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The only approved treatments for Alzheimer’s disease are medications with limited effectiveness and a risk of severe, sometimes deadly, side effects. Researchers found that when the device was aimed at the right spot in the brain, it could slow the development of symptoms, such as memory loss, compared to an inactive treatment. In Alzheimer’s, nerve cells in the brain at some point start to dysfunction, leading to the debilitating symptoms of memory loss. What’s more, during the yearlong TMS trial, participants receiving the experimental treatment showed little decline in their abilities to perform the activities of daily living. Sinaptica’s weekly brain stimulation therapy is intended to strengthen connections in areas of the brain that control memory.
Persons: Giacomo Koch, ” Koch, Koch, Irina Skylar, Scott, , , Lawrence Honig, Honig, Ryan Darby, Darby Organizations: University of Ferrara, Sinaptica, NBC News, TMS, Alzheimer’s Association, Food and Drug Administration, Stanford University’s Center, Memory Disorders, Columbia University Irving Medical Center, Vanderbilt University Medical Center Locations: Madrid, Cambridge , Massachusetts, U.S
Not having — or losing — your sense of smell may be linked to changes in breathing that could lead to depression, social isolation or other mental and physical health problems, a new study suggests. About 72% of those completely regained their sense of smell, while about a quarter partially got their sense of smell back. Previous research has linked anosmia to a wide variety of negative outcomes, ranging from dulled emotions and depression to a shortened lifespan, the authors noted. It was a game changer.”Currently, health care providers often don’t ask about or test for anosmia, Parma said. “And when there is a pleasant smell, the brain tells the nose to increase the amount of air inhaled.
Persons: Covid, Lior, Gorodisky, ” Gorodisky, anosmia, Valentina Parma, , Parma, ” Parma, “ Covid, Dr, Jonathan Overdevest, Overdevest, Alzheimer’s, Benjamin tenOever, ” tenOever Organizations: Nature Communications, National Institutes of Health, Weizmann Institute of Science, Senses Center, anosmia, Columbia University Irving Medical, New York University Langone Medical Locations: Rehovot, Israel, Philadelphia, Parma, New York City
Smartphone Free Childhood, a recently founded U.K. organization is aimed at uniting parents who are not giving their kids smartphones. Organize with other parentsBeing the only parent refusing to give your child a smartphone can be isolating for both you and your kid, Rausch said. "The class parents, as a collective, agreed that they would postpone giving their kids cell phones until they entered middle school. Start the conversation earlyPike and Rausch advise starting the conversation around smartphones from childhood so that your child isn't surprised later on. Pike said that even making a habit of giving a bored child a smartphone as entertainment can become a major issue down the line.
Persons: Kathleen Pike, Columbia's Pike, Zach Rausch, Jonathon Haidt's, Rausch, Johnny, Pike, we've, it's, isn't, Melanie Hempe, you've, They're Organizations: Columbia University Irving Medical Center, CNBC, New York University Stern School of Business, New York Times Locations: U.S
CNN —Two shots a year of a drug currently used to treat HIV infections were dramatically effective at preventing infections in a study among young women and adolescent girls in Africa. The twice-yearly injection of the drug lenacapavir can provide total protection against HIV infections, demonstrating 100% efficacy in Phase 3 trial data released by drugmaker Gilead and published Wednesday in the New England Journal of Medicine. The twice-a-year injections of lenacapavir could add another option at preventing HIV infections to the toolbox. The latest Phase 3 findings are part of Gilead’s PURPOSE program, which comprises five HIV prevention trials around the world. “While Gilead awaits additional phase 3 clinical trial data and the potential regulatory filings for HIV prevention administered twice-yearly, it is too early to state the price of lenacapavir for PrEP (prevention).
Persons: drugmaker Gilead, ” Linda, Gail Bekker, Desmond Tutu, , , Dan Barouch, hasn’t, Gilead, Dr, Jason Zucker, Barouch, ” Zucker, Lenacapavir, Gilead spokeperson, lenacapavir, Sanjay Gupta, Daniel O’Day Organizations: CNN, New England, of Medicine, International AIDS, PrEP, University of Cape, International AIDS Society, Center, Virology, Vaccine, Beth Israel Deaconess Medical, United, lenacapavir, Columbia University Irving Medical Center, , US Food and Drug Administration, AIDS, CNN Health, People’s Medicines Alliance, Medicines Locations: Africa, Munich, University of Cape Town, South Africa, Uganda, Argentina, Brazil, Mexico, Peru, Thailand, United States, United Kingdom, Germany, Gilead, Europe
Meinert started going to food therapists at five years old, but it wasn't until she tried psilocybin — the psychedelic property in "magic" mushrooms — that she felt her symptoms fade. A lifelong struggle with foodDanielle Meinert eating Mexican food with ingredients that she used to find scary. Still, Meinert felt progress was agonizingly slow and involved "force-feeding" herself foods that scared her. An eating disorder treatment in 'magic' mushrooms? Unlocking motivation to do hard thingsDanielle Meinert happily eating a range of foods after her psilocybin session.
Persons: , Danielle Meinert, Meinert, ARFID, Michael Pollan's, Johns Hopkins, Natalie Gukasyan, Gukasyan, nervosa, I'd, you've Organizations: Service, Business, Columbia University Irving Medical Center
CNN —About 1 in every 10 people in the US who uses Adderall or similar combination drugs to treat attention-deficit/hyperactivity disorder (ADHD) has been affected by an ongoing shortage, a new analysis suggests. The US Food and Drug Administration announced that Adderall was in shortage in mid-October 2022, and the share of people with ADHD who filled their prescriptions for Adderall and related medications plunged in the following months. Patients were considered eligible for a monthly prescription fill if they had filled one within the previous two years. Prescriptions for medications used to treat ADHD surged during the Covid-19 pandemic, especially among young adults and women, one study found. But it’s been about a year and a half since she’s been able to fill her Adderall prescription in a “totally uneventful” way, she said.
Persons: Adderall, Robert Califf, Anne Milgram, David Goodman, , Mary Beth King, it’s, she’s, ” King, King, ” Goodman, John Mitchell, ” Mitchell, they’re, ’ ”, , , Dr, Sanjay Gupta, hasn’t Organizations: CNN, US Food and Drug Administration, Drug, of Psychiatry, Behavioral Sciences, Johns Hopkins School of Medicine, American Professional Society, New, Psychiatric Institute, Columbia University Irving Medical Center, Duke University School of Medicine, Get CNN, CNN Health Locations: Sweden
And prescriptions for ADHD medications surged during the Covid-19 pandemic, especially among young adults and women. Treatment with ADHD medication especially reduced the risk of death from “unnatural” causes, including accidental injury, suicide and accidental poisoning such as drug overdose. While ADHD medications are relatively short-acting, experts say it’s important to consider the broader outcomes along with the immediate benefits. When it comes to “natural” causes of death such as medical conditions, however, the new study found that medication did not significantly affect mortality among ADHD patients. For these reasons, the link identified between treatment with medication and reduced mortality risk cannot be considered a direct cause-and-effect.
Persons: , , John Mitchell, ” Mitchell, Dr, Sanjay Gupta, ” CNN’s Kristen Rogers Organizations: CNN, New, Psychiatric Institute, Columbia University Irving Medical Center, Duke University School of Medicine, CNN Health Locations: Sweden, United States
From 1999 to 2020, Black women were on average six times more likely than white women to be a victim of homicide, according to a new study, with researchers pointing to structural social inequities as fueling their higher risk. In 2020, the homicide rate for Black women was 11.6 homicides per 100,000 women, compared to a relatively static rate of 3 per 100,000 among white women in the same age group. Wisconsin, in particular, saw the largest disparity of any state overall, with the homicide rate among Black women more than 20 times that of white women from 2019 through 2020. Study authors said this marks a “disturbing increase” from the period between 1999 and 2003, when the homicide rate among Black women was six times that of white women. “Structural racism might provide insight as to why Black women, regardless of their ethnicity, face disproportionately high rates of homicide,” the study stated.
Persons: , , Bernadine Waller, ” Waller, they’re Organizations: National Institute of Mental Health, Columbia University Irving Medical, D.C, U.S . News, Wisconsin Locations: Midwest, South, West, Virginia, Alabama, Florida . Wisconsin, In Wisconsin , Missouri, Arizona, Oklahoma, Washington
King Charles and Queen Camilla are seen leaving Clarence House in London on February 6, the day after it was announced King Charles had been diagnosed with cancer. But Queen Elizabeth and King Charles, they do not want to become the story, they still want to serve their public. In the fullness of time, I would like to think King Charles will talk about his treatment.”Britain's King Charles III poses for a portrait in Buckingham Palace's Throne Room after his official coronation in May 2023. From left are Camilla, Duchess of Cornwall; Prince Charles; Queen Elizabeth II; Prince Philip; Prince William; and Catherine, Duchess of Cambridge. From left are Prince Charles; the Queen; Prince Louis; Catherine, the Duchess of Cambridge; and Princess Charlotte.
Persons: London CNN — Britain’s King Charles III, Buckingham, Charles, King Charles, Queen Camilla, Clarence, Toby Melville, King, Rishi Sunak, Sunak, , Sunak’s, Charles ’, Chris Jackson, , Kate Williams, Joe Biden, Matthew Chattle, survivorship, “ Jill, “ You’re, Anil Rustgi, Herbert, ” Rustgi, Sally Bedell Smith, George VI, ” King George VI, Prince Charles, Prince Harry, Emily Nash, It’s, Princes William, Harry, Andrew, Edward, Anne, Beatrice, Nash, Princess, Wales, She’s, hasn’t, Catherine, ” Williams, Kristina Kyriacou, ITV’s, They’ve, Kyriacou, she’d, Queen Elizabeth, ” Britain's King Charles III, Hugo Burnand, Princess Elizabeth, Elizabeth, Prince Philip, Prince Charles and Princess Anne, Eddie Worth, Margaret, Hulton, Sir Gerald Creasy, Paul Popper, Princess Margaret, Queen Elizabeth II, Prince, Popperfoto, Prince Edward, Princess Anne, Richard Nixon, William Lovelace, Serge Lemoine, David McFall, Anwar Hussein, Tim Graham, Camilla Parker Bowles, Lady Diana Spencer, Princess Diana, William, Diana, David Levenson, Johnny Eggitt, Nelson Mandela, David Thomson, Princess Diana's, Jayne Fincher, Thomas Coex, Adrian Dennis, Chris Ison, Prince of, Camilla, Matt Dunham, Prince William, Kate Middleton, James Devaney, FilmMagic, Andrew Milligan, Barack Obama, Chris Radburn, Duchess of Cornwall, Catherine , Duchess of Cambridge, Dominic Lipinski, Alessandro Bianchi, Mohd Rasfana, Andrew Parsons, Prince Charles , Prince Andrew, Duchess Camilla, Meghan Markle, Jonathan Brady, Max Mumby, He's, Prince George, Princess Charlotte, Prince Louis, Meghan, PoolAP Charles, Tim P, Paul Chiasson, Ben Stansall, Duchess, Cambridge, Hannah McKay, Reuters Charles, Liz Truss, Yui Mok, Queen Consort, Victoria Jones, Volodymyr Zelensky, Zelensky, Aaron Chown, Handout, Dan Kitwood, Andrew Matthews, Sarah Tilotta, Toby Hancock, CNN Charles, Giles, Jane Barlow, Emmanuel Macron, Benoit Tessier, Peter Nicholls, Britain's King Charles III, Estelle Paranque Organizations: London CNN, Clarence House, Reuters, CNN, BBC, British, Getty, Royal, Publishing, Macmillan Cancer, Cancer Research, Herbert Irving Comprehensive Cancer, Presbyterian, Columbia University Irving Medical Center, Topical Press Agency, Royals, CNN’s Royal, Buckingham Palace, Central Press, Hulton, Hulton Deutsch, Westminster Abbey, Keystone, Royal Navy, Queen, Trinity College , Cambridge, Bettmann, Hulton Royals, Cheshire Regiment, Spice, Westminster Hall, Royal Horticultural Society's, Chelsea, London Palladium, BBC Scotland's, Office, Zephyr, Army Air Corps, Sandringham, Royal Air Force, Whitby, Imperial State Crown, Royal Military Academy Sandhurst, Cathedral, Scotland, King, London Clinic, Northeastern University London Locations: London, British, Dubai, United Arab Emirates, Buckingham Palace, United Kingdom, NewYork, Queen, Windsor, Wales, Buckingham, Malta, Westminster, France, Washington, Kenya, West Berlin, Canada, Cirencester, England, Canterbury, India, Manchester, Papua New Guinea, Toronto, AFP, Balmoral, Balmoral , Scotland, Paris, Ashbourne, Ranville, Prince of Wales, Amatrice, Borneo, St, John's, Newfoundland, Labrador, Nyamata, Rwanda, St James's, Hamburg, Germany, Edward's, Edinburgh, Scotland, of Versailles, Versailles
While BE-FAST helps with finding the most common symptoms of stroke, it may not reflect the stroke experience of all people. Stroke symptoms in men vs. womenScientists have come up with several theories for why men and women experience stroke differently. If women are outliving men, they also have more time and opportunity to have a stroke, Miller added. There are treatments available to improve the survival outcomes for stroke, Kamdar said, but they are all time sensitive. Even if you’re unsure whether someone is having a stroke, Miller advised calling 911 anyway.
Persons: , Eliza Miller, Dr, Hera Kamdar, Kamdar, ” Kamdar, “ It’s, ” Miller, Miller, , , neurologists, Jocelyn Solis, Moreira Organizations: CNN, NewYork, Presbyterian, Columbia University Irving Medical Center, American Heart Association, BE, The Ohio University Wexner Medical, US Centers for Disease Control, Research Locations: United States, New York
Dr. Adrian Jacques Ambrose, 35, wants to make healthcare, especially mental-health care, more accessible. Ambrose is a senior medical director in the Department of Psychiatry at Columbia University Irving Medical Center. Columbia University Irving Medical CenterAmbrose, who goes professionally by Jacques, is driven by how confusing healthcare is. As a senior medical director in the Department of Psychiatry at Columbia University Irving Medical Center, he oversees about 50 physicians and 100 other clinicians across four clinical sites. "How do I continue to inculcate this dream of advocating for not only better healthcare, but better healthcare for vulnerable populations and minority populations?"
Persons: Adrian Jacques Ambrose, Ambrose, Columbia University Irving Medical Center Ambrose, Jacques, , David Satcher, Ambrose doesn't, Rose Organizations: of Psychiatry, Columbia University Irving Medical Center, Leadership Institute Locations: Vietnam, Hawaii
CNN —As little as one or two minutes of vigorous exercise a day could lower your cancer risk, according to a new study. Participants reported not regularly exercising in their leisure time, and they wore accelerometers to track their VILPA, or vigorous intermittent lifestyle physical activity, the study said. Adults who incorporated about 4½ minutes of vigorous activity in short one- or two-minute bouts had more than 30% lower incidence rates of cancer, the study found. “The large majority of middle aged and older adults, more than 70-80% in most countries, are not regular exercisers in leisure time, or simply never do any exercise,” Stamatakis said via email. “Previous early-stage trials (showed) that VILPA leads to rapid improvements in cardiorespiratory fitness,” Stamatakis said in an email.
Persons: Emmanuel Stamatakis, , , Stamatakis, Charles Perkins, Dana Santas, ” Stamatakis, Glenn Gaesser, Gaesser, Keith Diaz, Diaz, ” Gaesser, Santas, It’s, ’ ” Organizations: CNN’s, CNN, Charles, Charles Perkins Centre, University of Sydney, College of Health Solutions, Arizona State University, Columbia University Irving Medical Locations: Australia, New York City
It was shown in May and in fuller Phase 3 clinical trial results released at the Alzheimer’s Association International Conference on Monday to delay the disease’s progression. More than 6 million Americans are estimated to have Alzheimer’s disease, with about 1 million estimated to be in the early symptomatic stages where these drugs have shown benefit. Both Leqembi and donanemab work by clearing buildups of a protein in the brain called amyloid, a hallmark of Alzheimer’s. It’s been a hypothesis that treating Alzheimer’s earlier with amyloid-clearing drugs would yield better results; Skovronsky said the donanemab trial bore that out. “We could look at people who had mild cognitive impairment, MCI, which is the earliest stage, versus mild Alzheimer’s versus moderate Alzheimer’s,” Skovronsky explained.
Persons: Leqembi, Eli Lilly’s donanemab, Lilly, “ Donanemab, Jennifer Manly, Kacie, , Dr, Gil Rabinovici, Renaud La Joie, Daniel Skovronsky, , Skovronsky, ” Skovronsky, It’s, Eric Widera, Sharon Brangman, University of Wisconsin’s Dr, Nathaniel Chin, Donanemab, Lilly hasn’t, Lawrence Honig, Honig, White, Sanjay Gupta, Deters, ” Lilly, it’s “, it’s, there’s, Joe Montminy Organizations: CNN, Alzheimer’s Association, Food and Drug Administration, American Medical Association, Columbia University Irving Medical Center, University of California, MCI, SUNY, University of Wisconsin’s, Leqembi, FDA, donanemab, CNN Health, ” Manly Locations: Los Angeles,
CNN —The US Food and Drug Administration is expected to decide on Thursday whether to grant traditional approval to the Alzheimer’s drug Leqembi, the first medicine proven to slow the course of the memory-robbing disease. Leqembi, from drugmakers Eisai and Biogen, received accelerated approval in January based on evidence that it clears amyloid plaque buildups in the brain that are associated with Alzheimer’s disease. But because of an earlier coverage decision by CMS, which provides insurance coverage for many elderly patients with Alzheimer’s through Medicare, the drug hasn’t been widely used. People with more advanced forms of the disease may not benefit from the drug, he said, and may face increased safety risks. Broad Medicare coverage of Leqembi and similar types of medications to slow the progression of Alzheimer’s disease would probably have a big impact on the program’s spending.
Persons: drugmakers, hasn’t, , ’ ”, Joe Montminy, Lawrence Honig, “ It’s, , Honig, it’s, Leqembi, ” Honig, Georges Naasan, Sue Rottura, ” Drugmaker Eisai, “ You’re, Ivan Cheung, Eisai, ” Montminy, Dr, Sanjay Gupta Organizations: CNN, Food and Drug Administration, Medicare, Services, CMS, Columbia University Irving Medical Center, Alzheimer’s, Behavioral, CNN Health, Kaiser Family Foundation Locations: Mount, Florida
Seasonal allergies can be miserable. The sneezing, congestion and itchy, watery eyes can feel like a terrible cold that won’t go away, especially now that pollen seasons are getting longer and more intense. Not only are the physical symptoms draining, but a growing body of research also shows an association between allergic rhinitis — commonly known as hay fever — and mood disorders like anxiety and depression. The relationship between allergens and mood disorders “really is underrecognized, not only in the general population but even among health care practitioners,” said Dr. David A. Gudis, chief of the division of rhinology and anterior skull base surgery at NewYork-Presbyterian/Columbia University Irving Medical Center. But given that millions of Americans suffer from seasonal allergies, it’s an important link for both doctors and patients to understand, he added, in order to speak openly about any mental health concerns and to ensure the best possible treatments.
Study finds 45 negative health effects of added sugar
  + stars: | 2023-04-05 | by ( Kristen Rogers | ) edition.cnn.com   time to read: +7 min
CNN —There are at least 45 good reasons to cut back on added sugar, according to a new study. Copious research has shown the negative effects of excessive sugar intake on health, which has informed recommendations to limit consumption of “free” or added sugar to less than 10% of a person’s daily caloric intake. “This means that whole, intact grains don’t cause the same spikes in blood sugar that we experience when we eat simple sugars. A doughnut has around 15 to 30 grams of sugar, according to the Cleveland Clinic. Cooking and baking at home more often is one of the best ways to reduce sugar intake, Aggarwal said.
About 1 in 8 adults over 50 showed signs of food addiction, according to the survey. “We think this is also true in younger populations.”Gearhardt and her team used questions from the Yale Food Addiction Scale to measure whether older adults were experiencing core indicators of addiction. If I had emotional problems because I hadn’t eaten certain foods, I would eat them (17%, once a week). Gearhardt was a member of the group that devised the Yale Food Addiction Scale. The difference is you can’t stop eating food.”Gearhardt said that the survey results should encourage health providers to ask patients about dietary habits.
The culprit behind her illness: influenza A, the most common strain of the influenza virus currently circulating across the country. “Young children are at higher risk of hospitalization and serious complications of flu,” she added. “I don’t wish this on anyone.”The best way to protect your familyMost children with influenza will recover well at home, Lockwood explains. “Getting a flu shot is the single best way to prevent the flu,” Stockwell said. Children 6 months through 8 years who are receiving the flu vaccine for the first time should receive two doses one month apart.
NEW YORK — Two New York hospitals have agreed to pay more than $165 million to 147 former patients who have accused a former gynecologist of sexual abuse and misconduct. Last year, the two hospitals reached a settlement to establish a $71 million compensation fund with 79 of Hadden’s former patients. He currently awaits trial on separate federal charges of sexually abusing dozens of young and unsuspecting female patients for over two decades. Among Hadden’s accusers was Evelyn Yang, the wife of the former presidential candidate and New York City mayoral candidate Andrew Yang. Kathy Hochul in May will offer an avenue for what she called “countless other Hadden survivors.” The act opened a one-year window for sexual abuse claims that would otherwise have been time-barred under law.
Bebelușul s-a născut în noiembrie și a fost testat negativ la Covid-19, însă prezenta anticorpi împotriva virusului, informează Reuters, citând publicația Straits Times, care a vorbit cu tânăra mamă, Celine Ng-Chan, 31 de ani. „Medicul meu bănuiește că i-am transmis anticorpi fătului în timpul sarcinii”, a declarat Celine Ng-Chan pentru Straits Times. Ea a suferit o formă ușoară a bolii și a părăsit spitalul după două săptămâni și jumătate. Organizația Mondială a Sănătății afirmă că nu se știe încă dacă o femeie însărcinată, bolnavă de Covid-19, poate transmite virusul către făt sau în timpul nașterii. Până acum, virusul nu a fost detectat în fluidul în care stă fătul în burta mamei sau în laptele de la sân.
Persons: Reuters, Celine, Chan, Times . Ea Organizations: Straits Times, Times, Organizația Mondială a Sănătății, Medical, Columbia University Irving Locations: China, Medical New York
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