DIRS.INFO The most relevant business & tech news

☆ Top 45 MLB free agents for 2024-25 with contract predictions, team fits: Will Soto get $600M+?
▼ + stars: | 2024-10-24 | by ( Jim Bowden | ) www.nytimes.com time to read: +48 min

MLB free agency is almost here so it’s time for my annual ranking of the top free agents with contract predictions and the best team fits for each player. Best team fits: Dodgers, Yankees, Mets, Diamondbacks, Red SoxSalary comps: NoneContract prediction: Minor-league contract4. Several teams have early interest in Walker, with the Astros and Mariners being the best early team fits. Best team fits: Padres, Rangers, Dodgers, Orioles, Guardians, MetsSalary comps: N/AContract prediction: None at this time19. Best team fits: Yankees, Mariners, Diamondbacks, BrewersSalary comps: Anthony Rizzo (2 years, $40M); Josh Bell (2 years, $33M)Contract prediction: 1 year, $15 million42.

Persons: Juan Soto, Corbin Burnes, Blake Snell, Max Fried, Roki Sasaki, Pete Alonso, Anthony Santander, Christian Walker, Alex Bregman, I’ve, He’s, Aaron Judge, Bobby Witt Jr, Soto, Mike Trout, Mookie Betts, Cy Young, Burnes, Stephen Strasburg, Jacob deGrom, Aaron Nola, Roki, Sasaki, he’s, Gerrit Cole, Cole, Cole won’t, Will, Brett Davis, They’ll, Carlos Rodón, Patrick Corbin, Tyler Glasnow, Pete, Matt Olson, Nolan Arenado, Kris Bryant, Carlos Correa, George Springer, Matt Chapman, Nolan Arenado’s, Dana Brown, Xander Bogaerts, Snell, —, José Berríos, Sonny Gray, Freddy Peralta, Peralta, Anthony, Shohei Ohtani, Tommy Gilligan, Brandon Nimmo, Willy Adames, Corey Seager, Andrew Friedman, Adames, Dansby Swanson, Javier Báez, Trevor Story, Marcell Ozuna, Ozuna, Walker, Paul Goldschmidt, Anthony Rizzo, Cody Bellinger, Cody Bellinger didn’t, Bellinger, Nick Castellanos, Kyle Schwarber, Shane Bieber, Tommy John, Bieber, Sean Manaea, Brad Penner, Manaea, Hyun Jin Ryu, Eduardo Rodriguez, Chris Bassitt, Miles Mikolas, Jack Flaherty, Flaherty, NL Cy Young, Lance McCullers Jr, Mitch Keller, Pablo López, Kyle Hendricks, Tomoyuki Sugano, Sugano, Michael Wacha, Jameson Taillon, Jon Gray, Nathan Eovaldi, Seth Lugo, Teoscar Hernández, Jayne Kamin, Teoscar, Hernández, Starling Marte, Jorge Soler, Walker Buehler, Buehler, Tanner Scott, Raisel Iglesias, Robert Suarez, Jurickson, Profar, Mitch Haniger, Lourdes Gurriel Jr, Michael Conforto, Eugenio Suárez, Suárez, Chris Taylor, Max Muncy, Jordan Montgomery, Wasserman, Ken Kendrick, Montgomery doesn’t, Seong Kim, Mike Shildt, Kim, J.P, Crawford, Jeff McNeil, Nico Hoerner, Orlando Arcia, Gleyber Torres, Torres, Tyler O’Neill, Bob DeChiara, Cody Bellinger —, O’Neill, Andrew Benintendi, Ian Happ, Yusei Kikuchi, Kikuchi, Tyler Anderson, Brandon Lowe, Lowe, Brandon Drury, Jorge Polanco, Nick Martinez, Martinez, Charlie Morton, Frankie Montas, Joc Pederson, Rhys Hoskins, Mitch Garver, Justin Turner, Charlie Blackmon, Carlos Estévez, Gregory Fisher, Estévez, Dave Dombrowski, Jeff Hoffman, Kendall Graveman, José Alvarado, Joe Jiménez, Ryan Pressly, Taylor Rogers, Luis Severino, Zach Eflin, Lucas Gioloto, Marcus Stroman, Reynaldo López, Jose Quintana, Tyler Mahle, Blake Treinen, Emilio Pagán, Wandy Peralta, Alex Verdugo, Mark Canha, Manuel Margot, Hunter Renfroe, Jose Iglesias, Chris Sale, Iglesias, Isiah Kiner, Miguel Rojas, Goldschmidt, Josh Bell, Hoskins, Hoffman, Matt Strahm, Chris Martin, Matthew Boyd, Boyd, Lance Lynn, Kyle Gibson, Clay Holmes, Luke Weaver, Dan Goldfarb, Mary DeCicco, Daniel Shirey Organizations: MLB, eventual, The Athletic, Baseball, OF, Boras, Yankees, American League, New York, Blue Jays, Dodgers, Phillies, Rangers, Nationals, Mets, Orioles, Red Sox, Chiba Lotte Marines, NPB, Diamondbacks, Angels, Kansas City, Braves, FIP, Star, Mariners, Astros, Giants, Rockies, Cardinals, Cy Young, Brewers, Milwaukee, Anthony Santander, RF, Santander, Reds, Adames, Rays, Cubs, Pirates, Cy, Guardians, Padres, Tigers, NL Cy, Twins, Yomiuri Giants, of Famers, Royals, Excel, Marlins, NL, The Diamondbacks, Montgomery, Sox, Tampa Bay, White Sox, Atlanta, Talent Sports, Apex, Athletics, Getty Locations: Bronx, Japan, New York, Houston, Walker, Seattle, Bledsoe, Tampa, Philadelphia, Fiume

☆ Dak Prescott is the highest-paid player in NFL history. Here are the 10 highest-paid players in the league this season.
▼ + stars: | 2024-09-11 | by ( Mykenna Maniece | ) www.businessinsider.com time to read: +1 min

Dallas Cowboys quarterback and 2023 NFL MVP runner-up Dak Prescott has the highest-paying contract in the NFL, with an AAV of $60 million. Dallas Cowboys quarterback Dak Prescott is the highest-paid player in NFL history. Nick Cammett/Stringer/Getty ImagesAnd finally, just hours before the first football Sunday of the 2024 season, the Dallas Cowboys announced that they were extending Prescott's contract in a four-year, $240 million deal, making him the highest-paid player in NFL history. Per the Cowboys, he told reporters after the game, "I hope after today we're done talking about it and my pockets. Prior to his history-making deal, Prescott told reporters on Thursday, September 5, that what motivates him is winning, not the money.

Persons: Dak Prescott, Nick Cammett, Stringer, Prescott, he's, —, hasn't Organizations: Dallas Cowboys, NFL, The Cowboys, Cleveland Browns, Cowboys Locations: Dallas

☆ US Marines debuted a new amphibious combat vehicle, which was previously pulled out of the water after multiple rollovers
▼ + stars: | 2024-05-08 | by ( Drew F. Lawrence | ) www.businessinsider.com time to read: +4 min

The US Marines' new amphibious combat vehicle made its first overseas deployment in the Philippines. AdvertisementThe Marine Corps ' new amphibious combat vehicle, or ACV, debuted in the Philippines as part of its first overseas deployment after more than a year-and-a-half of limited operations. AdvertisementA US Marine Corps amphibious combat vehicle splashes off the amphibious dock landing ship USS Harpers Ferry (LSD 49) during Exercise Balikatan 24 in Palawan, Philippines. AdvertisementUS Marine Corps amphibious combat vehicles conduct a towing exercise during Exercise Balikatan 24 in Palawan, Philippines. That vehicle, called the amphibious assault vehicle, or AAV, had been used since the 1970s.

Persons: —, ACVs, Col, Sean Dynan, Lance Cpl, Peyton Kahle, Matthew Bylski, Chris Mahoney, Boxer, Military.com Organizations: US Marines, Service, Corps, Marines, Pacific, 15th Marine Expeditionary Unit, Marine Corps, US Marine Corps, . Locations: Philippines, Philippine, South, Camp Pendleton , California, Palawan, Oyster Bay, USS Somerset, San Diego

☆ Take a ride inside Ehang's fully autonomous, two-seater air taxi
▼ + stars: | 2024-04-18 | by ( Arjun Kharpal | Cristy Garratt | ) www.cnbc.com time to read: +1 min

About an hour's drive from the company's headquarters in Guangzhou, China, sits a test site for Ehang's autonomous aerial vehicles. Perched on the tarmac during CNBC's visit was the company's fully autonomous, two-seater air taxi. Its scheduling system runs on the server, so its route is automatically loaded, and then it carries out a completely automated route flight." Because of this other aircraft, we also need to build a vertical take-off and landing flight site between cities," Wang said. Take a tour of the EH216 and watch its test flight by clicking the video above.

Persons: Dong Wang, Ehang, AAV, Wang Organizations: CNBC Tech, Civil Aviation Administration, Federal Aviation Administration Locations: Guangzhou, China, United States

☆ China gives Ehang the first industry approval for fully autonomous, passenger-carrying air taxis
▼ + stars: | 2023-10-13 | by ( Evelyn Cheng | ) www.cnbc.com time to read: +1 min

An EHang all-electric Vertical Takeoff and Landing (eVTOL) two-passenger multicopter aircraft, performs an unmanned display flight at a Korean government event at Yeouido island in Seoul on November 11, 2020. BEIJING — Self-driving air taxis are one step closer to reality in China. Guangzhou-based Ehang on Friday said it received an airworthiness "type certificate" from the Civil Aviation Administration of China for its fully autonomous drone, the EH216-S AAV, that carries two human passengers. The regulator is the equivalent of the Federal Aviation Administration in the U.S.U.S.-listed Ehang claims it's the first in the world to get such a certificate, which allows it to fly passenger-carrying autonomous electric vertical take-off and landing (eVTOL) aircraft in China. Ehang shares have nearly doubled in price this year, before trading was temporarily halted Monday "in anticipation of an upcoming announcement concerning a very significant development regarding its business operations."

Persons: it's, Huazhi Hu, Ehang Organizations: BEIJING —, Civil Aviation Administration, China, Federal Aviation Administration, U.S ., CNBC Locations: Seoul, BEIJING, China, Guangzhou, U.S . U.S, U.S, Europe, Southeast Asia

☆ NASA's supersonic passenger flights are getting closer
▼ + stars: | 2023-08-25 | by ( Julia Buckley | ) edition.cnn.com time to read: +3 min

Since the 2003 end of Concorde, of course, flitting quickly across the Atlantic has been a thing of the past. Flights between London and New York take around eight hours, or closer to seven in the other direction. But now, the thought of supersonic travel has been mooted again – by none other than NASA, which reckons that New York-London flight could take as little as 90 minutes in the future. However, NASA is developing “quiet” supersonic aircraft, called X-59s, as part of its Quesst mission. Lockheed MartinSimilar studies to the ones done now, which were carried out a decade ago, shaped the development of the X-59 aircraft, according to Lori Ozoroski, project manager for NASA’s Commercial Supersonic Technology Project.

Persons: flitting, NASA’s, Lockheed Martin, Lori Ozoroski, ”, Mary Jo Long, Davis Organizations: CNN, Concorde, NASA, NASA’s Glenn Research Center, Atlantic, Air Vehicles, Boeing, Northrop Grumman Aeronautics Systems, Lockheed, NASA’s, Technology Locations: London, New York

☆ AstraZeneca to buy Pfizer's rare disease gene therapy portfolio for up to $1 bln
▼ + stars: | 2023-07-28 | by ( ) www.reuters.com time to read: +1 min

[1/2] FILE PHOTO-Test tubes are seen in front of a displayed AstraZeneca logo in this illustration taken, May 21, 2021. REUTERS/Dado Ruvic/Illustration/File PhotoJuly 28 (Reuters) - AstraZeneca (AZN.L) said on Friday its unit Alexion has agreed to buy U.S. drugmaker Pfizer's <PFE.N> early-stage rare disease gene therapy portfolio for up to $1 billion, plus royalties on sales. AstraZeneca bought Alexion in 2021. It focuses on rare diseases and plans to close the deal in the third quarter, the British drugmaker said. AAV capsids have been shown to be an effective mechanism for delivering therapeutic gene cargos for gene therapy and gene editing, the company said.

Persons: Dado Ruvic, Alexion, drugmaker, AAV, Yadarisa, Nivedita Organizations: AstraZeneca, REUTERS, Thomson Locations: Bengaluru

☆ China's tech sector may see fewer regulatory surprises — not zero, says S&P Global Ratings
▼ + stars: | 2023-05-24 | by ( Sheila Chiang | ) www.cnbc.com time to read: +2 min

SHANGHAI, CHINA - MAY 10: A visitor takes photos of Ehang 216 electrical vertical take-off and landing (VTOL) autonomous aerial vehicle (AAV) during the Exposition on China Brand 2023 at the Shanghai World Expo Exhibition and Convention Center on May 10, 2023 in Shanghai, China. But the scope for surprises should be significantly diminished and they shouldn't result in significant operational challenges, as occurred in 2021," said S&P Global Ratings, in a report. "China's internet sector has emerged from its regulatory shakeup. Policymakers are signaling support and seem done with big legal changes or sweeping actions," said the report entitled "China's internet regulations: Fewer surprises, not zero surprises." China's crackdown on its large tech companies started in 2020, which saw the government imposing new regulations on tech.

☆ Morgan Stanley sees this gene therapy stock doubling from here
▼ + stars: | 2023-02-01 | by ( Alex Harring | ) www.cnbc.com time to read: +2 min

Rocket Pharmaceuticals could soar as a trial with blockbuster sales potential enters a pivotal phase, according to Morgan Stanley. Analyst Michael Ulz initiated the stock at overweight with a $45 price target. That target share price implies the stock will rally 107.1% from Tuesday's close. Ulz called Rocket a "leading gene therapy company" that can find the best treatments for a given disease. RP-A501, a one-time gene therapy treatment, has shown "promising" phase one results among adults and children, Ulz said.

☆ Thai AirAsia readies personnel as China travel resumes
▼ + stars: | 2023-01-20 | by ( ) www.reuters.com time to read: +1 min

[1/2] A flight attendant participates in an annual aviation safety & emergency course as China reopens its borders, at Asia Aviation Academy in Bangkok, Thailand January 19, 2023. REUTERS/Chalinee ThirasupaBANGKOK, Jan 20 (Reuters) - Budget carrier Thai AirAsia (AAV.BK) is preparing its pilots and cabin crew for the return of Chinese tourists, previously its largest customer group, as the airline resumes routes across China. The airline plans to restart flights to eight Chinese cities including Chongqing, Guangzhou, Hangzhou, and Wuhan, for which cabin crew are undergoing refresher training courses. "In the flight, we should have at least one cabin crew who can speak Mandarin to communicate with passengers," said cabin crew member, Sakuna Puangpipat. Reporting by Napat Wesshasartar; Writing by Chayut Setboonsarng; Editing by Kanupriya KapoorOur Standards: The Thomson Reuters Trust Principles.

☆ Health-care stocks are looking good for 2023 and not just because the sector is a 'safe haven'
▼ + stars: | 2022-12-21 | by ( Christina Cheddar Berk | ) www.cnbc.com time to read: +9 min

Investors looking for cover this year would have done well if they sought a safe haven in large-cap pharmaceutical stocks, a trend that is likely to continue into 2023. The Inflation Reduction Act provided some clarity around drug pricing that should help health-care stocks. The average price target, according to FactSet, is $62, or nearly 40% above the stock's closing price on Tuesday. Gene therapies in focus Investors will be closely watching the progress of several gene therapies, according to Phipps. "Yes, these are expensive therapies," Phipps said.

☆ Five countries, other than China, most dependent on the South China Sea
▼ + stars: | 2022-11-18 | by ( Sean M. Holt | ) www.cnbc.com time to read: +11 min

Territorially, there are seven claimants to the South China Sea: China, Brunei, Indonesia, Malaysia, the Philippines, Taiwan and Vietnam. Analysts name the top five countries, other than China, that are most dependent on the South China Sea. Aerial view of fishing boats setting sail to South China Sea for fishing on August 16, 2022 in Yangjiang, Guangdong Province of China. "Although they claim more than half of the South China Sea, China has pushed claimant states such as Vietnam out of traditional fishing waters and more into the South China Sea, causing excessive overfishing." South KoreaSouth Korea is "intentionally quiet about the South China Sea" as it wants to "maintain favor with China," Graham said, citing Seoul's primary focus on the North Korean issue.

Last month, it unveiled plans to spin off its Canadian oil sands assets into a new publicly traded company, which surprised many industry watchers. McCrea expects the recent trend of takeovers of private Canadian oil companies by larger companies to continue rather than the IPO route. The last time a new Canadian energy listing appeared on the TSX was in January when Calgary-based Kiwetinohk Energy Corp (KEC.TO) shares started trading. read moreNow, energy stocks have become a refuge for investors facing a sell-off in high growth sectors. Some energy investors welcomed the idea of more Canadian oil and gas listings.

☆ Ученые разрабатывают назальный спрей против коронавируса COVID-19
▼ + stars: | 2020-12-03 | by ( Mld Media Srl | ) noi.md time to read: +2 min

Ученые из Пенсильванского университета и биотехнологическая фирма Regeneron изучают, можно ли использовать технологию, разработанную для генной терапии, для изготовления назального спрея, который предотвратит заражение новым коронавирусом, передает medikforum-ru.turbopages.org. «Преимущество нашего подхода в том, что для его эффективности не нужна компетентная иммунная система», - сказал AFP Джеймс Уилсон, профессор медицины в Пенсильвании, возглавляющий проект. В феврале правительство США связывалось с Уилсоном, чтобы узнать, могут ли он и его лаборатория использовать эту технологию против COVID-19. Исследователи надеются, что назальный спрей может быть впрыснут через ноздри, проникнет в эпителиальные клетки носа и захватит их белковые механизмы, чтобы они вырабатывали антитела к Регенерону. AAV вызывают лишь умеренный иммунный ответ, поэтому побочные эффекты могут быть менее серьезными, чем у передовых вакцин, которые работают, обучая иммунную систему распознавать ключевой белок вируса.

Persons: Джеймс Уилсон, Уилсон, Регенерон, Дональд Трамп Organizations: AFP, Пенсильванский университет Locations: Пенсильвания, США

☆ Oamenii de știință americani lucrează la un spray nazal împotriva COVID-19
▼ + stars: | 2020-12-02 | by ( Publika.Md - Aici Sunt Știrile | ) www.publika.md time to read: +5 min

Oamenii de știință de la Universitatea din Pennsylvania și firma de biotehnologie Regeneron investighează dacă tehnologia dezvoltată pentru terapia genică poate fi utilizată pentru a produce un spray nazal care va preveni infecția cu noul coronavirus. Wilson a fost contactat de guvernul SUA în februarie pentru a vedea dacă el și laboratorul său ar putea folosi tehnologia împotriva COVID-19. Deoarece coronavirusul intră în plămâni prin pasajul nazal, spray-ul ar putea opri infecția în urmele sale. Amintim că Universitatea din Birmingham (UK) a anunțat că a dezvoltat un spray nazal care protejează împotriva coronavirusului și îi împiedică transmisia. În același timp, dacă o persoană care a folosit spray-ul strănută sau tușește, scade riscul ca particule active de COVID-19 să ajungă în căile respiratorii ale altei persoane, explică oamenii de știință.

Persons: James Wilson, Penn, Wilson, american Donald Trump ., Regeneron, Liam Grover Organizations: Universitatea din, Universitatea Locations: Universitatea din Pennsylvania, SUA, american, Pennsylvania, Universitatea din Birmingham, UK

Search resuls for: "AAV"

15 mentions found