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☆ A new path to better sleep: Evening exercise breaks
▼ + stars: | 2024-08-23 | by ( Dana Santas | ) edition.cnn.com time to read: +9 min

Now, a small efficacy study published July 16 in the journal BMJ Open Sport & Exercise Medicine suggests a simple yet effective strategy to improve sleep duration: incorporating short resistance, or strength training, exercise breaks in the evening. The findings were compelling: The participants slept an average of 27.7 minutes longer when they took regular exercise breaks compared with when they sat uninterrupted. “Our research found that interrupting evening sitting time with short bursts of light intensity exercise improved sleep duration and did not disrupt sleep quality,” Gale added via email. “Adding quick, simple and light resistance exercise breaks to your evening routine could be a simple way to improve your sleep and health,” he said. Better sleep could be just a few short exercise breaks away.

Persons: Dana Santas, Aaron Lockwood, ”, Jennifer Gale, Gale, ” Gale, Raj Dasgupta, Dasgupta, “ Organizations: Pain, CNN, US Centers for Disease Control, University of Otago, Huntington Health, CNN’s Locations: United States, New Zealand, California

☆ Anti-inflammatory diet cuts dementia risk by nearly one-third, study says
▼ + stars: | 2024-08-13 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +5 min

CNN —Eating an anti-inflammatory diet of whole grains, fruits and vegetables instead of an inflammatory diet focused on red and processed meats and ultraprocessed foods, such as sugary cereals, sodas, fries and ice cream, lowered the risk of dementia by 31%, a new study found. “Following an anti-inflammatory diet was related to lower risk of dementia, even among people with cardiometabolic diseases who are already at elevated risk of dementia,” said Dove, a doctoral student at the Aging Research Center at Karolinska Institutet in Solna, Sweden, in an email. Brain scans of those who followed an anti-inflammatory diet also showed significantly lower levels of brain biomarkers of neurodegeneration and vascular injury, Dove said. carlosgaw/E+/Getty Images/FileWhat is an anti-inflammatory diet? Just a 10% increase in such foods was significantly associated with a 14% higher risk of death from all causes, according to a February 2019 study.

Persons: Abigail Dove, ”, Dove, David Katz, Katz, ” Katz, “ Organizations: CNN, JAMA, Aging Research, Karolinska, True Health Initiative, Mayo Clinic Locations: Solna, Sweden, England, Scotland, Wales

☆ A doctor who says he's reversed his age by 20 years eats these 7 foods every week to boost his longevity
▼ + stars: | 2024-08-13 | by ( Serafina Kenny | ) www.businessinsider.com time to read: +6 min

Read previewA doctor who claims to have reversed his age by 20 years shared the foods he eats weekly in a bid to boost his longevity. Related storiesOlive oilRoizen said he has a tablespoon of olive oil every day. Plus, replacing margarine, butter, mayonnaise, and dairy fats with olive oil appeared to lower the risk of dying by up to 34%. AdvertisementThe authors suggested that this could be because of the anti-inflammatory and antioxidant properties of olive oil, or because people who consumed more olive oil also tended to be more active, less likely to smoke, and ate more fruits and vegetables. CauliflowerRoizen makes a "cauliflower creamer" by blending the vegetable with olive oil and using it as a spread.

Persons: —, Michael Roizen, Roizen, Florence Comite, Caterina Oltean Organizations: Service, Cleveland Clinic, Business, American College of Cardiology, European, of Nutrition, China's Zhejiang University School of Medicine, National Cancer Institute, Penn State University, Lund University, American Heart Association, Centers for Disease Control Locations: Florence, Sweden

☆ Beyond Novo and Eli Lilly: Watch these biotech and weight loss drug names, fund manager says
▼ + stars: | 2024-07-26 | by ( Weizhen Tan | ) www.cnbc.com time to read: +3 min

Weight loss drugs have drawn investor interest and shaken up other sectors in the past year or so. Novo Nordisk and Eli Lilly were two early winners of this trend, as their drugs dominate the weight loss drug market. Yuri Khodjamirian, fund manager at Tema ETFs, said both companies are a "very powerful duopoly." They're a lot more risky than the bigger ones who already have drugs on the market," Khodjamirian said. Tema ETFs offers actively managed exchange-traded funds, with a focus on health care and life sciences.

Persons: Eli Lilly, Yuri Khodjamirian, Goldman Sachs, Khodjamirian, Roche Organizations: Novo Nordisk, Tema, CNBC, Zealand Pharma, Viking Therapeutics, Tema Oncology, Mental Health Locations: Tema

☆ Mediterranean diet found to improve children’s heart health, study finds
▼ + stars: | 2024-07-15 | by ( Taylor Nicioli | ) edition.cnn.com time to read: +6 min

CNN —The Mediterranean diet has been linked to many health benefits for adults. Now, a new study suggests it could be beneficial to children’s heart health as well. Here’s how parents and guardians could help their children benefit from the Mediterranean eating plan, according to experts. The Mediterranean diet is a way of eating that includes plant-based cooking with an emphasis on healthy fats. “The growing research shows the value (in the Mediterranean diet) to be the same for children and adolescents (as in adults),” Muth said.

Persons: ”, José Francisco López, Gil, Stuart Berger, Robert H, Lurie, Berger, Natalie Muth, Muth, Tamara Hannon, Hannon, “, ” Berger, ” Muth Organizations: CNN, JAMA, Health Research, University of, Ann, Lurie Children’s Hospital of Chicago, American Academy of Pediatrics, Care Medical Group, Northwestern University’s Feinberg School of Medicine, Riley Hospital for Children, Indiana University Health, Indiana University School of Medicine Locations: Americas, Quito, Ecuador, San Diego, Chicago, Indianapolis

☆ This ETF is trying to satisfy appetites for weight loss stocks
▼ + stars: | 2024-07-06 | by ( Ellie Stevens | ) www.cnbc.com time to read: 1 min

Tema ETFs has been capitalizing on the risk appetite for weight loss stocks. The firm's founder and CEO Maurits Pot thinks the winning weight loss trade isn't based on just hype. "We could see a world where the majority of the world's population takes a GLP-1, not just for weight loss, but for other diseases." His top holdings include Mounjaro manufacturer Eli Lilly and Ozempic and Wegovy maker Novo Nordisk. Eli Lilly is up 57% so far this year, while Novo Nordisk is up 38%.

Persons: Maurits Pot, Pot, Eli Lilly, Ozempic Organizations: Cardiometabolic, Novo Nordisk Locations: Tema, Novo

☆ ETF Edge, July 1, 2024
▼ + stars: | 2024-07-01 | by ( Bob Pisani | ) www.cnbc.com time to read: 1 min

In this videoShare Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailETF Edge, July 1, 2024Maurits Pot, Tema CEO and founder, joins CNBC's Bob Pisani on 'ETF Edge' to discuss the company's GLP-1, Obesity and Cardiometabolic ETF and American Reshoring ETF. Todd Sohn, Strategas ETF & Technical Strategist, also joins the conversation.

Persons: Maurits Pot, Bob Pisani, Todd Sohn Organizations: Tema, American Reshoring, Technical

☆ Weight loss now its own segment... with its own ETFs?
▼ + stars: | 2024-07-01 | by ( Bob Pisani | ) www.cnbc.com time to read: 1 min

In this videoShare Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailWeight loss now its own segment... with its own ETFs? Maurits Pot, Tema CEO and founder, joins CNBC's Bob Pisani on 'ETF Edge' to discuss the company's GLP-1, Obesity and Cardiometabolic ETF, which invests in weight loss stocks. Todd Sohn, Strategas ETF & Technical Strategist, also joins the conversation.

Persons: Maurits, Bob Pisani, Todd Sohn Organizations: Tema, Technical Locations: Maurits Pot

☆ A successful Alzheimer's drug will help Eli Lilly join the $1 trillion club
▼ + stars: | 2024-06-11 | by ( Kevin Stankiewicz | ) www.cnbc.com time to read: +7 min

Eli Lilly became the most valuable health-care company in the world on the back of its blockbuster diabetes and obesity drugs. The billions of dollars in Eli Lilly is investing in manufacturing capacity support the idea that the long-term opportunity is immense. Adding Eli Lilly to the market could help address some of the obstacles that limited Leqembi's sales early on. Eli Lilly, which has spent billions in search of a successful Alzheimer's treatment , had hoped for donanemab to be approved by now. A sign with the company logo sits outside of the headquarters campus of Eli Lilly and Company on March 17, 2024 in Indianapolis, Indiana.

Persons: Eli Lilly, donanemab, Eli Lilly's, Donanemab, Leqembi —, Biogen, —, Jim Cramer's, Ken Langone, Morgan Stanley, Cantor Fitzgerald, Leqembi, Jim Cramer, Jim, Scott Olson Organizations: Food and Drug Administration, FactSet, Novo Nordisk, FDA, GE Healthcare, CNBC, Company, Getty Locations: GLP, Indianapolis , Indiana

☆ Healthy diets with only 10% ultraprocessed foods may raise risk of cognitive decline, stroke
▼ + stars: | 2024-05-22 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +5 min

All three diets are plant-based, focused on consuming more fruits and vegetables, whole grains, beans and seeds while limiting sugar, red meat and ultraprocessed foods. Eating more ultraprocessed foods such as hot dogs is linked to a higher risk of stroke and cognitive decline, according to a new study. What is it about ultraprocessed foods that may allow them to sabotage efforts to follow a healthy diet? Growing dangers of ultraprocessed foodsStudies on the dangers of eating ultraprocessed foods are piling up. That 10% increase was considered “baseline,” and adding even more ultraprocessed foods might increase the risk, experts say.

Persons: ”, Andrew Freeman, ’ ”, Dr, W, Taylor Kimberly, Kimberly, Peipei Gao, Zhendong Mei, Mei, Gao, Harvard T.H, ’ ” Freeman Organizations: CNN, Jewish Health, Whites, Blacks, Massachusetts General Hospital, Brigham, Women’s Hospital, Harvard, of Public Health Locations: Denver, Massachusetts, Boston, Chan

☆ Your kids’ ultraprocessed food consumption may put them at higher risk, study shows
▼ + stars: | 2024-05-17 | by ( Madeline Holcombe | ) edition.cnn.com time to read: +5 min

CNN —The ultraprocessed foods your kids eat now may be putting them a greater risk for cardiometabolic problems – like heart attack, stroke and diabetes – in adulthood, a new study suggests. Researchers divided the data from the children into three groups based on the amount of ultraprocessed food they ate. “This particular topic, ultraprocessed food consumptions and risk, is a very important topic in kids,” he said. The ultraprocessed foods kids eat now may have lasting impacts, a new study suggests. In places where fresh food might be harder to obtain, ultraprocessed foods are more accessible and inexpensive, Freeman said.

Persons: ”, Stuart Berger, Andrew Freeman, Berger, Robert H, Lurie, Brendan Smialowski, ” Freeman, …, Freeman, there’s Organizations: CNN, American Academy of Pediatrics, Food and Agriculture Organization, United Nations, Jewish Health, Ann, Lurie Children’s Hospital, Getty, BMI Locations: Spain, Denver, Chicago, AFP

☆ Evercore ISI says three years of biotech underperformance may be ending, gives its 5 favorite stocks
▼ + stars: | 2024-05-14 | by ( Hakyung Kim | ) www.cnbc.com time to read: +2 min

"After 3 years of painful underperformance, winter is finally thawing and spring just might be in the air," analyst Cory Kasimov wrote in a Monday note. Biotech stocks broadly peaked in early 2021 when interest rates were at a trough, Kasimov noted. While biotech stocks are sensitive to interest rates, the analyst believes most of the group's other catalysts — such as mergers and access to capital — remain "relatively consistent." XBI YTD mountain SPDR S & P Biotech ETF performance year to date The sector is opportune for investors looking for "a stock picker's market," according to Kasimov. With this in mind, he named seven stocks to his core initial list, which he named "The Magnificent Seven."

Persons: Cory Kasimov, Kasimov, We've, Neurocrine, — CNBC's Michael Bloom Organizations: ISI, Biotech, P Biotech, Moderna Locations: —

☆ Wegovy maker Novo Nordisk down 4%, heads for worst day since October
▼ + stars: | 2024-05-03 | by ( Jenni Reid | ) www.cnbc.com time to read: +1 min

Shares of Danish pharmaceutical giant Novo Nordisk slid 4% on Friday, extending a 2.7% loss on Thursday as analysts pored over the details of the firm's first-quarter results and monitored a potential rival weight loss treatment. The company reported that sales for its blockbuster injectable weight loss treatment Wegovy, more than doubled to 9.38 billion Danish kroner ($1.4 billion). Novo Nordisk, which also makes diabetes treatment Ozempic, said the rise in sales had offset a slight reduction in prices. Analysts expected even higher weight loss drug sales in the quarter, and some noted that Novo Nordisk's 2024 outlook raise for both sales growth and operating profit was due to one-off accounting adjustments. The boom in demand for weight loss treatments saw Novo Nordisk overtake French luxury group LVMH to become Europe's most valuable company last year.

Persons: Karsten Knudsen, Karen Andersen Organizations: Novo Nordisk, Novo, Morningstar Locations: Novo

☆ Weight-loss drug Wegovy offers benefits for people with diabetes and common form of heart failure, study finds
▼ + stars: | 2024-04-06 | by ( Jen Christensen | ) edition.cnn.com time to read: +8 min

The study, published Saturday in the New England Journal of Medicine, showed how the drug helped people with Type 2 diabetes who also had one of the most common kind of heart failure, obesity-related heart failure with preserved ejection fraction. Obesity-related heart failure with preserved ejection fraction can severely limit a person’s ability to participate in the activities of daily life. Often, people with type 2 diabetes who have this kind of heart failure have a more severe form than those who don’t have diabetes. People with a more severe form of heart failure sometimes don’t respond as well to medication as those with less severe disease. One death in the Wegovy group and four in the placebo group were related to cardiovascular issues.

Persons: Wegovy, Ozempic, Dr, Mikhail Kosiborod, “, ” Kosiborod, Naveed Sattar, ” Sattar, Sanjay Gupta, Kosiborod, ” Organizations: CNN, New England, of Medicine, Novo Nordisk –, US Food and Drug Administration, FDA, St, University of Glasgow, Science Media, CNN Health, American College of Cardiology Locations: Asia, Europe, North, South America, Kansas City , Missouri, Atlanta

☆ What’s the best diet for weight loss?
▼ + stars: | 2024-04-06 | by ( Andrea Kane | ) edition.cnn.com time to read: +7 min

We delve into a wide range of topics, including the truth about menopausal weight gain and new weight loss drugs. (CNN) — With dieting, the conventional wisdom says a person needs to be in calorie-deficit mode to lose weight. If you eat more calories than you burn, you gain weight; if you eat fewer calories, you lose weight. — some people will lose weight, and others will gain. Show yourself some compassionAcknowledge it’s not easy to change eating habits to lose weight.

Persons: Sanjay Gupta, ” Christopher Gardner, Farquhar, Gardner, ” Gardner, ”, you’re, “, ‘, Don’t, it’s, Jameela Jamil Organizations: CNN, Stanford University, Stanford Prevention Research, JAMA, Netflix, American Heart Association, American College of Cardiology, Obesity Society

☆ The CEO of a weight-loss ETF that's crushing the S&P 500 since launching in November shares 4 stocks he sees with over 100% upside in the next 12 months
▼ + stars: | 2024-04-04 | by ( William Edwards | ) www.businessinsider.com time to read: +5 min

Weight-loss drugs like Ozempic, Wegovy, and Mounjaro are all the rage, and investors are noticing. Since launching in November, the Tema Obesity and Cardiometabolic ETF (HRTS) is up 24%, crushing the S&P 500's 14.8% returns over the same period. Pot and his colleagues at Tema are bullish on the weight-loss drug stocks due to the wave of demand they see coming. Novo Nordisk estimates that only 2% of obesity cases are being treated by weight-loss drugs, Pot said. 4 weight-loss drug stocks to watchPot listed two larger stocks and two smaller ones in the space.

Persons: Maurits Pot, Janus Henderson, Pot, Goldman Sachs, Geoff Meacham, Charles Barkley, Elon Musk, Whoopi Goldberg, Eli Lilly, Lilly Organizations: VanEck Pharmaceutical, Business, World Health Organization, Novo Nordisk, Bank of America, Bank, Nordisk, FDA, Amazon, Therapeutics, Zealand Pharma Locations: Tema, GLP, Danish, it's

☆ A scientist who studies if supplements work takes 4 daily, to take his health from good to great
▼ + stars: | 2024-03-23 | by ( Kim Schewitz | ) www.businessinsider.com time to read: +5 min

AdvertisementBloomer shared the four supplements that he takes his health from good to great. Fish oilBloomer takes a good quality fish oil every day for heart health and to prevent inflammation, he said. MultivitaminBloomer also takes a good quality multivitamin daily, while acknowledging the body of evidence that suggests they're useless. Protein powderTo ensure he's getting enough protein throughout the day, Bloomer two to three protein shakes a day. "It's relatively inexpensive, and you can get some really good quality proteins these days."

Persons: —, Richard Bloomer, Bloomer, I've, Multivitamin Bloomer, they're Organizations: Service, Center, Nutraceutical, University of Memphis, Business, American Medical Association, Research Locations: Mount Sinai

☆ How sleep can affect diabetes risk, according to new study
▼ + stars: | 2024-03-05 | by ( Kristen Rogers | ) edition.cnn.com time to read: +5 min

Sleep is an important lifestyle factor in reducing risk for type 2 diabetes, a new study has found. In terms of risk for type 2 diabetes, there wasn’t a significant difference between those with normal sleep and those who slept six hours. And even for those who ate the healthiest, their diet didn’t offset the effects of insufficient sleep on diabetes risk. The findings are also based on participants’ recollections of their food and sleep habits, according to the study. Confirming a causal relationship “would require randomized trials intervening on sleeping habits to increase sleep time and see if this reduces risk of diabetes in those at risk, e.g.

Persons: CNN —, Dr, Diana Nôga, ” Nôga, ”, Leana Wen, Wen wasn’t, ” Wen, Naveed Sattar, ” Sattar, Wen Organizations: CNN, JAMA, biosciences, Uppsala University, Lighthouse Films, George Washington University Milken Institute School of Public Health, University of Glasgow Locations: Sweden, United Kingdom, Scotland, “

☆ Ultraprocessed foods linked to 50% higher risk of dying from cardiovascular disease and developing other health conditions
▼ + stars: | 2024-02-28 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +9 min

CNN —Eating ultraprocessed foods raises the risk of developing or dying from dozens of adverse health conditions, according to a new review of 45 meta-analyses on almost 10 million people. All the studies in the review were published in the past three years, and none was funded by companies involved in the production of ultraprocessed foods, the authors said. “People who are having depressive symptoms or anxiety may seek out ultraprocessed foods for various reasons such as self-comfort,” she said. jenifoto/iStockphoto/Getty Images“Two-thirds of the calories children consume in the US are ultraprocessed, while about 60% of adult diets are ultraprocessed,” Zhang said. In addition, it’s nearly impossible to avoid temptation, as over 70% of the US food supply is made of ultraprocessed food.

Persons: ”, Wolfgang Marx, Heinz Freisling, Freisling, “, Melissa Lane, “ It’s, Fang Fang Zhang, Zhang, Mathilde Touvier, Touvier, Carlos Monteiro, Monteiro, ” Monteiro, nutritionists, ” Zhang, it’s, Marx, Lane Organizations: CNN, Centre, Deakin University, Health Organization’s International Agency for Research, Cancer, Deakin, Tufts University, French National Institute of Health, Medical Research, Health, Nutrition, University of São Paulo, NOVA Locations: Geelong, Australia, Boston, Brazil, United States, United Kingdom, Canada

☆ What is the Atlantic diet?
▼ + stars: | 2024-02-13 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +6 min

CNN —The traditional diet of northern Portugal and northwestern Spain, known as the Southern European Traditional Atlantic Diet, or Atlantic diet for short, may hold some clues to better heart health and a lower risk of dying early from cancer, heart disease or any cause, according to studies conducted in Europe. The diet is based on foods grown or found in that part of the Europe, much like its famous cousin the Mediterranean diet. Because it’s plant-based and locally sourced, the Atlantic diet also helps protect the planet by contributing to the United Nations’ Sustainable Development Goals, the study’s authors noted. Like the Mediterranean diet, the Atlantic diet focuses on home-cooked food served family style, with an emphasis on social interactions between friends and family. However, other studies have shown that not all food groups in the traditional Atlantic diet are beneficial.

Persons: ”, Walter Willett, Harvard T.H, David Katz, Al Bochi Organizations: CNN, Southern, JAMA, Harvard, of Public Health, Harvard Medical School, United Nations, True Health Initiative, Atlanta, Academy of Nutrition, “ Locations: Portugal, Spain, Europe, Chan, Boston, Czechia, Poland

☆ Tirzepatide: Weight loss drug helps significantly lower blood pressure in adults who are overweight or obese, study finds
▼ + stars: | 2024-02-05 | by ( Mira Cheng | ) edition.cnn.com time to read: +6 min

The participants had their blood pressure monitored for a day before beginning treatment and again after nine months of weekly tirzepatide injections. The results showed a significant decrease in the participants’ systolic blood pressure, the top number in blood pressure readings, which is a strong predictor of heart disease. It works similarly to semaglutide, the active compound in the weight loss drug Wegovy and its sister diabetes drug, Ozempic. Although there are effective blood pressure medications available, only about a quarter of people with hypertension have adequately controlled blood pressure, Hall said. He views the weight loss effect of the drug as a pleasant side effect that will make people more likely to take their medication.

Persons: —, Eli Lilly, ”, Harlan Krumholz, Michael E, Wegovy, it’s, Ania Jastreboff, Hall, Krumholz, tirzepatide, Dr, Sanjay Gupta, CNN’s Meg Tirrell Organizations: CNN, American Heart Association, Food and Drug Administration, Yale University, Department of Medicine, University of Mississippi Medical Center, Yale Obesity Research Center, CNN Health Locations: United States

☆ Big pharma is at a crossroads, as J&J, Merck and others prepare to lose heaps of revenue from blockbuster drugs
▼ + stars: | 2024-01-28 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +12 min

Bristol Myers Squibb's Eliquis is a blood thinner used to prevent clotting, to reduce the risk of stroke. Bristol Myers Squibb's Opdivo is an immunotherapy used to treat cancers, including melanoma and lung cancer. Investors will get updates on Merck and Bristol Myers Squibb's plans for the years ahead when they report earnings on Thursday and Friday, respectively. That's unlike generics, which are cheaper copycats of small-molecule drugs like Bristol Myers Squibb's Eliquis. Bristol Myers Squibb is also testing a new form of Opdivo, which is currently administered into a patient's veins.

Persons: Johnson, William Blair, Matt Phipps, Bristol Myers, Johnson's, Merck's Keytruda, J's Stelara, Opdivo, Phipps, biosimilars, Eliquis, Biosimilars, Humira, JB Reed, Samsung's, Piper Sandler, Christopher Raymond, AbbVie, Raymond, Chris Schott, Schott, Robert Davis, Keytruda, Davis, JPMorgan's Schott, Bristol Myers Squibb, George Frey, J, Amgen, J confidentially, Mike Perrone, It's, Anna Moneymaker Organizations: New York Stock Exchange, Johnson, NYSE Big, Bristol Myers Squibb, Merck, Biden, William Blair & Company, CNBC, Guggenheim, Bristol, Leerink Partners, Bloomberg, Getty, Bioepis, JPMorgan, JPMorgan Health Care, Moderna, Bristol Myers, Karuna Therapeutics, Hardy, Huntsman Cancer Institute, University of Utah, Reuters, Teva Pharmaceuticals, Pharma, U.S . Department of Health, Human Services Locations: drugmakers, EY, Europe, U.S, Cambridge , Massachusetts, Arda, EY's Americas, Bristol, Salt Lake City , Utah, Washington , DC

☆ Oprah's flip on weight loss drugs is a sign of what's to come for the 'Ozempic trade' in 2024
▼ + stars: | 2023-12-25 | by ( Christina Cheddar Berk | In | ) www.cnbc.com time to read: +10 min

Lilly's Zepbound recently entered the weight loss market, and is off to a strong start. But what's ahead for the weight loss trade in 2024? Beyond weight loss One of 2023's most pivotal events in the space was Novo Nordisk's release of top line results from its Select trial in August . In 2023, the exuberance around weight loss drugs roiled markets in many unexpected ways. The affected companies have also been very vocal in addressing how they plan to coexist with these weight loss products.

Persons: Oprah Winfrey, Eli Lilly, they've, Lilly's, Lilly's Zepbound, Andy Acker, Janus Henderson's, Lilly, Novo, FactSet, Acker, Janus, Buzz, Gregory Renza, Renza, Goldman Sachs, Chris Shibutani, Mike Kratky, Kratky, Dexcom, Leerink, Winfrey, I've, Winfrey's, Michael Bloom Organizations: Novo Nordisk, Wall Street, Wall, RBC Capital, Pfizer, Structure Therapeutics, AstraZeneca, Leerink, Nestle, Oprah Daily, Winfrey, International Locations: Friday's, Eccogene, MedTech, 3Q23

☆ Trial confirms heart benefits of Wegovy, but is weight loss responsible – or something else?
▼ + stars: | 2023-11-11 | by ( Meg Tirrell | ) edition.cnn.com time to read: +9 min

To cardiologist Dr. Steven Nissen of the Cleveland Clinic, who wasn’t involved in the trial but is leading a similar one of tirzepatide, those effects are all evidence of the benefits of weight loss. Tirzepatide has shown greater levels of weight loss than semaglutide in clinical trials, leading many, including Nissen, to hope it will show even stronger cardiovascular benefits. Importantly, participants didn’t have a history of diabetes; a previous trial had shown that treating people with diabetes with a GLP-1 drug, Ozempic, reduced their cardiovascular risk. The Wegovy trial showed that 569 of 8,803 people taking the drug had a heart attack or stroke or died from heart-related causes, or 6.5%. The amount of weight loss seen in the trial, 9.4%, was less than in other studies of Wegovy, which showed average weight loss closer to 15%.

Persons: Ania Jastreboff, Wegovy, Dr, Amit Khera, National Institutes of Health’s Dr, Tiffany M, Powell, Wiley, Eli Lilly, Steven Nissen, wasn’t, ” Nissen, “, Tirzepatide, Nissen, Michael Lincoff, Lincoff, ”, Jastreboff, Sanjay Gupta, hadn’t, “ semaglutide Organizations: CNN, Nordisk’s Wegovy, American Heart Association, Yale Obesity Research Center, University of Texas Southwestern Medical Center Dallas, National Institutes of Health’s, New England, of Medicine, US Food and Drug, Cleveland Clinic, Novo Nordisk, Cleveland, CNN Health Locations: Philadelphia, Powell

The company's research and development (R&D) engine is intact and therefore it is unlikely to do transformative deals soon, Jorgensen said. It was the latest in a series of similarly-sized deals the company has done this year. Last week, when reporting quarterly earnings, it forecast another year of double-digit sales growth for its two most popular drugs: weight-loss drug Wegovy and diabetes Ozempic. To keep up with demand, Novo is racing to increase production of those drugs, which contain the same active pharmaceutical ingredient, semaglutide, and are delivered in self-injection pens. A healthcare banker, speaking on condition of anonymity, told Reuters after the interview there were many companies in the cardiometabolic space with early-stage drugs that Novo Nordisk may be able to buy.

Persons: Lars Fruergaard Jorgensen, Wegovy, Jorgensen, Novo, Novo's, Jacob Gronholt, Maggie Fick, Terje Solsvik, Emelia, Barbara Lewis Organizations: Novo, Novo Nordisk, Reuters, KBP Biosciences, Nordisk, Pedersen, Thomson Locations: Novo, COPENHAGEN, Singapore, Copenhagen, London

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