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☆ Atlas of cells offers a milestone leap in understanding of the human body
▼ + stars: | 2024-11-21 | by ( Katie Hunt | ) edition.cnn.com time to read: +7 min

New research based on the findings, published in several papers Wednesday in Nature and its sister journals, represents a “leap in understanding of the human body,” according to the Human Cell Atlas consortium. Regev compared scientific knowledge of cell biology before the Human Cell Atlas initiative with a “15th century map.”“Now, years later, the resolution of the map is a lot higher,” she said. The cell atlas aims to fill in a missing link between genes, diseases and treatment therapies. During the Covid-19 pandemic, the Human Cell Atlas community used the available data to reveal that the nose, eyes and mouth were most vulnerable to infection. “It was only clear through the Human Cell Atlas data that those cells were … entry points before the virus continued into the internal organs.

Persons: —, ”, Aviv, Daniel Montoro “, we’ve, Regev, “, Sarah Teichmann, Ken, Blain, Robert Hooke, ” Teichmann, Jeremy Farrar, ” Farrar Organizations: CNN, Human Cell Atlas, Genome, Cell, Google, Human, Human Cell, Cambridge Stem Cell, UK’s University of Cambridge, Wellcome Sanger Institute, Institut, la Vision, HCL, Lyon, World Health Organization Locations: Nature, Genentech, South San Francisco , California, Cambridge, England, Paris, Lyon English

☆ Photo contest reveals strange beauty of the microscopic world
▼ + stars: | 2024-10-17 | by ( Matthew Nighswander | ) www.nbcnews.com time to read: +1 min

Each year, rigorous science and dazzling artistry meet in Nikon's Small World photomicrography competition. Started in 1975, the contest celebrates the beauty of images taken through a light microscope. This year, the competition celebrates its 50th anniversary, and it received about 2,100 photo entries from 80 countries. If sometimes unnerving, the images are always stunning, and this year's contest is no exception. 1st placeThis year's first place prize was awarded to a groundbreaking image of mouse brain tumor cells, taken by Bruno Cisterna, a faculty member at Augusta University's Medical College of Georgia.

Persons: Bruno Cisterna, Lou Gehrig’s Organizations: Augusta University's Medical College of Georgia, Cell Biology Locations: Augusta

☆ Research shows the ages our metabolism undergoes massive rapid changes
▼ + stars: | 2024-08-14 | by ( Linda Carroll | Linda Carroll Is A Regular Health Contributor To Nbc News. She Is Coauthor Of | The Concussion Crisis | ) www.nbcnews.com time to read: +4 min

For many people, reaching their mid-40s may bring unpleasant signs the body isn’t working as well as it once did. Previous research showed that resting energy use, or metabolic rate, didn’t change from ages 20 to 60. The changes in metabolism affect how the body reacts to alcohol or caffeine, although the health consequences aren’t yet clear. For example, the changes in alcohol metabolism might be because people are drinking more in their mid-40s, Snyder said. “But it will take time to sort out what individual changes mean and how we can tailor medications to those changes.

Persons: ”, Michael Snyder, It’s, Snyder, Josef Coresh, Coresh, Lori Zeltser, ” Zeltser Organizations: Stanford, Center for Genomics, Medicine, Stanford Medicine, NYU Grossman School of Medicine, Columbia University Vagelos College of Physicians and Surgeons Locations: midlife

☆ Erythritol: Sweetener in stevia linked to blood clots, study says
▼ + stars: | 2024-08-08 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +7 min

Clots can break off blood vessels and travel to the heart, triggering a heart attack, or to the brain, triggering a stroke. Previous research has linked erythritol to a higher risk of stroke, heart attack and death. Artificially manufactured in massive quantities, erythritol has no lingering aftertaste, doesn’t spike blood sugar and has less of a laxative effect than some other sugar alcohols. That’s especially true for anyone at highest risk for clotting, heart attack and stroke — such as those with existing cardiac disease or diabetes. “Cardiovascular disease builds over time, and heart disease is the leading cause of death globally,” he said.

Persons: erythritol, ”, Stanley Hazen, Hazen, Bleeksma, ” Hazen, Andrew Freeman, “ I’m, Freeman, Carla Saunders, Wai Hong, Wai Hong Wilson Tang, “ Organizations: CNN, Center for Cardiovascular Diagnostics, Cleveland Clinic Lerner Research Institute, Cleveland Clinic, Jewish Health, US Food and Drug Administration, Biology Locations: Denver, United States, Wai Hong Wilson, Europe, America

☆ How to restart exercise after Covid-19, RSV or influenza
▼ + stars: | 2024-03-11 | by ( Melanie Radzicki Mcmanus | ) edition.cnn.com time to read: +5 min

But Covid, RSV and influenza are more serious maladies that require a thoughtful approach to resuming exercise. Turner recommended calculating your maximum heart rate and keeping it below 70% to start, which is considered light exercise. To determine your maximum heart rate, first subtract your age from 220, then calculate 70% of that. For example, a 40-year-old would have a maximum heart rate of 180 beats per minute (220 minus 40). Since 70% of 180 is 126, a 40-year-old’s heart rate should initially stay below 126 beats per minute.

Persons: CNN — You’re, Covid, R.J, Turner, UTHealth, ” Turner, ”, Villano, you’re, don’t, “, you’ll, Melanie Radzicki McManus Organizations: CNN, UTHealth Houston, Biochemistry, Cell Biology, American College of Cardiology, ACC, ” Locations: Hampton Bays , New York

☆ Not so dead as a dodo: ‘De-extinction’ plan to reintroduce bird to Mauritius
▼ + stars: | 2023-12-01 | by ( Tom Page | ) edition.cnn.com time to read: +10 min

CNN —An audacious collaboration between geneticists and conservationists plans to bring back the extinct dodo and reintroduce it to its once-native habitat in Mauritius. But according to the partners, its return to Mauritius could benefit the dodo’s immediate environment and other species. The Nicobar pigeon, native to the coastal regions from the Andaman and Nicobar Islands, is the closest living relative to the dodo. Then it will edit the PGCs of a Nicobar so it expresses the physical traits of a dodo. “I have studied the dodo for many years, and there is still a lot to learn about this enigmatic bird,” he added.

Persons: dodo, Beth Shapiro, ”, Matt James, James, Holger Hollemann, Tatayah, ” Tatayah, “, dodos, Ben Birchall, Julian Hume, ” Hume, Ben Lamm, “ We’re Organizations: CNN, Colossal Biosciences, Mauritian Wildlife Foundation, Getty, Gorges, Colossal, “, White Rhino, Biosciences Locations: Mauritius, Rodrigues Island, Asia, Nicobar, Park, “ Mauritius, Aigrettes, Ile

☆ Scientists create chimeric monkey with two sets of DNA
▼ + stars: | 2023-11-09 | by ( Katie Hunt | ) edition.cnn.com time to read: +7 min

CNN —Scientists based in China have created a monkey chimera with two sets of DNA, experimental work they say could ultimately benefit medical research and the conservation of endangered species. It’s the world’s first live birth of a primate chimera created with stem cells, the researchers said. Scientists have created mouse embryos that are part human, and in 2021, scientists reported that they had grown human-monkey chimeric embryos. In September, researchers reported that they had grown kidneys containing mostly human cells inside pig embryos. Then they selected a subset of cells to inject into genetically distinct 4- to 5-day-old embryos from the same monkey species.

Persons: —, ”, Miguel Esteban, chimeras, Zhen Liu, Liu, Jun Wu, hadn’t, Wu wasn’t, Jacob Hanna, ” Hanna, Penny Hawkins, “ Organizations: CNN —, Cell, Guangzhou Institute of Biomedicine, Chinese Academy of Sciences, Research, University of Texas Southwestern Medical Center, Weizmann Institute of Science, Royal Society for, National Academies of Sciences, Engineering, Medicine, Covid Locations: China, Health, Research Hangzhou, Israel, United States

☆ Lab models of human embryos raise hopes and concerns
▼ + stars: | 2023-10-26 | by ( Katie Hunt | ) edition.cnn.com time to read: +14 min

From the moment sperm fuses with an egg, human embryo development involves a string of complex and little understood processes. What happens during human embryo development, particularly in the crucial first month, remains largely unknown. However, 14 days is an important milestone because it is when permitted lab research on cultured human embryos routinely ends. He said, in the future, it might be possible to go as far as 40 days with human embryo models. Some in the field envision a “tipping point” wherein human embryo models might be afforded some protection like those surrounding human embryos, as scientific advances diminish the differences between the embryo models and their real-life counterparts.

Persons: CNN — It’s, ”, Jacob Hanna, demystify, they’ve, Hanna, “ It’s, ” Hanna, “, Peter Rugg, Gunn, it’s, …, Robin Lovell, Francis Crick, Naomi Moris, Francis Crick Institute’s, Moris, we’ve, ” Moris, It’s, Bobbie Farsides, ” Farsides Organizations: CNN, Weizmann Institute of Science, Weizmann Institute, Israel, Weizmann, Babraham Institute, International Society for Stem Cell Research, Stem Cell, Francis, Francis Crick Institute, Genetics, Development, ”, Sussex Medical School Locations: Israel, London, Brighton

☆ What the Nobel Prizes get wrong about science
▼ + stars: | 2023-09-29 | by ( Katie Hunt | ) edition.cnn.com time to read: +9 min

Peter Brzezinski, the secretary of the committee for the Nobel chemistry prize, said there were no plans to change the rule. He said the Nobel Prize committees, at least for science prizes, are “innately conservative.”DiversityOther criticism leveled at the Nobel Prizes includes the lack of diversity among winners. Of course, these flaws and gaps only matter because the Nobels are far better known than other science prizes, Rees added. The Nobel Prize in physiology or medicine will be announced on Monday, followed by the physics prize on Tuesday and the Nobel Prize in chemistry on Wednesday. The Nobel Prize for literature and the Nobel Peace Prize will be announced on Thursday and Friday, respectively.

Persons: Alfred Nobel, Martin Rees, Rees, ”, Jonathan Nackstrand, Rainer Weiss, Barry Barish, Kip Thorne, David Pendlebury, “ Nobel, ” Pendlebury, Nobel’s, Peter Brzezinski, “, ” Brzezinski, John Jumper, AlphaFold, Lasker, Pendlebury, Emmanuelle Charpentier, Jennifer Doudna, it’s, Carolyn Bertozzi, Andrea Ghez, Naomi Oreskes, Henry Charles Lea, ” Rees Organizations: CNN, Royal Society, Getty, Clarivate’s Institute for Scientific, Nobel Foundation, Academy, Google, Harvard University Locations: Swedish, AFP, Stockholm

☆ Surprising jellyfish finding challenges what’s known about learning and memory
▼ + stars: | 2023-09-22 | by ( Jenna Schnuer | ) edition.cnn.com time to read: +5 min

CNN —Caribbean box jellyfish, animals that may appear to float through life aimlessly and don’t have a central brain, still have the ability to learn rapidly and retain information, new research has found. Caribbean box jellyfish, also known by the scientific name Tripedalia cystophora, have 24 eyes — six in each of four visual sensory centers called rhopalia. How jellyfish learnTo test the animals’ ability to learn, the researchers lined the inside of a round tank with gray and white stripes. The gray stripes would appear to the jellyfish’s 24 eyes as dark as a faraway mangrove root does in their natural habitat. “The scientists devised a very convincing experimental paradigm to quantify associative learning in this box jellyfish.

Persons: Anders Garm, “ We’ve, ”, Jan Bielecki, Bielecki, ” Bielecki, “, Michael Abrams, Abrams, ” Abrams Organizations: CNN, University of Copenhagen, Denmark —, Physiology, Kiel University, University of California, California Institute of Technology Locations: Denmark, Germany, Kiel, Caribbean, Berkeley

☆ In a first, RNA is recovered from extinct Tasmanian tiger
▼ + stars: | 2023-09-19 | by ( Will Dunham | ) www.reuters.com time to read: +4 min

But this study marked the first time that RNA - much less stable than DNA - has been recovered from an extinct species. While not the focus of this research, the ability to extract, sequence and analyze old RNA could boost efforts by other scientists toward recreating extinct species. The Tasmanian tiger resembled a wolf, aside from the tiger-like stripes on its back. The last-known Tasmanian tiger succumbed in a Tasmanian zoo in 1936. Private "de-extinction" initiatives have been launched aimed at resurrecting certain extinct species such as the Tasmanian tiger, dodo or woolly mammoth.

Persons: Emilio Marmol Sanchez, Handout, bioinformatician Emilio Mármol Sánchez, Marc Friedländer, Love, Mármol, Will Dunham, Rosalba O'Brien Organizations: Swedish Museum of, REUTERS Acquire, Tasmanian, Palaeogenetics, Genome Research, Stockholm University, SciLifeLab, Thomson Locations: Stockholm, SciLifeLab, Sweden, Australia, Tasmania, Tasmanian, Washington

☆ A worm has been revived after 46,000 years in the Siberian permafrost
▼ + stars: | 2023-07-28 | by ( Issy Ronald | ) edition.cnn.com time to read: +3 min

CNN —Scientists have revived a worm that was frozen 46,000 years ago — at a time when woolly mammoths, sabre-toothed tigers and giant elks still roamed the Earth. This a major finding,” he said, adding that other organisms previously revived from this state had survived for decades rather than millennia. Five years ago, scientists from the Institute of Physicochemical and Biological Problems in Soil Science in Russia found two roundworm species in the Siberian permafrost. The worm was found in the Siberian permafrost. But still, they didn’t know whether the worm was a known species.

Persons: Teymuras Kurzchalia, Kurzchalia, ”, Anastasia Shatilovich, Panagrolaimus kolymaenis, kolymaenis, —, Philipp Schiffer, Schiffer Organizations: CNN —, elks, Max Planck, Molecular Cell Biology, Institute of Physicochemical, PLOS Genetics, of Zoology, University of Cologne, CNN Locations: Dresden, Science, Russia, Germany, Cologne

☆ Lab-grown breast milk startup Biomilq aims to change infant nutrition — if it can release a product
▼ + stars: | 2023-05-20 | by ( Natasha Piñon | ) www.cnbc.com time to read: +11 min

Biomilq, the company behind the breakthrough, had been working for nearly a decade to replicate the process of making human milk — but outside of the body. While the crisis has highlighted the importance of a resilient formula supply, human milk experts, milk bank advocates and Biomilq all stress the same message: Breast milk is best. The startup will likely take a "gradual approach" to introducing its science via "an early-life nutrition product in partnership with one of these bigger companies," Strickland explained. Breast milk is woefully understudied — to the point that it's difficult "to even say what human milk is from a nutritional standpoint," Perrin explained. The company is researching which aspects of human milk its system is best suited to produce.

☆ Dished up by 3D printers, a new kind of fish to fry
▼ + stars: | 2023-05-03 | by ( ) www.reuters.com time to read: +3 min

An Israeli foodtech company says it has 3D printed the first ever ready-to-cook fish fillet using animal cells cultivated and grown in a laboratory. Israel's Steakholder Foods has now partnered with Singapore-based Umami Meats to make fish fillets without the need to stalk dwindling fish populations. Steakholder Foods then adds them to a 'bio-ink' suited for special 3D printers. It has the flakiness of traditional fish and when fried and seasoned it is hard to tell the difference. "The number of scientists, you can imagine, working on fish stem cell biology is a small fraction of those working on animal cells and human cells."

☆ A drug company abandoned a treatment for ‘bubble boy disease.’ After a 5-year fight, this little girl is about to get it
▼ + stars: | 2023-04-27 | by ( Elizabeth Cohen Lauren Mascarenhas | Elizabeth Cohen | Lauren Mascarenhas | ) edition.cnn.com time to read: +29 min

The Sulacks weighed their options: Have a transplant with a match that was less than ideal – far less – or wait for gene therapy to become available. The news release didn’t say anything else about the SCID gene therapy. Or was the company abandoning its plans for SCID gene therapy altogether? In February, 2021, the parents of more than 20 children who were waiting for the gene therapy treatment, including the Sulacks, wrote a letter to Gaspar. Insurance companies have sometimes balked at paying for gene therapy, which is typically given in one treatment.

☆ Eli Lilly has spent years and billions of dollars in search of an effective Alzheimer's drug. But success is not all or nothing for the stock
▼ + stars: | 2023-01-09 | by ( Kevin Stankiewicz | ) www.cnbc.com time to read: +22 min

Eli Lilly (LLY) has spent decades researching Alzheimer's disease without successfully bringing to market a treatment that slows the memory-destroying condition. For Eli Lilly as a company, an Alzheimer's drug is an important pursuit. Lilly's Alzheimer's history Eli Lilly's "first real foray" into Alzheimer's came in the 1990s, according to Dr. John Sims, Eli Lilly's head of medical development for donanemab. Financial implications for Lilly LLY mountain 2021-10-08 The Club started a new position in Eli Lilly (LLY) in October 2021. The Eli Lilly logo is shown on one of the company's offices in San Diego, California, September 17, 2020.

☆ Ehlers-Danlos syndrome affects millions. Why isn't the medical profession paying more attention?
▼ + stars: | 2022-12-24 | by ( Sarah Lazarus | ) edition.cnn.com time to read: +19 min

“Have you heard of Ehlers-Danlos syndrome?” the podiatrist asked me. There are 13 types of Ehlers-Danlos syndrome (EDS), according to research and advocacy organization The Ehlers-Danlos Society. Drag queen Yvie Oddly, who has hypermobile Ehlers-Danlos syndrome, crab walks down the pink carpet at RuPaul's DragCon LA in 2019. Bluestein says that for many years it was thought that one in 5,000 people had Ehlers-Danlos syndrome. But despite her career choice, Bluestein only received her hEDS diagnosis when she was 47 – more than 30 years later.

☆ Fact Check-New ‘Er’ blood group is not proof COVID-19 vaccines alter DNA
▼ + stars: | 2022-12-16 | by ( Reuters Fact Check | ) www.reuters.com time to read: +3 min

A recently discovered blood group system called Er is not proof that mRNA in COVID-19 vaccines is changing people’s DNA, as some social media users have claimed. Scientists told Reuters that Er has always existed and antigens from the blood group were first discovered more than 40 years ago. New blood group systems have been regularly discovered for decades.”Bailey said: “One of the antigens that make up the blood group system was discovered more than 40 years ago. The existence of the blood group Er does not suggest that mRNA vaccines are changing people’s blood types or DNA. Antigens from the blood group Er were first discovered 40 years ago.

And some members of the general public, too, are squeamish about cell-cultured meat. Caution isn’t necessarily a bad thing, but these critiques of cell-cultured meat are just thinly disguised neophobia — people just feel it is “unnatural.” Cell-cultured meat indeed comes from labs, not farms. To no one’s surprise, cell-cultured meat also faces criticism from some animal rights activists, albeit for a very different reason: because cell cultivation requires starter cells taken from actual animals, cell-cultured meat isn’t completely cruelty-free. And with time, cell-cultured meat may become nutritionally superior to meat from slaughtered animals anyway. No, cell-cultured meat, as we currently know it, isn’t perfect.

☆ Factbox: Winners of 2022 Nobel prizes
▼ + stars: | 2022-10-10 | by ( ) www.reuters.com time to read: +2 min

Nobel Prize for Peace - Jailed Belarusian activist Ales Byalyatski, Russian rights group Memorial and Ukraine's Center for Civil Liberties won the 2022 Nobel Peace Prize amid a war in their region that is the worst conflict in Europe since World War Two. Register now for FREE unlimited access to Reuters.com RegisterNobel Prize for Literature– French author Annie Ernaux won the 2022 Nobel Prize in Literature for "the courage and clinical acuity" in her largely autobiographical books examining personal memory and social inequality. Nobel Prize in Chemistry - Scientists Carolyn Bertozzi, Morten Meldal and Barry Sharpless won the 2022 Nobel Prize in Chemistry for discovering reactions that let molecules snap together to create new compounds and that offer insight into cell biology. Nobel Prize in Physics - Scientists Alain Aspect, John Clauser and Anton Zeilinger won the 2022 Nobel Prize in Physics for experiments in quantum mechanics that laid the groundwork for rapidly-developing new applications in computing and cryptography. Nobel Prize in Physiology or Medicine - Swedish geneticist Svante Paabo won the 2022 Nobel Prize in Physiology or Medicine for discoveries that underpin our understanding of how modern day people evolved from extinct ancestors at the dawn of human history.

☆ В человеческом организме случайно обнаружена новая структура
▼ + stars: | 2021-03-16 | by ( Mld Media Srl | ) noi.md time to read: +2 min

Ученые открыли ранее неизвестную структуру (органеллу) в клетках человека. Кан и его команда случайно обнаружили эту новую структуру, изучая ген под названием DACT1, связанный с ранним развитием костей и раком. Под микроскопом они увидели, что белок DACT1 конденсируется вместе с другими загадочными веществами в нечто похожее на капли масла в воде. Группа Кана обнаружила, что фродосома играет роль во второй фазе распространения опухоли кости. Исследователи обнаружили фродосомы в клетках рака груди и рака простаты, которые метастазировали в кости, но эти структуры также появляются в здоровых клетках человека, включая клетки легких.

Persons: Ибинь Кан, Кан Organizations: Nature Cell, Принстонский университет

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