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☆ Biotech investor Brad Loncar shares 10 predictions for 2023, including a hot new cancer target, Nobel Prize winners, and a biotech founder running for president
▼ + stars: | 2023-01-04 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +14 min

Loncar shared his 2023 forecast, including new drugs, Nobel Prize winners, and more globalization. Brad Loncar isn't expecting a miraculous rebound for the biotech industry in 2023. In an interview with Insider, Loncar shared 10 predictions for biotech in 2023, ranging from Nobel Prize winners and presidential runs to hot cancer targets and bankruptcy worries. 2022 was a rough year for the biotech industry, which once again underperformed the stock market. The industry runs to the next super-hot cancer target: Claudin 18.2In cancer research, drug companies are always on the hunt for the next promising target.

☆ Citi names its top biotech stock picks for 2023 — and gives one 73% upside
▼ + stars: | 2022-12-30 | by ( Weizhen Tan | ) www.cnbc.com time to read: +2 min

Biotech has been a "stock-pickers market" — and it may have just what it takes to remain one in 2023, according to Citi. Under a bad recession scenario, Citi prefers names with large cash balances and which have already commercialized drugs, or which are on the verge of drug approvals. Some names that meet those criteria include Apellis Pharmaceuticals , Acadia Pharmaceuticals and Amylyx Pharmaceuticals , Citi said. Its pre-clinical pipeline could also "drive long-term value across a number of large market opportunities." "[Its] strong cash position makes BEAM attractive even in a hard-landing scenario," Citi said.

☆ How Cerebral went from a hyped $4.8 billion mental-health startup to fighting for its survival
▼ + stars: | 2022-12-22 | by ( Blake Dodge | ) www.businessinsider.com time to read: +10 min

It called itself the fastest-growing mental-health company. Some Cerebral clinicians told Insider they were uncomfortable treating the patients assigned to them and felt their licenses were at risk. In the past few years, highly funded startups have tried to disrupt mental-health care and struggled. Cerebral's next steps will dictate its future, and its story could influence what's ahead for online mental-health care. A former Cerebral provider told Insider the ban was frustrating because many patients who were improving on the drugs lost access to care at Cerebral.

☆ A Parasite May Explain Why Some People Are Driven to Start a Company
▼ + stars: | 2022-12-21 | by ( Adam Rogers | ) www.businessinsider.com time to read: +14 min

When wolves in Yellowstone National Park get infected with a cat parasite called Toxoplasma gondii, they become more likely to leave their packs and start new ones. The Yellowstone wolf data hints that it's just the side effect of a protozoan inhabiting our brains in a failed attempt to make more protozoa. So why would any of this make an infected wolf want to start its own pack? That was the suggestion of an influential 2006 paper titled "Can the Common Brain Parasite, Toxoplasma gondii, Influence Human Culture?" Just because Toxo might drive an alpha male to start a company, that doesn't mean it'll be a successful company.

☆ Suicide prevention: Signs, risk factors and how to help
▼ + stars: | 2022-12-14 | by ( Kristen Rogers | ) edition.cnn.com time to read: +11 min

CNN —Suicide is a leading cause of death among children and adults, but spotting risk factors and warning signs isn’t easy. Here are some of the most common behavioral, verbal and emotional signs and risk factors you should pay attention to, according to experts. Mood and other risk factorsPsychological factors, distressing situations or genetics can increase the likelihood of someone considering, attempting or dying by suicide, according to SAMHSA. These risk factors can’t cause or predict a suicide attempt, but being aware of them is important, according to SAMHSA:Hopelessness. “You’re not going to cause someone to be suicidal by asking directly about suicide,” Baker said.

☆ Elon Musk showed off updates to his brain chips and said he’s going to install one in himself when they are ready
▼ + stars: | 2022-12-01 | by ( Ashley Capoot | ) www.cnbc.com time to read: +3 min

Elon Musk's health tech venture Neuralink shared updates to its brain-implant technology during a "show and tell" recruitment event Wednesday night. "We're confident there are no physical limitations to restoring full body functionality," Musk said. Neuralink could begin to test the motor cortex technology in humans in as soon as six months, Musk said. "You could have a Neuralink device implanted right now and you wouldn't even know. Musk showed footage of a monkey with a computer chip in its skull playing "telepathic video games," which Neuralink first debuted over a year ago.

☆ 'Mind-control' parasites make wolves likelier to be pack leader
▼ + stars: | 2022-11-30 | by ( Kate Golembiewski | ) edition.cnn.com time to read: +6 min

CNN —Wolves are pack animals, living in family groups led by a matriarch and her mate. Researchers found that gray wolves in Yellowstone National Park infected with a parasite known as Toxoplasma gondii were more likely to leave the group of wolves they were born into or become a pack leader. Kira Cassidy/NPSRisky behavior of infected animalsScientists have been monitoring wolves in Yellowstone National Park since the species was reintroduced there in 1995. Pack behavior is observed via trail cameras and plane flyovers, and about a quarter of the wolves wear radio tracking collars and undergo blood tests. “The more we learn about wolf behavior, the better we can understand how to conserve the species,” she said.

In the early 2010s, Mr. Mellow set out for still more distant shores, traveling to many famous surf breaks in the South Pacific. Mr. Abdul-Rashed and Mr. Danian traveled to Hawaii to connect with Mr. Mellow, their spiritual guide and Pacific expedition leader. Mr. Mellow posted an ad on Facebook and Craigslist offering $10,000 for passage to the South Pacific. Mr. Schmidt was in sync with the young seekers when it came to fear of Big Brother and vaccines, but dreading port officials brandishing nasal swabs struck even Mr. Schmidt as a little unhinged. When asked if he was at all responsible for what had happened to Mr. Danian and Mr. Abdul-Rashed, Mr. Mellow looked genuinely confused.

☆ Billionaires like Elon Musk want to save civilization by having tons of genetically superior kids. Inside the movement to take 'control of human evolution.'
▼ + stars: | 2022-11-17 | by ( Julia Black | ) www.businessinsider.com time to read: +40 min

"We are the Underground Railroad of 'Gattaca' babies and people who want to do genetic stuff with their kids," Malcolm told me. Ellison, meanwhile, who has two children in their 30s, has reportedly resumed having kids — with his 31-year-old girlfriend. "The person of this subculture really sees the pathway to immortality as being through having children," Simone said. The person of this subculture really sees the pathway to immortality as being through having children. Before she met Malcolm, Simone was convinced she wanted to live her life single and child-free.

Aaron Carter's older brother Nick, and twin sister, Angel, posted their first public statements following Carter's tragic death in tributes posted to Instagram Sunday. Angel Carter and Aaron Carter at their 19th birthday party in Hollywood, Calif., on Dec. 15, 2006. Despite what he called a "complicated" relationship with his younger brother, Nick Carter said he has always loved him. Conrad starred in the 2006 "House of Carter" reality show with Carter and their other siblings, including "Backstreet Boys" singer Nick Carter. Carter's death at the age of 34 sparked a number of tributes from those in the entertainment industry.

☆ Singer Aaron Carter, 34, found dead in his home, reports say
▼ + stars: | 2022-11-05 | by ( ) www.reuters.com time to read: +1 min

Nov 5 (Reuters) - Aaron Carter, who won early fame as a child pop star and toured with his brother's hit band Backstreet Boys before pursuing careers in rap and acting, was found dead in his home near Los Angeles on Saturday, according to media reports. There were no reports that foul play was suspected in Carter's death. Carter, 34, released his debut album in 1997 when he was just 9 years old, becoming a child pop star who frequently appeared on Nickelodeon, according to TMZ and The Hollywood Reporter. He turned to rap later in his music career, and also acted in productions such as the Broadway Show "Seussical." Carter went to drug rehabilitation centers on multiple occasions, most recently earlier this year, in an effort to regain custody of his son, Prince, according to The Hollywood Reporter.

CNN —Aaron Carter, a former child pop singer and younger brother of Backstreet Boys’ Nick Carter, has died, a source close to the family told CNN. Carter, who first found fame as a boy with pop songs like “I Want Candy” and “Crush on You,” is survived by his 11-month-old son, Prince. The singer’s debut studio album, “Aaron Carter,” was released in 1997 and he performed as the opening act for the Backstreet Boys earlier that year. “There’s something I’d like to say that I feel is important for myself and my identity that has been weighing on my chest for nearly half of my life,” Carter wrote on Twitter. The singer later said in an interview that he doesn’t drink and denied that he has a drug problem, CNN previously reported.

☆ Family of Detroit man killed by police during mental health crisis sues city, 5 officers for $50 million
▼ + stars: | 2022-11-02 | by ( Minyvonne Burke | Minyvonne Burke Is A Senior Breaking News Reporter For Nbc News. | ) www.nbcnews.com time to read: +4 min

The mother of a young Detroit man shot more than a dozen times by police during a mental health crisis filed a $50 million lawsuit against the city and five unidentified officers. Burks' brother informed officers that the 20-year-old was in the midst of a mental health crisis and only had a pocketknife on him, the lawsuit said. "The Department will continue to advocate for greater resources for the mental health community and will take every opportunity to improve its response to people suffering from mental illness," he said. "We firmly believe that if appropriate mental health facilities and treatment plans had been available, this situation may have been avoided. Regrettably, the DPD remains the primary emergency response service for individuals suffering from mental health emergencies."

☆ Oklahoma to execute man for 2002 killing of infant daughter
▼ + stars: | 2022-10-20 | by ( The Associated Press | ) www.nbcnews.com time to read: +3 min

McALESTER, Okla. — A 57-year-old Oklahoma man is scheduled to receive a lethal injection on Thursday for killing his 9-month-old daughter in 2002, despite claims by his attorneys that he is mentally ill and not competent to be executed. Oklahoma State Department of Corrections / AFP - Getty ImagesThe panel voted 4-1 to deny clemency, and a district judge earlier this month determined Cole was competent to be executed. Assistant Attorney General Tessa Henry said Cole killed his daughter because he was infuriated that her crying from her crib interrupted his playing of a video game. “He is not severely mentally ill,” said another prosecutor, Assistant Attorney General Ashley Willis. “The evaluator, who was not hired by Cole or the State, found Cole to be competent to be executed and that ‘Mr.

☆ There are signs of change in the M&A market. Bank of America gives their buyout candidates
▼ + stars: | 2022-10-17 | by ( Alex Harring | ) www.cnbc.com time to read: +3 min

Health and tech are providing heat in what is otherwise a lukewarm year for merger and acquisition deals, according to Bank of America. The bank reported 150 deals so far this year, which annualized comes in about 9% lower than last year. That makes sense given lower market returns typically make for a weaker deal landscape, said strategist Jill Carey Hall. Bank of America screened for small-cap companies that could have merger or acquisition potential. It also boosted its revenue outlook for the third quarter to between $112 million and $115 million from between $96 million and $100 million.

☆ Biden’s Choose-Your-Own Covid Pandemic Policy
▼ + stars: | 2022-10-14 | by ( The Editorial Board | ) www.wsj.com time to read: 1 min

President Biden’s answer is yes no yes no. The latest example of politically convenient pandemic schizophrenia came Thursday when the Department of Health and Human Services again extended the official public-health emergency, this time through January. “The pandemic is over,” Mr. Biden told CBS’s “60 Minutes” only three weeks ago. But the pandemic is over.” Not to get all philosophical, but how can something be an emergency if it has already ended? The HHS statement this week says “a public health emergency exists and has existed since January 27, 2020, nationwide.”

☆ Scientists Grow Human Cells in Rat Brains to Study Autism, Schizophrenia
▼ + stars: | 2022-10-12 | by ( Daniela Hernandez | ) www.wsj.com time to read: 1 min

Bioengineered human tissue transplanted into rat brains generated hybrid neural circuits that affected the animals’ behavior, researchers said, expanding a pathway for exploring brain development and the mechanics of some diseases. Neuroscientists at Stanford University transplanted tiny blobs of neural tissue known as organoids into the brains of newborn rats. The human cells grew and made functional connections within the rat brain, generating hybrid neural circuits, the researchers said in a study published Wednesday in the journal Nature.

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