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Hospitals across the U.S. are taking steps to conserve their supplies of IV fluids after Hurricane Helene struck a critical manufacturing plant belonging to the country’s biggest supplier. IV fluids are used to deliver drugs or water with electrolytes directly into a patient’s bloodstream. Follow live updates on the aftermath of Hurricane HeleneThere are four primary manufacturers of IV fluids in the U.S. Baxter is the leader, accounting for about 60% of the market. The company is the main supplier for Mass General Brigham in Boston, which uses more than 100,000 liters of IV fluid from Baxter every month. “Patients are still getting IV fluids when they need them,” Biddinger said.
Persons: Helene, They’re, Baxter, Brigham, Dr, Paul Biddinger, Biddinger, it’s “, ” Biddinger, Organizations: Baxter International, Mass, Gatorade Locations: U.S, , North Carolina, Boston
Absolute iron deficiency can be treated with iron supplements, and functional iron deficiency is managed by treating the underlying conditions leading to it, Buckley said, adding that the long-term consequences of functional iron deficiency remain under investigation. Absolute iron deficiency was also common among older women and men, a group that may be more susceptible to the effects of iron deficiency,” he said. Even among adults without conditions that may be associated with iron deficiency – anemia, heart failure, chronic kidney disease or pregnancy – the estimated prevalence of absolute iron deficiency was 11% and that of functional iron deficiency was 15%. Only about 33% of the adults with absolute iron deficiency and 14% of adults with functional iron deficiency had a potential medical reason to screen for iron deficiency, such as anemia, heart failure, chronic kidney disease or pregnancy. However, we know that iron deficiency can cause symptoms before a patient becomes anemic, as anemia is a late-stage manifestation of iron deficiency,” he said.
Persons: Dr, Leo Buckley, Buckley, , , menstruate, Jacob Cogan, Cogan, ” Cogan, Sanjay Gupta, Theodore Strange, ” Strange Organizations: CNN, United States –, JAMA, of Pharmacy, Brigham, Women’s, Women’s Hospital, National Health, University of Minnesota, CNN Health, Northwell’s Staten Island University Hospital Locations: United States, Boston, Northwell’s
Nearly 1 in 3 Americans may have an undiagnosed iron deficiency, a problem that can lead to fatigue, brain fog and difficulty concentrating, a new study suggests. An analysis of data from more than 8,000 adults in the U.S. revealed that 14% had low iron blood levels, a condition known as absolute iron deficiency, while 15% had the right iron levels but their bodies couldn’t use the essential mineral properly, known as functional iron deficiency, according to the report published Tuesday in JAMA Network Open. Doctors don’t typically screen adults for iron deficiency, which is why the condition has been overlooked in many people. There had been hints in other studies suggesting iron deficiency might be more widespread than doctors assume. The rates of iron deficiency between men and women are more similar after the age of menopause, experts said.
Persons: don’t, , Leo Buckley, , Dr, Andrew Eisenberger, Eisenberger, ” Eisenberger, Brigham, Buckley, Johanna Contreras, Hossein Ardehali, Ardehali Organizations: Brigham, Women’s Hospital, Columbia University Vagelos College of Physicians and Surgeons, Women’s, National Health, Renal Research Institute, Molecular Cardiology, Northwestern University Feinberg School of Medicine, Research Locations: U.S, Boston, Sinai, New York City
He told Business Insider he's not anti-supplement, but takes a food-first approach to his health. "I do feel that my diet provides an adequate amount of the important nutrients in order to meet requirements and maintain my health. So I don't see a need right now for dietary supplements," Pasiakos said. PIXNIOFiber supplementPasiakos sometimes takes a fiber supplement, such as psyllium husk or inulin, when he's traveling. He's not picky about the type of protein supplement and said that whey protein, pea protein, plant protein, and even a glass of milk will suffice.
Persons: , Stefan Pasiakos, Pasiakos, there's, he's, He's Organizations: Service, National Institutes of Health, Business, Columbia University and Brigham, Women's, US Preventive Services Task Force, National Cancer Institute, Mayo Clinic
CNN —Three men’s lacrosse players at Tufts University remain hospitalized after a voluntary, supervised 45-minute workout with a Navy SEAL graduate left them with a dangerous condition called rhabdomyolysis, the university said. A spokesperson for the university previously said five remained hospitalized. All have been evaluated by medical professionals, with a total of nine requiring hospitalization for rhabdomyolysis (rhabdo),” Collins said in an updated statement Monday. “The university continues to closely monitor the condition of the team, and some individual team members have been medically cleared to resume training,” Collins said. “A typical time of year when we see it in athletes is in the off-season, or getting ramped back up,” Sikka, who also serves as a team physician for the New York Yankees, told CNN.
Persons: BUD, Patrick Collins, ” Collins, , Dr, Shruti Gupta, , Robby Sikka, ” Sikka, Sikka, it’s, CNN’s Meg Tirrell Organizations: CNN, Tufts University, SEAL, Tufts, Navy SEAL, Media Relations, Cleveland Clinic, Brigham, Women’s, WCVB, Professional Tennis Players, New York Yankees
But the latest provisional data shows that overdose deaths made a sharp turn at the end of last year and have been trending down for months. There were about 101,000 overdose deaths in the year ending in April, CDC estimates. Overdose deaths involving fentanyl and other synthetic opioids are down 20% year-over-year, CDC data shows. These drugs are now involved in about two-thirds of all fatal overdoses, down from more than three-quarters of all overdose deaths a year ago. “We’ve been riding a better than 20-year peak in terms of the continuous increases of drug overdoses,” Pamplin said.
Persons: , Sarah Wakeman, Brigham, , Nabarun Dasgupta, Dasgupta, it’s, ” Wakeman, ” John Pamplin, “ We’ve, ” Pamplin, ” Dasgupta, Dr, Sanjay Gupta, Nora Volkow Organizations: CNN, Federal, US Centers for Disease Control, Mass, University of North, CDC, United States, Columbia University, CNN Health, Black, National Institute on Drug, National Institutes of Health Locations: United States, University of North Carolina, United
Taking a high dose of ADHD drugs is linked to more than five times greater risk of developing psychosis or mania, according to a new study published Thursday in the American Journal of Psychiatry. The research is among the first to find a relationship between escalating doses of the drugs — amphetamines, in particular — and a greater likelihood of psychotic symptoms. The drugs include Adderall, Vyvanse and generic amphetamines, such as dextroamphetamine. The medium dosage — 20 mg to 40 mg of Adderall, 50 mg to 100 mg of Vyvanse or 15 mg to 30 mg of dextroamphetamine — was linked to a 3.5 times higher risk. There was no increased risk of psychosis with another ADHD drug, Ritalin, which isn’t an amphetamine.
Persons: it’s, , Jacob Ballon, hadn’t, Will Cronenwett, ” Cronenwett, Vyvanse, Takeda, Lauren Moran, Brigham, , ” Moran, Moran, Cronenwett, ” Ballon, they’re Organizations: American, of Psychiatry, Stanford Medicine, Northwestern Medicine, Psychiatry, NBC News, Takeda Pharmaceuticals, . Food, Drug Administration, FDA, Pharmaceuticals, McLean Hospital, Mass Locations: United States, U.S, Boston
But it's fellow influencer Jen Affleck's relationship with her husband, Zac Affleck, that show has caught fans' attention. Here's what to know about Zac and Jen Affleck and their relationship. Zac and Jen met when she was 18 and they got married a year laterJen said she met Zac on a dating app called Mutual in 2018 when she was 18 and he was 21. Jen said last week during an interview with People that Zac was only a "distant relative" and the couple had never met Ben or Casey Affleck. AdvertisementJen auditioned to be part of 'The Secret Lives of Mormon Wives' before joining Mormon MomTokIn the "Weekly Trash" podcast episode, Jen said she wasn't affiliated with Mormon MomTok before the show started filming.
Persons: , Ben, Casey Affleck, Taylor Frankie Paul, Jen Affleck's, Zac Affleck, Zac, Jen, Jen Affleck, Maria, Jen's, Rick, Nora Affleck, Lucas Lowell Affleck, Ben Affleck, Jennifer Lopez, Monica Schipper, I'm, Arizona Jen Organizations: Service, Hulu, Business, Brigham Young University, Brigham Young University in, Mormon, TikTok Locations: Las Vegas, Utah, Ecuador, Brigham Young University in Utah, Northern California, Salt Lake City, Arizona
The DOJ did not name Tenet Media but NBC News identified the company based on its description in the indictment. Unlike the influencers alleged to have been victims of RT and Tenet Media, who denied knowing they were working for Russia, Chen has said nothing since the indictment made news. “By connecting to and interacting with one another through YouTube videos, influencers with mainstream audiences lend their credibility to openly white nationalist and other extremist content creators,” Lewis wrote. Following the unsealing of the indictment, TheBlaze fired Chen and Turning Point USA removed her author page from its website. YouTube terminated all four of Chen’s pages, erasing thousands of videos and nearly a decade of work, including the channel for Tenet Media.
Persons: Lauren Chen, Chen, Liam Donovan, Candace, Jason Davis, Dave Rubin, Tim Pool, Benny Johnson, Lauren Southern, — Chen, , Michael Knowles gushed, Richard Spencer, ” Knowles, Tenet, Milo Yiannopoulos, ” Yiannopoulos, she’s, Yiannopoulos, Spencer, Rebecca Lewis, Ben Shapiro, Lewis ’, ” Lewis, Evie, Mark Levin, Michelle Malkin, Glenn Beck’s TheBlaze, TheBlaze, , Fuentes’s, Nikki Haley “, Matt Christiansen, Donovan “ Organizations: Department of Justice, DOJ, NBC News, Tenet Media, Trump, RT, Getty, YouTube, Tenet, University of Southern, College Republicans, Brigham Young University, Facebook, Southern Poverty Law Center, Data & Society, , , Scouting, United Nations Locations: Russian, Russia, Nashville, Tenn, Southern, Canadian, Shanghai, Singapore, London, , University of Southern California, Charlottesville , Virginia, Stanford, Israel, Gaza, Ukraine
PARIS — Former college hoops star and NBA veteran Jimmer Fredette tore ligaments playing for Team USA's 3x3 Olympics team and will be sidelined for about six months, he revealed late Sunday on social media. The Americans didn't get out of group play and suffered a tournament-ending 21-6 loss to the Netherlands, landing them in seventh place among eight squads. Fredette said he tore two ligaments in his adductor in his second game in Paris, a loss to Poland. The U.S. 3x3 team finished second in last year's 3x3 World Cup, dropping a 21-19 decision to Serbia in the title game. And Fredette was just ranked the top 3x3 player in the world by the International Basketball Federation), the governing body of basketball.
Persons: Jimmer Fredette, didn't, Fredette, Carolina Marin, , ” Fredette, he'd, Organizations: PARIS —, USA's, Carolina, Tokyo Games, International Basketball Federation, Brigham Young University —, NBA Locations: Netherlands, Paris, Poland, France, China, Spanish, U.S, The U.S, Serbia
During the pandemic, they moved to Colorado Springs, where they opened the city's first gay cocktail bar, ICONS. Josh: I was born and raised in Colorado Springs, but I moved to New York at the age of 22. We could feel the energy growing in Colorado Springs, so we figured it was a smart move. If you told teenage me that a gay bar would be voted best bar in Colorado Springs, I would have said you were crazy. We love, love, love it.
Persons: , John Wolfe, Josh Franklin, Josh, John, COVID, it's, It's, pushback Josh, I've, Josh Franklin Colorado, Coutesy, We're, I'm, we'll Organizations: Service, Broadway, Business, Brigham Young University, Mormon, Colorado Springs, Denver Locations: New York City, Colorado Springs, New York, West Virginia, Connecticut, Colorado, John, It's
She was talking about NAD+ boosters — the antiaging elixirs that have joined the ranks of Ozempic and Botox as staples of elite wellness routines. Even the military is testing out NAD boosters, hoping they might someday rejuvenate soldiers on the battlefield. "NAD coenzymes are the central catalysts of all living things," Charles Brenner, a biochemist who studies NAD, told Business Insider. AdvertisementTo boost NAD, don't take NADThere is a plethora of various powders, pills, and IV drips all promising to boost NAD. How to boost your NAD without an IV dripChicken, fish, and edamame all help boost our NAD levels.
Persons: , I'm, Hailey Bieber, Joe Rogan, Stephane Cardinale, Charles Brenner, Robert Fried, Brenner, Fried, Dr, Sabine Donnai, She's, Shin, ichiro Imai, Louis who's, nicotinamide, Jeffrey Coolidge, pricey, Donnai, We're, Kourtney Kardashian, Arturo Holmes, Shalender Bhasin, hasn't Organizations: Service, Ozempic, Business, Hollywood, US Food and Drug Administration, Images Nutrition, Washington University School of Medicine, NAM, Brigham, Women's Hospital Locations: London, St, Boston
The risk for dementia dropped by 20%, however, for people who replaced that small daily serving of processed red meat with a daily serving of nuts and legumes. Processed red meats such as bacon, sausage, hot dogs and deli meats often contain higher levels of sodium, nitrates and saturated fat. Each additional serving of processed red meat raised riskAn abstract of the study, which is under review for publication, was presented Wednesday at the 2024 Alzheimer’s Association International Conference in Philadelphia. Red meat intake is limited. Red meat, especially processed red meat as seen here, is linked to an unhealthy heart and brain.
Persons: , Walter Willett, ” Willett, David Katz, Katz, Maria Carrillo, Tanja Ivanova, Yuhan Li, Li, Christopher Gardner, ” Gardner, chia, sprinkle chia Organizations: CNN, Harvard, of Public Health, True Health Initiative, International Conference, Nurses, Alzheimer’s Association, Getty, Division, Network Medicine, Brigham, Women’s Hospital, Stanford Prevention Research, Nutrition Studies Research Locations: Chan, Boston, Philadelphia, bologna, lima, California
CNN —Four days after a faulty software update from a cybersecurity company unexpectedly brought down computers and technical systems across the world, airlines and some other companies are still experiencing delays and other technical problems. The outage was related to a software update rolled out by CrowdStrike, a major US cybersecurity firm. The issue is specific to Falcon, one of CrowdStrike’s main software products, and is not impacting Mac or Linux operating systems, according to the advisory. US-based carriers American Airlines, United Airlines, Delta Air Lines, Allegiant Airlines, SunCountry and Frontier Airlines all reported issues on Friday. More than 1,200 Delta flights were canceled on Sunday, after the carrier canceled 1,208 flights on Saturday, according to FlightAware.
Persons: ” –, Patrick Anderson, , CrowdStrike, , George Kurtz, Kurtz, Crowdstrike, United, Delta, Pete Buttigieg, Ed Bastian, ” Buttigieg, Bastian, it’s, David Kennedy, “ It’s, ” Kennedy, “ There’s, Buttigieg, Brigham, Dana Organizations: CNN, Microsoft, Anderson Economic Group, Fortune, Travelers, Marriott International, American Airlines, United Airlines, Delta Air Lines, Allegiant Airlines, Frontier Airlines, Delta Airlines, Delta, Delta Air, Department, Turkish Airlines, Jetstar, Hong Kong Express, Cebu Pacific, Binary Defense, Mass, Penn Medicine, Mount, Mount Sinai Health, Emory Healthcare, Farber Cancer Institute, New, Memorial Sloan Kettering Cancer Center, Government, Social Security, Department of Motor Vehicles, UPS, FedEx Locations: Delta, FlightAware, Jetstar Japan, Hong, Massachusetts, Pennsylvania, Mount Sinai, New York, Atlanta, Boston, Arizona, Alaska, Washington ,
Timeline: How the CrowdStrike outage unfolded
  + stars: | 2024-07-20 | by ( Eva Rothenberg | ) edition.cnn.com   time to read: +10 min
Washington, DC, public transportation services — including trains and buses — begin experiencing delays, according to the Washington Metropolitan Area Transit Authority. At 5:30 a.m., US cybersecurity firm CrowdStrike tells customers that it was “aware of reports of crashes” of its software on Microsoft Windows operating systems, according to a company advisory viewed by CNN. Australian lenders ANZ and Westpac were also impacted, according to Downdetector, a website that tracks cyber outages. Other states also report impacts to their driving services, including Georgia, North Carolina, Texas and Tennessee. CrowdStrike would take steps “to prevent anything like this from happening again,” according to a statement on the company’s website.
Persons: Ted Wheeler, they’re, We’re, Charlotte, Biden, Joe Biden, George Kurtz, , Brigham, Dana, Blood, Andrea Cefarelli, Jenny Ficenec, , Kurtz, CrowdStrike Organizations: New, New York CNN, Federal Aviation Administration, American Airlines, FAA, Allegiant Airlines, Spirit Airlines, Washington Metropolitan Area Transit Authority, Metropolitan Transportation Authority, Microsoft, CNN, CrowdStrike’s, Fortune, White, National Security, Global, Australia’s Commonwealth Bank, Bank of Israel, ANZ, Westpac, ASB Bank . Portland, Emergency, Dispatch, United Airlines, Air Lines, Hartsfield Jackson International, Charlotte Douglas International Airport, , Miami International Airport, Customs, Border, Alaska State Troopers, Phoenix Police Department, Computer, Police, Rescue, Federal Communications Commission, US Department of Homeland Security, CrowdStrike, Social, US Department of Justice, UPS, FedEx, Massachusetts Department of Transportation, Vehicle, Mass, Penn Medicine, Northwell, Emory Healthcare, Farber Cancer Institute, Memorial Sloan Kettering Cancer Center, Provincial Health Services Authority, New York Blood Center, Northeast, Centers of America, Assurance Locations: New York, Alaska, Arizona, Delta, United, Washington, DC, New York City, North, Georgia, North Carolina , Texas, Tennessee, Massachusetts, Pennsylvania, Atlanta, Boston, British Columbia, New, Northeast United States, North Carolina, Virginia
The Surprising Power of Texting a Friend
  + stars: | 2024-06-09 | by ( Catherine Pearson | ) www.nytimes.com   time to read: +1 min
I’m Catherine Pearson, and I cover families and relationships for The New York Times. Today, I’m making the case for something many of us have a love-hate relationship with: texting. It was from Miranda, a high-school friend whom I catch up with only a couple of times a year. Ample research shows that social connection is crucial to our physical and mental health and longevity. One oft-quoted 2010 study concluded that lacking social connection might be comparable to smoking up to 15 cigarettes a day.
Persons: I’m Catherine Pearson, Miranda, Julianne Holt, , You’re, Organizations: The New York Times, Social Connection, Health, Brigham Young University
So he did just that, working slightly fewer hours but maintaining a strong balance between work, family, and hobbies. It's all part of his "life happiness index" that drives his financial and life decisions. Some wanted to resume their past jobs, while others looked to lower-stress roles like nonprofit or charity work. He keeps track of a "life happiness index," which he said is highest when he balances his work with family and hobbies. When considering his "final" retirement, he said he plans to work as long as he enjoys it.
Persons: Jace Mattinson, Mattinson, , wasn't, He's, I've, he's Organizations: Service, Business, Dallas, Brigham Young University Locations: PwC, Dallas, Austin, Texas, Oklahoma
CNN —Women who closely followed a Mediterranean diet lived much longer than those who did not, according to a new study that followed more than 25,000 women for 25 years. “In this study, adherence to the Mediterranean diet was a proxy for diet quality. Each increase in the adherence to the Mediterranean diet extended life for women, the new study found. In all that data, however, are few details on the specific ways the Mediterranean diet may affect women, especially long-term. “What might be worth noting is that the adherence measure ‘corrects’ for distortions of the Mediterranean diet,” Katz said.
Persons: CNN —, , Samia Mora, David Katz, Katz, ” Katz, It’s, Shafqat Ahmad, Ahmad, Organizations: CNN, Brigham, Women’s Hospital, Harvard Medical School, True Health Initiative, JAMA, Uppsala University Locations: Boston, Sweden
A new generative AI tool can create those studies in minutes. That directive informed Atropos' development of ChatRWD, which Atropos Health launched in beta form in October to 75 customers. Atropos says it's the first generative AI tool to create publication-grade studies from clinical data in minutes. AdvertisementAtropos' $33 million Series B funding follows Atropos' $14 million Series A in August 2022, bringing the company's total funding to $54 million. See the 22-slide pitch deck Atropos Health used to raise $33 million in Series B funding.
Persons: , Brigham Hyde, Valtruis, Jim Breyer's Breyer, Laurene Powell Jobs, Nigam Shah, Saurabh, Hyde, Atropos, Green Button, Green, Johnson, Johnson's Janssen Organizations: Service, Business, Atropos, Cencora Ventures, McKesson Ventures, Merck GHI Fund, Presidio Ventures, Stanford University, National Institutes of Health, Atropos Health, pharma Locations: Geneva, Arcadia
A generic high blood pressure drug has become the most commonly prescribed oral medication to treat acne in women, overtaking antibiotics and birth control pills, a new report from Epic Research shows. Prescriptions for oral antibiotics — previously the go-to pill for acne — decreased from 41% to 27% in the same time period. While the drug was approved as a high blood pressure medication in 1960, it was in the 1980s that some doctors began prescribing it to women for acne. Birth control pills can also be an effective treatment for this type of acne, and indeed, can be prescribed by dermatologists for this reason. However, prescriptions of birth control for acne also fell from 2017 to 2023, Epic Research found.
Persons: spironolactone, John Barbieri, epidemiologist, Barbieri, “ There’s, ” Barbieri, Jessica Krant, ” Krant, Patricia Oyetakin, , Oyetakin, , dermatologists, Krant, Deborah Bartz Organizations: Epic Research, NBC, American Academy of, Brigham, Women’s Hospital, Surgery, New, Research, Women’s Locations: Boston, New York, Atlanta
All three diets are plant-based, focused on consuming more fruits and vegetables, whole grains, beans and seeds while limiting sugar, red meat and ultraprocessed foods. Eating more ultraprocessed foods such as hot dogs is linked to a higher risk of stroke and cognitive decline, according to a new study. What is it about ultraprocessed foods that may allow them to sabotage efforts to follow a healthy diet? Growing dangers of ultraprocessed foodsStudies on the dangers of eating ultraprocessed foods are piling up. That 10% increase was considered “baseline,” and adding even more ultraprocessed foods might increase the risk, experts say.
Persons: , Andrew Freeman, ’ ”, Dr, W, Taylor Kimberly, Kimberly, Peipei Gao, Zhendong Mei, Mei, Gao, Harvard T.H, ’ ” Freeman Organizations: CNN, Jewish Health, Whites, Blacks, Massachusetts General Hospital, Brigham, Women’s Hospital, Harvard, of Public Health Locations: Denver, Massachusetts, Boston, Chan
The woman in the video looks resolute, and a little sad, as she cuts up a pack of birth control pills. “These silly little pills have literally ruined me as a person,” reads the caption. Anecdotal reports from news outlets have suggested that women are quitting the pill in large numbers because of this type of online post. But, according to initial data, prescriptions for the birth control pill are not actually declining at all. Even among those aged 15 to 34, who would be most likely to see negative social media posts, Trilliant found prescriptions had increased.
Persons: , , Deborah Bartz, Trilliant Organizations: Brigham, Women’s, Trilliant Health Locations: United States
Heart disease, diabetes and kidney disease are among the most common chronic illnesses in the United States — and they’re all closely connected. Adults with diabetes are twice as likely to have heart disease or a stroke compared with those who don’t have diabetes. People with diabetes — Type 1 and Type 2 — are also at risk of developing kidney disease. And when the kidneys don’t work well, a person’s heart has to work even harder to pump blood to them, which can then lead to heart disease. syndrome, meaning they have been diagnosed with diabetes, heart disease or kidney disease or are at high risk of developing them, the numbers are still “astronomically higher than expected” said Dr. Rahul Aggarwal, a cardiology fellow at Brigham and Women’s Hospital in Boston and co-author of the study.
Persons: , Rahul Aggarwal Organizations: American Heart Association, Brigham, Women’s Hospital Locations: United States, Boston
“Now, post-surgery and post recovery, I am able to see in dimmer lighting with my left eye,” Cook said. A treatment that used CRISPR was found to be safe and efficacious in improving vision among a small sample of patients with inherited blindness in the Phase 1/2 clinical trial that Cook participated in. Months following the treatment, Cook was sitting with friends on a balcony that had Christmas lights wrapped around the railing. Courtesy Olivia CookBefore the treatment, Cook said that she sometimes could conceal the vision challenges she has had. Mass Eye and EarKalberer described the CRISPR treatment as “groundbreaking,” but warned it’s not a cure.
Persons: Olivia Cook, Cook, , ” Cook, , I’ve, “ I’d, you’d, CRISPR, Eric Pierce, Brigham, “ We’re, ” Pierce, Jason Comander, , Michael Kalberer, Kalberer, it’s, “ It’s, It’s, Pierce, Editas, We’re, Art Caplan, ” Caplan, , Vlad Diaconita, ” Diaconita, Dr, Sanjay Gupta, Aliaa Abdelhakim Organizations: CNN, Missouri State University, New England, of Medicine, Mass, Harvard Medical School, Editas Medicine, Perelman School of Medicine, University of Pennsylvania, University of Michigan, University of Miami, Oregon Health & Science University, US Food and Drug Administration, CEP290, pharma, NYU Grossman School, Medicine’s Department of Population Health, Columbia University Vagelos College of Physicians and Surgeons, CNN Health Locations: Springfield, United States, CEP290
Among people diagnosed with Alzheimer’s, researchers recognize familial forms of the disease and sporadic cases. This shifting appreciation of inherited risk, researchers say, is due to a better understanding of the role of a fourth gene that carries the blueprints to make a lipid-carrying protein called apolipoprotein E, known as APOE. One known as APOE2 is thought to be protective against the development of Alzheimer’s disease. They also compared people with two copies of APOE4 to people with other inherited forms of the disease — early-onset autosomal dominant Alzheimer’s disease (ADAD) and Down syndrome-associated Alzheimer’s disease (DSAD). Gene testing isn’t currently recommendedIt is also likely to change how people who carry the APOE4 gene are diagnosed and treated.
Persons: APOE4, , Dr, Juan Fortea, Sant, Fortea, Charles Bernick, Bernick, Alzheimer’s wasn’t, isn’t, they’re, ” Fortea, Sanjay Gupta, Reisa Sperling, , ” Sperling, ” Dr, Sterling Johnson, Johnson Organizations: CNN, Nature, National Alzheimer’s Coordinating, Neurology, Hospital de, Cleveland Clinic Lou, Brain Health, CNN Health, Alzheimer’s Research, Brigham, Women’s, Alzheimer’s, University of Wisconsin Locations: Alzheimer’s, Spain, United States, Santa, Barcelona, Wisconsin
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