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That amounts to more than 10% of annual premature deaths in Brazil among that age group. The authors say their study is the first to estimate the impact of ultra-processed food on the risk of early death. The authors applied that model to Brazil's population and level of ultra-processed food consumption. Ultra-processed foods can often be identified by their long list of ingredients, many of which you wouldn’t normally find in your own kitchen. Willett also said that there may be little benefit to replacing ultra-processed foods with certain items, such as more red meat or foods cooked in a lot of butter.
An earlier study in adults showed that the drug did indeed help with weight loss. “We’ve entered the phase where we are seeing the kind of weight loss where teens come to us in tears. In addition to the weight loss, the drug reduced some cardiovascular risk factors, including waist circumference and bad cholesterol. As it turns out, even when people get weight loss surgery, “three years out, there is significant weight gain,” Li said. When a weight loss drug like this is prescribed to patients, that shouldn’t be the end of things, Li said.
On Thursday, the billionaire investor Vinod Khosla spoke about reducing costs in healthcare. Vinod Khosla thinks the best way to disrupt healthcare is to change how it's paid for at the primary-care level. The billionaire investor and founder of Khosla Ventures said he thought that in the next decade, primary care should cost as little as $1 to $5 per visit. "If you change the definition of primary care from what is today's primary care, or urgent care mostly, to a much-broader definition where your hypertension is managed in primary care, where your diabetes is managed in primary care, you will see that take over and affect the core total cost of care downstream," he said. For instance, a company like Oak Street Health can operate primary care at a loss because it makes money if its patients stay healthy.
This little-known California-based biopharmaceutical stock can see its shares rally nearly 80% in the near term, according to Goldman Sachs. Shares of the company's stock were up more than 5% in trading Thursday on the back of Choi's call. The analyst also sees promise in the company's pipeline of Bruton's tyrosine kinase inhibitor drugs, currently in the works to treat a slew of conditions including some forms of lymphoma and potentially multiple sclerosis. The bank's price target suggests shares can soar another 78% from Wednesday's close. "We are broadly bullish on GOSS's pipeline and view the risk/reward profile at current levels as favorable," he said.
Here are Thursday's biggest calls on Wall Street: Morgan Stanley reiterates Amazon as a top pick Morgan Stanley said shipping and fulfillment remain "key profit drivers" heading into the e-commerce giant's earnings next week. Headwinds from the interest rate spike on financing costs and valuation are tough to ignore despite strong demand growth from IRA and rising utility rates. UBS reiterates McDonald's as buy UBS said the fast food chain is "defensive." UBS reiterates Nike as buy UBS said its recent survey checks give the firm "increased" conviction in the stock. Morgan Stanley reiterates Tesla as overweight Morgan Stanley said Tesla's earnings report on Wednesday was strong but that the outlook for 2023 is still "at risk."
On an adjusted operational basis, which excludes the impact of acquisitions and divestitures and currency, sales rose 8.2%. Management said on the call they continue to see this business on track for its 11th consecutive year of above-market adjusted operational sales growth in 2022. Driving the results were increased sales of Stelara on the back of market growth and market share gains in Crohn's Disease and Ulcerative Colitis. Women's Health sales increased 7.9% on an operational basis to $225 million versus the $222 million expected. On a reported basis, management tightened their EPS guidance range to $10.02 to $10.07 from $10 to $10.10 previously.
Merck's blood vessel disorder drug succeeds in late-stage study
  + stars: | 2022-10-10 | by ( ) www.reuters.com   time to read: +1 min
Oct 10 (Reuters) - Merck & Co (MRK.N) said on Monday a therapy it gained through the drugmaker's $11.5 billion acquisition of Acceleron Pharma last year met the main goal of a late-stage study in patients with a progressive blood vessel disorder. Sotatercept, when compared to placebo, significantly extended how far patients with pulmonary arterial hypertension (PAH) could walk in six minutes. The trial data validates the Acceleron acquisition, and also supports Merck's budding portfolio of cardiovascular drugs, Truist Securities analyst Robyn Karnauskas said in a note. Pulmonary arterial hypertension is a rare type of high blood pressure that affects an estimated 40,000 people in the United States, according to Merck. Register now for FREE unlimited access to Reuters.com RegisterReporting by Khushi Mandowara and Mrinalika Roy in Bengaluru; Editing by Shailesh KuberOur Standards: The Thomson Reuters Trust Principles.
Undergoing in vitro fertilization using frozen embryos is linked to a greater risk of hypertensive disorders, including preeclampsia, during pregnancy, according to research published Monday in the journal Hypertension. Overall, the risk of hypertensive disorders was low: about 7.4% in women who used frozen embryos, compared with 5.6% in women who used fresh embryos and 4.3% for women who conceived naturally. In addition, they found, there was no significant difference in risk between the women who conceived naturally and those who did IVF using fresh embryos. The group included 4.4 million naturally conceived pregnancies and compared them to just over 78,000 IVF pregnancies conceived using a fresh embryo and about 18,000 using a frozen embryo. Petersen emphasized that the overall risk for preeclampsia was still low and that the results of the new study should not scare women away from using frozen embryos.
Fall in love with a job you don't even like, in 3 steps
  + stars: | 2021-09-06 | by ( David G. Allan | ) edition.cnn.com   time to read: +10 min
There are also factors connected to job happiness that we have little control over, such as your boss. But we don’t usually decide who our boss is, and they can suddenly change (for good or bad). And — in my own, less scientific, more DIY way — here are exercises I’ve been practicing to get into better work happiness shape. And the third lists things you’d like to be able to do in your job that you currently don’t — even if they have nothing to do with what you’re paid to do. Beyond whatever the job itself accomplishes, there is also meaning and purpose with what you do with your wages.
Persons: CNN —, Henry David Thoreau, , Amy Wrzesniewski, Jane E . Dutton, It’s, I’ve, you’re, Michael, Jamie, Collin, Fiona, Saeed, ” Wrzesniewski, , ’ ”, “ That’s, Onboarding, You’re Organizations: CNN, Conference Board, Yale University, University of Michigan, Stanford Graduate School of Business, Harvard Business School
That doesn’t mean you’re doomed to wake up in a daze because you’re prone to mouth breathing when you sleep. “Even if you don’t have sleep apnea, or you have mild sleep apnea, opening your mouth makes it much, much worse.”How do you know if you’re mouth breathing at night? How to stop mouth breathingWhen Nestor blocked his nose for science, he experienced an extreme version of mouth breathing. If you’re tackling your nighttime mouth breathing, Park suggested you start by taking care of your nose to minimize congestion. But even if you get your nose to clear, nighttime mouth breathing can be a hard habit to break.
Factorii de risc în apariţia hipertensiunii„Hipertensiunea arterială secundară este o formă rară de hipertensiune şi reprezintă aproximativ 5-10% . Alimentele sărate cresc tensiunea. „Aportul de sare: retenţia de sodiu determină hipervolemie prin reabsorbţia secundară de apă, cu creşterea debitului sistemic şi, consecutiv, creşterea tensiunii arteriale sistolice. De asemenea, cantitatea crescută de sodiu se depune în peretele vascular cu creşterea rezistenţei vasculare şi, implicit, hipertensiune arterială diastolică“, explică dr. Corina Georgiana Tămăşescu. În concluzie, pentru menţinerea sub control a tensiunii arteriale, sunt necesare modificări ale stilului de viaţă asociate cu un tratament hipertensiv.
Persons: Corina Georgiana, Corina Georgiana Tămăşescu Locations: Bucureşti, postresuscitare
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