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CNN —Ancient DNA recovered from the remains of a sixth century Chinese emperor who ruled during the country’s dark ages has shed some light on what the leader may have looked like. Emperor Wu ruled China as part of the Northern Zhou dynasty from 560 to 580 and is credited with unifying the northern part of ancient China during a particularly chaotic period. “Our analysis shows Emperor Wu had typical East or Northeast Asian facial characteristics.”The authors said they hoped ancient DNA might shed light on Wu’s cause of death. The genetic analysis showed that Emperor Wu intermarried with ethnically Han Chinese, China’s dominant ethnic group today. “It’s interesting to see the genetic study, but none of the findings of this genetic study are surprising at all,” Miller said.
Persons: Emperor Wu, Wu, , Shaoqing Wen, Tobias Houlton, University of Dundee , Houlton, Jeong Hoongwon, Jeong, ” Jeong, Franks, Bryan Miller, Miller, wasn’t, ” Miller, Organizations: CNN, Fudan University, University of Dundee, Seoul National University’s School of Biological Sciences, Han, Central, University of Michigan Locations: China, Mongolia, Shanghai, Seoul, North
Another key component was DNA from a living descendant of Samuel Washington. Samuel Washington, George Washington's younger brother, was buried in an unmarked grave at the cemetery at his Harewood estate (an interior view is pictured above) near Charles Town, West Virginia. Fortunately for the authors of the new study, “DNA analysis has come a long way since the early 2000s,” Cavagnino said. Further details came from 95,000 SNPs, an enormous volume of data targeting autosomal DNA (DNA that isn’t attached to sex chromosomes). “The search for Samuel Washington’s grave is no longer underway,” Marshall said.
Persons: George Washington’s, Samuel, Samuel Washington, , Charla Marshall, George, Courtney L, George Washington, Cavagnino, George Washington's, Harewood, Frances Benjamin Johnson, Samuel Washington’s, ” Cavagnino, Lucinda “ Lucy ” Payne, George Steptoe Washington Jr, Samuel Walter Washington, Dr, Lucy Payne, Connie J, Mulligan, , ” Mulligan, , that’s, — “, Augustine Washington, ” Marshall, Marshall, ” Mindy Weisberger Organizations: CNN, US Department of Defense DNA, West Virginia . Records, US Armed Forces DNA, Library, Zion Episcopal Church, Genomics, University of Florida, Scientific Locations: Washington, Harewood, Charles Town, West Virginia, Mount Vernon , Virginia, Zion
The rare find could help scientists further understand how changes in the human diet have led to the prevalence of cavities today. Uncovered during two excavations from 1993 and 1996, the teeth were among several human teeth and other remains found within a limestone cave in County Limerick in Ireland. One tooth had a surprising abundance of Streptococcus mutans (S. mutans), an oral bacteria that causes cavities. Researchers also believe the bacteria is not as commonly found within ancient teeth because the human diet included less refined sugar and fewer processed foods than are consumed today, Cassidy said. … ancient teeth can help us understand how the human oral microbiota (range of microorganisms) has evolved over time and the impact of these changes on human health in the past and today,” Humphrey said in an email.
Persons: Lara Cassidy, Cassidy, mutans, , , would’ve, Tannerella, mutans “, Louise Humphrey, ” Humphrey Organizations: CNN, Trinity College Dublin Locations: County Limerick, Ireland, France, London
Mario Tama | Getty ImagesAmgen is taking a new approach as it tries to stand out in a crowded field of drugmakers racing to develop the next blockbuster weight loss drug. It's too early to say how competitive Amgen will be in the budding weight loss drug space, which Novo Nordisk and Eli Lilly have so far dominated. Goldman Sachs also projects that between 10 million and 70 million Americans will be taking weight loss drugs by 2028. The sustained weight loss in Amgen's study appears to contrast with results seen in clinical trials on Zepbound and Wegovy. An injection pen of Zepbound, Eli Lilly’s weight loss drug, is displayed in New York City, U.S., December 11, 2023.
Persons: Mario Tama, Eli Lilly, Goldman Sachs, Zepbound, Eli Lilly's, Amgen's MartiTide, Caroline Apovian, Apovian, Joe Buglewicz, MariTide, Holly Lofton, Eli Lilly’s, Brendan McDermid, Reuters Amgen's, William Blair, Matt Phipps, Phipps Organizations: Getty, Novo Nordisk, Pfizer, Viking Therapeutics, Therapeutics, Zealand Pharma, Boehringer, Center, Weight Management, Wellness, Brigham, Women's, Washington Post, NYU Langone Health, Reuters, William Blair & Company, CNBC Locations: Thousand Oaks , California, Oaks , California, Novo, New York City, U.S
Why don’t humans have tails?
  + stars: | 2024-03-23 | by ( Mindy Weisberger | ) edition.cnn.com   time to read: +10 min
One of those led to shorter tails; the more of that protein the genes produced, the shorter the tails. A tail as old as timeFor modern humans, tails are a distant genetic memory. While Alu’s role “seems to be a very important one,” other genetic factors likely contributed to the permanent disappearance of our primate ancestors’ tails,” Xia said. In their experiments, the researchers found that when mice were genetically engineered for tail loss, some developed neural tube deformities that resembled spina bifida in humans. “Maybe the reason why we have this condition in humans is because of this trade-off that our ancestors made 25 million years ago to lose their tails,” Yanai said.
Persons: , Alu, AluY, Bo Xia, ” Xia, , Xia, Itai Yanai, ” Yanai, , Bo, Yanai, TBXT’s, Liza Shapiro, ” Shapiro, africanus, Shapiro, spina, Mindy Weisberger Organizations: CNN, Gene, Broad Institute of MIT, Harvard University, Institute for Systems Genetics, New York University Grossman School of Medicine, University of Texas, Scientific Locations: Austin, Kenya
CNN —Bruce Willis’s youngest daughter Tallulah Willis is sharing for the first time that she was diagnosed with autism. Tallulah Willis, 30, shared her health update over the weekend when she posted a throwback video on her Instagram page of herself with her father. In the video, Bruce Willis is holding a young Tallulah in his arms while appearing at a red carpet event. (From left) Bruce Willis with daughter Tallulah Willis in New York City in 2015. Tallulah Willis is the youngest daughter of Bruce Willis and ex-wife Demi Moore.
Persons: CNN — Bruce Willis’s, Tallulah Willis, Bruce Willis, Tallulah, , I’ve, Kevin Mazur, it’s, Daniel Geschwind, Gordon, Virginia Macdonald, , ” Geschwind, Demi Moore, Rumer, Scout Willis, Moore – Organizations: CNN, UCLA, FOX, Vogue Locations: New York City
For those assigned female at birth, puberty blockers pause the development of breasts, wider hips or a menstrual period. Here’s what else you should know about puberty blockers and, if you’re a parent, whether they’re something your child needs. “Many kids have already completed puberty by the age of 13 or 14 … so we start blockers when puberty starts,” Forcier said. The one right way to do things is to listen to the patient.”How safe are puberty blockers? Some people worry that children who take puberty blockers may change their minds about their gender identity later in life.
Persons: , Michelle Forcier, it’s, Forcier, ” Forcier, , Melina Wald, Wald, Lauren Wilson, who’s, shouldn’t, Wilson, , ” Wilson, There’s, ” CNN’s Tara John Organizations: CNN, Health Service, Warren Alpert Medical, Brown University, Folx Health, Reuters, Health, Columbia University Medical, American Academy of Pediatrics, Columbia University Locations: Rhode Island, United States, Connecticut, New York, Montana, Amsterdam, Netherlands
We delve into a wide range of topics, including the science behind new weight loss drugs, weight gain around menopause, and the evolutionary reasons behind why losing weight is so hard. Yeo truth No. 1: Losing weight ‘ain’t supposed to be easy’Losing weight goes against our self-preservation mechanisms. “I think we do have to fix our food environment; I think some people need to eat less food. But I think we need to love our food.”We hope these five tips help you think about food (and eating) in a more productive and less toxic way.
Persons: Sanjay Gupta, ” Giles Yeo, ” Yeo, Yeo, — Yeo, , , , Gene, it’s, “ Don’t, , Sanjay Gupta’s, Lindy West Organizations: CNN, American Medical Association, US Centers for Disease Control, University of Cambridge, Genetics, Obesity
We asked dermatologists whether Eto's skincare routine or just luck and genetics have helped her achieve flawless skin. AdvertisementEto has had a skincare routine for 60 yearsEto has followed a daily skincare routine for the last 60 years, using specific products from a Japanese brand, Manavis, for the past 15 years. Alster said that Eto's skincare routine has likely "minimally" contributed to her wrinkle-free skin, and having so many steps is unnecessary. Plus, Vitamin C helps protect the skin against the sun and has been linked to decreases in wrinkles, according to Oregon State University. Plus, research suggests that gut health and skin health are interconnected.
Persons: , Yuri Lee, Toshiko, Lee, Derek V, Chan, doesn't, Tina Alster, Alster, Miki, Dr, Will Bulsiewicz Organizations: Service, Business, Eto, pats, American Academy of Dermatology, BI, Skin Cancer Foundation, Washington Institute of, Oregon State University Locations: LA, Manhattan
The stem cells will also make it easier for conservation scientists to study the Asian elephant’s unique biology. An Asian elephant stem cell line stained in different colors to highlight different elements. Courtesy ColossalEngineering a woolly mammoth hybridThe elephant stem cells also hold the key to the mammoth’s rebirth. The research team at Colossal has already analyzed the genomes of 53 woolly mammoths from ancient DNA recovered from fossils. The number of modifications needed to make an Asian elephant resistant to the cold would be broadly similar, he said.
Persons: George Church, Ben Lamm, Eriona, Eriona Hysolli, John Davidson “, , Hysolli, Oliver Ryder, Ryder, ” Ryder, Christopher P, Michel “, Ben’s, Lamm, , That’s, We’ve, tramping, Colossal Organizations: CNN, Harvard University, Church, Dallas, Biosciences, Colossal, San Diego Zoo Wildlife Alliance, Colossal Biosciences, Christopher Locations: Dallas, , Siberia
Take Dennis and Douglas. In high school, they were so alike that friends told them apart by the cars they drove, they told researchers in a study of twins in Virginia. Most of their childhood experiences were shared — except that Dennis endured an attempted molestation when he was 13. At 18, Douglas married his high school girlfriend. Why do twins, who share so many genetic and environmental inputs, diverge as adults in their experience of mental illness?
Persons: Dennis, Douglas Organizations: University of Iceland, Karolinska Institutet Locations: Virginia, Sweden
Sleep is an important lifestyle factor in reducing risk for type 2 diabetes, a new study has found. In terms of risk for type 2 diabetes, there wasn’t a significant difference between those with normal sleep and those who slept six hours. And even for those who ate the healthiest, their diet didn’t offset the effects of insufficient sleep on diabetes risk. The findings are also based on participants’ recollections of their food and sleep habits, according to the study. Confirming a causal relationship “would require randomized trials intervening on sleeping habits to increase sleep time and see if this reduces risk of diabetes in those at risk, e.g.
Persons: CNN —, Dr, Diana Nôga, ” Nôga, , Leana Wen, Wen wasn’t, ” Wen, Naveed Sattar, ” Sattar, Wen Organizations: CNN, JAMA, biosciences, Uppsala University, Lighthouse Films, George Washington University Milken Institute School of Public Health, University of Glasgow Locations: Sweden, United Kingdom, Scotland,
Here's what's in store for Timothée Chalamet if Villeneuve gets the green light. "'Dune Messiah' was written in reaction to the fact that people perceived Paul Atreides as a hero. Paul Atreides will be the Emperor of the universe in "Dune 3"Timothée Chalamet as Paul Atreides on Calodan in "Dune." "Dune 3" would also introduce Paul and Chani's childrenZendaya as Chani and Timothée Chalamet as Paul Atreides in "Dune." AdvertisementPaul may exile himself to the desert at the end of "Dune 3"Timothée Chalamet as Paul Atreides in "Dune."
Persons: Denis Villeneuve, Frank Herbert's, Chalamet, Villeneuve, , Timothée Chalamet, Paul Atreides, Paul, Jessica, Rebecca Ferguson, Baron Harkonnen, Stellan, Emperor Shaddam, Christopher Walken, That's, Alia —, Anya Taylor, Joy, Paul's, Zendaya, Princess Irulan, Florence Pugh, He's, Chani, Frank Herbert didn't, , Alia Organizations: Service, Rotten, Empire, Times, Warner Bros, Guild, Warner Bros ., Villeneuve Locations: South Korea, Hollywood, Arrakis, Chalamet
As a single mother and professor, I struggled financially, so we moved into a rental on campus. My two daughters grew up on the college campus where I worked, and the students became mentors. As a single parent, I raised two daughters — now 24 and 18 — in a tiny campus rental with a view of a white barn and sloping mountains. A pragmatic horticulturist, he'd watched my children walk through his yard to the bus stop each morning. AdvertisementBut what I couldn't explain was my attachment to this college, its students, and its support system.
Persons: , Tom, he'd, Rodney Lytle, Alma Shippy, Painter Dave, Warren, Annie, Sierra, I'd, I've Organizations: Service, Warren Wilson College, Sierra Locations: North Carolina, Tallulah
The 65-year-old billionaire says he now regrets stressing about his age every time he hit a big numerical milestone. Just one thing: I wish I hadn't thought I was getting old at every milestone [birthday]… 30,40,50," Cuban wrote in a recent post on Threads. You may need to change your habits as you age to stay healthy, Cuban noted. Rather than getting frustrated about those changes, embrace them, Cuban wrote on Threads. Disclosure: CNBC owns the exclusive off-network cable rights to "Shark Tank," which features Mark Cuban as a panelist.
Persons: Mark Cuban, , Cuban, Becca Levy, Cuban's, Steve Kamb, Yoav Bergman, Bergman, he's, Recode, That's Organizations: Dallas Mavericks, Yale University, Foundation University Islamabad, CNBC Locations: Pakistan, Cuban
Frank Noble is 85 years old and his routine that includes regular exercise, gardening, and golfing. download the app Email address Sign up By clicking “Sign Up”, you accept our Terms of Service and Privacy Policy . AdvertisementThis as-told-to essay is based on a conversation with Frank Noble, an 85-year-old from Porepunkah in Victoria, Australia. I'd probably spend six hours a day on average in the garden three or four days a week. Frank Noble grows his own vegetables.
Persons: Frank Noble, Noble, , I've, I'm, I'd, It's, Betty, she's, There's Organizations: Service, Victorian School of Forestry, Forests Commission, National Parks, Central Locations: Porepunkah, Victoria, Australia, Creswick, Forests, Forests Commission Victoria, Central Gippsland
President Biden will issue an executive order Wednesday seeking to restrict the sale of sensitive American data to China, Russia and four more countries, a first-of-its-kind attempt to keep personally identifying information from being obtained for blackmail, scams or other harm. The president will ask the Justice Department to write rules restricting the sale of information about Americans’ locations, health and genetics to China, Russia, Iran, North Korea, Cuba and Venezuela, as well as any entities linked to those countries. The restrictions would also cover financial information, biometric data and other types of information that could identify individuals and sensitive information related to the government. The White House said this kind of sensitive data could be used for blackmail, “especially for those in the military or national security community,” and against dissidents, journalists and academics. The new restrictions would be the United States’ first-ever broad prohibition on the sale of digital data to individual countries in an era when companies known as data brokers assemble huge amounts of information on people, from favorite hobbies to household income and health conditions, and then typically sell it to marketers that target them with ads.
Persons: Biden, United States ’ Organizations: Department Locations: China, Russia, Iran, North Korea, Cuba, Venezuela, United States
If you want to understand how different the human and animal medicine and vaccine industries have historically been, you don't need to look much further than weight loss drugs. When Pfizer spun off its animal health business in 2013 creating Zoetis, about 65% of the company's business was livestock-related. That has flipped now, with 64% of the company's revenue coming from products for companion animals like cats and dogs. Peck credits the Pfizer spinoff for allowing Zoetis to better balance what the company wanted to do in animal health versus the human health side. A similar product was approved for cats, marking the first time that monoclonal antibody treatments, which have become increasingly popular for treating human illnesses, have been used to treat pet osteoarthritis pain.
Persons: Kristin Peck, Eli Lilly, Peck, Zoetis, We've, it's, We'll Organizations: CNBC, Novo Nordisk, Pfizer, AstraZeneca, FDA
Wall Street returned to its winning ways this week — and Nvidia 's blowout earnings report Wednesday night was a big reason why. Twenty-six of our 32 portfolio stocks have delivered their results this earnings season (we didn't own Abbott Labs at the time of its report). It was a muted week for macroeconomic data, but we did get a slightly better-than-expected January existing home sales report on Thursday. In the week ahead, two more Club names are set to report earnings before a market-moving economic update arrives Thursday morning. The two other reports of note are the January new home sales report on Monday and ISM Manufacturing report on Friday.
Persons: Dow, we'll, bode, We're, Li Auto, Krystal, Arcutis, MARA, Iovance, Goldman Sachs BDC, CRON, BUD, Papa, LEV, Ginkgo, Jim Cramer's, Jim Cramer, Jim, Spencer Platt Organizations: Nvidia, Nasdaq, Dow Jones, Dow, Palo Alto Networks, Bausch Health, Coterra Energy, Abbott, Companies, TJX, Marshalls, TJX Companies, Berkshire Hathaway, Krystal Biotech, Alpha Metallurgical Resources , Inc, Fidelity National Information Services Inc, Animal Health, ELAN, Public Service Enterprise Group, Surgery Partners, BioCryst Pharmaceuticals Inc, Outdoor Holdings, Enlight Renewable Energy Ltd, Kosmos Energy, Playtika, Video Communications, TiRobot Corp, IRB, SBAC Communications Corporation, HEICO Corporation, FS KKR, Archer Aviation Inc, TransMedics, Sterling Construction Company, AES, Cruise Line Holdings, Lowe's Companies, American Electric Power Company, Bank of Nova, APLS Pharmaceuticals, Bank of Montreal, BMO, Devon Energy, Solar Inc, Technologies, Lab, Virgin Galactic Holdings, Splunk Inc, eBay, EBAY, Luminar Technologies, Agilent Technologies, G Foods, Masimo Corp, Baidu, Parts Inc, Icahn Enterprises, Viatris Inc, ACM Research, Golden Ocean Group, EMCOR, Industries, NRG Energy, Dycom, Editas, UWM Holdings Corporation, Vistra Energy, Marathon Digital Holdings, AMC Entertainment Holdings, Paramount Global, IonQ Inc, International, HP, Monster Beverage Corporation, Cronos, Birkenstock Holding, Anheuser, Busch InBev, Body, Brink's Company, Flags Inc, Papa John's, ACI, Hormel, Lion Electric Company, BlackRock TCP, Dole plc, DOLE, Fisker Inc, Dell Technologies, Ginkgo Bioworks Holdings, Autodesk, Green Brick Partners, Hewlett Packard Enterprise, Veeva Systems, INTTEST Corporation, Jim Cramer's Charitable, CNBC, New York Stock Exchange, Getty Locations: New York City, U.S, Salesforce, Maxx, Bank of Nova Scotia, BlackRock, Cayman
CNN —Scientists working in the Amazon rainforest have discovered a new species of snake, rumored to be the biggest in the world. Green anacondas are the world’s heaviest snakes, according to the UK’s Natural History Museum, which noted that the heaviest individual ever recorded weighed 227 kilograms (500 pounds). It measured 8.43 meters long (27.7 feet) and 1.11 meters (3.6 feet) wide. Professor Bryan Fry/The University of QueenslandBut experts studying the creatures discovered that the newly identified northern green anaconda species diverged from the southern green anaconda almost 10 million years ago, and they differ genetically by 5.5%. Habitat degradation, forest fires, drought and climate change threaten rare species like the anacondas, which exist in such rare ecosystems, he added.
Persons: anacondas, , Bryan Fry, anaconda, ” Fry, Will Smith Organizations: CNN —, University of Queensland, Geographic, anaconda Locations: Ecuadorian, Baihuaeri Waorani Territory, South America
A leading food and drug chemist says most memory supplements are likely bogus. But getting enough protein, from plant sources like nuts, beans, and whole grains can help. There are hundreds of supplements out there promising to "boost" your brain health or perform a "miracle" for your mind. Science shows plant proteins and mixed berries are great for aging brainsSandy Schulze/APSchwartz looks to the long-term Nurses Health Study for better evidence. It's a landmark public health study that has been running in the US since 1976.
Persons: Joseph Schwartz, It's, Sandy Schulze, Schwartz, munch Organizations: Science, Society, McGill University, Health, Nurses Health
The woman behind the next big thing in cancer treatment
  + stars: | 2024-02-20 | by ( Katie Hunt | ) edition.cnn.com   time to read: +12 min
Christine Olsson/AFP/Getty ImagesWu’s research focused on small mutations in cancer tumor cells. However, in many cases, cancer vaccines have failed to live up to their promise — largely because the right target hasn’t been found. “This is a fantastic discovery.”By sequencing DNA from healthy and cancer cells, Wu and her team identified a cancer patient’s unique tumor neoantigens. More work is needed before they are a viable treatment options for many cancer patients. To show that these type of cancer vaccines work, much larger randomized control trials are needed.
Persons: Catherine Wu, Boston’s Dana, , , Wu, Lendahl, Dr Patrick Ott, Sam Ogden, Honjo, James Allison, Tasuku Honjo, James P Allison, Christine Olsson, ” Hans, Gustaf Ljunggren, Matt Stone, “ I’m, ” Wu, ” Lendahl, you’ve, It’s, ” Barbara Brigham, BioNTech, ” CNN’s Brenda Goodman Organizations: CNN, Farber Cancer Institute, Royal Swedish Academy of Sciences, Karolinska, Getty, US Food and Drug Administration, FDA, MediaNews, Boston Herald, Merck, Moderna, , Covid Locations: Sweden, BioNTech, Rome
Read previewA personal trainer and college student lost over 13 pounds in a month while eating a Domino’s pizza every day, to prove that it’s possible to enjoy treats and lose fat as long as you’re in a calorie deficit . “Foods shouldn't be feared just because they've undergone some sort of processing,” Jayden Lee, 18, Lee told Business Insider. Typically, weight loss of one to two pounds a month on average is deemed safe. AdvertisementHowever, Lee doesn't recommend people try to follow his daily pizza diet to lose weight, and neither does Ludlam-Raine. “Occasional indulgence in foods like pizza is part of a balanced diet and can help prevent feelings of deprivation,” Ludlam-Raine said.
Persons: , they've, Jayden Lee, Lee, dietitian Nichola Ludlam, Raine, Jayden Lee Lee, , , ” Lee, Jordan, Lee isn’t, won’t, Lee doesn't, ” Ludlam, Domino's Organizations: Service, Business, USDA Locations: Portsmouth, UK
While everyone’s gait differs, you may develop an abnormal gait due to illness, injury, genetics, or issues with your legs or feet. What a gait analysis can uncover about your healthAssessing gait can predict gross motor delays in kids, fall risks in older adults and, when coupled with a cognition decline, the risk of dementia. “We’re looking at gait speed, cadence — the number of steps per minute — variability in gait speed and cadence, step length, the time both feet are spent on the ground, stance and more,” said Stephanie Wakeman, a physical therapist and OneStep’s director of clinical operations. But if you’re interested in a gait analysis to boost your athletic performance or prevent injury, you may have to pay out of pocket. “I would also love it if gait analysis was part of the recovery program for anybody who has knee, ankle or hip surgery,” Heiderscheit said.
Persons: Gait, , Bryan Heiderscheit, Achilles tendinopathy, ” Heiderscheit, “ It’s, Heiderscheit, , Stephanie Wakeman, Wakeman, ” Wakeman, you’re, Melanie Radzicki McManus Organizations: CNN’s, CNN, American Medical, Association, University of Wisconsin, Badger, US Food and Drug Administration Locations: orthopedics, Madison
Three of my grandparents lived past the age of 90. My paternal grandmother, Mimi, lived the longest, to the age of 95. Sophie Katzman's paternal grandmother, Grandma, in her 80s. This is her grandfather, Papa, and her grandmother, Mimi, when they were younger. Sophie Katzman's paternal grandparents, Mimi and Papa, both took daily walks.
Persons: Mimi, , Mimi —, Grandma, Snacking, Sophie Katzman's, Sophie Katzman, Papa, Jack LaLanne's, Shakespeare Organizations: Service, Oil Locations: Florida, Japan, Israel
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