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Novo Nordisk on Wednesday reported third quarter earnings broadly in line with expectations and narrowed its 2024 full-year growth guidance. The Danish pharmaceutical giant said that its net profit in the third quarter hit 27.3 billion Danish kroner ($3.92 billion), above an LSEG aggregate estimate of 26.95 billion Danish kroner. EBIT — earnings before tax and income — came to 33.8 billion Danish kroner, also just above the LSEG forecast of 33.51 billion Danish kroner. The guidance reflected the company's expectations for sales growth in North America and internationally, which is largely driven by volume growth of treatments based on Glucagon-like peptide-1 (GLP-1), Novo Nordisk said. Novo Nordisk added that it was investing in capacity both internally and externally to increase supply in the short- and long-term.
Persons: , — CNBC's Annika Kim Constantino Organizations: Novo Nordisk, Wednesday, Novo, Nordisk, U.S . Food, Drug Administration Locations: Danish, North America, Novo, U.S
The only approved treatments for Alzheimer’s disease are medications with limited effectiveness and a risk of severe, sometimes deadly, side effects. Researchers found that when the device was aimed at the right spot in the brain, it could slow the development of symptoms, such as memory loss, compared to an inactive treatment. In Alzheimer’s, nerve cells in the brain at some point start to dysfunction, leading to the debilitating symptoms of memory loss. What’s more, during the yearlong TMS trial, participants receiving the experimental treatment showed little decline in their abilities to perform the activities of daily living. Sinaptica’s weekly brain stimulation therapy is intended to strengthen connections in areas of the brain that control memory.
Persons: Giacomo Koch, ” Koch, Koch, Irina Skylar, Scott, , , Lawrence Honig, Honig, Ryan Darby, Darby Organizations: University of Ferrara, Sinaptica, NBC News, TMS, Alzheimer’s Association, Food and Drug Administration, Stanford University’s Center, Memory Disorders, Columbia University Irving Medical Center, Vanderbilt University Medical Center Locations: Madrid, Cambridge , Massachusetts, U.S
Here are the biggest calls on Wall Street on Thursday: Goldman Sachs reiterates Microsoft as buy Goldman says the stock remains extremely attractive following earnings on Wednesday. Bank of America reiterates as Meta as buy Meta remains a "top AI pick" following earnings on Wednesday. Deutsche Bank downgrades Kraft Heinz to hold from buy Deutsche says it sees "reduced growth" following earnings. BTIG upgrades Wingstop to buy from neutral BTIG said investors should buy the dip following earnings on Wednesday. "We are upgrading shares of Wingstop to Buy from Neutral with a $370 price target following the post-earnings selloff in shares yesterday."
Persons: Goldman Sachs, Goldman, Al, Oppenheimer, Wolfe, Bernstein, it's, JPMorgan downgrades Brinker, Morgan Stanley downgrades Biogen, Morgan Stanley, Deutsche Bank downgrades Kraft Heinz, KBW, Wells, Wells Fargo, L3Harris Organizations: Microsoft, Bank of America, Meta, JPMorgan, Chili's, Corp, Deutsche Bank, Deutsche, Walmart, Technologies, of America Locations: Robinhood, 4Q24, OW
In my mid-20s, my mom started losing her memory, which made me feel isolated. My fiancé and I are planning our wedding as fast as we so she can be part of our wedding. My mom began losing her memoryThen, in my mid-20s, something else started to differentiate me once again from my peers. My dad, who barely has a memory of life without my mom. On my right wrist is a tattoo of a Chai necklace my dad gave me, which his father gave him.
Persons: , grandpa, bubbled, I'm Organizations: Service, Alzheimer's Association
A test tube is seen in front of displayed Biogen logo in this illustration taken on, December 1, 2021. Biogen on Wednesday reported third-quarter revenue and adjusted earnings that topped expectations while raising its full-year profit guidance, as sales of its breakthrough Alzheimer's drug, Leqembi, and other new products gain traction. Leqembi, which Biogen shares with the Japanese drugmaker Eisai, became the second drug proven to slow the progression of Alzheimer's to win approval in the U.S. last summer. The drug posted just $10 million in sales last year following its launch. That compares with a net loss of $68.1 million, or 47 cents per share, for the same period a year ago.
Persons: Biogen, StreetAccount Organizations: U.S, Wall Street, LSEG Locations: U.S
The report was messy, but it doesn't dim Eli Lilly's bright multiyear outlook, rendering the dip in the stock as a chance to buy. LLY .SPX 5Y mountain Eli Lilly's five-year stock performance compared with the S & P 500. Bottom line We're upgrading Eli Lilly to our buy-equivalent 1 rating and leaving our price target of $1,000 a share unchanged. Eli Lilly Why we own it: Eli Lilly's best-in-class drugs should enable growth above the industry average for many years to come. Eli Lilly's new Alzheimer's drug Kisunla, which was approved by the FDA in July, was not a major focus on the call.
Persons: Eli Lilly, Eli, Eli Lilly's, Jim Cramer, Jim, , that's, David Ricks, Ricks, Semaglutide, Wegovy, Lilly, There's, Mounjaro, Trulicity, Verzenio, Jim Cramer's, Cristina Arias Organizations: Revenue, The Club, CNBC, JPMorgan, Novo Nordisk, Food, Novo Nordisk's, FDA, Zepbound, Biogen, Merck, Pfizer, Morphic, Company, Pharmaceutical Locations: Tuesday's, U.S, Novo, Eisai, FactSet, Zepbound, Alcobendas, Madrid, Spain
Organic revenue growth of 1% matched expectations. Management raised the midpoint of full-year earnings guidance despite the continued in weakness in China that has been hampering top-line organic growth. Bottom Line Results were mixed, but it comes as no surprise that the quarter was negatively impacted by weakness in China. The team continues to deliver for customers and we've seen PDx reports seven quarters of high-single-digit or double-digit organic revenue growth." Pharmaceutical Diagnostics (PDx) segment — used in radiology and nuclear medicine to deliver more precise diagnoses — was particularly strong, delivering segment revenue growth of 7% organically.
Persons: Peter Arduini, Arduini, We're, James Saccaro, Saccaro, GEHC, Jim Cramer's, Jim Cramer, Jim, Martin Schutt Organizations: GE Healthcare, Revenue, LSEG, Management, Pharmaceutical Diagnostics, General Electric, Philips, Siemens, U.S . Food, Drug Administration, GE Healthcare's, Care Solutions, CNBC, Getty Locations: China, U.S, Jena , Germany
Revenue from obesity treatment Zepbound is forecast to climb to $1.73 billion from $1.24 billion quarter over quarter. For the year, analysts expect Mounjaro sales to reach $4.58 billion, while Zepbound revenue is seen rising to $5.88 billion. The consensus view for combined sales of both drugs now stands at $30.19 billion, according to FactSet. Other key announcements A clinical trial is in progress that pits Zepbound against Novo Nordisk's Wegovy in obesity treatment. Beyond obesity, Lilly has begun treating patients with Kisunla, its Alzheimer's disease treatment.
Persons: Eli Lilly, Lilly, Seamus Fernandez, Morgan Stanley, Terence Flynn, David Risinger, Morgan Stanley's Flynn, Mounjaro, Cantor, Louise Chen, , Fred Imbert Organizations: Investment, Food, Leerink, Novo Nordisk's, FDA, Kisunla Locations: U.S
Find out the impact of the US healthcare system and the health of Americans to our costs and lifespans. In this episode of "Just the Facts," Health and Healthcare. In 2022, 3.28 million Americans died, about 1% of our total population; nearly 3.67 million people were born. As of 2023, 6.7 million Americans over age 65 had been diagnosed with it. Of the $4 1/2 trillion dollars in health spending, 3.7 trillion was spent on personal healthcare, while 760 billion was spent on things like public health, health research, healthcare facilities, medical equipment, and the cost of running health insurance programs.
Persons: Steve Ballmer, USAFacts, COVID Organizations: Insider, LA Clippers, Healthcare, FBI, Medicare, Affordable, Health Locations: America, COVID, Alzheimer's, United States
Veronica Shanklin left her top marketing job to care for her grandmother with dementia in May 2013. My grandmother, then 82, who I called "Mama Nell," had become aggressive and physically lashed out at my mom. They'd shared a home in my native Dallas since Mama Nell was diagnosed with Alzheimer's Disease a few years earlier. I've established a nonprofit to help dementia carers like meMama Nell died in 2017 at the age of 86. In 2019, I founded the nonprofit Dementia Care Warriors to help Texan caregivers of loved ones with Alzheimer's and related diseases.
Persons: Veronica Shanklin, , Mama Nell, They'd, Mom, Veronica Shanklin I'd, I've, it's Organizations: Service, PBS, Business, Business Administration, Arts Management, Shanklin, Dementia, Warriors Locations: Dallas, Chicago, Atlanta, California
Julia Hawkins, a centenarian runner, died at 108 in Baton Rouge, Louisiana. AdvertisementJulia Hawkins, a record-setting centenarian runner who picked up the sport after she turned 100, died on Tuesday in Baton Rouge, Louisiana. Here are her five tips for living a long life. Stay activeHawkins credits her long life and good health to an active lifestyle. Even before she picked up running, Hawkins was already competing in the Senior Olympics as a cyclist, she said.
Persons: Julia Hawkins, Hawkins, , It's, Guideposts, I've, Brit Huckabay, I'm, they're, Fabrizio Villatoro, Murray Hawkins Organizations: Service, Louisiana Senior Olympic Games, New York Times, Olympics, National Senior Games, Washington Post, Louisiana State University, Times, Harvard Locations: Baton Rouge , Louisiana
Novo Nordisk 's blockbuster diabetes drug Ozempic may reduce the risk of developing Alzheimer's disease, suggesting its potential to delay or prevent the memory-robbing condition, according to a study released Thursday. Alzheimer's disease is often diagnosed in the mild dementia stage, when a person has significant trouble with memory and thinking. But the number of Alzheimer's patients is projected to rise to almost 13 million in the U.S. by 2050. Novo Nordisk, which did not fund the new Case Western study, is also examining semaglutide in a late-stage study on Alzheimer's patients. In the liraglutide research, data from a midstage trial found that the drug may slow the progression of Alzheimer's disease by protecting patients' brains.
Persons: Semaglutide, Dr, Rong Xu, it's, Xu, Eli Lilly, Wegovy, Eli Lilly's Organizations: Novo Nordisk, Alzheimer's Association, Case Western Reserve University, CNBC, Nordisk, Case, National Institutes of Health, GLP Locations: U.S, Novo
Each year, rigorous science and dazzling artistry meet in Nikon's Small World photomicrography competition. Started in 1975, the contest celebrates the beauty of images taken through a light microscope. This year, the competition celebrates its 50th anniversary, and it received about 2,100 photo entries from 80 countries. If sometimes unnerving, the images are always stunning, and this year's contest is no exception. 1st placeThis year's first place prize was awarded to a groundbreaking image of mouse brain tumor cells, taken by Bruno Cisterna, a faculty member at Augusta University's Medical College of Georgia.
Persons: Bruno Cisterna, Lou Gehrig’s Organizations: Augusta University's Medical College of Georgia, Cell Biology Locations: Augusta
Here's a rapid-fire update on all the stocks in Jim Cramer's Charitable Trust, the portfolio we use for the CNBC Investing Club. Broadcom: Of course, we love the company's AI business — both its custom silicon solutions for companies such as Alphabet and its networking chips that help stitch data centers together. Stanley Black & Decker: Jim said that this stock is the "most significant beneficiary" from lower rates in the entire portfolio. As a subscriber to the CNBC Investing Club with Jim Cramer, you will receive a trade alert before Jim makes a trade. Jim waits 45 minutes after sending a trade alert before buying or selling a stock in his charitable trust's portfolio.
Persons: Jim Cramer's, Jim, there's, Lisa Su, Wells, Salesforce, CrowdStrike, it's, we've, Walt Disney, , Eaton, we're, Kamala Harris, Harris, Jim's, Linde, Eli Lilly, Lilly isn't, That's, Morgan Stanley, Goldman Sachs, D.A, Satya Nadella's, Palo, cybersecurity, Brian Niccol, We're, Stanley Black, Decker, TJX, Charlie Scharf, Wells Fargo's, Jim Cramer, Angela Weiss Organizations: Jim Cramer's Charitable Trust, CNBC, Club, Apple Intelligence, Abbott Laboratories, Devices, AMD, Nvidia, Broadcom, Apple, Federal Reserve, Costco Wholesale, Costco, Coterra, DuPont, Disney, ESPN, GE Healthcare, Democratic, Biden, Honeywell, Linde, Adobe, Microsoft, Davidson, Palo Alto Networks, Constellation Brands, Modelo, Corona, TJX, Jim Cramer's Charitable, New York Stock Exchange, AFP, Getty Locations: Wells Fargo, BlackRock, Dover, Eaton, China, U.S, Chipotle, New York City
Stock Chart Icon Stock chart icon Cassava Sciences' year-to-date stock performance. Cassava Sciences : "They do have an Alzheimer's trial, but Lilly has an Alzheimer's formulation that is very good. And Lilly does have the edge on everybody else." Stock Chart Icon Stock chart icon Mobileye Global's year-to-date stock performance. Mobileye Global : "...I think it's just too hard to tell, I'm going to stay away from it."
Persons: Lilly, Mobileye Organizations: Mobileye
Eli Lilly will spend $4.5 billion to build a center aimed at finding better ways to manufacture its medicines. The facility, called the Lilly Medicine Foundry, will house development of new manufacturing methods with an eye toward efficiency. It's a strategy that's already paying off with Lilly's obesity and weight loss drugs Mounjaro and Zepbound, and Lilly wants it to propel the rest of its pipeline. Lilly says the facility will be the first of its kind to combine research and production in a single location. It will be near a $9 billion manufacturing complex Lilly is building in Lebanon, Indiana, to produce pharmaceutical ingredients like tirzepatide, the active ingredient in Mounjaro and Zepbound.
Persons: Eli Lilly, Mounjaro, Lilly, David Ricks, , Dan Skovronsky Organizations: Lilly, Foundry, Indianapolis, Novo Nordisk's Ozempic Locations: Indianapolis, Lebanon , Indiana, tirzepatide
Here are JPMorgan's top stock picks heading into October
  + stars: | 2024-10-02 | by ( Sean Conlon | ) www.cnbc.com   time to read: +4 min
For October, the additions include Best Buy and Carmax , while Wayfair , CarGurus and First Citizens BancShares are among those removed. The bank cited positive existing home sales, and an expansion in AI adoption, believing Best Buy will see continued growth in average selling prices . Analyst Christopher Horvers says Best Buy will increase its profitability over time, noting an uptick in operating margins to 5% from last year's 4.1%. He has an overweight rating on the stock, and his price target of $111 implies more than 9% upside from Tuesday's close. The bank's price target for Schwab implied about 22% upside and for Ulta Beauty about 18% potential appreciation, based on Tuesday's close.
Persons: JPMorgan's, Christopher Horvers, BBY, Eli Lilly, Lilly, Charles Schwab, Schwab Organizations: JPMorgan, Nasdaq, Dow Jones, Wall, AT, TPG Locations: Israel, Richland , Minnesota, Dallas, DirectTV, Lilly, Ireland
Wall Street currently sees GE Healthcare earning $6.72 per share in 2028, according to FactSet, up from $4.25 projected this year. GE Healthcare has been a stock we've been battling since its steep slide during the second quarter. That dynamic — coupled with the positive China stimulus announcements in recent days — turned GE Healthcare into one of our top-performing stocks in the third quarter . A PET scan using Flyrcado has better diagnostic efficacy than SPECT scans, according to GE Healthcare. GE Healthcare may also see a recovery in its China business due to the roll out of medical-focused stimulus spending .
Persons: Wells, Flyrcado —, Wells Fargo, Flyrcado, FactSet, Jim Cramer, , Jim, Leqembi, Eli Lilly, Stifel, Jim Cramer's, Yi Haifei Organizations: GE Healthcare, GE, Food and Drug Administration, Wall, FDA, Federal, Club, CDC, Management, CNBC, Fair for Trade, Services, China National Convention Center, China News Service, Getty Locations: China, U.S, Beijing
The table and chart below illustrate some characteristics of the biopharma stocks. The average price/earnings multiple for the group, using 2025 estimates, is 12.7 times versus 20.6 times for the S & P 500. A major knock on the biopharma group is the limited productivity from their extremely expensive research efforts, other than obesity drugs, over the past twenty-five years. The technology using AI might not be ready yet, particularly related to the complex biology of the human body. Complex programs exist already, such as AlphaFold, which predicts the structure of three-dimensional compounds using data on protein sequences.
Persons: Bristol Myers, Amgen, Eli Lilly, Lilly, Johnson Organizations: CNBC, Merck, Pfizer, Novo Nordisk, JPMorgan Locations: Bristol
That came after short-seller Hindenburg Research revealed last month it had taken a short position in the company, citing "fresh evidence of accounting manipulation." Cassava Sciences — The biotech company fell 11% after agreeing to pay $40 million to settle a case with the Securities and Exchange Commission. Wynn Resorts — The stock rose about 6% thanks to an upgrade to overweight from equal weight at Morgan Stanley. Amgen — The biotech's shares rose 2% after Cantor Fitzgerald initiated research coverage with an overweight rating. — The aerospace and defense stock added 16% following a price target increase from KeyBanc Capital Markets, which retained an overweight investment rating.
Persons: Bristol Myers, Hindenburg, Morgan Stanley, Amgen, Cantor Fitzgerald, Olivia Brayer, Michael Leshock, — CNBC's Sean Conlon, Alex Harring, Yun Li, Hakyung Kim, Samantha Subin, Pia Singh Organizations: Bristol Myers Squibb, Food and Drug Administration, Bristol, Nordisk —, JPMorgan, Wall, Costco Wholesale, Revenue, Wall Street Journal, Justice Department, Hindenburg Research, Securities and Exchange Commission, Wynn Resorts, UAE, HP Inc, Bank of America, KeyBanc Locations: Nordisk — U.S, Danish, Las Vegas
Costco Wholesale — The membership-only retailer saw shares dip about 1% after the company missed expectations for fiscal fourth-quarter revenue. Super Micro Computer — Shares of the artificial intelligence beneficiary slipped 2%, adding to their 12% loss in the previous session. The Wall Street Journal reported that the U.S. Justice Department had opened a probe on the company. Dollar General — Shares fell 2% after Citi downgraded Dollar General to sell from neutral, saying Walmart 's increasing dominance in retail, especially on pricing, has the dollar store "on the wrong side." HP Inc. — The tech hardware stock fell about 2% after a downgrade to neutral from buy at Bank of America.
Persons: Myers Squibb, Costco, Hindenburg, Morgan Stanley, , KeyBanc, — CNBC's Hakyung Kim, Lisa Kailai Han, Yun Li, Sarah Min, Jesse Pound, Samantha Subin, Michelle Fox Organizations: Myers, U.S . Food, Drug Administration, Novo Nordisk —, JPMorgan, Costco Wholesale, Revenue, Street Journal, U.S . Justice Department, U.S . Securities, Exchange Commission, Wynn Resorts, Citi, Walmart, HP Inc, Bank of America, HP Locations: Bristol, U.S, Novo Nordisk — U.S, Danish
Corcoran's mother, Florence, was diagnosed with Alzheimer's in her late 60s. About eight months ago, Corcoran finally saw a doctor to evaluate her own risk for dementia. There, Corcoran loved watching the systems at Florence created to keep the home and the children organized. Advertisement"I was admiring her with the systems," Corcoran said. Corcoran paid one of her sisters — who lived nearest Florence — to quit her job and become their mother's caretaker.
Persons: Alzheimer's, Corcoran, , Barbara Corcoran, Florence —, Florence, It's, I, Corcoran's, she's, You've, Cocoran Organizations: Service Locations: Florence, Edgewater , New Jersey, Brooklyn
China related stocks were on the move Tuesday after the People's Bank of China said it will cut interest rates. What the Jefferies downgrade misses is the market is giving Starbucks a pass as Niccol builds his team and makes changes. Truist downgraded Club holding Costco to a hold rating ahead of earnings, which are out after Thursday's close. The analysts still have a hold-equivalent rating on Club holding Home Depot but boosted their price target to $400 per share. China related stocks were on the move Tuesday after the People's Bank of China said it will cut interest rates.
Persons: Brian Niccol, Chipotle, Jefferies, Truist, Salesforce, Piper Sandler, Oppenheimer, Regeneron, Eli Lilly, Pinterest, , Jeff Marks, Jim Cramer's, Jim Cramer, Jim Organizations: People's Bank of, Starbucks, Jefferies, Costco, Walmart, Analysts, Barclays, Constellation Brands, Oppenheimer, Justice Department, Visa, Bloomberg, Jim Cramer's Charitable, CNBC Locations: China, People's Bank of China, Japan
As global growth continues to slow, investors should get overweight on defensive names, according to UBS. August marked yet another month of declining global growth, as the Global Manufacturing Purchasing Managers' Index (PMI) reported 49.5 for the month , down from 49.7 in July, according to S & P Global Market Intelligence. Wall Street has taken a bullish stance, as 12 of the 18 analysts covering the stock have issued strong buy or buy ratings, according to LSEG. Constellation Energy has also been on a monster run this year, with shares surging 70%. About 82% of the analysts covering the stock rate it a buy or strong buy, according to LSEG.
Persons: Dow Jones, Eli Lilly, it's Organizations: UBS, Global Manufacturing, P Global Market Intelligence, Institute for Supply Management, Federal Reserve, Constellation Energy, Constellation Locations: Ireland
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailWatch CNBC's full interview with Sandbox AQ CEO Jack Hidary and Breyer Capital's Jim BreyerJack Hidary, Sandbox AQ CEO, and Jim Breyer, Breyer Capital founder, joins 'Money Movers' to discuss how Sandbox AQ is using its technology to cure the Alzheimer's disease, why Breyer is so excited about LQMs, and much more.
Persons: Jack Hidary, Breyer Capital's Jim Breyer Jack Hidary, Jim Breyer, Breyer Organizations: AQ, Breyer Capital
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