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And some people opt to get their caffeine through energy drinks or caffeine pills. In rarer scenarios, an overconsumption of caffeine can lead to a state called caffeine intoxication or caffeine overdose. Caffeine intoxication occurs when a person has dangerously high levels of caffeine in the system. While rare, there is always a potential for caffeine intoxication if a person is drinking irresponsibly. Caffeine intoxication is more than the headache you get from drinking too much expresso.
Persons: Erin Palinski, Wade, Oleg Breslavtsev, Nima Majlesi, Majlesi, , you’ve, you’re, Jocelyn Solis, Moreira Organizations: CNN, National Coffee Association, US Food and Drug Administration, EKP Nutrition Communications, Staten Island University Hospital, Palinski Locations: New Jersey, New York
One of the few treatments the Food and Drug Administration has approved for amyotrophic lateral sclerosis has failed a large clinical trial, and its manufacturer said Friday that it was considering whether to withdraw it from the market. The medication, called Relyvrio, was approved less than two years ago, despite questions about its effectiveness in treating the severe neurological disorder. At the time, the F.D.A.’s reviewers had concluded there was not yet sufficient evidence that the medication could help patients live longer or slow the rate at which they lose functions like muscle control, speaking or breathing without assistance. But the agency decided to greenlight the medication instead of waiting two years for results of a large clinical trial, citing data showing the treatment to be safe and the desperation of patients with a disease that often causes death within two to five years. Now, results of the 48-week trial of 664 patients are in, and they showed that the treatment did not work better than a placebo.
Persons: Organizations: and Drug Administration Locations: United States
Which diseases can pets transmit to their owners?
  + stars: | 2024-02-29 | by ( Katia Hetter | ) edition.cnn.com   time to read: +7 min
CNN: What types of diseases can household pets like cats and dogs transmit to humans? Dr. Leana Wen: Just as humans can transmit diseases to other humans, animals can transmit diseases to others in their own species. Sometimes, animals can transmit diseases to other species, and that includes humans with whom pets have had close contact. These diseases spread when a person is bitten by an infected tick that has fed off an infected animal. It’s not known how the man who died from Alaskapox contracted it, but a possible route is an infected animal biting the individual or exposure of an infected animal to an existing break in the man’s skin.
Persons: Leana Wen, Wen, Lyme, Alaskapox, It’s Organizations: CNN — Health, CNN, George Washington University Locations: Alaska, Oregon, United States
Sam Bankman-Fried, co-founder of FTX Cryptocurrency Derivatives Exchange, arrives at court in New York, US, on Thursday, Feb. 16, 2023. "The harm to customers, lenders, and investors is zero," Bankman-Fried's lawyers wrote. The lawyers wrote that Bankman-Fried has a "neurodiversity" that "greatly affects how he perceives and is perceived." It is not a disease or a condition that needs to be cured," the lawyers wrote. "Individuals with ASD are often at considerably greater risk of physical harm and extortion in prison than other inmates," the lawyers wrote.
Persons: Sam Bankman, Fried, Joseph Bankman, Barbara Fried, Lewis Kaplan, , Michael Milken, Damian Williams, Williams, Kaplan, Marc Mukasey, Sam, Drexel Burnham Lambert, Milken Organizations: Bankman, Alameda Research, The Manhattan U.S, PSR, Defense, Drexel, CNBC PRO Locations: New York, FTX, Manhattan, Alameda, Brooklyn , New York
Bankman-Fried's lawyers filed a sentencing submission, asking for a prison sentence of no longer than 78 months — or six-and-a-half-years. The US Probation Office, which issues sentencing reports that judges typically rely on, recommended 100 years behind bars — which Bankman-Fried's lawyers called "barbaric." Advertisement"That recommendation is grotesque," Bankman-Fried's lawyers wrote. Sam Bankman-Fried's approach to veganism illustrated both his selflessness and awkwardness, his younger brother, Gabriel Bankman-Fried, wrote in a letter to the judge. In the sentencing submission, Bankman-Fried's lawyers argue that "the most reasonable estimate" for how much his victims lost was "zero."
Persons: , Sam Bankman, Barbara Fried, Joseph Bankman, Gabriel Bankman, neurodiversity, Sam, Bankman, Lewis Kaplan, Fried, Jane Rosenberg, FTX, Michael M Santiago, Carmine Simpson, Simpson, That's, Gabriel, Seth Wenig, Marc Mukasey, Torrey Young, weren't, Barbara Fried —, John J, Ray III, John Ray Organizations: Service, Business, US, Prosecutors, Alameda Research, Office, Stanford Law, MIT, Wall, of Prisons, San, United, AP Locations: Manhattan, FTX, Brooklyn, Bahamas
Long Covid may lead to measurable cognitive decline, especially in the ability to remember, reason and plan, a large new study suggests. Cognitive testing of nearly 113,000 people in England found that those with persistent post-Covid symptoms scored the equivalent of 6 I.Q. But the experts said the findings are important because they provide numerical evidence for the brain fog, focus and memory problems that afflict many people with long Covid. “These emerging and coalescing findings are generally highlighting that yes, there is cognitive impairment in long Covid survivors — it’s a real phenomenon,” said James C. Jackson, a neuropsychologist at Vanderbilt Medical Center, who was not involved in the study. He and other experts noted that the results were consistent with smaller studies that have found signals of cognitive impairment.
Persons: , , James C, Jackson Organizations: The New England, of Medicine . People, Vanderbilt Medical Center Locations: England, The
Washington CNN —President Joe Biden is fit for duty, his doctor reported Wednesday following the president’s annual physical, in what is expected to be the last update on Biden’s health before November’s election. Dr. Kevin O’Connor said in a memo there are “no new concerns” with the president’s health revealed by this year’s physical. The White House said earlier Wednesday that no cognitive test was administered as O’Connor did not find it necessary. The procedure was “successfully completed” at the White House by a team from Walter Reed, O’Connor said. Reports from the White House physician over the last several decades have consistently described the office-holder as fit to serve.
Persons: Joe Biden, Kevin O’Connor, ” O’Connor, Biden, , SSRS, Karine Jean, Pierre, “ doesn’t, Donald Trump, Jonathan Reiner, ” Reiner, that’s, O’Connor, , Biden’s, ” Biden, Lou Gehrig’s, Robert Hur, I’ve, , seething Biden, “ I’ve, NBC’s, Seth Meyers, ” Wednesday’s Walter Reed, Walter Reed, CNN’s Kevin Liptak, Mira Cheng Organizations: Washington CNN, O’Connor, , State, CNN, Quinnipiac University, White, US Preventive Services, Force, Medical Unit, American Medical Association, National Institutes of Health, White House Locations: Beverly Hills , California, United States
Read previewAxel Bouchon cofounded Matter Neuroscience in 2019 after leading the venture arms of pharma giants Moderna and Bayer. AdvertisementMatter has emerged from stealth with $26 million from ARCH Venture Partners, Polaris Partners, Exor Ventures, and Collaborative Fund, Business Insider has learned exclusively. That $26 million includes an initial seed round led by Polaris Partners and a Series A round led by ARCH Venture Partners. The startup views itself now as a consumer biotech startup, Bouchon said. Here's the 17-slide pitch deck Matter used to raise $26 million.
Persons: , Axel Bouchon, Bouchon Organizations: Service, pharma, Moderna, Bayer, Business, Venture Partners, Polaris Partners, Exor Ventures, Fund, Brain Imaging, Icahn School of Medicine Locations: Maastricht, Netherlands, Mount Sinai, Seoul, South Korea
Kenneth Mitchell, a Canadian actor known for his roles on the series “Star Trek: Discovery” and the film “Captain Marvel,” died on Saturday. He had lived with the neurological disorder amyotrophic lateral sclerosis, or A.L.S., which causes paralysis and death, for more than five years, according to a statement from Mr. Mitchell’s family posted to his social media. Mr. Mitchell played the Klingons Kol, Kol-Sha, and Tenavik, as well as Aurellio, on “Star Trek: Discovery,” and voiced several other characters in an episode of “Star Trek: Lower Decks.”In “Captain Marvel,” he played the father of the superhero, Carol Danvers. He was also known for portraying Eric Green on the series “Jericho,” Joshua Dodd in the series “Nancy Drew,” a hockey player in the film “Miracle,” and appeared in several other film and television series.
Persons: Kenneth Mitchell, Marvel, , Mitchell’s, Mitchell, Kol, Captain Marvel, Carol Danvers, Eric Green, ” Joshua Dodd, Nancy Drew Organizations: Locations: Canadian
"Look Again" authors Tali Sharot (left) and Cass R. Sunstein explore how seeing things with fresh eyes can improve happiness, relationships, work and community. The blessing comes as diminished sensitivity to negative stimuli; the curse is that insensitivity relieves the pressure to change things and maybe make life better. CNN: What do you recommend for people considering big life changes? Sunstein: The data we have suggests, if you’re seriously thinking of making a life change, you probably should. Research shows that when people on the fence about moving to a different city, taking a new job or some other big life change do take the plunge, they report being better off months later.
Persons: shivers, Simon, Shuster, Tali Sharot, Cass R, it’s, we’re, “ I’ve, Michael Lionstar, Ross Lincoln, I’m, they’re, you’re, you’ll, Jessica DuLong, Organizations: CNN, Harvard University, Shuster CNN, Variety Locations: Brooklyn , New York
There's been a lot of chatter about the mental health crisis since the Covid-19 pandemic. Attention to a long-time crisis The mental health crisis is nothing new. However, there has also been a growing awareness and acceptance of mental health illnesses over the past decade, said Canaccord Genuity analyst Richard Close. "There's been recognition that mental health has a significant impact on a person's overall health," he said. "This is the mental health moment," said Dr. Ken Duckworth, NAMI's chief medical officer and author of "You Are Not Alone: The NAMI Guide to Mental Health."
Persons: There's, Covid, Peter Micca, AbbVie, Emraclidine, Myers Squibb, Karuna, Marc Goodman, Canaccord, Richard Close, MacKenzie Scott, Ken Duckworth, NAMI, Deloitte's Micca, William Blair, Myles Minter, Minter, Auvelity, Leerink's Goodman, Ashwani Verma, Verma, Goodman, BioHaven, Cerevel, Neumora, tardive, David Song, BetterHelp, psychedelics Johnson, Johnson, Spravato, Blair's Minter, Axsome, Micca, Michael Bloom Organizations: Institute for Health Metrics, Deloitte, Cerevel Therapeutics, Karuna Therapeutics, Bristol Myers, Leerink Partners, Centers for Disease Control, National Alliance, Mental, Mental Health, Wall Street, Therapeutics, Neumora Therapeutics, UBS, Karuna, Cellular Therapies, Xenon Pharmaceuticals, Neurocrine Biosciences, Acadia Pharmaceuticals, Tema Neuroscience, Axsome Therapeutics, Acadia Healthcare, BetterHelp, CNBC, pharma, Cellular Locations: Covid, Bristol, XEN1101, Acadia, Tema
ATLANTA (AP) — Since Jimmy Carter entered hospice care at his home in south Georgia one year ago, the former U.S. president has celebrated his 99th birthday, enjoyed tributes to his legacy and lost his wife of 77 years. Those advocates commend the Carter family for demonstrating the realities of aging, dementia and death. Almost half of Medicare patients who died that year did so under hospice care. JIMMY CARTER’S ENDURANCE IS NOT UNUSUALIn 2021, the average stay of hospice patients who died was 92 days, MedPAC calculated. About 10% of enrollees who die in hospice care stayed more than 264 days.
Persons: Jimmy Carter, Rosalynn Carter, Carter, “ It’s, , Angela Novas, it’s, , Mollie Gurian, ” Gurian, Gurian, Chip Carter, Jimmy, Rosalynn, Novas, JIMMY CARTER’S, , Jimmy Carter’s, JIMMY CARTER, ” Novas Organizations: ATLANTA, Hospice Foundation of America, Medicare, Advisory, Novas, The Washington Post Locations: Georgia, Washington, Plains, U.S,
A photo of my birth mother holding me as a newborn, taken on July 4, 1995, in central Florida. On the one hand, getting tested would help me better plan my future, but I'd have to live with the reality if the diagnosis was positive. AdvertisementOn the other hand, not getting tested would always leave an ounce of uncertainty in the back of my head. It wasn't until 2018, when I met my now-husband, Ryan, that I gave getting tested another thought. Taylor Rains/Business InsiderAfter 10 years of uncertainty, a huge weight was lifted from my shoulders.
Persons: , Olivia Wilde's, Remy, Thirteen, Hadley, I've, Taylor Rains, Mary, Desiree, Taylor, goody, Ryan Organizations: Service, Florida Institute of Technology, Pearl Harbor Aviation Museum Locations: Florida, Puerto Rican, Spain, China, Alaska, Bulgaria, , Connecticut
Celine Dion was onstage at the 2024 Grammys to give out the album of the year award. She has not been seen much in public since she was diagnosed with Stiff Person Syndrome in 2022. It was a rare moment for Dion since she was diagnosed with a rare neurological condition. Stiff Person Syndrome is a disease that affects the brain and causes muscles to stiffen uncontrollably. But Dion did attend the Grammys this year, where she presented the most prestigious award, album of the year, to Taylor Swift.
Persons: Celine Dion, , Dion, Taylor Swift Organizations: Service
As my vision declined in my right eye, I began to struggle with lights at night, something I was convinced was a sign of a deadly disease — or my impending blindness. I began to consider laser eye surgery as a solutionFor the first time in my life, I began to seriously think about getting laser eye surgery. Despite coming across a few horror stories related to laser eye surgery of botched procedures and rare side effects, I decided to take the plunge. Being nearsighted is a risk factor for floaters, so I've had them for a long time, and unfortunately, laser eye surgery doesn't remove them. Laser eye surgery might not be for everyone.
Persons: Nearsightedness, I've, I'd, It's, there's, who've Organizations: Surgery
CNN —Living a healthy lifestyle with a focus on a nutritious diet, regular exercise, minimum alcohol consumption and other healthy habits can help keep your brain sharp into old age, doctors say. But what if your brain already has signs of beta amyloid or tau — two of the hallmark signs of Alzheimer’s and other brain pathologies? Will a healthy lifestyle still protect you from cognitive decline? Not everyone who has signs of Alzheimer’s or vascular dementia goes on to develop cognitive issues, but many do. In fact, “a higher healthy lifestyle score was associated with better cognition even after accounting for the combined burden of brain pathologies,” according to Yaffe and Leng.
Persons: , Dr, Klodian, Richard Isaacson, , Isaacson, wasn’t, , Kobus, Lewy, Yue Leng, Kristine Yaffe, Yaffe, San Francisco Weill Institute for Neurosciences . Leng, Leng, it’s Organizations: CNN, Rush Institute, Healthy Aging, Rush University, , University of California, San Francisco Weill Institute for Neurosciences . Locations: Chicago, Florida, San
Elon Musk said Neuralink successfully implanted its first brain chip in a human. Here's everything we know about the surgery that replaces a portion of your skull. download the app Email address Sign up By clicking “Sign Up”, you accept our Terms of Service and Privacy Policy . AdvertisementElon Musk said his brain-chip startup implanted its device in its first human patient on Monday. Here's what we know about the process, according to videos from the startup, as well as media reports.
Persons: Elon Musk, Neuralink, , Musk Organizations: Service, Elon, US Food and Drug Administration
Popham’s wife, Mel, would have a conversation with her husband and an hour later he would have “no recollection,” he tells CNN Sport. Richard Boardman, the lawyer representing the claimants, told CNN Sport that this is causing an “existential threat” to the game. “As far as the brain is concerned, it doesn’t matter what sport is played,” Michael Grey, a neuroscientist at the University of East Anglia, told CNN Sport. Nowinski, a WWE wrestler turned neuroscientist, told CNN Sport that head injury protocols need to go beyond treating concussion. The paper, which looked at 412 Scottish former international male rugby players aged 30 and above and 1,236 members of the public who had been matched for age, sex and socioeconomic status, found that the rugby players’ risk of a dementia diagnosis over time was just over twice as high.
Persons: Alix Popham, Mel, , Popham, ” Popham, I’ve, Alix Popham of Wales, Pat Riordan of, Stu Forster, Lenny Woodard, Woodard, , “ I’d, I’d, ” Woodard, Brook Joyner, Richard Boardman, ” Michael Grey, Chris Nowinski, Scott McIntyre, Nowinski, ” Ann McKee, ” Boardman, Roger Goodell, University of East Anglia Boardman, Grey, , ” Steve Borthwick of, Alun Wyn Jones, Paul Harding, ” Grey, McKee, it’s, aren’t, we’re, shouldn’t, weren’t, ” Alix Popham Organizations: CNN, CNN Sport, rugby, Rugby, Alix Popham of Wales offloads, Pat Riordan of Canada, Wales, Getty, World Rugby, Rugby Football Union, RFU, Welsh Rugby Union, WRU, Springer, University of East, National Football League Players, Wrestling Entertainment, WWE, Washington Post, Boston University CTE Center, British Medical, Exercise, NFL, NFL.com, University of East Anglia, RBS, Nations, University of Glasgow, Boston University, University of Sydney, Scottish, , “ Rugby, England Rugby, Boston University’s CTE, CTE Locations: France, Wales, England, Canada, Nantes, Europe, University of East Anglia, American, Woodward, Boston
Céline Dion presented Taylor Swift with the award for album of the year at the Grammys on Sunday. AdvertisementMusic's biggest night concluded with a surprise appearance from Céline Dion and a historic win for Taylor Swift. Did Taylor Swift disrespect or snub Celine Dion? Was she clearly distracted by someone behind her at the exact moment Celine Dion handed her the award? Céline Dion, Taylor Swift, and René-Charles Angélil at the 66th Grammy Awards.
Persons: Céline Dion, Taylor Swift, Swift, Dion, , Trevor Noah, Celine Dion, Kevin Mazur, The Recording Academy Dion, Claudette Dion, René, Charles Angélil, Christopher Polk, Jack Antonoff, Lana Del Rey, Laura Sisk, Swift's, doesn't, @Knesix, Taylor, CELINE DION, @blackboywrites, Celine, @veganmoviesnob, — Beverley Smith, — adam, @adamjmoussa, celine, — Kathleen Newman, @HuffleBoy, — Alex Goldschmidt, @alexandergold, The Recording Academy Swift Organizations: Sunday, Service, The Recording Academy, Billboard, Getty, Poet's Department Locations: Los Angeles, Japan, Tokyo
Celine Dion, the Canadian pop superstar who announced in 2022 that she has a rare neurological disease that makes it difficult for her to sing, appeared at the Grammy Awards to present the final award of the night, album of the year. Walking out to “The Power of Love,” Dion looked moved by the standing ovation, saying, “When I say that I’m happy to be here I really mean it from my heart.”“Those who have been blessed enough to be here,” she went on, “must never take for granted the tremendous love and joy that music brings to our lives and to people all around the world.”Dion, 55, first announced over a year ago that she has a condition called stiff person syndrome, which causes progressive stiffness in the body and severe muscle spasms, leading her to cancel a scheduled world tour. A five-time Grammy winner — including album of the year in 1997 — Dion has maintained a legion of fans around the world, and before the diagnosis, she was an active performer, delivering soaring hits such as “Because You Loved Me” and “My Heart Will Go On” alongside her newer music.
Persons: Celine Dion, ” Dion, , ” “, , — Dion Locations: Canadian
Elon Musk claimed on X that Neuralink's first human patient received their brain implant. AdvertisementElon Musk on Monday claimed in a post on X that a Neuralink brain implant has, for the first time, been inserted into a human patient's brain. "The first human received an implant from @Neuralink yesterday and is recovering well," Musk wrote. AdvertisementMusk previously said the Neuralink device would record and stimulate brain activity, acting as a "Fitbit in your skull," and claimed the implant would eventually "solve" conditions including autism and schizophrenia . "However, any for-profit medical device company also has a vested interest in generating a consumer base, which is why they make the sometimes grandiose claims they do."
Persons: Elon Musk, Musk, , Elon, Stephen Hawking, Hilary Brueck, Neuralink, Tesla, Lou Gehrig's, Insider's Brueck, Randy Bruno, Bruno, that's, Jason T, Eberl, Albert Gnaegi, Healthline Organizations: Service, Business, SpaceX, FDA, Reuters, Columbia University, Albert Gnaegi Center for Health, Saint Louis University
CNN —While Celine Dion’s performing career remains on hold as she lives with stiff person syndrome, a rare neurological disorder, she is chronicling her journey in a new documentary titled “I Am: Celine Dion” and remains optimistic that she’ll one day be able to take the stage again. “This last couple of years has been such a challenge for me, the journey from discovering my condition to learning how to live with and manage it, but not to let it define me,” she wrote on her Instagram page on Tuesday. “She’s doing everything to recover,” Dion’s older sister Claudette told Hello! Canada in September. “She’s a strong woman.”According to an official synopsis, “I Am: Celine Dion” will give viewers an intimate look inside her life “as she reveals her battle with Stiff Person Syndrome (SPS) and the lengths she has gone to continue performing for her beloved and loyal fans.”Capturing over a year’s worth of Dion’s life, including “never-before-seen” private moments, the doc will showcase the legendary singer navigating “her journey toward living an open and authentic life amidst illness.”“I Am: Celine Dion” will be directed by Oscar-winning director Irene Taylor and will stream on Prime Video, according to the news release.
Persons: Celine Dion’s, Celine Dion ”, , ” Dion, Priyanka Chopra, Dion, , Claudette, Oscar, Irene Taylor Organizations: CNN, , National Institute of Neurological Disorders Locations: Canada
Bristol Myers Squibb's Eliquis is a blood thinner used to prevent clotting, to reduce the risk of stroke. Bristol Myers Squibb's Opdivo is an immunotherapy used to treat cancers, including melanoma and lung cancer. Investors will get updates on Merck and Bristol Myers Squibb's plans for the years ahead when they report earnings on Thursday and Friday, respectively. That's unlike generics, which are cheaper copycats of small-molecule drugs like Bristol Myers Squibb's Eliquis. Bristol Myers Squibb is also testing a new form of Opdivo, which is currently administered into a patient's veins.
Persons: Johnson, William Blair, Matt Phipps, Bristol Myers, Johnson's, Merck's Keytruda, J's Stelara, Opdivo, Phipps, biosimilars, Eliquis, Biosimilars, Humira, JB Reed, Samsung's, Piper Sandler, Christopher Raymond, AbbVie, Raymond, Chris Schott, Schott, Robert Davis, Keytruda, Davis, JPMorgan's Schott, Bristol Myers Squibb, George Frey, J, Amgen, J confidentially, Mike Perrone, It's, Anna Moneymaker Organizations: New York Stock Exchange, Johnson, NYSE Big, Bristol Myers Squibb, Merck, Biden, William Blair & Company, CNBC, Guggenheim, Bristol, Leerink Partners, Bloomberg, Getty, Bioepis, JPMorgan, JPMorgan Health Care, Moderna, Bristol Myers, Karuna Therapeutics, Hardy, Huntsman Cancer Institute, University of Utah, Reuters, Teva Pharmaceuticals, Pharma, U.S . Department of Health, Human Services Locations: drugmakers, EY, Europe, U.S, Cambridge , Massachusetts, Arda, EY's Americas, Bristol, Salt Lake City , Utah, Washington , DC
Europe Faces a Measles Outbreak
  + stars: | 2024-01-24 | by ( Apoorva Mandavilli | ) www.nytimes.com   time to read: +1 min
Some cases of measles can be mild, but up to half of infected children may need medical attention, said Dr. David Sugerman, who leads the measles team at the Centers for Disease Control and Prevention. Children with measles may develop diarrhea and dehydration, pneumonia that leads to long-term respiratory difficulties, and brain inflammation that results in neurological problems, Dr. Sugerman said. Deaths from measles rose worldwide by 43 percent between 2021 and 2022, according to a report in November from the W.H.O. Measles is among the most contagious infections, and the virus can linger in the air for up to two hours. In the United States, the measles vaccine is given twice, at 12 to 15 months old, and at 4 to 6 years of age.
Persons: David Sugerman, Sugerman Organizations: Centers for Disease Control, Prevention Locations: United States
Christina Applegate was met with a standing ovation when she took to the Emmys stage as a presenter. Applegate was diagnosed with multiple sclerosis in 2021. But she says people don't need to clap every time she does something after her multiple sclerosis (MS) diagnosis. "In essence, because of her I'm going to have a better quality of life," Applegate told British Vogue. In February 2023, the actor told the Los Angeles Times that year's SAG Awards would likely be the last awards show she'd attend as an actor.
Persons: Christina Applegate, Applegate, , Edebiri, Anthony Anderson, Kelly Bundy, Abbott, Quinta Brunson, Selma Blair, Applegate hasn't Organizations: Service, New York Times, British Vogue, Los Angeles Times Locations: British
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