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Worms get the munchies, too, study reveals
  + stars: | 2023-04-20 | by ( Katie Hunt | ) edition.cnn.com   time to read: +4 min
It turned out the worms did respond, and cannabinoids made them hungrier for their favored foods and less hungry for their non-favored food. The research ultimately revealed that the worms, like humans, engage in hedonic feeding — a phenomenon more commonly known as the munchies. Fluorescent wormsBy measuring the swallowing rate of the worms, Lockery and his team determined that the cannabinoids were increasing how much of a particular bacteria blend the worms ate, making them hungrier. At the molecular level, the cannabinoid system in these worms looks a lot like that in people and other animals. Despite having a small number of neurons (302 neurons versus 86 billion neurons in humans), the worms have a nervous system that includes a primitive brain.
35 Ways Real People Are Using A.I. Right Now
  + stars: | 2023-04-14 | by ( Francesca Paris | Larry Buchanan | ) www.nytimes.com   time to read: +24 min
People are using ChatGPT and other A.I. Here’s how 35 real people are using A.I for work, life, play and procrastination. People are using A.I to …Plan gardens. Chris Norn Researcher at the University of Washington Two years ago researchers cracked the code on using A.I. When you run a Dungeons & Dragons game, Mr. Green says, you have to be creative, but that almost always means pulling from existing fantasy literature.
When we've been awake for a long time, our sleep drive kicks in and tells us we need to sleep. During REM sleep, the cortex – responsible for cognition and emotion-processing – is activated in some regions and deactivated in others. After cycling through non-REM and REM sleep around 4 to 5 times, the basal forebrain and other structures receive signals to start exiting sleep. WHEN SLEEP GOES WRONGIn the U.S. alone, 50 to 70 million people experience some type of chronic sleep disorder, according to the American Academy of Sleep Medicine (AASM). In the United States, a list of board-certified sleep medicine physicians and accredited sleep disorders centers is available from the American Academy of Sleep Medicine.
Researchers on Friday said they had analyzed the genomes of 23 woolly mammoths - including 16 newly sequenced ones - based on remains preserved in Siberian permafrost. "We find that woolly mammoths had molecular adaptations in genes related to coping with cold Arctic environments, such as thick fur, fat storage and metabolism, and thermal sensation, among others," Díez-del-Molino added. Woolly mammoths were about the size of modern African elephants, around 13 feet (4 meters) tall, but had much smaller ears to guard against losing body heat from a larger ear surface. One of them in humans is associated with Uncombable Hair Syndrome, a condition characterized by dry and frizzy hair that cannot be combed flat. The study helped clarify variable shades of mammoth hair color - brownish with a touch of red.
Why fighting the urge to sleep may be bad for our health
  + stars: | 2023-04-07 | by ( ) www.reuters.com   time to read: +17 min
What happens when we sleep Sleep itself has cycles, in which the brain and body move through phases, marked by varying brain activity. Moving into REM sleep A region in the upper brainstem kickstarts the move into REM sleep. Waking up After cycling through non-REM and REM sleep around 4 to 5 times, the basal forebrain and other structures receive signals to start exiting sleep. Then we transition back to lighter sleep, into REM sleep and back down again, and so on until we wake up. Tips for better sleep Good sleep habits can contribute to better sleep, studies have found.
Graphene oxide is not an ingredient in the vaccine,” she said. When contacted by Reuters, a Pfizer spokesperson sent a link with the full list of ingredients of the Pfizer-BioNTech COVID-19 vaccine (here, see page six). No graphene oxide is listed. “We confirm that graphene oxide is not used in the manufacture of the Pfizer-BioNTech COVID-19 vaccine,” the spokesperson said. The Pfizer COVID-19 vaccine does not contain graphene oxide.
Getty ImagesResearch has been exploring how the eye may help in diagnosing Alzheimer’s disease before symptoms begin. “Alzheimer’s disease begins in the brain decades before the first symptoms of memory loss,” said Dr. Richard Isaacson, an Alzheimer’s preventive neurologist who is also at the Institute for Neurodegenerative Diseases. Researchers then compared samples from donors with normal cognitive function to those with mild cognitive impairment and those with later-stage Alzheimer’s disease. The study, published in February in the journal Acta Neuropathologica, found significant increases in beta-amyloid, a key marker of Alzheimer’s disease, in people with both Alzheimer’s and early cognitive decline. Tissue atrophy and inflammation in cells in the far periphery of the retina were most predictive of cognitive status, the study found.
China approves its first mRNA Covid-19 vaccine
  + stars: | 2023-03-23 | by ( Juliana Liu | ) edition.cnn.com   time to read: +1 min
Hong Kong CNN —China has approved its first Covid-19 vaccine based on mRNA technology, months after the country lifted strict pandemic measures. The vaccine targets the Omicron variant and was tested in China with over 5,500 people, it added. “This is a positive step because there is strong scientific evidence that mRNA vaccines do much better than non-MRA vaccines,” Jin Dong-yan, a professor in molecular virology at the University of Hong Kong, told CNN. Until now, China has approved only inactivated vaccines made by Sinovac Biotech and Sinopharm Group, two Beijing-based drugmakers. The inactivated vaccines have been found to elicit lower levels of antibody response compared to ones using the newer messenger RNA technology.
Members of the AlphaFold team in front of the European Molecular Biology Laboratory in Heidelberg, Germany. AlphaFold was trained on public data resources, including those managed by the EMBL’s European Bioinformatics Institute. Meta Platforms Inc.’s new tool predicting the structure of hundreds of millions of proteins is the latest example of a breakthrough in computational biology that began several years ago at an Alphabet Inc. subsidiary. Some scientists expect the new class of artificial-intelligence systems to accelerate work in the life sciences, particularly drug development.
The World Health Organization on Friday called on China to release new data linking the Covid pandemic's origins to animal samples at Wuhan Market after the country recently took down the research. Researchers from several countries downloaded and analyzed the data before it was removed, and presented their findings to the WHO last weekend. But she said it does establish that animals who can carry Covid were sold at the market, which is "new information." The WHO is pushing for studies to be conducted in other markets in Wuhan and across China, according to Van Kerkhove. She added that the WHO "won't be able to remove different hypotheses" until China reuploads its data.
Factbox: Global firms with exposure to collapsed SVB
  + stars: | 2023-03-13 | by ( ) www.reuters.com   time to read: +7 min
March 13 (Reuters) - Startup-focused lender SVB Financial Group (SIVB.O) became the largest bank to fail since the 2008 financial crisis last week, sending shockwaves across global markets as billions of dollars belonging to companies and investors were left stranded. The collapse raised concerns that the end of decades-long era of cheap money would reveal cracks in the global financial system as climbing interest rates expose vulnerabilities in the economy. HSBC (HSBA.L) said on Monday it is acquiring the UK subsidiary of SVB for 1 pound, rescuing a key lender for technology start-ups in Britain. Below is a list of companies across the globe that have revealed their exposure to SVB:EUROPEAround 16 tech and life sciences companies in Europe have disclosed about $190 million in exposure to SVB in the UK and the United States. Moonpig adds that SVB UK is one of ten lenders that provide senior debt facilities to the group as part of a strong banking syndicateASIA-PACIFICNITRO SOFTWARE (NTO.AX)Australia's productivity software maker Nitro Software Ltd (NTO.AX) said it had about $12.18 million of its global cash reserves held on deposit at SVB.
Factbox: Which companies are affected by SVB collapse?
  + stars: | 2023-03-13 | by ( ) www.reuters.com   time to read: +6 min
ROKU (ROKU.O)Streaming devices maker says it has about $487 million, or 26% of its cash and cash equivalents, held in deposits with SVB. CIRCLEUS cryptocurrency firm Circle says $3.3 billion of its $40 billion of USD Coin reserves are at SVB. BLOCKFIBankrupt crypto lender BlockFi Inc has roughly $227 million in unprotected funds at SVB, the Wall Street Journal reported on Friday. VIR BIOTECHNOLOGY (VIR.O)Biotech firm says it maintains operating accounts at SVB with about $220 million as of Friday. EUROPEAround 16 tech and life sciences companies in Europe have disclosed about $190 million in exposure to SVB in the UK and the United States.
Morgan Stanley's list of the biggest rising stars in the socially conscious investing space includes four U.S. stocks. But the stock hugely outperformed last year, rising 25% while the S & P 500 dropped 19.4%. DE 5Y mountain Deere & Co. Another name listed by Morgan Stanley is Eastman Chemical . Management estimates that the Kingsport plant will have a 15% rate of return for the company, while the other plants will likely be closer to 12%, Morgan Stanley said. EMN NFE 1Y mountain Eastman Chemical Nu Holdings , a Brazilian digital banking company that trades on the New York Stock Exchange, also made Morgan Stanley's list.
According to the Global Innovation Index 2022, global government R&D investment is growing and the UK is ranked fourth for global innovation (and third most innovative economy in Europe). "Space observation is vital for our planet — the UK invests in the European Space Agency and at the Space Cluster at Harwell, a significant science and innovation park." Jo Hawley, deputy director for aerospace, space and automotive at DBT, reported that the UK space sector spent £836 million on R&D in 2021. The company has reported strong growth of its life science research tools business, reflected in the international footprint of its commercial and distribution operations. The Department for Business and Trade can connect you with dedicated, professional assistance to locate R&D investment opportunities and support.
The dark comedy and shiny retrofuturism of “Hello Tomorrow!” may suggest a few alternative titles—“Mrs. Maisel in Space” or “The Jetsons Like Ike” or “Glengarry Glen Ross on Ketamine,” none of which would be wrong, exactly. Billy Crudup gives a genuinely remarkable performance as Jack Billings , a man who is mostly façade, which helps his mission—selling real estate on the moon. He’s a master at his craft and Mr. Crudup gives Jack sufficient self-awareness to make him charming, even when both he and a client know he’s playing a part and pushing a scheme. But even as the shilling for lunar time-shares plays out in a universe seemingly caught between eras, the production design is a constant wonder and curiosity, if not a positive distraction.
Scientists found no trace of disease in the preserved heart of a French woman who a pope beatified. Pauline Jaricot, whose health was poor, was supposedly "cured" after a visit with the Pope in 1837. Some members of the Catholic Church see the recent findings as a sign of a miracle. Despite living with poor heart health for most of her life, Catholics have said a visit to Pope Gregory XVI in 1837 miraculously "cured" her of heart disease. "No evidence that was inconsistent with natural and spontaneous conservation not mediated by the hand of man, which can be considered a miracle by the Roman Catholic Church, could be retrieved," the scientists said.
Ash from the eruption disrupted flights across Europe — including a time-sensitive shipment of experimental radioligand therapy that Sartor was expecting from Norway. Radioligand therapy, also called radionuclide or radiopharmaceutical therapy, is a targeted form of cancer treatment that delivers radiation directly to cancer cells. Once the radioactivity decays, it can no longer kill the cancer cells as effectively, which means radioligand therapy has a limited window of viability. Expensive to produce and ship fastNuclear medicine has been used to treat cancer for decades, and radioligand therapy itself is not new. In 2008, he traveled to a medical conference in Toronto where he heard about radioligand therapy for the first time.
The gene-editing startup Aera has hired biotech vets Akin Akinc as CEO and John Maraganore as chairman. CRISPR pioneer Feng Zhang's newest gene-editing venture has attracted two longtime leaders of the biotech giant Alnylam Pharmaceuticals, Insider has learned. Former Alnylam CEO John Maraganore is chairman of Aera. The SEND technology could allow gene-editing technology to treat more diseases. Based on Zhang's SEND research, Aera hopes to deliver gene-editing tools to more organs, ultimately expanding the number of diseases CRISPR can impact.
October 2022 Wang Linfang,92, molecular biologist Four members of China’s two most prestigious academic institutions died in October – in line with the average in recent years. October 2022 Wang Linfang,92, molecular biologist Four members of China’s two most prestigious academic institutions died in October – in line with the average in recent years. Zhang Guocheng, 91 Zhao Zisen, 90, developed China’s first practical optical fiber Tang Hongxiao, 91 The obituaries began accumulating. October 2022 Wang Linfang,92, molecular biologist Four members of China’s two most prestigious academic institutions died in October – in line with the average in recent years. October 2022 Wang Linfang,92, molecular biologist Four members of China’s two most prestigious academic institutions died in October – in line with the average in recent years.
Colossal Biosciences, a biotech company, says it will aim to revive the dodo using gene editing. This is the latest attempt to revive extinct animals in the face of the biodiversity crisis. The bird is the latest in the collection of long-gone animals scientists at the company want to revive. The startup has previously said it plan to recreate the Tasmanian wolf and the woolly mammoth. A stuffed dodo bird at the Natural History Museum on February 5, 2013, in London, England.
Ark Invest's Cathie Wood said Wednesday said artificial intelligence is the most important catalyst in every corner of her disruptive innovation strategy. "Many people say data is the new gold as they were talking about the cloud and other movements in technology, I think that's ever more true now with artificial intelligence," Wood said on CNBC's " Squawk Box ." "I think there's going to be a lot of commoditization in in this industry, in the whole artificial intelligence movement." In September, Ark Invest launched a new venture capital fund, targeting individual investors with a minimum investment of just $500. The actively managed Ark Venture Fund invests in 70% private firms and 30% public companies focused on technologically enabled innovation.
Shares of 4D Molecular Therapeutics could more than double as the biotechnology company revolutionizes gene therapy treatment, according to BMO Capital Markets. Analyst Kostas Biliouris initiated coverage of the stock with an outperform rating, saying in a Monday note to clients that 4DMT's utilization of a protein engineering method known as directed evolution can help take "gene therapy to the next level." "4DMT has built a powerful gene therapy platform that has been validated in clinic and is generating transformative therapies leading to potential multibillion dollar commercial opportunities," he said. "4DMT's gene therapy for wet AMD addresses the above key challenges, while its early clinical data point to a potential best-in-class profile that can drive > $5B in (risk-unadjusted) peak sales," Biliouris wrote. With a solid cash runway and just 140 employees working on five gene therapy programs, 4DMT's operating efficiencies differentiate it from competitors, he added.
In fact, the results reaffirm the reason why some dermatologists have changed the way they get their gel manicures or have stopped getting them altogether. “Tanning beds are listed as carcinogenic and UV nail lamps are mini tanning beds for your nails in order to cure the gel nail,” Curtis said. “I would recommend alternatives to gel nails, such as the new wraps that are available online.” (Gel nail wraps or strips are stick-on gel nail products that don’t always require being set by UV nail dryers.) Some salons use LED lights, which “are thought to emit either no UV light or much, much lower amounts,” Lipner said. Russak doesn’t get gel manicures very often but uses sunscreen and gloves when she does, she said.
Persons: , Julia Curtis, wasn’t, ” Curtis, Ludmil Alexandrov, ” Alexandrov, Julie Russak, Russak wasn’t, there’s, ” Russak, Shari Lipner, Lipner wasn’t, Curtis, , ” Lipner, Lipner, , Russak, Joshua Zeichner Organizations: CNN, Nature Communications, University of Utah, UCAR Center for Science Education, University of California, Dermatology, Presbyterian Hospital, Weill Cornell Medical Center, Mount Sinai Locations: San Diego, New York City, corneocytes, Mount
DHR 1Y mountain Danaher's 1 year stock performance Danaher is set to present at the JPMorgan Healthcare Conference on Tuesday afternoon. Now, management sees core sales growth up in the high single-digit range. In addition to the core revenue growth revision, management is now factoring in no growth coming from Covid-related testing. STZ 1Y mountain Constellation Brands 1-year stock performance;. As a subscriber to the CNBC Investing Club with Jim Cramer, you will receive a trade alert before Jim makes a trade.
Metric measurements — also known as the International System of Units, or SI — are managed by a formal international organization. The prefixes Brown came up with are ronna and ronto for 1027 and 10-27 and quetta and quecto for 1030 and 10-30. In fact, SI units used to be based on actual, real-life physical artifacts. "If everyone sticks to SI prefixes," Brown says, "you don't have to go on Wikipedia to find out how long a light-year is or the power in 1 jansky." Pražák proposed sticking to Greek words and letters.
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