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Dow Jones - 2 Katsuhiko Hayashi - 1 Matt Krisiloff - 1
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☆ What If Men Could Make Their Own Egg Cells?
  + stars: | 2023-10-27 | by ( Amy Dockser Marcus | ) www.wsj.com   time to read: 1 min
The Japanese biologist Katsuhiko Hayashi said earlier this year that he believes it will be possible to create a human egg from skin cells within a decade. He and his colleagues have already turned skin cells from male mice into mouse eggs and used them to breed baby mice. Matt Krisiloff , chief executive officer of Conception Biosciences, has dozens of scientists working at a lab in Berkeley, Calif., trying to make eggs outside ovaries. Such a technique could allow women to have biological children later in life.
Persons: Katsuhiko Hayashi, Matt Krisiloff Organizations: Conception Biosciences Locations: Berkeley, Calif
☆ Doctors Transplanted a Pig Kidney Into a Person a Month Ago. It’s Still Working.
  + stars: | 2023-08-16 | by ( Amy Dockser Marcus | ) www.wsj.com   time to read: 1 min
This copy is for your personal, non-commercial use only. Distribution and use of this material are governed by our Subscriber Agreement and by copyright law. For non-personal use or to order multiple copies, please contact Dow Jones Reprints at 1-800-843-0008 or visit www.djreprints.com. https://www.wsj.com/articles/pig-kidney-transplant-medicine-research-7e75dbab
Persons: Dow Jones
☆ Two Children Learn the Truth About Their Donor Father and Build a New Family
  + stars: | 2023-06-16 | by ( Amy Dockser Marcus | Photographs David Walter Banks For The Wall Street Journal | ) www.wsj.com   time to read: 1 min
This copy is for your personal, non-commercial use only. Distribution and use of this material are governed by our Subscriber Agreement and by copyright law. For non-personal use or to order multiple copies, please contact Dow Jones Reprints at 1-800-843-0008 or visit www.djreprints.com. https://www.wsj.com/articles/anonymous-sperm-donation-dna-tests-new-family-7127fca0
Persons: Dow Jones
☆ The Future of Health
  + stars: | 2023-04-20 | by ( ) www.wsj.com   time to read: 1 min
These Drugs Are So Futuristic That Doctors Need New TrainingNext-generation treatments on the way for once-incurable diseases can be complicated to test and administer; "if we can’t get it to these patients, the science is lost." By Amy Dockser MarcusLyndon French for WSJ
☆ These Drugs Are So Futuristic That Doctors Need New Training
  + stars: | 2023-04-05 | by ( Amy Dockser Marcus | Photographs Lyndon French For The Wall Street Journal | ) www.wsj.com   time to read: 1 min
A major obstacle looms for the drugs of the future. Not enough doctors know how to administer them. For just one rare neurodevelopmental disorder, known as Angelman syndrome, clinical trials are testing four cutting-edge therapies. Twenty more research programs are under way and could yield treatments ready to move into human testing in the next several years, according to Allyson Berent-Weisse, chief scientific officer of the Foundation for Angelman Syndrome Therapeutics, or FAST, and the mother of a child with the disorder.
☆ WHO Presses China to Release Raccoon Dog Data in Search for Covid’s Origins
  + stars: | 2023-03-17 | by ( Drew Hinshaw | Betsy Mckay | Amy Dockser Marcus | ) www.wsj.com   time to read: 1 min
The closed Huanan Seafood Market in Wuhan, the site of the first known Covid case cluster, in January 2020. Chinese authorities are withholding genetic evidence that could provide clues about the origins of the Covid-19 pandemic, the World Health Organization said, pointing to data temporarily posted online by Chinese scientists, and then removed, that indicated the presence of wild animals at a Wuhan market. China’s Center for Disease Control and Prevention in late January briefly published genetic sequences done in 2020 that appear to show the presence of raccoon dogs and other animals at China’s Huanan Seafood Market in Wuhan, site of the first known Covid case cluster, WHO officials said Friday.
☆ FDA Widens Path for Rare-Disease Treatments With New Approval
  + stars: | 2023-02-28 | by ( Amy Dockser Marcus | ) www.wsj.com   time to read: 1 min
Photo: Eric Lee for The Wall Street JournalThe Food and Drug Administration, headquartered in Silver Spring, Md., has said it is willing to approve a drug based on results from one trial and “confirmatory evidence.”Federal regulators approved a drug to treat a debilitating disease using data collected about patients over decades, creating an opening for researchers of other rare conditions who often struggle to prove their treatments work. The Food and Drug Administration on Tuesday approved Reata Pharmaceuticals Inc.’s drug Skyclarys, or omaveloxolone, for treating the neurological disorder Friedreich’s ataxia in adults and adolescents age 16 and older.
☆ Making Medical Science More Democratic
  + stars: | 2023-02-10 | by ( Amy Dockser Marcus | ) www.wsj.com   time to read: +1 min
Members of the nascent British Association for the Advancement of Science gathered in Cambridge in 1833 to discuss the state of the field. Science was an increasingly popular pursuit and was helping to expand knowledge about the natural world. One of the association’s founders, William Whewell , was ready with an answer: scientists. In the century that followed, science was transformed from a vocation to a profession. Universities became the central venue for the pursuit of science.
☆ 71-Year-Old Cancer Patient Broke Trial Age Limits for a Chance at a Cure
  + stars: | 2023-01-09 | by ( Amy Dockser Marcus | Photographs Ian Bates For The Wall Street Journal | ) www.wsj.com   time to read: 1 min
After Mikhail Rubin learned his lethal blood disease had progressed, he decided that he wanted a stem-cell transplant through a clinical trial. But there was an obstacle: his age. Mr. Rubin, who is now 72, was too old to participate. Many cancer trials cap enrollment at age 65. People over 70 represent a growing share of the cancer-patient population but are vastly underrepresented in clinical trials, the study said.
☆ Stanford President’s Research Draws Concern From Scientific Journals
  + stars: | 2022-12-16 | by ( Amy Dockser Marcus | ) www.wsj.com   time to read: 1 min
Stanford University President Marc Tessier-Lavigne is said to be working with scientific journals and the Stanford board of trustees to resolve questions about the accuracy of images in his research. Two major scientific journals expressed concern over years-old studies co-written by Stanford University president and neuroscientist Marc Tessier-Lavigne , stopping short of corrections or retractions. Science and Cell wrote in so-called editorial expressions of concern on Thursday that they would await the outcome of an investigation by Stanford and the papers’ authors before determining whether additional steps were necessary.
☆ Doctors and Lawyers Debate Meaning of Death as Families Challenge Practices
  + stars: | 2022-12-11 | by ( Amy Dockser Marcus | ) www.wsj.com   time to read: 1 min
Recent scientific advances raise the prospect of further blurring the line between life and death. How doctors determine death is up for debate. For more than four decades, death in the U.S. has been determined in two main ways. Life ends when the heart and lungs stop working. Or physicians might declare a person brain-dead, defined as the irreversible cessation of all brain function, even if the heart and lungs can be maintained with machines.
☆ FDA Plans to Allow More Gay, Bisexual Men to Donate Blood
  + stars: | 2022-11-30 | by ( Liz Essley Whyte | Amy Dockser Marcus | ) www.wsj.com   time to read: 1 min
People donating at a blood drive hosted by the New York Blood Center in the East Village in New York. Gay and bisexual men in monogamous relationships would be allowed to donate blood without abstaining from sex under guidelines being drafted by the Food and Drug Administration, people familiar with the plans said. The change would be a departure from U.S. policy that for many years barred men who have sex with men from donating blood at all. The FDA policy originated in the 1980s during the AIDS epidemic when tests for HIV, the virus that causes AIDS, weren’t considered sensitive enough to protect the blood supply.
☆ FDA to Allow More Gay, Bisexual Men to Donate Blood
  + stars: | 2022-11-30 | by ( Liz Essley Whyte | Amy Dockser Marcus | ) www.wsj.com   time to read: 1 min
People donating at a blood drive hosted by the New York Blood Center in the East Village in New York. Gay and bisexual men in monogamous relationships would be allowed to donate blood without abstaining from sex under guidelines being drafted by the Food and Drug Administration, people familiar with the plans said. The change would be a departure from U.S. policy that for many years barred men who have sex with men from donating blood at all. The FDA policy originated in the 1980s during the AIDS epidemic when tests for HIV, the virus that causes AIDS, weren’t considered sensitive enough to protect the blood supply.
☆ Pig’s Heart Took Longer to Generate a Beat in Transplant Patient
  + stars: | 2022-10-31 | by ( Amy Dockser Marcus | ) www.wsj.com   time to read: 1 min
The transplant took place in January, and the recipient died in March. A genetically modified pig heart transplanted into a severely ill person took longer to generate a heartbeat than those of typical pig or human hearts, research showed, another potential challenge for doctors aiming to conduct clinical trials of pig-organ transplants. Doctors took daily electrocardiograms of David Bennett , a 57-year-old handyman and father of two who received a gene-edited pig heart in an experimental surgery at the University of Maryland Medical Center in Baltimore in January. Mr. Bennett died in March from heart failure, but doctors still aren’t sure why the pig heart thickened and lost its pumping ability.
☆ Parents of Donor-Conceived Children Face New Calls for Candor
  + stars: | 2022-09-24 | by ( Amy Dockser Marcus | ) www.wsj.com   time to read: 1 min
Parents of children conceived from donated sperm, eggs or embryos can be reluctant to tell their kids about their genetic origins out of concern that doing so would compromise the parents’ privacy or upend family harmony. These mothers and fathers are facing pressure to change. Research now shows that donor-conceived people fare better emotionally when they learn about their origins early on. And states are starting to enact laws that require people intending to make use of donor gametes or embryos be informed about the importance of telling donor-conceived children about their origins.
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