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☆ Scientists create chimeric monkey with two sets of DNA
▼ + stars: | 2023-11-09 | by ( Katie Hunt | ) edition.cnn.com time to read: +7 min

CNN —Scientists based in China have created a monkey chimera with two sets of DNA, experimental work they say could ultimately benefit medical research and the conservation of endangered species. It’s the world’s first live birth of a primate chimera created with stem cells, the researchers said. Scientists have created mouse embryos that are part human, and in 2021, scientists reported that they had grown human-monkey chimeric embryos. In September, researchers reported that they had grown kidneys containing mostly human cells inside pig embryos. Then they selected a subset of cells to inject into genetically distinct 4- to 5-day-old embryos from the same monkey species.

Persons: —, ”, Miguel Esteban, chimeras, Zhen Liu, Liu, Jun Wu, hadn’t, Wu wasn’t, Jacob Hanna, ” Hanna, Penny Hawkins, “ Organizations: CNN —, Cell, Guangzhou Institute of Biomedicine, Chinese Academy of Sciences, Research, University of Texas Southwestern Medical Center, Weizmann Institute of Science, Royal Society for, National Academies of Sciences, Engineering, Medicine, Covid Locations: China, Health, Research Hangzhou, Israel, United States

☆ Scientists take ‘pioneering steps’ toward growing human kidneys in pigs
▼ + stars: | 2023-09-07 | by ( Katie Hunt | ) edition.cnn.com time to read: +8 min

CNN —Scientists have grown kidneys containing mostly human cells inside pig embryos, an important step toward growing kidneys and potentially other human organs that could be used for transplants in people. “The paper describes pioneering steps in a new approach to organ bioengineering using pigs as incubators for growing and cultivating human organs,” said Dusko Ilic, a professor of stem cell sciences at King’s College London, in a statement. “It is remarkable to see about 60% of the primordial pig kidney contained human cells,” Wu said. What the researchers didTo generate kidneys mostly composed of human cells in pigs, the scientists used cutting-edge techniques harnessing advances in stem cells, gene editing and embryology. “This (new) work is different from existing xenotransplantation approach and aims to generate organs mostly composed of human cells in pigs,” Wu said.

Persons: ”, Miguel Esteban, ” Esteban, “, Dusko Ilic, Jun Wu, Wu, ” Mary Garry, ” Wu, Esteban, ” Joseph A, Vassalotti, ” Vassalotti Organizations: CNN —, Guangzhou Institute of Biomedicine, Chinese Academy of Sciences, Procurement, Transplantation Network, King’s College London, University of Texas Southwestern Medical Center, University of Minnesota’s, Heart Institute, National Kidney Foundation, Icahn School of Medicine Locations: Health, United States, Mount Sinai

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