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Stelara, introduced in 2009, has been J&J’s top-selling drug since 2019, with sales reaching $9.7 billion in 2022. J&J is forecasting $57 billion in pharmaceutical sales by 2025 after reducing its previous view of $60 billion in April, citing currency dynamics that hurt its pharmaceutical business in 2022. That would add around $4.6 billion to average estimates for pharmaceutical sales, as long as no biosimilars enter the market before 2025. Amgen said last month the confidential settlement it signed with J&J will allow it to sell its Stelara biosimilar no later than Jan. 1, 2025. “If no Stelara biosimilars enter in 2024, I think growth should continue at around 4% in 2023 and 2024,” Huynh said.
Persons: Johnson, Amgen, , Vamil, Trung Huynh, ” Huynh, Teva, biosimilar, Divan, Alvotech, Patrick Wingrove, Caroline Humer, Bill Berkrot Organizations: Amgen Inc, Analysts, Stelara, Reuters Graphics Reuters, Reuters, New, J, Credit Suisse, Food and Drug Administration, Alvotech’s, Thomson Locations: New Brunswick , New Jersey, Alvotech’s Reykjavik
Kipyegon shaved almost an entire second off the previous mark of 3:50.07 set by Ethiopia's Genzebe Dibaba in 2015. The world record completes the 29-year-old's collection of feats, adding to her two Olympic 1,500m golds and the 2017 and 2022 world titles, Commonwealth Games gold medal from 2014 and three Diamond League titles. Dina Asher-Smith, who won the world 200 metres title in Doha in 2019, pulled out in the build-up to the race. Spaniard Mohamed Katir produced a lung-busting performance to win the 5,000m with a world leading 12:52.09, with world record holder Joshua Cheptegei coming in fourth. Reporting by Aadi Nair in Nashik, India; Editing by Ken FerrisOur Standards: The Thomson Reuters Trust Principles.
Persons: Pietro Mennea Golden, Luigi Ridolfi, Kipyegon, Remo Casilli FLORENCE, Fred Kerley, Ethiopia's Genzebe, Britain's Laura Muir, Jessica Hull, Muir, Ferdinand Omanyala, Trayvon, Jamaica's Yohan Blake, Jacobs, Ivorian Marie, Josee Ta Lou, Gina Lueckenkemper, Imani, Lara Lansiquot, Dina Asher, Smith, Ta Lou, Erriyon Knighton, Grant Holloway, Mohamed Katir, Joshua Cheptegei, Italy's Leonardo Fabbri, Andy Diaz, Larissa Iapichino, Aadi Nair, Ken Ferris Organizations: Diamond League, Commonwealth Games, Kenyan, Rabat, Thomson Locations: Florence, Italy, Ivorian, Doha, Netherlands, Rabat, Nashik, India
[1/2] Visitors stand next to a "Make In India" logo during a three-day semiconductor event in Bengaluru, India, April 30, 2022. They were from the Vedanta-Foxconn JV; a global consortium ISMC which counts Tower Semiconductor (TSEM.TA) as a tech partner; and from Singapore-based IGSS Ventures. SETBACK FOR VEDANTAMost of the world's chip output is limited to a few countries like Taiwan, and India is a late entrant. Amid much fanfare, in September, the Vedanta-Foxconn JV announced its chipmaking plans in Gujarat. Modi called the $19.5 billion plan "an important step" in boosting India's chipmaking ambitions.
Persons: Munsif, India's Modi, Taiwan's Foxconn, Narendra Modi, IGSS, Rajeev Chandrasekhar, Modi, Foxconn, STMicro, Chandrasekhar, David Reed, Aditya Kalra, Jane Lanhee Lee, Steven Scheer, Nick Zieminski Organizations: Visitors, REUTERS, Companies, Intel, India's Vedanta, Vedanta, IGSS Ventures, JV, Reuters, Orbit, Foxconn JV, Twitter, Thomson Locations: India, Bengaluru, DELHI, OAKLAND , California, Singapore, Gujarat, Taiwan, New Delhi, Oakland , California
Musk revealed those plans on Tuesday at the company's annual meeting, an about-face for the celebrity executive who recently acquired social media platform Twitter. Musk told CNBC he did not yet have a "fully formed strategy" for Tesla advertising. Tesla spent $151,947 on advertising in the U.S. in 2022, according to advertising intelligence firm Vivvix, which measured ads across places including TV, social media, Web banners and billboards. Diaz-Ortiz is a former Twitter manager who has written books about the social media company. Thomas Martin, senior portfolio manager at Tesla shareholder Globalt Investments, sees Musk's embrace of advertising as a positive.
JERUSALEM, May 17 (Reuters) - Bezeq Israel Telecom (BEZQ.TA) reported flat quarterly profit on Wednesday, and said it expects to reap benefits from an exponential expansion of data created by artificial intelligence (AI) platforms through more lucrative fibre optics growth. Bezeq is working with Nokia to provide broadband speeds of up to 25 gigabits per second (Gbps) and said it plans to offer 10 Gbps in 2024, reaching 25 Gbps by 2027. It currently offers a maximum of 2.5 Gbps. Fischbein also said that he remained comfortable with Bezeq's forecast of 1.2 billion shekels of net profit in 2023. Shares of Bezeq were up 0.3% to 5 shekels in afternoon Tel Aviv trading, but are nearly 18% lower so far in 2023.
In 2017, with Mr. Connors’ help, Mr. Maichle started his own company, Precision Compliance Consulting. ‘Boss Man’Mr. Connors, Mr. Lewis and Mr. Maichle were all active in college conservative politics in Wisconsin about 15 years ago, when Mr. Connors was the leader of campus Republicans at Marquette University. Of that, about $102,000 went to Campaign Now, the firm started by Mr. Connors, and another $112,000 to companies where Mr. Connors, Mr. Maichle or Mr. Lewis was either the owner or a partner, tax records show. Most of the money — more than $4.4 million — went to fund-raising companies via tens of thousands of small payments. Most of the money — more than $4.4 million — went to fund-raising companies via tens of thousands of small payments.
The suspects on Wednesday were traveling to a rocket launch site in the city of Khan Younis, the IDF said. A CNN producer in Gaza reported explosions in Khan Younis, Rafah and northern Gaza. Shortly after, he saw at least six rockets fired from Gaza towards Israel. Smoke billows following renewed Israeli military strikes launched into Gaza on May 10, 2023. Mahmud Hams/AFP/Getty ImagesMedics transport a victim to Shifa Hospital following the deadly Israeli airstrikes launched into Gaza on Tuesday.
CNN —The Equal Rights Amendment (ERA), which states that equal rights under the law cannot be denied on account of sex, has been in a perpetual state of limbo for 100 years. And worldwide, those dreaming of gender equality will have to wait another 300 years, according to the latest United Nations estimates. Arguably, billionaires will land on Mars before we achieve gender equality. With odds like those, it’s well worth asking: What does “achieve gender equality” even mean? It’s past time to give up the ghost of equality and pursue a goal that has hope of transforming women’s lives for the better: freedom.
Tori Bowie, World Champion Sprinter, Is Dead at 32
  + stars: | 2023-05-03 | by ( Daniel E. Slotnik | ) www.nytimes.com   time to read: +1 min
Bowie’s world championship title came the next year in London in a dramatic 100-meter race. Ivory Coast’s Marie-Josée Ta Lou sprung into the lead and seemed well ahead of the rest of the pack. But near the end of the race, Bowie accelerated, caught up to Ta Lou and leaned through the finish line ahead of her, then tumbled to the ground. Bowie won another gold at that world championship, in the 4x100 relay. Bowie went to the University of Southern Mississippi, where she became the national champion in the long jump in 2011.
Former world 100m champion Bowie dies aged 32
  + stars: | 2023-05-03 | by ( ) www.reuters.com   time to read: +1 min
[1/4] Athletics - World Athletics Championships – women’s 100 metres victory ceremony – London Stadium, London, Britain – August 7, 2017 – Tori Bowie of the U.S. (Gold) poses with her medal. REUTERS/Matthew ChildsMay 3 (Reuters) - Former 100 metres world champion Tori Bowie has died at the age of 32, her management company said on Wednesday. The American was crowned world champion in 2017 and won three Olympic medals at the Rio Games in 2016. "We're devastated to share the very sad news that Tori Bowie has passed away," Icon Management said in a statement on Twitter. Olympic medallist Calvin Davis has died at the age of 51, the sport's governing body World Athletics said in a statement on Wednesday.
During a conference call with investors, the company projected that adjusted gross margins will climb above 40% in the second half, having hit historic lows in the first half of the year. Underscoring Intel's profitability slump in recent years, its first-quarter unadjusted gross margin fell to 34.2%, almost half of its multi-decade high of over 67% in 2010. The company forecast a further drop to an unadjusted gross margin of 33.2% for the second quarter. "While we understand investors may be disappointed in its 2Q23 gross margin outlook, we are confident that Intel's gross margin will recover in 2H23 as the burden of factory underutilization and new product start-up cost diminishes," said Kinngai Chan, analyst at Summit Insights Group. Intel said adjusted losses were 4 cents per share, above analysts' expectations of a 15 cent per share adjusted loss.
A leaked internal document detailed Shopify's plan to overhaul its recruiting strategy. It said that recruiters needed to raise the bar for the quality of candidates they were bringing on to the company. "To do this, we will exhaustively seek out world class talent, scorching the earth with thoroughness and precision," it continued. The leaked internal document from Shopify cited a January conversation with CEO Tobi Lütke where he emphasized the need to hire fewer people managers and more people who had deep technical knowledge. It also said that Lütke instructed org leaders to "avoid high drama negative talent."
TA-TA, soulless stainless ranges. Cheerio, monolithic marble islands. A few years back, a new status kitchen—imported primarily via a pair of posh British outfits called Plain English and deVOL—surfaced stateside. Modeled loosely on the below-stairs service kitchens once found on grand estates, it quickly found a cult following for its homely hallmarks: pared-back Georgian cabinetry in moody colors, from chalky green to dishrag pink; studiously aged taps and cupboard latches; commodious “larders” in which to corral microwaves and other conspicuously 21st-century appliances; open shelving where vintage copper pots rub shoulders with ancestral oil paintings. Think of it as the “old-money look” for kitchens.
Takeaways from Biden's trip to Ireland
  + stars: | 2023-04-14 | by ( Kevin Liptak | ) edition.cnn.com   time to read: +10 min
Biden’s trip came as he nears a decision on running again for president. “I own property in Ireland, I’m not going to Ireland,” former President Donald Trump said during Biden’s trip. Patrick Semansky/APDiplomatic legacy: ‘Keep the peace’White House officials made little attempt at ascribing major policy objectives to Biden’s trip. Kevin Lamarque/ReutersBiden makes Ireland visit a family affairMore than anything, Biden’s trip this week had the feeling of a family spring break. Throughout the sometimes-rainy trip, Biden kept his head dry with a baseball cap from the Beau Biden Foundation.
Lidar technology is used for 3D mapping, navigation and object detection in various high-tech industries. Ouster's complaints said Hesai incorporated its digital lidar technology into the Shanghai-based company's sensors. Ouster accused Hesai's sensors of infringing five patents covering core aspects of its digital lidar technology. It asked the Delaware court for an unspecified amount of money damages and the ITC to bar imports of infringing Hesai products. Hesai settled a patent dispute with San Jose, California-based Velodyne Lidar Inc in 2020.
Romania aims to buy F-35 fighter planes to boost air defences
  + stars: | 2023-04-11 | by ( ) www.reuters.com   time to read: +1 min
BUCHAREST, April 11 (Reuters) - Romania aims to buy the latest generation U.S. F-35 fighter planes to boost its air defences, the country's supreme defence council (CSAT) said in a statement on Tuesday. The European Union and NATO state has raised defence spending to 2.5% of gross domestic product this year from 2%, in response to Russia's invasion of Ukraine. Last year, President Klaus Iohannis said Romania was mulling acquiring F-35 planes, which are made by U.S. weapons maker Lockheed Martin Corp (LMT.N). In March, the defense ministry said Romania would buy Abrams tanks made by General Dynamics (GD.N), as part of wider defence acquisitions plans. In December, Romania's defence ministry signed a deal to acquire seven Watchkeeper X unmanned aircraft systems from Israeli defence electronics firm Elbit Systems (ESLT.TA) for roughly 1.89 billion lei ($418.02 million).
The local utility in charge of overseeing the interconnection process told Pine Gate it would be more than $30 million. Pine Gate had to terminate the project because it couldn't afford the new fees, its vice president of regulatory affairs, Brett White, told CNBC. "Those projects ended up withdrawing from the queue or terminating, because they don't pencil anymore," White told CNBC. "There is Texas, and then there's the rest of the country with respects to interconnection," White of Pine Gate told CNBC. And that means getting those engineers out of some of the rote manual data entry and into the actual analysis," White told CNBC.
In an industry of around 400,000 there are currently around 6,000 vacant tech jobs, according to government data. More than half of the country's startups held an account with SVB, companies and venture capital investors said, in some cases their only U.S. banking facility although the amounts involved are not fully known. Tech companies and investors alike said SVB was a rarity in the banking industry, familiar with Israel's tech ecosystem and offering loan terms unmatched by other banks. Citing the judicial reforms, Adam Fisher, a partner at investment firm Bessemer Venture Partners, said fewer American banks may be willing to lend to Israeli companies, which means less competition and more onerous terms. Israel's tech companies are therefore likely to flock to register as U.S. companies, while keeping R&D back home, said Yaron Samid, managing partner of the TechAviv Founder Partners fund.
Such "skinny labels" typically allow generic drugmakers to launch their products earlier while avoiding liability for infringing brand-name drugmakers' patents. GSK sued Teva for patent infringement in Delaware federal court in 2014 over its generic version of Coreg. In its petition to the Supreme Court last year, Teva said the ruling would cause "havoc" for skinny labels, which it said are "extraordinarily common" and "save patients and the federal government billions." GSK countered that the case does not threaten generic drugmakers that "operate properly under the law." The Biden Administration backed Teva on Wednesday, arguing generic drugmakers should be entitled to rely on the FDA's carve-out instructions, which are based on brand-name drugmakers' own statements to the agency.
William Drew, director of content for Asia's 50 Best Restaurants, said Japan's strong performance is "no surprise." The top 50 restaurants in AsiaThis year commemorates the 10th anniversary of the "Asia's 50 Best Restaurants" list. Asia's top 50 restaurantsThe list of "Asia's 50 Best Restaurants" for 2023 are: 1. Ten restaurants that ranked among Asia's best 50 restaurants last year fell into the 51-100 ranking this year. Asia's 50 Best Restaurants 2023Labyrinth also rose 29 spots to No.11, winning the "Highest Climber" award.
US FDA approves first OTC opioid overdose reversal drug
  + stars: | 2023-03-29 | by ( ) www.reuters.com   time to read: +2 min
[1/2] A box of NARCAN nasal spray is photographed at an outpatient treatment center in Indiana, Pennsylvania, U.S. on August 9, 2017. The approval for OTC use of the naloxone-based nasal spray will help align the federal government's stance with states that have provisions to offer the drug without prescription at pharmacies. Drug-related overdose deaths in the United States rose about 15% year-over-year to more than 100,000 in 2021, as per official data. While the approval puts Emergent ahead in the OTC product race, analysts have said it is not likely to derive significant sales from the approval. Benchmark analyst Robert Wasserman said ahead of the approval that Narcan sales peaked in 2020 and have declined since.
LONDON, March 28 (Reuters) - BP (BP.L) and Abu Dhabi's state oil giant on Tuesday offered to acquire 50% of Israeli offshore natural gas producer NewMed Energy (NWMDp.TA) for around $2 billion, making their entry into Israel's growing energy sector. The offer would involve acquiring NewMed's free floating shares and taking the company private. BP shares gained 2% by 0810 GMT while NewMed shares were up around 30%. For BP, the deal highlights the British company's focus on growing natural gas production after Chief Executive Bernard Looney last month slowed down its shift away from fossil fuels. After the deal closes NewMed will become a private corporation equally held by the BP-ADNOC JV and Delek Group (DLEKG.TA), which holds the remaining 50%.
Morning Bid: Swinging between bank fears and rate risks
  + stars: | 2023-03-28 | by ( ) www.reuters.com   time to read: +5 min
A look at the day ahead in U.S. and global markets from Mike DolanMarkets seem caught between the devil and the deep blue sea. Easing concerns about bank stability this week have merely re-introduced interest rate risk, reining in any suggestion of a runaway relief rally as the first quarter closes on Friday. While nerves persist over March bank failures and contagion fears, central banks are still faced with punchy growth and inflation and will likely switch attention back to cooling that down once they're assured banks can take the strain. But interest rate markets are already correcting as signs of stability in the banking arena emerge. They do not reflect the views of Reuters News, which, under the Trust Principles, is committed to integrity, independence, and freedom from bias.
Lenders, energy stocks help London stocks extend gains
  + stars: | 2023-03-28 | by ( ) www.reuters.com   time to read: +1 min
SummarySummary Companies FTSE 100 up 0.6%, FTSE 250 adds 0.2%March 28 (Reuters) - UK shares extended gains on Tuesday, supported by an upbeat performance in energy heavyweight BP, while lenders gained following reassuring comments by Bank of England Governor Andrew Bailey on the stability of the banking sector. The pound strengthened 0.3% as traders weighed the prospects of higher interest rates. The blue-chip FTSE 100 (.FTSE) rose 0.6%, while FTSE 250 (.FTMC) climbed 0.2% by 0718 GMT. Energy stocks (.FTNMX601010) rose 1.6%. Reporting by Johann M Cherian in Bengaluru; Editing by Sherry Jacob-PhillipsOur Standards: The Thomson Reuters Trust Principles.
BP, ADNOC’s Mediterranean debut ticks three boxes
  + stars: | 2023-03-28 | by ( ) www.reuters.com   time to read: +2 min
LONDON, March 28 (Reuters Breakingviews) - BP (BP.L) and the Abu Dhabi National Oil Company (ADNOC) are tying the knot. The duo plan to set up a joint venture to buy gas assets in the eastern Mediterranean. On the other hand, the $4 billion NewMed net asset value implied by BP and ADNOC’s bid is some way ahead of the $2.6 billion estimated by hedge fund Palliser during NewMed’s autumn dalliance with Capricorn Energy (CNE.L). And after rethinking the speed with which it’s cutting its oil and gas production, BP wants to show investors that it can identify suitable fossil fuel projects. NewMed shares only jumped 38% to around 10 shekels on Tuesday, implying doubt about whether the deal will happen.
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