The longtime political allies - both subject to U.S. sanctions - are seeking to cement economic ties by facilitating trade and investment.
"(The deals) constitute a milestone in the history of our bilateral and business ties," said Ricardo Cabrisas, Cuba's foreign trade minister, in a speech closing the forum on Friday.
Russia also provided funds, know-how and technology to restart a steel mill in Cuba to supply construction materials on the island, according to Cuba state-run media reports.
More than 150 Russian businesspeople attended the forum in Havana, according to Cuban officials.
SUGAR DEALRussia this week also promised to help revive Cuba's once-vaunted sugar industry, which has nearly collapsed in recent years as its production has plunged to historic lows.