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☆ Doctors say RFK Jr.’s anti-Ozempic stance perpetuates stigma and misrepresents evidence
▼ + stars: | 2024-11-17 | by ( Meg Tirrell | ) edition.cnn.com time to read: +9 min

Sanjay Gupta Reports: Is Ozempic Right For You?” at 8 p.m. Sunday, November 17, on CNN. Even as they agree that it’s important to address growing rates of diabetes and obesity, doctors in that field say Kennedy’s plans miss the mark. Not everyone with obesity will want the drugs, and for some, they may have strong side effects such as nausea. Doctors who treat people with obesity suggest that fixing the food system shouldn’t be mutually exclusive with using weight-loss medications, when appropriate. “But a lot of his thinking is like ‘A plus B plus C plus miracle, and you’ve got an answer.’”

Persons: Sanjay Gupta, Robert F, Kennedy Jr, Donald Trump’s, —, ” Kennedy, Greg Gutfeld, Kennedy, European Union “, Ozempic, ideation, Michael Osterholm, ” Osterholm, “, Trump, he’s, Kennedy’s, Josh Green, that’s, Kennedy —, ”, Jody Dushay, Dr, Angela Fitch, “ We’ve, ” Fitch, we’ve, ‘, ” Dr, Daniel Drucker, ” Drucker, don’t, they’re, Fitch, Doctors, Elon Musk, who’s, ” Musk, It’s, he’d, you’ve, ’ Organizations: CNN, US Department of Health, Human Services, Fox News, Novo Nordisk, Danish Medicines Agency, European Union, US Food and Drug Administration, Infectious Disease, University of Minnesota, FDA, US Centers for Disease Control, National Institutes of Health, Centers, Medicare, Services, HHS, Hawaii Gov, Environmental Protection Agency, BMI, Harvard Medical School, Beth Israel Deaconess Medical, Fox, CNN Health, NPR, Trump Locations: Denmark, America, Hawaii, Samoa

☆ Lost and found: Life after Ozempic and other weight-loss drugs was just the start for these four people
▼ + stars: | 2024-11-16 | by ( Carma Hassan | Zoe Todd | ) edition.cnn.com time to read: +19 min

The 22-year-old content creator approached her doctor about weight loss medication in March, before she had breast reduction surgery. Method: Zepbound, diet changes, exerciseZepbound, diet changes, exercise Duration: Took Zepbound from May to October. “The breast reduction was a big step, but the weight loss put a little cherry on top,” she said. Method: Compounded semaglutide, diet changes, exerciseCompounded semaglutide, diet changes, exercise Duration: Took compounded semaglutide from February to May. Method: Ozempic, diet changes, exerciseOzempic, diet changes, exercise Duration: Took Ozempic from May 2020 to October 2023“I was very close to being 300 pounds.

Persons: Sanjay Gupta, ”, Eduardo Grunvald, Alexus Murphy, CNN Alexus Murphy, Alexus, Murphy, It’s, it’s, “, ” Murphy, Alexus Murphy She’s, “ It’s, “ I’m, you’re, Steven Ray, Ray, he’s, ” Ray, Becky Bell, CNN Becky Bell, she’s, Bell, ” “, ” Ozempic, Max Nazaire, ” Bell, Nazaire, She’s, Ozempic, Dustin Gee, CNN Dustin Gee, didn’t, I’ve, –, ” Gee, Gee, ‘, Cristian, Emanuel, Jackson, Alex, Gee's, Dr, CNN’s Tal Yellin Organizations: CNN, CNN — Research, University of California, BMI, Houston, Inland, Health, Medi, Cal, US Food and Drug Administration, FDA, “, Bell, Ozempic, Mayo Clinic Diet, Get CNN, CNN Health Locations: San Diego, California, Houston, Woodstock , Georgia, Safe Haven, Peru, Bellingham , Massachusetts, Lima

☆ Trump’s latest controversial Cabinet pick could have a huge impact on Americans’ health and lives
▼ + stars: | 2024-11-15 | by ( Stephen Collinson | ) edition.cnn.com time to read: +11 min

The president-elect’s previous selections for director of national intelligence, attorney general and defense secretary could change the country and the world in the long term. The US Department of Health and Human Services secretary has a massive platform and huge power to influence the information that Americans have and the choices they make. “I guess if you like health and you like people who live a long time, it is the most important position,” Trump said. Christina House/Los Angeles Times/Getty ImagesAnother health expert and former US Centers for Disease Control and Prevention acting director condemned the pick. The highly contagious disease is preventable with two doses of the measles vaccine that most Americans get as kids.

Persons: Donald Trump’s, Robert F, Kennedy Jr, “, Kennedy, Trump’s MAGA, Kennedy’s ascendency, Bobby ’ Kennedy, ” Trump, Bobby, ”, Matt Gaetz, Trump, Pete Hegseth, Tulsi Gabbard, Bashar al, Assad, Carlos Barria, Jake Tapper, Indiana Sen, Jim Banks, Jake, Donald Trump, ” Banks, —, ’ Kennedy, he’d “, Dr, Ashish Jha, Covid, CNN’s Wolf Blitzer, Jha, Christina House, Richard Besser . Besser, CNN’s Kaitlan Collins, kindergartners, Mandy Cohen, CNN’s Meg Tirrell, who’s, ” Cohen, Lex Fridman’s, CNN’s Kasie Hunt, don’t, –, ’, won’t, Mitch McConnell — Organizations: CNN, National Institutes of Health, RFK Jr, Trump, US Department of Health, Human Services, Trump’s, Fox News, America, Reuters, Biden, Brown University’s School of Public Health, Republican, Democratic, “ RFK, Los Angeles Times, US Centers for Disease Control, World Health Organization, CDC, Milken, Health Summit, Trump Cabinet, Senate, FBI, GOP Locations: Lago, Florida, Palm Beach , Florida, Washington, Huntington Park , California

☆ Eli Lilly's Zepbound and Mounjaro are no longer in shortage. Here's where their sales still disappointed
▼ + stars: | 2024-10-30 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +4 min

An Eli Lilly & Co. Zepbound injection pen arranged in the Brooklyn borough of New York, US, on Thursday, March 28, 2024. During an earnings call Wednesday, Eli Lilly instead blamed it on drug wholesalers cutting inventory of Zepbound and Mounjaro. On the earnings call, Eli Lilly executives insisted that underlying demand for the medicines remained strong. No," Eli Lilly CEO Dave Ricks said, pointing instead to "a lot of lumpiness in channel stocking." Ricks said Eli Lilly had yet to begin what the company calls "demand-stimulating activities," or advertising and promoting, for Zepbound.

Persons: Eli Lilly, Mounjaro, StreetAccount ., Geoff Meacham, Jared Holz, Mizuho, Carter Gould, Eli Lilly's, tirzepatide, Dave Ricks, Ricks, Lilly Organizations: U.S, StreetAccount, Citi, Barclays, Food and Drug, FDA Locations: Brooklyn, New York, Lilly

☆ Trump’s plan to radically remake government with RFK Jr. and Elon Musk
▼ + stars: | 2024-10-30 | by ( Zachary B. Wolf | ) edition.cnn.com time to read: +9 min

‘Go wild’ with RFK Jr.Trump has promised to give Kennedy leeway to remake the way the government health apparatus protects Americans. Robert F. Kennedy Jr. and former President Donald Trump shake hands during a campaign rally at Desert Diamond Arena on August 23, 2024, in Glendale, Arizona. Both Trump and Kennedy have expressed vaccine skepticism, and Kennedy has been a longtime activist pushing debunked theories about vaccines. In a potential new Trump administration, Musk promises a reinvention of the federal bureaucracy. “Let’s start from scratch,” Musk said at an event in October in Pittsburgh, suggesting a drastic remaking of the federal bureacracy.

Persons: Donald Trump, Robert F, Kennedy Jr, “, Trump, Kennedy, “ I’m, ” Trump, Anne Frank, Rebecca Noble, we’ve, ” Kennedy, Aaron Pellish, Trump’s, “ Trump’s, CNN’s Meg Tirell, Musk, It’s, Musk’s, ” Musk, Elon Musk, Dave McCormick, Michael Swensen, CNN’s David Goldman, “ Musk, ” Goldman, Larry Summer, ” Summers, Summers, Mike Johnson, ”, ” Johnson, Kamala Harris, Johnson Organizations: CNN, Trump, Elon, RFK Jr, Madison, PAC, New York Times, Desert Diamond Arena, HHS, Department of Health, Human Services, CDC, Centers, Disease Control, FDA, Food, Drug Administration, National Institutes of Health, USDA, Department of Agriculture, SpaceX, Tesla, “ Department, Government, Fox News, Congressional, Social Security, Republicans, Health Locations: Nazi Germany, Glendale , Arizona, Pittsburgh, Pennsylvania, White

The FDA’s announcement on Oct. 2 declaring the shortage over meant that compounding pharmacists had to stop filling tirzepatide prescriptions. Simone Williams, 50, of Spartanburg, S.C was prescribed compounded tirzepatide in June 2023 after her Mounjaro savings card expired. Williams began taking compounded tirzepatide for weight loss last year after her Mounjaro savings card expired. Tirzepatide was on the FDA’s drug shortage list for nearly two years. ‘Peace of mind’Meanwhile, patients and compounding pharmacists are celebrating the FDA decision to allow tirzepatide compounding to continue.

Persons: Lilly’s, Mounjaro, Zepbound, semaglutide, Wegovy, drugmakers, tirzepatide, “, Simone Williams, S.C, Simone Williams Simone Williams, Williams, ” Williams, she’s, I’m, ”, Lilly, Michael Ganio, Ganio, Dr, Christopher McGowan, ” McGowan, ” Lilly, Jared Shapiro, ’ ” Shapiro, Elizabeth Kenly, ” Kenly, Kenly Organizations: Drug Administration, FDA, Association, American Society of Health, System, Outsourcing, Alliance, Pharmacy, APC Locations: Spartanburg, Spartanburg , South Carolina, U.S, Cary , North Carolina, Graham , North Carolina

☆ ‘Greed, greed, greed’: Sanders demands Ozempic maker lower prices
▼ + stars: | 2024-09-24 | by ( Meg Tirrell | Tami Luhby | ) edition.cnn.com time to read: +7 min

“We are very committed to making sure that Americans have access at an affordable price point for our medicines,” Jorgensen replied. Similarly, Wegovy’s list price is $1,349 in the US, but it costs $186 in Denmark, $140 in Germany and $92 in the United Kingdom, he said. Tuesday’s hearing boiled down to a familiar argument over who is responsible for the US’s higher prices: drug companies that set starting – or “list” – prices or pharmacy benefit managers, the middlemen that negotiate discounts on those list prices in exchange for favorable insurance coverage and access. Jorgensen said Novo Nordisk pays back about 75% of its medicine sales in rebates, discounts and fees, so the net price it receives is far lower than the list price. “The broad totality is that less patients have access to our medicines when we lowered the price,” Jorgensen told Sen. Maggie Hassan, D-New Hampshire, after she pressed him to reduce list prices.

Persons: Sen, Bernie Sanders, ” Sanders, Lars Fruergaard Jorgensen, ” Jorgensen, “, Sanders, Jorgensen, it’s, Maggie Hassan, drugmakers, ”, PBMs, scot, ” Sen, Tim Kaine, Roger Marshall, Eli Lilly, Dr, Sanjay Gupta, Tammy Baldwin Organizations: CNN, Nordisk’s, US, Health, Education, Labor, Pensions, Yale, Novo Nordisk’s Ozempic, Novo Nordisk, Pharmaceutical Care Management Association, Nordisk, Novo Nordisk’s, Federal Trade Commission, CVS, Cigna’s, Republican, Wegovy’s, CNN Health, Medicare, Services Locations: United States, Danish, America, Canada, Denmark, Germany, United Kingdom, New Hampshire, Big, Virginia, Kansas, Novo, Wisconsin

☆ GLP-1 pills are coming, and they could revolutionize weight-loss treatment
▼ + stars: | 2024-09-17 | by ( Meg Tirrell | ) edition.cnn.com time to read: +7 min

CNN —Jared Holz thought about taking one of the new GLP-1 drugs for weight loss for months before he actually filled the prescription. At least a dozen similar experimental weight-loss drugs designed to be taken as pills are working their way through clinical trials, with the most advanced now in the third and final stage of testing. Dushay cited hopes that pill versions of GLP-1 drugs could ease shortages, come at lower cost and enhance convenience. The oral GLP-1 raceRight on the heels of oral semaglutide is a group of drugs led by Eli Lilly’s orforglipron, an oral medication that also targets GLP-1, which is a hormone implicated in insulin regulation, appetite and digestion. Drugmakers including Pfizer and Roche, as well as smaller companies like Structure Therapeutics, Terns Pharmaceuticals and Viking Therapeutics, also have oral weight-loss drugs in earlier stages of development, BMO research shows.

Persons: Jared Holz, ” Holz, ”, Jody Dushay, Dushay, ” Dushay, it’s, Rybelsus, Jorge Moreno, “, ” Moreno, Eli Lilly’s orforglipron, Lilly, Evan Seigerman, amycretin, who’ve, Dr, Sanjay Gupta, Holz, he’s, he’d Organizations: CNN, Harvard Medical School, Beth Israel Deaconess Medical, Novo Nordisk, US Food and Drug Administration, Yale School of Medicine, BMO Capital Markets, Pfizer, Roche, Therapeutics, Terns Pharmaceuticals, Viking Therapeutics, BMO, Nordisk, European Association for, Diabetes, Inversago Pharma, CNN Health Locations: Danish, Novo

☆ Ozempic predecessor suggests potential for GLP-1 drugs in Alzheimer’s in early trial
▼ + stars: | 2024-07-30 | by ( Meg Tirrell | ) edition.cnn.com time to read: +7 min

“This is the first study that actually looked at a relatively large number of patients for whether there is any neuroprotective effect in Alzheimer’s disease,” Edison said. The trial enrolled predominantly people with mild Alzheimer’s disease, measured by a test known as the Mini-Mental State Examination, a scale that goes up to 30. The GLP-1 drug class also includes Eli Lilly’s Mounjaro and Zepbound, which use the active ingredient tirzepatide, which mimics not just the hormone GLP-1 but another called GIP. But it hasn’t announced any trials of its GLP-1 drugs in Alzheimer’s. GLP-1 drugs can have side effects, though, primarily gastrointestinal problems like nausea and vomiting.

Persons: liraglutide, “, ”, Maria Carrillo, Carrillo, Paul Edison, ” Edison, Edison, Eli Lilly’s Mounjaro, Alzheimer’s Lilly, hasn’t, Lilly, Lars Fruergaard Jorgensen, there’s, Dr, Sanjay Gupta, semaglutide Organizations: CNN, Alzheimer’s Association International Conference, Alzheimer’s Association, Novo Nordisk, Imperial College London, ”, Nordisk, ” Novo Nordisk, CNN Health, University of Oxford, Alzheimer’s Society, Alzheimer’s Locations: United Kingdom, Philadelphia, Alzheimer’s, ” Novo, Danish

☆ Twice-yearly shot proves successful at preventing HIV infection among women, trial data shows
▼ + stars: | 2024-07-24 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +9 min

CNN —Two shots a year of a drug currently used to treat HIV infections were dramatically effective at preventing infections in a study among young women and adolescent girls in Africa. The twice-yearly injection of the drug lenacapavir can provide total protection against HIV infections, demonstrating 100% efficacy in Phase 3 trial data released by drugmaker Gilead and published Wednesday in the New England Journal of Medicine. The twice-a-year injections of lenacapavir could add another option at preventing HIV infections to the toolbox. The latest Phase 3 findings are part of Gilead’s PURPOSE program, which comprises five HIV prevention trials around the world. “While Gilead awaits additional phase 3 clinical trial data and the potential regulatory filings for HIV prevention administered twice-yearly, it is too early to state the price of lenacapavir for PrEP (prevention).

Persons: drugmaker Gilead, ” Linda, Gail Bekker, Desmond Tutu, “, ”, Dan Barouch, hasn’t, Gilead, Dr, Jason Zucker, Barouch, ” Zucker, Lenacapavir, Gilead spokeperson, lenacapavir, Sanjay Gupta, Daniel O’Day Organizations: CNN, New England, of Medicine, International AIDS, PrEP, University of Cape, International AIDS Society, Center, Virology, Vaccine, Beth Israel Deaconess Medical, United, lenacapavir, Columbia University Irving Medical Center, ”, US Food and Drug Administration, AIDS, CNN Health, People’s Medicines Alliance, Medicines Locations: Africa, Munich, University of Cape Town, South Africa, Uganda, Argentina, Brazil, Mexico, Peru, Thailand, United States, United Kingdom, Germany, Gilead, Europe

☆ Popular weight loss and diabetes drugs linked to increased risk of rare form of blindness
▼ + stars: | 2024-07-03 | by ( Deidre Mcphillips | ) edition.cnn.com time to read: +6 min

CNN —People who take Ozempic or Wegovy may have a higher risk of developing a rare form of blindness, a new study suggests. The condition is relatively rare — up to 10 out of 100,000 people in the general population may experience it — but the doctors noted three cases in one week, and each of those patients was taking semaglutide medications. The risk was found to be greatest within the first year of receiving a prescription for semaglutide. Semaglutide prescriptions have soared in the US, which could raise the number of people at risk for a potential side effect. But the large number of people who are taking semaglutide should raise confidence that the absolute risk of developing NAION as a result is rare.

Persons: ”, Joseph Rizzo, ” Susan Mollan, Disha, Dr, Sanjay Gupta, Chanapa, Andrew Lee, ” Narang Organizations: CNN —, Mass, Novo Nordisk, CNN, Harvard Medical School, ”, University Hospitals Birmingham, Endeavor Health, CNN Health, US Food and Drug Administration, FDA, American Academy of Ophthalmology, Houston Methodist Hospital Locations: Chicago

☆ Many people using GLP-1s for weight loss stop treatment too soon, research shows, and results are not one-size-fits-all
▼ + stars: | 2024-05-21 | by ( Deidre Mcphillips | ) edition.cnn.com time to read: +8 min

Professional organizations have set this as a guideline for when to reassess whether a treatment is providing clinically meaningful weight loss. People who met with their providers less frequently – and those living in underserved regions with broader health inequities – were more likely to discontinue GLP-1 treatment sooner. But using GLP-1 treatments are still an investment in many ways. These injected medications, called GLP-1 agonists, are in high demand because they have proved to be so effective for weight loss. And experts warn that the GLP-1 treatment process can be different for everyone.

Persons: ”, Disha, Wegovy, Jody Dushay, Beth, There’s, Razia Hashmi, ” Hashmi, it’s, “, Dr, Sanjay Gupta, ” Narang, ” Dushay Organizations: CNN, Endeavor Health, Beth Israel Deaconess Medical Center, Harvard Medical School, Shield, Dandelion Health, CNN Health, “ Locations: Chicago, –, GLP

☆ What the results of Wegovy’s longest clinical trial yet show about weight loss, side effects and heart protection
▼ + stars: | 2024-05-13 | by ( Meg Tirrell | ) edition.cnn.com time to read: +10 min

CNN —New analyses of the longest clinical trial yet of the weight-loss drug Wegovy are shedding light on how quickly it helps people lose weight, how long they sustain that weight loss and how safe the medicine is over four years of use. A previous clinical trial showed even greater average weight loss for Wegovy: about 15% on average over 68 weeks, compared with 2.4% for people who got a placebo. It was sustained for up to four yearsThe results showed that the 10% average weight loss for people using Wegovy was sustained for up to 208 weeks, or four years. Patients stayed on the medicine while they sustained the weight loss. Almost 23% of people on Wegovy lost at least 15% of their body weight, compared with 1.7% on a placebo.

Persons: Wegovy, –, ”, Harlan Krumholz, Dr, Donna Ryan, Eli Lilly, wasn’t, they’d, Daniel Drucker, it’s, John Deanfield, Krumholz, Drucker, GLP, Sanjay Gupta Organizations: CNN, Yale University, Yale New Haven Hospital, drugmaker, Nordisk, Novo Nordisk, European, Obesity, Nature, Pennington Biomedical Research, University of Toronto, University College London, CNN Health Locations: Baton Rouge , Louisiana, Novo

☆ ‘Ozempic babies’: What the science says on whether GLP-1s lead to surprise pregnancies, and their safety if they do
▼ + stars: | 2024-05-08 | by ( Mira Cheng | Meg Tirrell | ) edition.cnn.com time to read: +12 min

“I was depressed, severely depressed for that whole time.”Five months earlier, in October 2022, Bentley had started taking Mounjaro for weight loss. Ozempic uses the active ingredient semaglutide, and Wegovy is the version approved for weight loss. Mounjaro uses tirzepatide, which also targets a second hormone called GIP, and Zepbound is its brand name for weight loss. Safety in pregnancyEven as GLP-1 medicines may increase fertility, little is known about their safety during pregnancy. “It’s kind of like heart failure or sleep apnea,” he said, referring to conditions for which GLP-1 drugs have recently shown positive results.

Persons: CNN — Catera Bentley, Bentley, ”, “, ” Bentley, she’d, —, ‘, ’ Bentley, Jody Dushay, Dushay, Catera Bentley, Ivy, Daniel Drucker, ” Drucker, they’re, Drucker, Eli Lilly, ” Dushay, haven’t, That’s, Anuja Dokras, Dokras, Melanie Cree, Cree, PCOS, aren’t, Eli Lilly’s, Daniel Skovronsky, ” Skovronsky, Dr, Sanjay Gupta, it’s, Mounjaro Organizations: CNN, Beth Israel Deaconess Medical Center, Harvard Medical School, University of, Mount Sinai, Novo Nordisk, Zepbound, US Centers for Disease Control, University of Pennsylvania, PCOS, Children’s Hospital, National Institutes of Health, CNN Health Locations: Steele , Alabama, Mount, United States, Children’s Hospital Colorado, —, Colorado

☆ FTC challenges 'junk' patents held by 10 drugmakers, including for Novo Nordisk's Ozempic
▼ + stars: | 2024-04-30 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +2 min

The Federal Trade Commission on Tuesday said it is challenging hundreds of alleged "junk" patents held by pharmaceutical companies for 20 brand-name drugs, including Novo Nordisk's blockbuster drugs Ozempic, Saxenda and Victoza. The FTC issued letters to 10 companies, warning them that certain drug patents were improperly listed. Many of the drug patents are for Type 2 diabetes, along with asthma and inhalers for chronic obstructive pulmonary disease, or COPD. Generic drugmakers can only launch cheaper versions of a branded drug if the patents have expired or are successfully challenged in court. The FTC first challenged dozens of branded drug patents last fall, leading three drugmakers to comply and delist their patents with the FDA.

Persons: Novo, Boehringer, Lina Khan, Biden, drugmakers, Joe Biden's Organizations: Federal Trade Commission, FTC, Novo Nordisk, AstraZeneca, Covis Pharma, GlaxoSmithKline, Novartis, Teva Pharmaceuticals, Amphastar Pharmaceuticals, Food and Drug Administration, FDA Locations: U.S

☆ Diplomats Head to Saudi Arabia for New Talks About War in Gaza
▼ + stars: | 2024-04-28 | by ( Vivek Shankar | ) www.nytimes.com time to read: +3 min

By Saturday, the heat had significantly eased and the forecast was for more moderate temperatures in coming days. Mr. Fayyad was displaced with his wife and only daughter from Khan Younis, where they lived and owned a pharmacy. Nearly two million Palestinians in Gaza were forced to flee their homes under Israeli bombardment and military evacuation orders. Parents across the Gaza Strip are relying on water to keep their children cool when it is already not easy to get. He added: “The tent, the heat wave, and the horror of this war are all a nightmare.

Persons: ”, Mohammed Fayyad, Fayyad, Julia, Mr, Khan Younis, Mohammed Abu Hatab, “, Abu Hatab Locations: Gaza, Al

☆ Patients Hate ‘Forever’ Drugs. Is Wegovy Different?
▼ + stars: | 2024-03-24 | by ( Gina Kolata | ) www.nytimes.com time to read: +1 min

Most people, study after study shows, don’t take the medicines prescribed for them. It doesn’t matter what they are — statins, high blood pressure drugs, drugs to lower blood sugar, asthma drugs. Either patients never start taking them, or they stop. Though it’s still early days, and there is a paucity of data on compliance with the new drugs, doctors say they are noticing another astounding effect: Patients seem to take them faithfully, week in and week out. A national survey showed that when people were told they would gain weight back if they stopped taking the drugs, most lost interest in starting them.

Persons: don’t, nonadherence, Wegovy, it’s

☆ Eli Lilly taps Amazon Pharmacy to help deliver weight loss drug Zepbound, other medicines to patients
▼ + stars: | 2024-03-13 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +3 min

Eli Lilly on Wednesday said Amazon Pharmacy will help send certain prescription drugs, including the red-hot weight loss treatment Zepbound, to patients' homes through the drugmaker's new direct-to-consumer program. The website, LillyDirect, connects people with an independent telehealth company that can prescribe certain drugs if they are eligible. LillyDirect plans to expand the medicines it offers and the companies it partners with in the future, Eli Lilly said. Amazon Pharmacy offers free two-day deliveries to patients with an Amazon Prime membership, which will also apply if they use LillyDirect. But he told CNBC that Eli Lilly expects Amazon Pharmacy and Truepill to have similar processing and shipping times.

Persons: Eli Lilly, Eli Lilly's, Frank Cunningham, Cunningham, Truepill, John Love, We're, Lilly Organizations: Amazon Pharmacy, Amazon, CNBC Locations: U.S

☆ How to access the new weight loss drugs
▼ + stars: | 2024-02-15 | by ( Andrea Kane | ) edition.cnn.com time to read: +7 min

(CNN) — By now, it is pretty clear that the new weight loss and diabetes medications have achieved blockbuster status. Unlike previous weight loss medications, they are pretty effective at helping people lose weight and keep it off — between around 15% to 20% of body weight — with relatively few side effects (although some people can’t tolerate them, and a fraction of patients experience more severe side effects). Zepbound, the newly approved weight loss drug from Eli Lilly, may be easier to find. “Otherwise, some physicians are prescribing older, generic weight loss medications that can be helpful for some patients.”These drugs are not right for everyoneFor many people, the cultural pressure to look a certain way is high. And join us next week on the Chasing Life podcast when we talk to WeightWatchers CEO Sima Sistani about whether these new weight loss drugs really signal the end of diet culture.

Persons: Sanjay Gupta ”, Eli Lilly, Goldman Sachs, Meg Tirrell John Nowak “, Meg Tirrell, Sanjay Gupta, ” Tirrell, “, ” Eli Lilly, Tirrell, ”, Sima Sistani Organizations: CNN, —, Trilliant Health, Novo Nordisk, US Food and Drug Administration, “, Nordisk, ”

☆ U.S. Makes Initial Offers in Medicare Drug Price Negotiations
▼ + stars: | 2024-02-01 | by ( Noah Weiland | More About Noah Weiland | ) www.nytimes.com time to read: +2 min

Why It Matters: The price offers kick off negotiations. The initial round of price offers is a key step in the negotiation process. The price negotiation program was created by the Inflation Reduction Act, the climate, tax and health care package that President Biden signed into law in 2022. Additional medications will be chosen for price negotiations in the coming years. A federal judge in Delaware heard arguments on Wednesday in a case brought by AstraZeneca, the maker of a diabetes drug that was selected for price negotiations.

Persons: ”, Andrew W, Mulcahy, Biden, Mr, drugmakers Organizations: Biden, RAND Corporation, Medicare, U.S . Chamber, Commerce, AstraZeneca Locations: Delaware

☆ FDA finds new manufacturing lapses at Eli Lilly plant
▼ + stars: | 2024-01-19 | by ( ) www.cnbc.com time to read: +4 min

An Eli Lilly and Company pharmaceutical manufacturing plant is pictured in Branchburg, New Jersey, March 5, 2021. U.S. inspectors recently uncovered new manufacturing problems at an Eli Lilly plant that has been under scrutiny by federal investigators, according to government records obtained by Reuters. They included problems in tracking manufacturing process and quality controls, as well as lapses in its calibration of equipment and failure to properly maintain facilities and equipment, the inspection report shows. Yet the Indianapolis-based drugmaker has been cited multiple times for manufacturing problems at its U.S. plants over the last few years, Reuters has reported. Three regulatory experts who reviewed the new inspection report described the most recent lapses as serious.

Persons: Eli Lilly, Lilly, Steven Lynn, Lynn Organizations: Company, U.S, Reuters, The, The U.S . Food, Drug, FDA, U.S . Department of Justice, Justice Department, Manufacturing Locations: Branchburg , New Jersey, The U.S, Lilly's, , New Jersey, U.S, Indianapolis

COVID-19 is leading hospital admissions among the respiratory viruses, according to the U.S. Centers for Disease Control and Prevention. Last week, 25 U.S. states had high or very high levels for respiratory illnesses with fever, cough and other symptoms. Since the beginning of October, there have been at least 16 million illnesses, 180,000 hospitalizations, and 11,000 deaths from flu so far this season. With vaccination rates low, what can you do to protect yourself from respiratory viruses, including influenza, COVID-19 and RSV? That’s important to see if you need one of the medicines that can help prevent severe illness: Paxlovid for COVID-19 and Tamiflu for flu.

Persons: you’ve, Jennifer Sonney, Sonney, ” Sonney Organizations: U.S . Centers for Disease Control, CDC, HOME, University of Washington School of Nursing, National Association of Pediatric, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group, AP Locations: U.S, United States, Seattle, COVID

BAINBRIDGE, Ga. (AP) — Some local residents and an animal-rights group are protesting plans for a monkey-breeding facility in southwest Georgia. Political Cartoons View All 253 ImagesThe Bainbridge facility would provide a domestic source of monkeys to offset imports, the company said. “PETA urges Bainbridge officials to withdraw their support and shut down this project before a shovel hits the dirt," she wrote. The company and local officials said the nonprofit and community's concerns are baseless. Local officials in December agreed to property tax breaks for the project — waiving them for the first 10 years and then gradually decreasing tax breaks until they end after 20 years.

Persons: didn’t, Charles River, we’d, ” Ted Lee, Lisa Jones, Engel, ” Jones, Bainbridge, Rick McCaskill, ” McCaskill Organizations: Council, Medicine, Charles River Laboratories, PETA, Development Authority of, Local Locations: BAINBRIDGE, Ga, Georgia, Bainbridge, Cambodia, Brazoria County , Texas, Houston, U.S, Development Authority of Bainbridge & Decatur County

☆ Israel and Hamas have agreed deal on medicine for hostages, aid to Gaza, Qatar says
▼ + stars: | 2024-01-16 | by ( Tara John | ) edition.cnn.com time to read: +3 min

CNN —Qatar says it has brokered a deal between Israel and Hamas that will see medicines delivered to Israeli hostages in Gaza in exchange for the delivery of medicine and humanitarian aid to Palestinian civilians. The medications and aid will leave Doha on Wednesday and head to Egypt before being transported to Gaza, the ministry added. The medicine is destined for more than 40 hostages thought by Israel to need it, according to the official, who also said that Hamas only agreed to the deal if more medicine was sent to hospitals and Palestinians in Gaza. Throughout the war, Israel has allowed a limited amount of aid and medicines to enter Gaza but far more is needed, humanitarian groups say. The United Nations has complained that Israel has been rejecting missions to deliver supplies to northern Gaza.

Persons: Menahem Kahana, David Barnea, Cross Organizations: CNN, Hamas, “, Qatari Ministry of Foreign Affairs, Doha, Getty, of Health, UNICEF, Al, Aqsa, Prime Minister’s, International Committee, United Nations, UN Locations: Qatar, Israel, Gaza, Egypt, Israeli, AFP, British, Qatari

☆ The CEO of an A16z-backed healthcare startup is pitching a better way to save money on obesity care
▼ + stars: | 2023-12-29 | by ( ) www.businessinsider.com time to read: +8 min

Boyarsky Pratt said about 35% of Knownwell's patients come for primary care, while the rest see the company's providers for their metabolic health. They can prescribe GLP-1 drugs, but they're just one tool the company uses to treat obesity, Boyarsky Pratt said. It's also planning to partner with more health systems to help them expand access to weight care. It partners with one large system in Massachusetts now, but Boyarsky Pratt declined to disclose which one. "The data shows that the earlier patients get into a comprehensive treatment, the better for the long-term course of the disease," Boyarsky Pratt said.

Persons: —, Brooke Boyarsky Pratt, Andreessen Horowitz, Boyarsky Pratt, Knownwell, Angela Fitch, Berkadia, Fitch, Needham, Boyarsky Platt, they'd, Michael Siluk, It's Organizations: Service, Business, GLP, BMI, Medicare, Obesity Medicine Association . Obesity Medicine, University of Pennsylvania, Harvard Business School, Berkshire Hathaway, Obesity Medicine Association, Weight, Flare Capital Partners, Staff, Getty, American Academy of Pediatrics Locations: Boston, GLP, Massachusetts, Knownwell, Needham , Massachusetts, telehealth

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