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In other words, I may find spicy food overwhelming simply because I expect it to be. “Some of it could be expectations, but some could also be how you’re biologically wired to experience food,” Albers said. Remember expectations can significantly influence your experience.”Listen to your body: As you eat spicy food, check in with your body’s responses. “There’s no ‘right’ level of spiciness — it’s about what feels good to you.”Pair spicy foods thoughtfully: Consider balancing spicy flavors with cooling elements, such as a piece of cheese or bread. “Spicy foods can increase your metabolism, your heart rate, cause vomiting and gastric distress, so there is definitely a physiological response that’s going on,” Albers said.
Persons: , , I’m, “ There’s, Susan Albers, Oscar Wong, Yi Luo, ” Luo, ” Albers, Albers, it’s Organizations: CNN, Spice Girls, Cleveland Clinic, Getty, PLOS Biology, East China Normal University Locations: Ohio, Shanghai, Carolina
How pregnancy changes the brain
  + stars: | 2024-09-16 | by ( Kristen Rogers | ) edition.cnn.com   time to read: +8 min
CNN —Researchers have created one of the first comprehensive maps of how the brain changes throughout pregnancy, substantially improving upon understanding of an understudied field. What brain changes mean for parentsThe functional implications these brain changes may have for birthing parents have yet to be determined, said Dr. Elseline Hoekzema, head of the Pregnancy and the Brain Lab at Amsterdam University Medical Center, via email. However, some of Hoekzema’s previous work has indicated associations between pregnancy-related brain changes and the ways a birthing parent’s brain and body respond and bond to infants’ cues, Hoekzema added. These findings are also in line with animal studies showing brain changes that were critical for the onset and continuation of maternal care. “Of the 50,000 brain imaging articles published in the last 30 years, less than half of 1% focus on health factors unique to women, like pregnancy.
Persons: Elizabeth R, Chrastil, , Emily Jacobs, ” Jacobs, Jacobs, Jodi Pawluski, Pawluski wasn’t, Magdalena Martínez García, wasn’t, Elseline Hoekzema, Hoekzema wasn’t, Hoekzema, ” Pawluski, , ” Hoekzema, Pawluski, haven’t, Ann S, Bowers, Chan Zuckerberg, we’ve Organizations: CNN —, Neuroscience, University of California, UC Santa Barbara, Jacobs Lab, Amsterdam University Medical Center, Brain Health Initiative Locations: Santa Barbara, France, Spain
Tracey Tee founded Moms on Mushrooms, a platform where moms can discuss, both online and in person, their interest and experiences with microdosing psilocybin mushrooms. "Some girlfriends invited me to a camping trip that summer [in 2020] to just camp out with some moms," Tee says. She lives in Colorado where psilocybin mushrooms are legal to grow, use and share. So, Tee sought out an alternative solution for managing her mental health as she began to wean herself off the SSRI: microdosing psilocybin mushrooms. Moms on Mushrooms is the platform Tee created for moms to discuss their interest and experiences with psilocybin mushrooms.
Persons: Tracey Tee, Tee, that's, wean, Tee wasn't, Microdosing, microdosing, Louis, Joshua Siegel, Siegel Organizations: Lancet, Facebook, CNBC, Washington University School of Medicine, Washington University, NYU Langone Health, Center, Psychedelic Medicine, Psychedelic Locations: Colorado, St
Today, a group of dementia researchers from the UK released some early results that suggest it's possible these trendy injections might also stall the progression of dementia. A daily injection for brain preservationIuliia Burmistrova/Getty ImagesFor the study, researchers spent a year tracking brain changes across 204 Alzheimer's patients with mild to moderate disease. "It sounds like it is worth pursuing a larger trial, but these results cannot demonstrate that liraglutide can protect against dementia." Experts have seen how dementia patients' brains get worse and worse at efficiently using glucose for energy as their disease progresses, but the calculus is always complicated. Bigger studies using more powerful GLP-1 drugs for dementia are already ongoing.
Persons: Stephen Evans, Jason Kirk, Quynh Nguyen, hadn't, Dr, Paul Edison, it's, Edison, Alzheimer's Organizations: Service, Alzheimer's Association International Conference, London School of Hygiene, Medicine, Science Media, Nikon, Imperial College London, Food and Drug Administration, Novo Nordisk Locations: Philadelphia, Novo
Today, a group of dementia researchers from the UK released some early results that suggest it's possible these trendy injections might also stall the progression of dementia. A daily injection for brain preservationIuliia Burmistrova/Getty ImagesFor the study, researchers spent a year tracking brain changes across 204 Alzheimer's patients with mild to moderate disease. "It sounds like it is worth pursuing a larger trial, but these results cannot demonstrate that liraglutide can protect against dementia." Experts have seen how dementia patients' brains get worse and worse at efficiently using glucose for energy as their disease progresses, but the calculus is always complicated. Bigger studies using more powerful GLP-1 drugs for dementia are already ongoing.
Persons: Stephen Evans, Jason Kirk, Quynh Nguyen, hadn't, Dr, Paul Edison, it's, Edison, Alzheimer's Organizations: Service, Alzheimer's Association International Conference, London School of Hygiene, Medicine, Science Media, Nikon, Imperial College London, Food and Drug Administration, Novo Nordisk Locations: Philadelphia, Novo
CNN —Sex and gender are often conflated or equated in everyday conversations, and most American adults believe a person’s gender is determined by sex assigned at birth. But a new study of nearly 5,000 9- and 10-year-olds found that sex and gender map onto largely distinct parts of the brain. The researchers on the new study defined sex as what was assigned to the child at birth. They also hope to see how different cultures affect a person’s gender and their brain development. The study did not look at whether sex or gender were congruent or incongruent in any study participant.
Persons: , Elvisha, Dr, Dani S, Bassett, , ” Bassett, ” Dhamala, , Sanjay Gupta, Avram Holmes, Holmes, “ It’s, ” Holmes Organizations: CNN, Feinstein Institutes for Medical Research, Zucker Hillside, University of Pennsylvania, Bioengineering, Systems Engineering, Physics, Astronomy, Neurology, Psychiatry, Research, London, Conservative, CNN Health, Rutgers University Locations: Glen Oaks , California, United States
CNN —President Joe Biden said Friday that his poor performance in last week’s debate was a bad night but not evidence of a serious condition. When asked on Friday whether he’s had cognitive tests and an exam by a neurologist, Biden said no. Biden gave no indication he would be willing to have such tests conducted in the aftermath of his debate performance. “So, again, pretty important for a job like president,” Ranganath added. “Part of those evaluations will look at the overall health of the individual, from neurologic health to also cognitive health,” she said.
Persons: Joe Biden, ” Biden, George Stephanopoulos, , “ you’re, , Sanjay Gupta, ” Gupta, he’s, Biden, , Charan Ranganath, — doesn’t, “ It’s, ” Ranganath, John Rowe, , Rowe, ” Rowe, Donald Trump, aced, they’ll, Emily Rogalski, ” Rogalski, what’s, Brad Dickerson, Dickerson, ” Dickerson, Dr, Ranganath, Nadia Kounang, John Bonifield Organizations: CNN, ABC News, University of California, Columbia University, Mini, University of Chicago’s, Alzheimer’s Research Care, Harvard Medical School, Massachusetts General Hospital, Aetna, Mount, Mount Sinai NYU Health, Get CNN, CNN Health Locations: Davis, Montreal, Massachusetts, Mount Sinai
The Youngest Pandemic Children Are Now in School, and StrugglingThe pandemic’s babies, toddlers and preschoolers are now school-age, and the impact on them is becoming increasingly clear: Many are showing signs of being academically and developmentally behind. But the impact on the youngest children is in some ways surprising: They were not in formal school when the pandemic began, and at an age when children spend a lot of time at home anyway. Researchers said several aspects of the pandemic affected young children — parental stress, less exposure to people, lower preschool attendance, more time on screens and less time playing. The youngest students’ performance is “in stark contrast” to older elementary school children, who have caught up much more, the researchers said. Sarrah Hovis, a preschool teacher in Roseville, Mich., has seen plenty of the pandemic’s impact in her classroom.
Persons: ” “, , , Jaime Peterson, , Joel Ryan, Kristen Huff, Catherine Monk, ” David Feldman, Tommy Sheridan, don’t, Michaela Frederick, She’s, weren’t, Aaron Hardin, Frederick, Lissa O’Rourke, Sarrah, ” Terrance Anfield, children’s, Rahil, Briggs, Zero, Kelsey Schnur, Finley, Schnur, Analilia Sanchez, lockdowns, Heidi Tringali, Travis Dove, Tringali, I’m, Michael LoMedico, Emily Sampley, It’s, Dani Dumitriu Organizations: , Oregon Health, Science University, Curriculum Associates, Columbia, Start, Brook Allen, The New York Times, Associates, Cincinnati Public Schools, Cincinnati Children’s Hospital, The New York Locations: School, Washington State, U.S, St, Petersburg, Fla, Martin , Tenn, Sharon, Tenn, Augustine, Cincinnati, Roseville, Mich, , Indianapolis, Sharpsville, Pa, El Paso, Charlotte, N.C, Yonkers, N.Y, Sioux Falls, S.D, Tennessee, Oregon
CNN —With another pricey Alzheimer’s disease treatment expected to receive an approval decision soon, the nonprofit Alzheimer’s Association has published the final version of its new diagnostic criteria for the disease. Together with another protein, tau, which makes fibrous tangles that block the communication of nerve cells, they are considered a hallmark of Alzheimer’s disease. “There’s no evidence for it,” said Dr. George Perry, a neurobiologist and editor of the Journal of Alzheimer’s Disease. Two members of the panel were employees of the Alzheimer’s Association, which also takes funding from pharmaceutical companies. Widera says he hopes that in the next round of guidelines, the Alzheimer’s Association will consider the risks involved.
Persons: There’s, , donanemab, , , George Perry, Adriane Fugh, Berman, haven’t, Maria C, Carrillo, Alzheimer’s, It’s, Eric Widera, Widera, it’s, Aduhelm, Karl Herrup, Clifford Jack, ” Jack, “ It’s, Niles Franz, ” Franz, Dr, Sanjay Gupta, Franz, ” Widera Organizations: CNN, Alzheimer’s Association, Food and Drug Administration, FDA, Georgetown University, University of California San, American Geriatrics Society, Abbott Labs, University of Pittsburgh School of Medicine, Mayo Clinic, Nature Medicine, federal National Institute, Aging, Alzheimer’s Association International, National Institute, National Institutes of Health, NIA, Alzheimer’s, National Academy of Medicine, CNN Health, Association Locations: University of California San Francisco
6 types of depression identified in Stanford study
  + stars: | 2024-06-20 | by ( Kristen Rogers | ) edition.cnn.com   time to read: +11 min
Some 30% to 40% of people with depression do not experience symptom improvement after trying one treatment, according to the study. And about 30% of people diagnosed with depression go on to experience treatment-resistant depression when the disorder doesn’t improve after multiple treatment attempts. Mapping depression in the brainThe authors used data from 801 adult participants who were previously diagnosed with depression or anxiety, and 137 healthy control group participants. The grant supports a five-year project involving 4,500 participants, which is centered on the development of a better diagnosis and treatment tool for depression biotypes. This method isn’t intended to replace or be the primary choice for assessments of individual cases of depression, Williams said.
Persons: biotypes, , Leanne Williams, Vincent V.C, Woo, Williams, Anhedonia, Jun Ma, Ma, Beth, George Vitoux, , Richard Keefe, wasn’t, Keefe, Jonathan Alpert, Dorothy, Marty Silverman, Alpert, ” Keefe, you’re Organizations: Lifeline, CNN, Nature Medicine, Psychiatry, Behavioral Sciences, Stanford University School of Medicine, Stanford Center, Precision Mental Health, Wellness, Medicine, University of Illinois, Duke University Medical Center, Montefiore Medical, Albert Einstein College of Medicine, Psychiatric Association’s Council, Research, National Institute of Mental Health, National Institutes, Health’s, Mental Health Initiative Locations: California, United States, University of Illinois Chicago, North Carolina, New York City, Stanford
“I understand concepts, I comprehend things, I have memories, but they aren’t supported by any images,” Wathen said. Paul BokslagDutch-born artist Geraldine van Heemstra is at the opposite end of this unique way of processing. In reaction to cruel teasing from her brothers and school friends, van Heemstra learned to hide her sensory abilities as a child. “It was quite tricky at school as well, such as with math, where I would see the numbers in color,” van Heemstra said. “It was so frustrating at school because I would explain something, and then I would be laughed at,” van Heemstra said.
Persons: Mary Wathen, ” Wathen, , Wathen, , “ I’ve, ‘ You’ve, Geraldine van Heemstra, Paul Bokslag Dutch, van, ” van Heemstra, “ It’s, van Heemstra, van Heemstra can’t, aphantasia, Adam Zeman, Zeman, ” Zeman, aphantasia don’t, ” That’s, I’m, they’ve, that’s, what’s, Van Heemstra, ” Van Heemstra, you’re Organizations: CNN, University of Exeter, University of Edinburgh, Cognitive Sciences, Locations: Newent, England, Scottish, London, Edinburgh, Scotland, Miami
Read previewAxel Bouchon cofounded Matter Neuroscience in 2019 after leading the venture arms of pharma giants Moderna and Bayer. AdvertisementMatter has emerged from stealth with $26 million from ARCH Venture Partners, Polaris Partners, Exor Ventures, and Collaborative Fund, Business Insider has learned exclusively. That $26 million includes an initial seed round led by Polaris Partners and a Series A round led by ARCH Venture Partners. The startup views itself now as a consumer biotech startup, Bouchon said. Here's the 17-slide pitch deck Matter used to raise $26 million.
Persons: , Axel Bouchon, Bouchon Organizations: Service, pharma, Moderna, Bayer, Business, Venture Partners, Polaris Partners, Exor Ventures, Fund, Brain Imaging, Icahn School of Medicine Locations: Maastricht, Netherlands, Mount Sinai, Seoul, South Korea
How we change as we ageA decline in cognitive abilities is a normal part of healthy aging, said Dr. Emily Rogalski, Rosalind Franklin Professor of Neurology at the University of Chicago. A diagnosis of mild cognitive impairment is made clinically when cognitive difficulties become frequent and fall outside what is considered normal aging. “There’s not a whole lot of good evidence that there’s anything special about age 80 that leads to a drop-off” in cognitive abilities, Mather said. And they use cognitive tests, such as the Mini Mental Status Exam (MMSE) or Montreal Cognitive Assessment (MOCA), to assess performance in different cognitive areas. Although population-level data associates aging with cognitive decline, the actual manifestation of aging is very diverse on an individual level, Rogalski said.
Persons: Joe Biden, Donald Trump, Biden, Trump, Nikki Haley, Nancy Pelosi, Emily Rogalski, Rosalind Franklin, , Molly Mather, , Angela Roberts, Roberts, “ There’s, Mather, MMSE, We’re, ” Mather, Nir Barzilai, Rogalski, “ We’ve, superagers, Barzilai, “ It’s, Dr, Sanjay Gupta, ” Roberts Organizations: CNN, House, Republican, NBC, Neurology, University of Chicago, UCSF, Aging, Northwestern University’s Feinberg School of Medicine, National Institute, Western University, Institute for Aging Research, Albert Einstein College of Medicine, American Federation for Aging Research, Trump, Biden, Get CNN, CNN Health, Locations: Mexico, Egypt, Montreal
These forms of deep brain stimulation require a surgical procedure during which electrodes — which generate electrical impulses to control any abnormal brain activity — are implanted into certain areas of the brain. With enough advancement in the field, doctors expect brain stimulation techniques for both severe disorders and health-and-wellness purposes will ultimately become noninvasive. Three major players There are only three companies with FDA-approved deep brain stimulation, or DBS, treatments: Medtronic , Abbott Laboratories and Boston Scientific . The spinal cord stimulation, or SCS, business is a hotbed of innovation right now, deep brain stimulation also is a key area." There is still plenty of doubt, however, about the efficacy of at-home brain stimulation devices, which offer a less direct approach to brain stimulation and don't always require FDA oversight.
Persons: , Bernstein, Lee Hambright, Hambright, Ali Rezai, Medtronic, Abbott, Rezai, Morningstar, Debbie Wang, Wang, Elon Musk, it's Elon Musk's, Casey Halpern, it's, Halpern, Taiwan's Organizations: Drug Administration, FDA, Abbott Laboratories, Boston, Rockefeller Neuroscience, West Virginia University, American Neuromodulation Society, Boston Scientific, DBS, FactSet, Neuroscience, BCI, University of Pennsylvania, TMS Locations: neuromodulation
CNN —Inflammation from belly fat may be linked to the early stages of Alzheimer’s disease decades before symptoms begin, new research has found. “That’s important because brain atrophy is another biomarker of Alzheimer’s disease,” Raji said. “These are people who, if they do develop Alzheimer’s disease, it won’t happen for another 20 or 25 more years. “Regardless of weight, people should find out if they have hidden visceral fat,” Raji said. Visceral fat ‘easier to lose’There’s good news: Visceral fat responds well to diet and exercise, Raji said.
Persons: , , Richard Isaacson, Isaacson, Cyrus Raji, St . Louis, ” Raji, Dr, Mahsa, Raji, ” Isaacson, It’s Organizations: CNN, Washington University School of Medicine, Radiology Society, Cleveland Clinic, Mayo Clinic Locations: Florida, St .
Listening to favorite songs could reduce people’s perception of pain, according to a new study published Wednesday in the journal Frontiers in Pain Research. And the most effective pain relievers were found to be sad songs detailing bittersweet and emotional experiences. He was not involved in the latest study but has conducted his own research on the relationship between pain and music. With millions of songs available, one person’s favorite song is likely not the same as another. While he didn’t research chills in this study, Valevicius hypothesized that these sensations might be signs of sensory gating.
Persons: CNN —, Adele, , Patrick Stroman, “ Cotton, , Darius Valevicius, shivers, Valevicius, Stroman, ” Jocelyn Solis, Moreira Organizations: CNN, Pain, Queen’s University, Sega, neurosciences, University of Montreal Locations: Kingston , Ontario, New York
This AI company wants to help you control your dreams
  + stars: | 2023-10-04 | by ( Hayden Field | ) www.cnbc.com   time to read: +2 min
It's a tech startup building what the company calls the "world's first wearable device for stabilizing lucid dreams." Lucid dreams occur when a person sleeping becomes aware they're dreaming and may be able to control parts of the dream. Humane AI, a company founded in 2017 by former Apple employees, debuted its wearable — the AI Pin — on the runway last week at Paris Fashion Week. And famed iPhone designer Jony Ive and OpenAI's Sam Altman are also reportedly discussing an AI hardware project. The co-founders have the type of lofty dreams typical of a modern-era tech startup, with Wollberg comparing the company to OpenAI.
Persons: Eric Wollberg, Wesley Berry, Wollberg, Berry, Grimes, BoxGroup, Card79, Jony, Sam Altman, Prometheus Organizations: a16z's Scout Fund, Plaid, Elon, Apple, Paris Fashion, Donders Institute for Brain, Radboud University Locations: Netherlands
The South Korean researchers last week said they found a superconductor that works at room temperature, which has long been considered a holy grail for scientists in the field. The South Korean researchers published two papers - one initial paper with three authors and a second, more detailed paper with six authors that included only two of the authors from the first paper. The gold standard for proof of discovery is other labs reliably replicating the South Korean researchers' findings. But another team, from Qufu Normal University, said they did not observe zero resistance, one of required characteristics of a superconductor. On Thursday, South Korean experts said they would set up a committee to verify the claims.
Persons: Read, Kelvin, Eric Toone, Bill Gates, Mike Norman, Norman, Sinéad Griffin, Lawrence, Griffin, apatite, Michael Fuhrer, Fuhrer, Argonne's Norman, Stephen Nellis, Joyce Lee, Brenda Goh, Krystal Hu, Kenneth Li, Deepa Babington Organizations: CEA, Nuclear Research, South, Reuters, South Korean, Huazhong University of Science, Technology, Qufu Normal University, Southeast University, Bill Gates ’, Energy Ventures, National Laboratory, Lawrence Berkeley National Laboratory, . Department of Energy, Monash University, Thomson Locations: ., China, South Korea, Nanjing, Melbourne, Australia, San Francisco, Seoul, Shanghai, New York
CNN —The US Food and Drug Administration is expected to decide on Thursday whether to grant traditional approval to the Alzheimer’s drug Leqembi, the first medicine proven to slow the course of the memory-robbing disease. Leqembi, from drugmakers Eisai and Biogen, received accelerated approval in January based on evidence that it clears amyloid plaque buildups in the brain that are associated with Alzheimer’s disease. But because of an earlier coverage decision by CMS, which provides insurance coverage for many elderly patients with Alzheimer’s through Medicare, the drug hasn’t been widely used. People with more advanced forms of the disease may not benefit from the drug, he said, and may face increased safety risks. Broad Medicare coverage of Leqembi and similar types of medications to slow the progression of Alzheimer’s disease would probably have a big impact on the program’s spending.
Persons: drugmakers, hasn’t, , ’ ”, Joe Montminy, Lawrence Honig, “ It’s, , Honig, it’s, Leqembi, ” Honig, Georges Naasan, Sue Rottura, ” Drugmaker Eisai, “ You’re, Ivan Cheung, Eisai, ” Montminy, Dr, Sanjay Gupta Organizations: CNN, Food and Drug Administration, Medicare, Services, CMS, Columbia University Irving Medical Center, Alzheimer’s, Behavioral, CNN Health, Kaiser Family Foundation Locations: Mount, Florida
Some long Covid patients swear by the treatment, with one describing it to CNBC Make It as a "total game changer." That's a huge stumbling block for many medical experts, who caution against viewing it as a universal remedy for long Covid. Most of the ones who do get treated have reported improved long Covid symptoms, the clinic adds. That's because a variety of underlying physiological conditions — like chronic lung issues, for example — can "drive different manifestations of long Covid," says Dr. Lucy Horton, an infectious disease physician who founded the long Covid clinic at UC San Diego Health. "For many [Covid] long haulers, including myself, financial freedom is gone because we can't work full-time."
Eli Lilly (LLY) has spent decades researching Alzheimer's disease without successfully bringing to market a treatment that slows the memory-destroying condition. For Eli Lilly as a company, an Alzheimer's drug is an important pursuit. Lilly's Alzheimer's history Eli Lilly's "first real foray" into Alzheimer's came in the 1990s, according to Dr. John Sims, Eli Lilly's head of medical development for donanemab. Financial implications for Lilly LLY mountain 2021-10-08 The Club started a new position in Eli Lilly (LLY) in October 2021. The Eli Lilly logo is shown on one of the company's offices in San Diego, California, September 17, 2020.
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