What is peptic ulcer disease? Around 5 to 10 percent of the general global population will develop peptic ulcers at some point in their lives, but many patients are asymptomatic. What causes peptic ulcer disease? A bacteria called Helicobacter pylori is a major cause of peptic ulcer disease cases. Another common cause of peptic ulcers is medications known as nonsteroidal anti-inflammatory drugs, like those that bring down a fever or relieve joint pain — think aspirin, naproxen and ibuprofen.

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Persons: Scott Gabbard, Harold J, Boutte, Gabbard, It’s, Amy Oxentenko, Mark Pochapin Organizations: Cleveland Clinic, Northwestern Medicine, Mayo Clinic, gastroenterology, NYU Langone Health