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Chin-Hong said the variant is a so-called recombinant of two other strains — KS.1.1 and KP.3.3 — meaning that genetic information was exchanged between them to form a third strain, XEC, Chin-Hong said. Is the XEC variant more contagious? Chan School of Public Health, said there’s no evidence yet that the XEC variant is much more transmissible than what’s currently circulating. The variant is closely related to KP.2, the strain targeted by the updated vaccines from Pfizer and Moderna. Bright, however, cautioned that clinical data is ultimately needed to determine how well the updated vaccines work against the XEC variant.

Persons: “, ”, Peter Chin, ” XEC, we’re, Rick Bright, Hong, Bill Hanage, ” Hanage, It’s, XEC, Hanage, “ It’s, Marc Johnson, Johnson, There’s, ” Chin, ” Johnson, ” Bright Organizations: Centers for Disease Control, Prevention, University of California, Biomedical, Research, Development Authority, Department of Health, Human Services, CDC, Harvard, of Public Health, University of Missouri School of Medicine, Pfizer, Moderna Locations: United States, San Francisco, Europe, Chin, U.S, Chan, Germany, Netherlands, France

☆ Why 4 new bird flu developments have experts worried about the virus
▼ + stars: | 2024-06-12 | by ( Morgan Mcfall-Johnsen | ) www.businessinsider.com time to read: +9 min

Read previewBird flu is flying wild, and it has many infectious disease experts more worried now than ever. The H5N1 avian influenza virus has killed tens of millions of birds across the planet and more than 40,000 sea lions and seals. Most people seem to have very little chance, if any, of catching H5N1 avian influenza right now. Jim Vondruska/ReutersBut infectious disease experts are increasingly concerned that the H5N1 virus could make a sustained jump into humans and start spreading among us. This virus is a leading candidate for the next pandemic, and four developments in the past month have experts worried.

Persons: —, Jim Vondruska, That's, Dr, Monica Gandhi, Bird, WHO —, Christopher Dye, Dye, David L, Ryan, Gandhi, Tayfun, Rick Bright, Cynthia Goldsmith, Jackie Katz, Richard Webby, Jude, Talita, Lima Freitas, Amanda Perobelli, Marko Geber, Terry Chea, they've Organizations: Service, CDC, Business, Global Medicine, University of California, Health Organization, WHO, University of Oxford, Boston Globe, Getty, US Department of Agriculture, Anadolu Agency, The Telegraph, Biomedical, Research, Development Authority, AP, Centre, Studies, Reference Laboratory, World Organization for Animal Health, Vaccines, University of Pennsylvania Locations: Luz, Monee , Illinois, San Francisco, Australia, Kolkata, India, New Mexico, New York, St, Michigan, Campinas, Brazil

☆ Bird flu is rampant in animals. Humans ignore it at our own peril
▼ + stars: | 2024-06-11 | by ( Brenda Goodman | ) edition.cnn.com time to read: +15 min

Then, three healthy ferrets were placed in the same enclosures with three of the sick animals. These animals could touch, nose and lick the sick animals, and all of them became ill.Next, the CDC tested airborne transmission by putting three healthy ferrets into an enclosure where they could breathe the same air as sick animals but couldn’t touch them. In her lab, ferrets with previous exposures to seasonal flu strains didn’t get as sick when exposed to new flu viruses compared to those with no prior exposure to seasonal strains. How much help we might get from past exposures to flu viruses is difficult to predict, however, which is why vaccination would still be important to tune up our immunity. They never spread the virus to any of the other animals in the facility — including themselves.

Persons: Mark Naniot, Naniot, “, ”, It’s, Jeremy Farrar, Jesse Bloom, Fred Hutch, ” Naniot, Naniot hadn’t, Scott Weese, Weese, there’s, Covid, Rick Bright, Sanjay Gupta, Bright, Erin Sorrell, Zahl, Seema Lakdawala, hasn’t, ” Bright, Dr, Richard Webby, Jude Children’s, “ It’s, Ducks, Michael Osterholm, “ I’ve, he’s Organizations: CNN, Swiss Army, World Health Organization, Fred Hutch Cancer Center, University of Guelph, US Centers for Disease Control, CDC, Research, Development Authority, CNN Chief, Bright Global Health, Johns Hopkins Center for Health Security, Getty, Emory University, STAT, Administration, Strategic Preparedness, USDA, Jude Children’s Research, Infectious Disease, University of Minnesota, CNN Health Locations: Wisconsin’s, United States, Seattle, Canada, Texas, Vadso, Finnmark, Norway, AFP, Finland, St, Wisconsin

☆ ICON to partner with US govt agency to test COVID vaccine candidates
▼ + stars: | 2023-09-13 | by ( ) www.reuters.com time to read: +1 min

Vials labelled "VACCINE Coronavirus COVID-19" and a syringe are seen in front of a displayed U.S. flag in this illustration taken December 11, 2021. REUTERS/Dado Ruvic/Illustration/File Photo Acquire Licensing RightsCompanies Icon Plc FollowBioNTech SE FollowModerna Inc Follow Show more companiesSept 13 (Reuters) - Contract research firm ICON Plc (ICLR.O) said on Wednesday it is partnering with the U.S. government for a clinical trial to test the effectiveness of next generation COVID-19 vaccine candidates. As part of the collaboration with Biomedical Advanced Research and Development Authority, ICON will conduct a mid-stage trial of 10,000 participants to assess the efficacy of a next generation COVID-19 vaccine relative to currently available shots. The U.S. agency will select the vaccine candidate for the trial. The U.S. Food and Drug Administration on Monday authorized updated COVID-19 vaccines from Pfizer (PFE.N)/BioNTech (22UAy.DE) and Moderna (MRNA.O) that target the XBB.1.5 subvariant of the virus.

Persons: Dado Ruvic, Pratik Jain, Saumyadeb Chakrabarty, Shounak Organizations: REUTERS, U.S, Research, Development Authority, U.S . Food, Drug Administration, Pfizer, Moderna, Thomson Locations: U.S, Bengaluru

☆ Venture Capital Investors Are Trying to Take Over Pandemic Response
▼ + stars: | 2023-03-12 | by ( Adam Rogers | ) www.businessinsider.com time to read: +19 min

Private capital has been eyeing public health for years. Several founders and investors told me that the failure of Kleiner's fund made Silicon Valley wary of investing in pandemic preparedness. Venture investors love that kind of thing. Public health and private industryWhen COVID hit, Charity Dean was the assistant director of the California Department of Public Health. In the end, almost every pandemic-related product created by Silicon Valley will ultimately require the government as a primary customer.

☆ Flu experts gather with H5N1 risk on the agenda
▼ + stars: | 2023-02-24 | by ( Jennifer Rigby | ) www.reuters.com time to read: +3 min

But it is also a chance to discuss the risk of animal viruses spilling over to humans and causing a pandemic. At this week's meeting, H5N1 clade 2.3.4.4b was a key topic, the World Health Organization (WHO) and global flu experts told Reuters. They will brief reporters on both the seasonal flu vaccine composition and spillover risks later on Friday. "We need to really continue the efforts for a flu pandemic." A number of companies that produce seasonal flu vaccines can also make pandemic flu vaccines.

The subvariant of omicron, named XBB.1.5, has raised concerns about another potential wave of Covid cases following the busy holiday travel season. The CDC projected Friday that about 40% of confirmed U.S. Covid cases are caused by the XBB.1.5 strain, up from 20% a week ago. There’s no indication it causes more severe illness than any other omicron virus, Dr. Barbara Mahon, director of CDC’s Coronavirus and Other Respiratory Viruses Division, told NBC News. The XBB.1.5 is a relative of the omicron XBB variant, which is a recombinant of the omicron BA.2.10.1 and BA.2.75 subvariants. Yet, only 37.5% of that age group has received the most recent omicron booster, according to the most recent CDC data.

☆ U.S. sends experimental antibody, antiviral drug to Uganda for Ebola outbreak
▼ + stars: | 2022-10-18 | by ( Julie Steenhuysen | Nancy Lapid | ) www.reuters.com time to read: +3 min

There are currently no proven vaccines or treatments for the Sudan species of Ebola, one of four known Ebola viruses to cause hemorrhagic fever in humans. The outbreak confirmed by the Ugandan health ministry on Sept. 20 is the largest of the Sudan species since 2000. "If healthcare workers start to fall ill and die, it's going to negatively impact the response," said Montgomery, who had just returned from a trip to Uganda. For instance, healthcare workers may be reluctant to assist in the response, he said in a phone interview. A large outbreak of the Zaire species of Ebola in West Africa from 2014-2016 led to effective vaccines and treatment, but there are no proven treatments or vaccines for the Sudan species.

☆ Moderna a început să îşi testeze vaccinul anti-COVID-19 pe adolescenţi
▼ + stars: | 2020-12-10 | by ( Publika.Md - Aici Sunt Știrile | ) www.publika.md time to read: +2 min

Compania americană Moderna a anunţat joi că a inoculat primii participanţi la un studiu clinic de fază 2 şi 3 ce vizează testarea vaccinului său anti-COVID-19 pe adolescenţi cu vârste cuprinse între 12 şi 18 ani, ale cărui rezultate sunt aşteptate înainte de începerea anului şcolar 2021-2022, informează Reuters.Studiul va fi realizat pe un grup de 3.000 de participanţi sănătoşi din Statele Unite şi va analiza siguranţa şi eficienţa vaccinului Moderna, mRNA-1273, care este administrat în două doze, la un interval de 28 de zile.Alianţa Pfizer-BioNTech a depus la rândul ei cereri de aprobare în regim de urgenţă de către autorităţile cu rol de reglementare din Statele Unite şi din Uniunea Europeană, după ce vaccinul său, administrat tot în două doze, a dovedit o eficienţă de 95% în prevenirea maladiei COVID-19 şi nu a generat îngrijorări legate de siguranţă.Membrii unui comitet extern de experţi, care consiliază Administraţia pentru alimente şi medicamente (FDA) din Statele Unite, se vor reuni joi, 10 decembrie, pentru a se pronunţa dacă vor recomanda sau nu folosirea vaccinului Pfizer pe persoane cu vârste de peste 16 ani.O întrunire similară a consilierilor FDA este programată în data de 17 decembrie pentru discuţii legate de vaccinul Moderna.Studiul companiei Moderna ce vizează grupe de adolescenţi este realizat în colaborare cu Biomedical Advanced Research and Development Authority, parte din Departamentul pentru Sănătate din Statele Unite. "Obiectivul nostru este să obţinem datele acestui studiu în primăvara anului 2021, pentru a permite utilizarea vaccinului mRNA-1273 pe adolescenţi înainte de începerea anului şcolar din 2021", a declarat CEO-ul companiei americane, Stephane Bancel.De asemenea, grupul Pfizer îşi testează vaccinul propriu în această perioadă pe adolescenţi cu vârste cuprinse între 12 şi 18 ani, scrie digi24.ro.

Persons: Reuters.Studiul, Stephane, îşi Organizations: americană Moderna, Uniunea Europeană, FDA, Moderna, Biomedical Advanced Research, Development Locations: Statele Unite, Moderna

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