya Dicky Singh, Malhi, Love Dalén, Dalén, wasn’t, ” Gnoske Organizations: CNN, Uganda Railway, Chicago’s Field, Field Museum, University of Illinois, Field, The, Roosevelt University, Alamy, National Museums of, University of Nairobi, Anadolu Agency, Getty, Stockholm University, Locations: Kenya, Uganda, University of Illinois Urbana, Champaign, Chicago, Samburu, National Museums of Kenya, Tsavo, Cape, Africa
5 Nobel-worthy discoveries that haven’t won the prize
  + stars: | 2024-10-05 | by ( Katie Hunt | ) edition.cnn.com   time to read: +8 min
The first human genomeThe mapping of the human genome has had a huge impact on biology and other fields. The output from a DNA sequencer is shown in this undated image from the National Human Genome Research Institute. But one reason the project may not have earned a Nobel Prize is the sheer number of people involved in the feat. The Nobel Prize in physiology or medicine will be announced on Monday, followed by the physics prize on Tuesday and the Nobel Prize in chemistry on Wednesday. The Nobel Prize for literature will be announced on Thursday and the Nobel Peace Prize on Friday.
Persons: Alfred Nobel, Nobel, Carsten Snejbjerg, Svetlana Mojsov, Joel Habener, Lotte Bjerre Knudsen —, Lasker, Knudsen, Hassabis, John Jumper, Lester Cohen, David Pendlebury, Pendlebury, “ Nobel, David Baker, , Boris Roessler, We’re, Jeffrey Gordon, Robert J, Glaser, Louis, Gordon, Claire King, Barack Obama, Drew Angerer, Mary, King Organizations: CNN, Stockholm —, Human Genome Research, Nordisk, Bloomberg, Getty, Rockefeller University, Harvard Medical School, Novo Nordisk, Clarivate’s Institute for Scientific Information, Google, Institute for Protein, University of Washington School of Medicine, Washington University, of Locations: Swedish, United States, United Kingdom, France, Germany, Japan, China, Hillerød, Denmark, Los Angeles, St
London CNN —Scientists in the United Kingdom have stored the entire human genome on a “5D memory crystal,” in the hope that it could be used in the future as a blueprint to bring humanity back from extinction. The crystal is stored in the Memory of Mankind archive in Hallstatt, Austria. “The visual key inscribed on the crystal gives the finder knowledge of what data is stored inside and how it could be used,” said Kazansky. In 2018, Kazansky and his team used the memory crystal technology to store Isaac Asimov’s “Foundation” trilogy of science fiction books, which were then launched into space aboard a Tesla Roadster. The technology has also been used to store major documents from human history, including the Universal Declaration of Human Rights and the Magna Carta.
Persons: , Peter Kazansky, optoelectronics, , Thomas Heinis, Kazansky, Isaac Asimov’s “ Organizations: London CNN —, University of Southampton’s, Research, University of Southampton, Guinness, Southampton, Imperial College London, Tesla, Human Rights, Magna Carta Locations: London, United Kingdom, Austria
Grotte Mandrin is the only known site to have been home to alternating groups of both Homo sapiens and Homo neanderthalensis. “The Thorin population spent 50,000 years without exchanging genes with other Neanderthal populations,” Slimak said in a news release. DNA from Homo sapiens fossils from that time show that these early arrivals interbred with Neanderthals — traces of those encounters remain in present-day human populations. Archaeologists have excavated more of Thorin’s remains: 31 teeth, part of the jaw and five finger bones, so far. It’s the only known site to have been home to alternating groups of both Homo sapiens and Neanderthals, plus the earliest evidence of bow and arrow use outside Africa.
Persons: Ludovic Slimak, Thorin, , Slimak, , Mandrin, ” Slimak, Ludovic, sapiens, Chris Stringer, wasn’t, ” Stringer, ” It’s, Grotte Mandrin Organizations: CNN, France’s National, for Scientific Research, Paul Sabatier University, Genomics Locations: Rhône, Toulouse, Western Europe, Europe, Grotte, Malataverne, France, Thorin’s, Africa
Recently, DNA analysis of two skeletons from unmarked graves in a Jamestown church revealed that both people were related to West. That connection led researchers to documents proving that one of the men — Captain William West — was illegitimate, born to Thomas West’s spinster aunt, Elizabeth. An X-ray scan (left) of the spangled military sash fringed in silver (right) found in the grave of Captain William West. Jamestown Rediscovery Foundation (Preservation Virginia)Unmarked burials in colonial JamestownResearchers found four unmarked graves at Jamestown in 2014, in an Anglican church that the colonists used from about 1608 to 1616. MPI/Archive Photos/Getty ImagesWhile there wasn’t enough DNA to show immediate family ties, Wenman and Captain West both shared the haplogroup H10e.
Persons: Thomas West, Captain William West —, Thomas West’s, Elizabeth, Captain West, James Fort, , Christine Lee, Lee, Captain William West, Sir Ferdinando Wenman, , Kari Bruwelheid, ” Bruwelheid, Éadaoin Harney, William West’s, , Ferdinando Wenman’s, ” Harney, West’s, Mary Blount, West “, West, Governor Thomas West, Ferdinando Wenman, Michael Lavin, ” Lavin, ” Mindy Weisberger Organizations: CNN, Jamestown Rediscovery, Preservation, University of Mississippi, spangled, Jamestown, Smithsonian National Museum of, Harvard University, MPI, Governor, Jamestown Rediscovery Foundation, Scientific Locations: Jamestown , Virginia, Jamestown, England, Preservation Virginia, Wenman, West, Washington ,, North America
Prickles have been around for at least 400 million years, dating back to when ferns and their relatives emerged with some bearing prickles on their stems. Lonely Guy genesBy removing prickles from various species, including roses and eggplants, the authors found that a LOG gene was responsible for the prickles in about 20 types of plants studied. LOG-related genes are found in all plants, even dating back to mosses, which are regarded as the first dry-land plant, Lippman said. “(LOG genes) have been repeatedly co-opted (a biological shift in a trait’s function) in different plant species for the formation of prickles, and also repeatedly lost in lineages where prickles are lost. For agricultural purposes, removing prickles could make harvesting easier and pave the way to get lesser-known produce into grocery stores.
Persons: munch, Zachary Lippman, , Lippman, Guy, It’s, ” Lippman, , Tyler Coverdale, ” Coverdale, Coverdale, , Vivian Irish Organizations: CNN, Laboratory, University of Utah, Wings, Howard Hughes Medical Institute, University of Notre Dame, Yale Locations: Long, , New York, Yale University’s, Australia
DNA analysis sheds light on how Neanderthals disappeared
  + stars: | 2024-07-31 | by ( Katie Hunt | ) edition.cnn.com   time to read: +8 min
The analysis, published July 12 in the journal Science, showed that the two groups exchanged DNA at multiple points over the past 250,000 years, shedding light on how Neanderthals disappeared and potentially rewriting the story of how and when our Homo sapiens ancestors left Africa. Genetic detective workDuring the two earlier waves of interbreeding, the Neanderthal population absorbed human genes and the offspring stayed within Neanderthal groups, according to the new study. Russian archeologists digging inside Denisova cave located in the the Altai mountains that's been home to Neanderthals, early modern humans and the Denisovans. A skull found in Qafzeh Israel is believed to have belonged to an early modern human. The researchers’ analysis suggests that the Neanderthal population size at the time was 20% smaller than previously thought.
Persons: , Joshua Akey, Sigler, ” Akey, Nobel, Svante Pääbo, Laurits Skov, wasn’t, Akey, , Homo sapiens, Eddie Gerald, Alamy, Chris Stringer, “ I’ve, ” Stringer, De Agostini, Stringer Organizations: CNN, Lewis, Sigler Institute, Princeton University, University of California Locations: Africa, University of California Berkeley, Vindija, Croatia, Altai, East, Europe, London, Cave, Greece, Israel
CNN —A piece of woolly mammoth skin excavated from the Siberian permafrost has been found to contain fossil chromosomes in a first-of-its-kind discovery, according to a new study. The new study revealed that fossils of ancient chromosomes survive in this skin sample. But the DNA from elephants was also needed to assemble the mammoth genome. The researchers hope to use the findings to assemble the woolly mammoth genome completely. “This structural information provides insights into functions of the woolly mammoth genome that were invisible using previous genomic methods,” Heintzman said in an email.
Persons: , Erez Lieberman Aiden, Lieberman Aiden, Olga Dudchenko, Dudchenko, Elena Kizilova, Kevin Campbell, ” Campbell, ” Dudchenko, ” Aiden, , Cynthia Pérez Estrada, ” Pérez Estrada, there’s, Adam Fotos “, Marcela Sandoval, Velasco, Pérez Estrada, Peter Heintzman, ” Heintzman, Dmitry Filatov, ” Filatov, ” Hendrik Poinar, Poinar Organizations: CNN, Baylor College of Medicine, Center, Theoretical, Rice University, of Cytology, University of Manitoba, Stockholm University, Houston Astros, Center for Genome Architecture, Baylor, Rice’s, University of Copenhagen, University of Oxford, McMaster University Locations: Belaya Gora, Siberia, Canada, Stockholm, Denmark, , Sweden, paleogenomics, United Kingdom, Ontario
A Mammoth First: 52,000-Year-Old DNA, in 3-D
  + stars: | 2024-07-11 | by ( Siobhan Roberts | ) www.nytimes.com   time to read: +1 min
They probed the sample with an innovative experimental technique that revealed the three-dimensional architecture of the mammoth’s genome. Hendrik Poinar, an evolutionary geneticist at McMaster University in Canada, was “floored” — the technique had successfully captured the original geometry of long stretches of DNA, a feat never before accomplished with an ancient DNA sample. “It’s absolutely beautiful,” said Dr. Poinar, who reviewed the paper for the journal. An organism’s full genome resides in cell nuclei, in long, unfragmented DNA strands called chromosomes. “To have the actual architectural structure of the genome, which suggests gene expression patterns, that’s a whole other level,” Dr. Poinar said.
Persons: , Hendrik Poinar, , Poinar Organizations: McMaster University Locations: Houston, Copenhagen, Barcelona, Siberia, Canada
CNN —The oldest known plague victims date back to around 5,000 years ago in Europe. Genetic time travelGenetic information about pathogens can be preserved in human DNA, allowing scientists to time travel to find out about ancient diseases and how they evolved. (It’s also not possible to know for sure whether the people studied died of the plague — only that they were infected.) Karl-Göran SjögrenNonetheless, the study authors said their findings did not necessarily suggest a swift and deadly plague epidemic. Instead, the team found evidence of three distinct infection events, plus different variants of the bacterium that causes plague.
Persons: it’s, , , Frederik Seersholm, ” Seersholm, Seersholm, Yersinia pestis, It’s, Karl, Göran, , Mark Thomas, Thomas, wasn’t, he’s, ” Thomas Organizations: CNN, Lundbeck Foundation GeoGenetics, Globe Institute , University of Copenhagen, University College London Locations: Europe, Latvia, Sweden, Denmark, Northern Europe, France, it’s, Frälsegården, Scandinavia
To determine the best books of the 21st century , The New York Times Book Review and The Upshot polled hundreds of literary luminaries. Stephen King Stephen King has written more than 60 books, many of which have been adapted for film and television. Min Jin Lee Min Jin Lee has written two novels: FREE FOOD FOR MILLIONAIRES and PACHINKO, which was one of The Times’s 10 Best Books of 2017. Scott Turow Scott Turow is an attorney and writer best known for legal thrillers like PRESUMED INNOCENT and THE BURDEN OF PROOF. DU BOIS, was one of The Times’s 10 Best Books of 2021.
Persons: Stephen King Stephen King, , Ian McEwan ●, Christine Falls, Benjamin Black ●, Donna Tartt, Gillian Flynn ●, Cormac McCarthy ●, Margaret Atwood ●, Sarah Waters ●, Philip Roth ●, Viet Thanh Nguyen, , Stephen King, Min Jin Lee Min Jin Lee, Anthony Doerr ●, Katherine Boo ●, Colm Tóibín ●, Julie Otsuka ● “, Tara Westover ● “, Matthew Desmond ● “, Marilynne Robinson, Edward P, Jones, Barbara Ehrenreich ●, Phil Klay Karl Ove Knausgaard Karl Ove Knausgaard, Roberto Bolaño ● “, Maggie Nelson ● “, Elena Ferrante ● “, Ben Marcus ● “, Emmanuel Carrère ●, Kazuo Ishiguro ●, Claire Keegan ● “, Peter Handke ●, Denis Johnson ●, Svetlana Alexievich, Bonnie Garmus Bonnie Garmus, Barnes, Nehisi Coates, Barbara Kingsolver ●, Tara Westover, Matt Ridley ●, Harry Potter, Prince, Rowling ●, Dave Eggers ●, Henry David Thoreau, Laura Dassow, Ben Rice ●, Colson Whitehead ●, Timothy Egan Nana Kwame Adjei ‑ Brenyah Nana Kwame Adjei ‑, ZZ Packer, Diana Khoi Nguyen, “ Greenwood, Michael Christie, Solmaz Sharif, Min Jin Lee ● “, George Saunders ● “, Jesmyn Ward, Ted Chiang ●, George Saunders ●, Colson Whitehead, Chimamanda Ngozi, Edwidge Danticat, Aracelis Girmay, Natsuo Kirino, Roberto Bolaño ●, Francisco Goldman ●, Paul Beatty Sarah Jessica Parker Sarah Jessica Parker, Tayari Jones, Sting, Paul Murray ●, Megha Majumdar ●, Anthony Marra ●, Jonathan Franzen ●, Donna Tartt ●, Janika Oza, Patrick Radden Keefe, Sonali Deraniyagala James Patterson James Patterson, Bill Clinton, Dolly Parton, J.D . Barker, Stephen King ● “, Markus Zusak ●, Tara Westover ●, Stieg Larsson, Gillian Flynn, Rowling, Anthony Bourdain ●, Keith Richards, James Fox ●, Dennis Lehane ●, Laura Hillenbrand Elin Hilderbrand Elin Hilderbrand, “ Alice, Oliver, Charles Bock ●, Curtis Sittenfeld, Tim Winton ●, Lily King ● “, Anna Quindlen ●, Lauren Groff ● “, Maggie O'Farrell, Raven Leilani, Erin Morgenstern Annette Gordon ‑ Reed Annette Gordon, Reed, Siddhartha Mukherjee, Annette Gordon, Reed ●, Henrietta, Rebecca Skloot ●, Louis Menand ●, Isabel Wilkerson ●, Hilary, Rebecca Roanhorse Rebecca Roanhorse, Hugo, Ann Leckie ● “, Ted Chiang ● “, Kim Stanley Robinson ●, Stephen Graham Jones ●, Ken Liu ●, Djèlí Clark ●, Louise Erdrich ●, Theodore Sturgeon Marlon James Marlon James, Booker, Maria McCann ● “, Bird, James McBride ●, Alan Hollinghurst ●, Min Jin Lee ●, Skippy, Patrick French Roxane Gay Roxane Gay, Michael Chabon ●, Alicia Erian ●, Bernardine Evaristo, Kiese Laymon, Carmen Maria Machado ●, Zadie Smith, Emma Donoghue ●, Ann Patchett Jonathan Lethem Jonathan Lethem, Eugene Lim ●, Olga Ravn ●, Percival Everett ●, Keith Ridgway ●, Renee Gladman ●, Lydia Millet ● “, Helen DeWitt ● “, Robin McLean ●, Christopher Sorrentino Sarah MacLean Sarah MacLean, Angelina M, Lopez ● “, Lisa Kleypas ●, Jennifer Crusie ●, Circe, Madeline Miller, Kresley Cole ●, Beverly Jenkins ● “ Georgie, Kate Clayborn ● “ Hana Khan, Uzma Jalaluddin, Milla Vane ● “, Sherry Thomas Ed Yong Ed Yong, Bel Canto, Ann Patchett, Nana Kwame Adjei, Abed Salama, Nathan Thrall, Mohsin Hamid ● “, Helen Macdonald ● “, Jenny Odell ●, Julie Otsuka, Amal El, Max Gladstone ●, Hernan Diaz, Thomas Chatterton Williams Thomas Chatterton Williams, Hagar's, Jones ●, Catherine Lacey ● “, Dana Spiotta, Joan Silber ● “ Malcolm X, Manning Marable, Alice Munro ●, Hua Hsu, Veronica, Mary Gaitskill ●, Isabel Wilkerson Paul Tremblay Paul Tremblay, Mark Z, Joker, Kaoru Takamura ●, Benjamín Labatut, Stephen Graham Jones, Mariana Enriquez ●, Sara Levine ●, Colson Whitehead Nick Hornby Nick Hornby, Michael Chabon, David Kynaston ●, Billy Lynn's, Ben Fountain ●, Richard Russo, Olive Kitteridge, Elizabeth Strout ●, Mark Harris ●, Adrian Nicole LeBlanc ●, Scott Turow Scott Turow, Sam Quinones ● “, Elena Ferrante, Ann Goldstein, , Timothy Snyder ●, Adam Johnson ●, Ann Goldstein ●, Daniel Kahneman ● “, Daniel Alarcón Daniel Alarcón, Oscar Wao, Junot Díaz, Claudia Rankine, Jones ● “, Adrian Nicole LeBlanc ● “, Patrick Radden Keefe Honorée Fanonne Jeffers Honorée Fanonne Jeffers, Victor Luckerson ●, Alice Walker ●, Toni Morrison ●, Toni Morrison ● “, Ibram X, Tiya Miles ●, Isabel Wilkerson Lucy Sante Lucy Sante, Uwe Johnson, Damion Searls, Jeremiah Moss ●, Sigrid Nunez ●, Ian Penman, Mike DeCapite ●, Rachel Kushner ●, Ed Park ●, Svetlana Alexievich Gary Shteyngart Gary Shteyngart, Pitchaya Sudbanthad, Amy Hempel, Amy Hempel ● “, Colm Tóibín, Joseph O’Neill ●, Rachel Cusk ●, Tony Judt ●, Isabel Wilkerson Anand Giridharadas Anand Giridharadas, Jane Mayer ●, Andrew Solomon ● “, Hanya Yanagihara, Suketu Mehta, Karl Ove Knausgaard ●, Asne Seierstad, Joan Didion Jessamine Chan Jessamine, Barack Obama, Tang, Chloé Cooper Jones, Andrea Elliott ● “, Jenny Erpenbeck, Lauren Groff ●, Cathy Park Hong, Sheila Heti ●, Dorothy Roberts Michael Robbins Michael Robbins, Michael Robbins, Kristin Ross ●, Lauren Berlant, Andreas Malm ●, Anahid Nersessian, “ Lila, Mike Davis ●, Chelsey Minnis, Fred Moten ●, Mary Gaitskill Alma, Alma Katsu, Jonathan Strange, Norrell, Susanna Clarke ● “, Sarah Waters, Julie Otsuka ●, Audrey Niffenegger ●, Megan Abbott Megan Abbott, Edgar, Joyce Carol Oates, Kate Atkinson ●, Robert Kolker ●, Oyinkan Braithwaite ●, Daniel Woodrell ●, Joan Didion Joshua Ferris Joshua Ferris, Hemingway, Anne Enright, Patricia Lockwood ●, Paul Harding ●, Ann Napolitano Ann Napolitano, David Mitchell ●, Yaa Gyasi, Emily St, John Mandel ●, John Irving John Irving, OWEN MEANY, John Boyne, Paul Theroux, Abraham Verghese ●, James Salter ●, Nix, Nathan Hill, Edmund White ●, Peter Matthiessen ●, Michael Ondaatje ●, Jeanette Winterson Tiya Miles Tiya Miles, Frederick Douglass, David W, Blight, Andrew Sean Greer ●, Michael Pollan ●, Dara Horn ●, Stephen Greenblatt ●, Jami Attenberg Jami Attenberg, Ada Limón ●, Jonathan Franzen, Alison Bechdel, Sloane Crosley, Alexander Chee ●, Patti Smith ●, Morgan Parker ●, Sara Novic Stephen L, Carter Stephen L, Carter, Deirdre McCloskey ●, Mohsin Hamid ●, Virginia Postrel, Umberto, Geraldine Brooks ●, Richard Powers ●, Jane Brox ●, David Bentley Hart, Lesley Nneka Arimah, Sarah Schulman Sarah Schulman, Mattilda Bernstein, Natasha Trethewey ●, Adania Shibli, Ned Blackhawk ●, Stephanie E, Rogers, Martha S, Steven W, Raja Shehadeh ●, Hugh Ryan Elizabeth Hand Elizabeth Hand, Rene Denfeld ●, Henry Darger, John M, MacGregor ● “, Dan Chaon ● “ James Tiptree Jr, Julie Phillips ●, Kelly Link, Morgan Talty ●, Robert Macfarlane ●, William Gibson Dion Graham Dion Graham, Jonathan Eig’s, Colson Whitehead’s CROOK, Omar El Akkad, Wolf, Marlon James ● “, Winfred Rembert, Cixin Liu ● “, Dave Eggers ● “, George Floyd, Robert Samuels, Toluse, Jonathan Eig ●, Jonathan Eig ● “ Washington, Jeremy Denk Jeremy Denk, David Foster Wallace ●, Jeff, Geoff Dyer ●, Hanif Abdurraqib, Elif Batuman, Alex Ross ●, Kate Molleson Morgan Jerkins Morgan Jerkins, Zora Neale Hurston, Haruki Murakami ●, Masha Gessen ●, Safiya Sinclair ● “, Carmen Maria Machado ● “, Imani Perry, Jesmyn Ward Michael Roth Michael Roth, Amy Bloom, Saidiya Hartman, Valeria Luiselli ●, Jon Fosse, Daniel Kahneman ●, Ben Lerner ●, Jennifer Egan Organizations: New York, Argonauts, J.K, Railroad, Corrections, , A.M, Harvard University, OF, Metaphysical, Suns, Ministry, Indians, The New York Times, Hawthorn, Child, Roberto Bolaño ● “, New Yorker, NPR, University of Oklahoma, DU BOIS, PEN, , Yale Law School, THE, Umberto Eco, Beginners, MacArthur Foundation, Wesleyan University, Topeka School Locations: , Brooklyn, Norwegian, Ben Marcus ● “ The, Nantucket, OF MONTICELLO, Monticello, , BROOKLYN, Britain, Jones ● “ Lincoln, Feral, Bangkok, Susanna Clarke ● “ Lincoln, Burma, Texas, Jonathan Eig ● “, “ Austerlitz, Venice, Death, Varanasi, America, Lorraine
Named for the first two letters of "breast" and "cancer," a positive result would place my odds of developing breast cancer at 87%. For me, an adult, it was a wake-up call to get ahead of breast cancer. We also had a family history of breast cancer in common, but her mother, who'd been diagnosed in her 20s, had caught it early and survived. And most important of all, on a scale of one to infinity, how relieved did she feel now that breast cancer was no longer a threat? I asked for the BRCA test, and my doctor agreedDuring my next prenatal checkup, I asked my doctor to arrange a BRCA test.
Persons: , I'd, Stephanie, Angelina Jolie, who'd, Bikur Cholim, she'd, Gila Pfeffer Organizations: Service, Business, Genome, The New York Times Locations: The
The Science of Dogs
  + stars: | 2024-06-30 | by ( Emily Anthes | ) www.nytimes.com   time to read: +1 min
My career as a science journalist began with a story on canine genetics. Over the two decades since, I have seen dogs transform from an academic afterthought to the new “it” animal for scientific research. In the United States alone, tens of thousands of dogs are now enrolled in large, ongoing studies. In today’s newsletter, I’ll explain why dogs have become such popular scientific subjects. Big dog dataFirst, an important clarification: Dogs have long been the subject of invasive medical experiments, similar to lab rats and monkeys.
Persons: Tasha, That’s Locations: United States
How Science Went to the Dogs (and Cats)
  + stars: | 2024-06-30 | by ( Emily Anthes | ) www.nytimes.com   time to read: +1 min
This article is part of our Pets special section on scientists’ growing interest in our animal companions. Every dog has its day, and July 14, 2004, belonged to a boxer named Tasha. “And everything has kind of exploded since then,” said Elaine Ostrander, a canine genomics expert at the National Human Genome Research Institute, who was part of the research team. In the 20 years since, geneticists have fallen hard for our canine companions, sequencing thousands upon thousands of dogs, including pedigreed purebreds, mysterious mutts, highly trained working dogs, free-ranging village dogs and even ancient canine remains. (“I didn’t want to study dogs,” said Alexandra Horowitz, who has since become a prominent researcher in the field of canine cognition.)
Persons: Tasha, , Elaine Ostrander, pedigreed, Monique Udell, Alexandra Horowitz Organizations: National Institutes of Health, Human Genome Research, Oregon State University,
"It's the only complete adult Pleistocene wolf that's ever been found, so that in itself is really remarkable and completely unique," he added. AdvertisementThe wolf's stomach may hold its last meal and much moreScientists are investigating the wolf's stomach for signs of its last meal and ancient microbes. This discovery is just part of a larger collaboration to study other ancient animals, including fossil hares, a horse, and a bear. The researchers previously studied a wolf head from the Pleistocene era and have another wolf fossil awaiting dissection. Any ancient viruses or bacteria in the guts of the Yakutia wolf could help researchers better understand the microbes hiding inside permafrost creatures.
Persons: , Robert Losey, wasn't, Losey, Jean, Michel Claverie, Claverie Organizations: Service, Eastern Federal University, Business, University of Alberta, Institute of Experimental Medicine, Eastern, CNN Locations: Yakutia, Russia, North, Yakutsk, Yukon
A team of international academics successfully sequenced the genomes of each of the eight baobab species, examining their relationship with one another and concluded that they originated in Madagascar. "Avenue of the Baobabs" in Western Madagascar is one of the most spectacular collections of the unusual trees. Gavinevans/Creative CommonsOnly one baobab species is not included in the IUCN’s Red List of Threatened Species: A. digitata, which populates mainland Africa. The likelihood of finding fossil evidence to rubberstamp the conclusions of the genetic data is slim, Dr. Wan conceded. So perhaps these majestic trees may retain some of their mystery after all.
Persons: , Wan Jun, Nan, Wan, Seheno, Andriantsaralaza, , Dr,  Organizations: CNN, Biologists, Gardens, Royal Botanic Gardens, University of Antananarivo, Queen Mary University of London, IUCN, USAID Locations: Madagascar, Africa, Australia, Wuhan, Hubei, China, baobabs, Queen, Western Madagascar,
In the 19th century, Charles Darwin and Jean Baptiste Lamarck suggested that giraffes evolved long necks to help them snatch leaves on trees. A later theory usurped Darwin and Lamarck's, suggesting that male giraffes evolved long necks to fight and compete for female mates. "I realized that the important question was, 'Do males have proportionally longer necks compared to the rest of their body?'" Cavener said this may be the first study to suggest that females, not males, are the reason for giraffes' long necks. That's important not only for understanding giraffe evolution but how male and female giraffes behave differently, which could help with conservation efforts.
Persons: , Charles Darwin, Jean Baptiste Lamarck, Darwin, Lamarck, Douglas Cavener, wasn't, Cavener, Art Wolfe, Zoe Raw, Raw Organizations: Service, Business, Biology, Penn State, International Union for Conservation Locations: Tanzania, Kenya, East Africa, Darwin, bushmeat
Then, three healthy ferrets were placed in the same enclosures with three of the sick animals. These animals could touch, nose and lick the sick animals, and all of them became ill.Next, the CDC tested airborne transmission by putting three healthy ferrets into an enclosure where they could breathe the same air as sick animals but couldn’t touch them. In her lab, ferrets with previous exposures to seasonal flu strains didn’t get as sick when exposed to new flu viruses compared to those with no prior exposure to seasonal strains. How much help we might get from past exposures to flu viruses is difficult to predict, however, which is why vaccination would still be important to tune up our immunity. They never spread the virus to any of the other animals in the facility — including themselves.
Persons: Mark Naniot, Naniot, , , It’s, Jeremy Farrar, Jesse Bloom, Fred Hutch, ” Naniot, Naniot hadn’t, Scott Weese, Weese, there’s, Covid, Rick Bright, Sanjay Gupta, Bright, Erin Sorrell, Zahl, Seema Lakdawala, hasn’t, ” Bright, Dr, Richard Webby, Jude Children’s, “ It’s, Ducks, Michael Osterholm, “ I’ve, he’s Organizations: CNN, Swiss Army, World Health Organization, Fred Hutch Cancer Center, University of Guelph, US Centers for Disease Control, CDC, Research, Development Authority, CNN Chief, Bright Global Health, Johns Hopkins Center for Health Security, Getty, Emory University, STAT, Administration, Strategic Preparedness, USDA, Jude Children’s Research, Infectious Disease, University of Minnesota, CNN Health Locations: Wisconsin’s, United States, Seattle, Canada, Texas, Vadso, Finnmark, Norway, AFP, Finland, St, Wisconsin
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