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☆ Nobel Prize in chemistry awarded for work on proteins to David Baker, Demis Hassabis and John Jumper
▼ + stars: | 2024-10-09 | by ( Christian Edwards | Katie Hunt | ) edition.cnn.com time to read: +4 min

The Nobel Prize in chemistry was awarded in Sweden on Wednesday. EXCLUSIVE: The moment John Jumper shares the news about his 2024 Nobel Prize in Chemistry. pic.twitter.com/OhNSwiKwgQ — The Nobel Prize (@NobelPrize) October 9, 2024Since the pair’s key paper was published in 2021, it has been cited more than 13,000 times. They are generally built from 20 amino acids that can be combined in endless ways. Using the information stored in DNA as a blueprint, the amino acids are linked together in our cells to form long strings.

Persons: ”, David Baker, Hassabis, John Jumper, Jonathan Nackstrand, Wednesday’s, Lasker, —, David Pendlebury, Baker, Johan Aqvist, ” Aqvist, Geoffrey Hinton, John Hopfield Organizations: CNN, Getty, Google, Clarivate’s Institute for Scientific, University of Washington Locations: Sweden, AFP, British, American, DeepMind

☆ Nobel Prize in medicine 2024 awarded for work on the discovery of microRNA to Victor Ambros and Gary Ruvkun
▼ + stars: | 2024-10-07 | by ( Christian Edwards | Katie Hunt | ) edition.cnn.com time to read: +4 min

CNN —This year’s Nobel Prize in physiology or medicine has been awarded to Victor Ambros and Gary Ruvkun for their work on the discovery of microRNA, a fundamental principle governing how gene activity is regulated. Their research revealed how genes give rise to different cells within the human body, a process known as gene regulation. The Nobel Prize committee announced the prestigious honor, seen as the pinnacle of scientific achievement, in Sweden on Monday. Ruvkun conducted his research at Massachusetts General Hospital, and is a professor of genetics at Harvard Medical School. Nobel Committee Secretary General Thomas Perlmann speaks to the media in front of a picture of this year's laureates Victor Ambros and Gary Ruvkum during the announcement of the Nobel Prize in medicine winners on Monday.

Persons: Victor Ambros, Gary Ruvkun, Ambros, ’, “, Ruvkun, General Thomas Perlmann, Gary Ruvkum, Jonathan Nackstrand, ”, Olle Kämpe, David Pendlebury, ” Pendlebury, Katalin Karikó, Drew Weissman Organizations: CNN, University of Massachusetts Medical School, Harvard University, Massachusetts General Hospital, Harvard Medical School, Getty, Clarivate’s Institute for Scientific Locations: Sweden, Massachusetts, AFP, Covid

☆ 5 Nobel-worthy discoveries that haven’t won the prize
▼ + stars: | 2024-10-05 | by ( Katie Hunt | ) edition.cnn.com time to read: +8 min

The first human genomeThe mapping of the human genome has had a huge impact on biology and other fields. The output from a DNA sequencer is shown in this undated image from the National Human Genome Research Institute. But one reason the project may not have earned a Nobel Prize is the sheer number of people involved in the feat. The Nobel Prize in physiology or medicine will be announced on Monday, followed by the physics prize on Tuesday and the Nobel Prize in chemistry on Wednesday. The Nobel Prize for literature will be announced on Thursday and the Nobel Peace Prize on Friday.

Persons: Alfred Nobel, Nobel, Carsten Snejbjerg, Svetlana Mojsov, Joel Habener, Lotte Bjerre Knudsen —, Lasker, Knudsen, Hassabis, John Jumper, Lester Cohen, David Pendlebury, Pendlebury, “ Nobel, David Baker, ”, Boris Roessler, We’re, Jeffrey Gordon, Robert J, Glaser, Louis, Gordon, Claire King, Barack Obama, Drew Angerer, Mary, King Organizations: CNN, Stockholm —, Human Genome Research, Nordisk, Bloomberg, Getty, Rockefeller University, Harvard Medical School, Novo Nordisk, Clarivate’s Institute for Scientific Information, Google, Institute for Protein, University of Washington School of Medicine, Washington University, of Locations: Swedish, United States, United Kingdom, France, Germany, Japan, China, Hillerød, Denmark, Los Angeles, St

☆ Goldman lays out the next phases of AI trade and stocks to play them
▼ + stars: | 2024-03-17 | by ( Jesse Pound | In Jesse-Pound | ) www.cnbc.com time to read: +4 min

"In addition to NVDA, investors have been focused on a broadening of the AI trade. We expect there will likely be three broad, subsequent stages of the AI trade," Hammond wrote. Goldman foresees a second phase that focuses on companies that build and maintain the infrastructure around AI. "Based on performance and valuation, investors have already started to price subsequent phases of the AI trade. An equal-weighted basket of Phase 2 stocks is up 14% during the past 6 months, largely driven by valuation expansion.

Persons: Goldman Sachs, Ryan Hammond, Hammond, Goldman foresees, Goldman, — CNBC's Michael Bloom Organizations: Nvidia, Broadcom, Foundry, Keysight Technologies, Palo Alto Networks, Intuit, Adobe, Nvidia —, Pinterest, Tenet Healthcare

☆ Seth Klarman's Baupost bought 23 million shares of this data analytics stock last quarter
▼ + stars: | 2023-11-14 | by ( Alex Harring | ) www.cnbc.com time to read: +1 min

Seth Klarman's Baupost Group snapped up millions of shares in a little-known data analytics stock in the third quarter, according to the latest regulatory fillings. The value-oriented, Boston-based hedge fund opened a 22.5-million share position in Clarivate Plc worth some $151 million in the third quarter, according to Baupost's 13F filing to the Securities and Exchange Commission. CLVT YTD mountain Clarivate shares this year Klarman picked up the stock as London-based Clarivate tumbled nearly 30% in the third quarter. Still, it's a relatively small position for Baupost, failing to crack the fund's top 10 holdings by dollar value, according to InsiderScore. The loss would be worse, but since the start of the fourth quarter, Dollar General is almost 15% higher.

Persons: Seth Klarman's Baupost, Klarman, Baupost, Willis, Watson Organizations: Securities and Exchange Commission, Jacobs Solutions, Semiconductor, Fidelity National, Viasat . Holdings, Amazon and Union Pacific Locations: Boston, Clarivate, London, Qorvo, Amazon

☆ What the Nobel Prizes get wrong about science
▼ + stars: | 2023-09-29 | by ( Katie Hunt | ) edition.cnn.com time to read: +9 min

Peter Brzezinski, the secretary of the committee for the Nobel chemistry prize, said there were no plans to change the rule. He said the Nobel Prize committees, at least for science prizes, are “innately conservative.”DiversityOther criticism leveled at the Nobel Prizes includes the lack of diversity among winners. Of course, these flaws and gaps only matter because the Nobels are far better known than other science prizes, Rees added. The Nobel Prize in physiology or medicine will be announced on Monday, followed by the physics prize on Tuesday and the Nobel Prize in chemistry on Wednesday. The Nobel Prize for literature and the Nobel Peace Prize will be announced on Thursday and Friday, respectively.

Persons: Alfred Nobel, Martin Rees, Rees, ”, Jonathan Nackstrand, Rainer Weiss, Barry Barish, Kip Thorne, David Pendlebury, “ Nobel, ” Pendlebury, Nobel’s, Peter Brzezinski, “, ” Brzezinski, John Jumper, AlphaFold, Lasker, Pendlebury, Emmanuelle Charpentier, Jennifer Doudna, it’s, Carolyn Bertozzi, Andrea Ghez, Naomi Oreskes, Henry Charles Lea, ” Rees Organizations: CNN, Royal Society, Getty, Clarivate’s Institute for Scientific, Nobel Foundation, Academy, Google, Harvard University Locations: Swedish, AFP, Stockholm

To revive its fortunes, the government late last year published its Edinburgh Reforms agenda comprising over 30 proposed changes to existing rules. "There are a variety of factors that keep somewhere attractive in terms of investment, listing and being an international finance centre." "We want the UK to be the world's most innovative and competitive global financial centre," the spokesperson added. CHALLENGING ASSUMPTIONSSupporters of a more vibrant UK stock market are also increasing pressure on bankers managing IPO processes to challenge assumptions about London's poorer liquidity or post-IPO performance, relative to rival venues. Proposed changes to UK listings are encouraging, but may not be enough, said Steve Bates, BIA CEO.

☆ Impactive takes a stake in Clarivate and sets the tone for activism in the post-SPAC world
▼ + stars: | 2023-05-06 | by ( Kenneth Squire | ) www.cnbc.com time to read: +5 min

Business: Clarivate is a global information, analytics and workflow solutions company. Activist Commentary: Impactive Capital is an activist hedge fund founded in 2018 by Lauren Taylor Wolfe and Christian Alejandro Asmar. Impactive Capital is an active ESG (AESG) investor that launched with a $250 million investment from CalSTRS and now has over $2.5 billion. Impactive focuses on positive systemic change to help build more competitive, sustainable businesses for the long run. As with many SPAC companies, there were valuation, corporate governance and compensation incentive concerns at Clarivate.

☆ As earnings season winds down, investors turn to Tuesday's debt ceiling meeting
▼ + stars: | 2023-05-06 | by ( Zev Fima | ) www.cnbc.com time to read: +12 min

With only a small fraction of the S & P 500 left to report quarterly earnings, investors are now turning their focus to another major hurdle for the markets and economy: the debt ceiling crisis. Earlier this week, we looked back to debt limit crisis of 2011 for potential lessons. The protracted fight ultimately ended in an agreement in early August of that year, but it was a choppy summertime ride for investors. Within the portfolio, Wynn Resorts will report Tuesday, after the closing bell, and Disney will report on Wednesday, after the closing bell. Estee Lauder (EL) and Emerson Electric (EMR) reported earnings before the opening bell.

☆ Limiting volatility has driven Clarkston Founders fund to outperform in 2022
▼ + stars: | 2022-12-12 | by ( Alex Harring | ) www.cnbc.com time to read: +4 min

The Clarkston Founders Institutional Fund has always tried to avoid volatility. The Founder's Fund has lost about 2.8% in 2022, notably outperforming other mid-cap value funds, which are down an average 7.2%, and a Morningstar benchmark index, which is lower by 5.6%, all through Dec. 9. As a result, the $610-million fund has a below average beta — a measurement of volatility relative to the broad market — of 0.85, according to Morningstar, versus 1.08 for all mid-cap value funds. The fund ranks in the 15th percentile of all mid-cap value funds in 2022, and is in the 23rd percentile over the past five years. Clarkston's investment policy emphasizes what it calls "quality value" stocks, regarded as high quality and considered undervalued relative to their long-term cash flows.

☆ Elliott raises stake in Pinterest; adds Clarivate, Cardinal Health to portfolio
▼ + stars: | 2022-11-14 | by ( ) www.reuters.com time to read: +1 min

Nov 14 (Reuters) - Hedge fund Elliott Investment Management raised its stake in social media platform Pinterest (PINS.N) while adding Clarivate Plc , Cardinal Health (CAH.N) and Triple Flag Precious Metals Corp (TFPM.TO) to its portfolio, a regulatory filing showed on Monday. The filings are one of the few ways that funds are required to disclose their long positions, but may not reflect current holdings. The filings are closely watched for possible investment trends and potential future performance. Elliott had disclosed a stake in Pinterest in August, citing "significant potential for growth". Rival investment firm Tiger Global Management also added to its stakes in several tech firms in the third quarter, including tech giant Microsoft Corp (MSFT.O), and Jack Dorsey's payments firm Block Inc (SQ.N).

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