The 24-year-old Greek trailed by two sets to one after twice Wimbledon champion Murray edged ahead in three tight sets on Thursday night before Wimbledon's curfew halted play mid-battle.
Errors began to come from his racket and Tsitsipas sensed his moment with a break in the third game -- the first time he had taken Murray's serve in the match.
Tsitsipas forged 5-3 ahead but Murray hung in to test the Greek's nerve.
Two match points went begging but at the third time of asking an ace ended Murray's dream.
It was a very difficult game and I'm impressed how well he holds up after his hip surgeries and his level today," Tsitsipas said.
Persons:
Britain’s Andy Murray, Andrew Couldridge, Stefanos Tsitsipas, Andy Murray, Murray, Tsitsipas, Murray's, Austrian Dominic Thiem, Laslo Djere, Andy, I'm, Martyn Herman, Ken Ferris, Ed Osmond
Organizations:
Lawn Tennis, Croquet Club, Court, Wimbledon, Murray, Austrian, Thomson
Locations:
London, Britain