A NASA astronaut, a Russian cosmonaut, and a Japanese astronaut are about to spend the next two days aboard a tiny Soyuz capsule bound for the International Space Station.
The Soyuz, which ferries astronauts and cosmonauts to and from the International Space Station (ISS), has a vacuum-like toilet that sucks urine out of the space environment and into a collection bin.
Of course, since they're in space, the astronauts can strap themselves onto the station toilet so they don't float away while they're doing their business.
Thankfully, the culture of space travel has changed a lot, too, as more and more women become astronauts.
PBS did a fascinating interview with female astronauts and NASA engineers about what it was like when women first started going to space, and had to pee there: