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Increasingly, people are interested in pursuing how their genes may be affecting their health, nutrition, fitness potential and risk of injury. The global market for these direct-to-consumer genetic tests is projected to soar in the next several years, skyrocketing from $1.9 billion in 2023 to $8.8 billion by 2030, according to a market analysis report by Grand View Research. Still, some are intriguedDespite these issues, many remain intrigued by DNA fitness tests. Balance Gym recently partnered with FitnessGenes, a UK-based company that sells genetic tests, to help its clients achieve better results from their workouts. Time, and further scientific advances, may shed more light on whether DNA fitness tests are, or can be, useful.
Persons: they’re, there’s, Timothy Caulfield, “ I’ve, ” Caulfield, Caulfield, , Eva, Dylan MacKay, ” MacKay, , Devin Maier, Maier, ” Maier, MacKay, Melanie Radzicki McManus Organizations: CNN’s, CNN, Grand View Research, Indian, Australia’s National Rugby League, University of Alberta, University of Manitoba, FitnessGenes Locations: Europe, Orthopaedics, Uzbekistan, China, Edmonton, Winnipeg , Canada, Washington ,,
Walnut, a white-naped crane and internet celebrity, has passed away at age 42. That preference continued when she came to the institute; she showed no interest in breeding and even attacked male crane suitors. Photos You Should See View All 45 ImagesBut white-naped cranes are considered vulnerable by the International Union for Conservation of Nature. And as the offspring of two wild-caught cranes, Walnut’s genes were not represented in U.S. zoos. Once Crowe had gained her trust, he was able to artificially inseminate her using sperm from a male crane.
Persons: Chris Crowe, Walnut, ” Crowe, “ I’ll, Chris, Crowe Organizations: WASHINGTON, Conservation Biology Institute, National Zoo, International Crane Foundation, International Union for Conservation of Nature . Locations: Front Royal , Virginia, U.S, Mongolia, Siberia, Korea, Japan, China, Wisconsin
WASHINGTON (AP) — Women are far more likely than men to get autoimmune diseases, when an out-of-whack immune system attacks their own bodies — and new research may finally explain why. One theory is that the X chromosome might be a culprit. The X chromosome is packed with hundreds of genes, far more than males’ much smaller Y chromosome. Every female cell must switch off one of its X chromosome copies, to avoid getting a toxic double dose of all those genes. “We think that’s really important, for Xist RNA to leak out of the cell to where the immune system gets to see it.
Persons: , John Wherry, wasn’t, Howard Chang, Chang, ” Chang, Epstein, Barr, Chang’s, Xist, hadn't, Penn’s, they’re, Stanford’s Chang Organizations: WASHINGTON, Stanford University, University of Pennsylvania, Howard Hughes Medical Institute, Associated Press ’ Health, Science Department, Associated Press Health, Howard Hughes Medical Institute’s Science, Educational Media Group, AP
But if he were born today with access to gene therapy for spinal muscular atrophy, he might have been able to walk without assistance. He might have been able to live a life without fear of impending medical catastrophe. The way Mr. Parish sees it, the life he has lived will one day become something of a historical curiosity. His experience of S.M.A., with all the suffering it has entailed, will likely be rendered extinct. Gene therapy has seen remarkable and highly publicized success in recent months, from the Food and Drug Administration’s approval of what amounts to cures for sickle cell disease to the news that a boy with congenital deafness could hear for the first time in his life following gene therapy.
Persons: Tyler Parish, Parish Organizations: Food Locations: Boston
The need for more transplant organs is immense and growing. Researchers have transplanted genetically modified pig kidneys and hearts into people who were brain-dead to test whether they work in humans. Although Larry Faucette was too sick for a human heart transplant, University of Maryland doctors said he seemed physically strong enough for a genetically modified pig heart. It was more than a decade after the first heart transplant but long before such procedures became relatively routine. “We learned that the pig heart is an adequate substitute for a human heart.
Persons: Lawrence Faucette, Ann, he’d, ” Ann, Larry Faucette, Ann Faucette Ann, Larry, didn’t, , Robert Montgomery, , Shelby Lum, ” Montgomery, Xenotransplantation, Art Caplan, Caplan, Babe ”, ” Caplan, They’re, eGenesis, people’s, Dr, Mike Curtis, Sanjay Gupta, ” Curtis, hasn’t, Julie O’Hara, Jim Parsons, Jayme Locke, couldn’t, Locke, Parsons, NYU —, Montgomery —, O’Hara, ” Locke, David Bennett Sr, Mary, David Jr, Bartley Griffith, Bennett, they’ve, Muhammad M, Mohiuddin, Larry Faucette’s, David Bennett’s, ” Griffith, xenotransplantation Ann Faucette, Wilbur, White’s, Ann Faucette, NYU ethicist Caplan, they’re, NYU’s Montgomery, UAB’s Locke, Steve Wood, ’ Curtis, “ I’m, it’s, ” O’Hara, Bennett’s, Larry Faucette —, ” Bennett’s, Faucette, who’d, Griffith, would’ve, Kate, Lucy, Nadia Kounang Organizations: CNN, Food and Drug Administration, University of Maryland, FDA, National Institute of Allergy, NYU Langone Transplant Institute, NYU Langone's Transplant, NYU Grossman School, Medicine’s Department of Population Health, “ Disney, University of Alabama, Transplant Institute, Parsons Family, Birmingham, NYU, University of Maryland School of Medicine, Doctors, University of Maryland Medical Center, Uno, UAB, CNN Health, NFL Locations: Frederick , Maryland, United States, Montgomery, , Midwest, Yucatan, Maryland
Scientists based in Australia have found that mouse-sized male antechinus trade sleep to leave more time for reproductive activities during mating season, with one male who was monitored halving his sleep time during that period. Non-breeding dusky antechinus spend an average of 15.3 hours of the day asleep, according to the researchers. “Sleep restriction in breeding male antechinus is likely to be an adaptive behavioral response driven by strong sexual selection,” the paper said. To study the semelparous marsupials, researchers examined two antechinus species: dusky antechinus (Antechinus swainsonii) and wild agile antechinus (Antechinus agilis) both captive and wild. Lesku said researchers would next like to examine how male antechinus deal with restricting their sleep for three weeks.
Persons: ” Erika Zaid, , Erika Zaid, Francesca Leonard, Zaid, John Lesku, antechinus, ” Lesku, Erika Zaid “, Volker Sommer, ” Sommer, Lesku Organizations: CNN, La Trobe University, , University College London Locations: Australia, Melbourne
Gene therapy has allowed several children born with inherited deafness to hear. Globally, 34 million children have deafness or hearing loss, and genes are responsible for up to 60% of cases. Hereditary deafness is the latest condition scientists are targeting with gene therapy, which is already approved to treat illnesses such as sickle cell disease and severe hemophilia. Also, some people consider gene therapy for deafness ethically problematic. "This is real proof showing gene therapy is working,” Chen said.
Persons: , Zheng, Yi Chen, Dr, Yilai Shu, Chen, Eli Lilly, Akouos, he's, John Germiller, ” Germiller, , Lawrence Lustig, Teresa Blankmeyer Burke, ” Chen Organizations: Children's Hospital of Philadelphia, Fudan University, Shanghai Refreshgene Therapeutics, Regeneron Pharmaceuticals, Decibel Therapeutics, Columbia, Gallaudet University, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group, AP Locations: China, Shanghai, Philadelphia, Spain
People under 50 in the US are dying from colorectal cancer at an increasing rate. AdvertisementMore people under the age of 50 are dying of colorectal cancer than ever before, according to the American Cancer Association. The disease is sometimes called colon cancer or rectal cancer, depending on where it starts. When colorectal cancer is caught early, before it has spread, the chance a person will live for another five years is about 90%. AdvertisementShe now visits her gastroenterologist regularly, eats healthy, exercises, and raises awareness of the signs of colorectal cancer.
Persons: , Kimmie Ng, you've, JJ Singleton, Singleton, Lynch, Tom McKenna, Paula Chambers Raney, Doctors, gastroenterologist, Kim Schewitz, kschewitz@businessinsider.com Organizations: Service, American Cancer Association, Dana, Farber Cancer Institute, NBC Locations: Boston
Our genetics play a big role in how easy we find it to gain and lose weight. But it's possible to be a healthy weight despite your genes, an expert in the genetics of obesity said. Don't focus on calories aloneTo lose weight, you have to be in a calorie deficit , meaning you're burning more calories than you consume. Focus on your health over your appearancePeople want to lose weight for lots of reasons but a common motivation is to fit into societal beauty ideals. This can prove to be a weak motivator in the long run though, and doesn't necessarily benefit your health, Yeo said.
Persons: , it's, Giles Yeo, Yeo, you've Organizations: Service, University of Cambridge Institute of Metabolic, US News, Research
Intergenerational trauma is where the psychological effects of painful events are passed on in families. A psychotherapist shared five signs you might be experiencing intergenerational trauma. Symptoms of intergenerational trauma include difficulty regulating emotions and being overly suspicious. However, a person experiencing intergenerational trauma may not be consciously aware because the symptoms may have become normalized Hammond said. AdvertisementDifficult relationships in your family follow a patternOne of the most obvious indicators of intergenerational trauma is a repeating pattern of relationship dynamics in your family, Hammond said.
Persons: , Hendrix Hammond, Hammond, don't, I'd, you've, what's Organizations: Service Locations: London
Spirit Airlines , JetBlue Airways — The airline stocks slid after a federal judge blocked JetBlue Airways' proposed $3.8 billion acquisition of Spirit Airlines. JetBlue shares fell nearly 1%, while Spirit Airlines dropped more than 20%. SolarEdge Technologies — The solar stock fell 5% following a downgrade by Barclays to underweight from equal weight. Twist Bioscience — Shares climbed 3.2% on the heels of an upgrade to buy from neutral at Goldman Sachs. Ford — Shares shed 2.3% on the back of a UBS downgrade to neutral from buy.
Persons: Sinclair —, Sinclair, Goldman Sachs, Davidson, William Blair, Nutanix, Wolfe, Uber, Tesla, Morgan Stanley —, Ted Pick, Visteon, Morgan Stanley, Morgan, , Sarah Min, Yun Li, Jesse Pound, Michelle Fox Organizations: Spirit Airlines, JetBlue Airways —, JetBlue Airways, Bank of America Securities, Susquehanna Financial, JetBlue, LSEG, Diamond Sports Group, Diamond, Technologies, Barclays, Goldman, , Broadcom, VMware, Deutsche Bank, Ford —, UBS, JPMorgan, Polaris, Mattel Locations: Rivian, China
Read previewGenes that may have once helped ancient herders fight infectious parasites could contribute to autoimmune diseases today, like multiple sclerosis. For example, rates of MS are twice as high in the northwest of Europe, including in Scandinavia, compared to southern Europe. AdvertisementThey analyzed teeth and bones from Europe and Western Asia, adding to an ancient DNA database of about 1,600 genomes. Northern Europeans are also more susceptible to MS than in southern Europe, where Yamnayan ancestry is less common. AdvertisementFor some people, this inflammatory response can go overboard and start attacking the body's own cells, as with MS, Iversen said.
Persons: , it's, Rasmus Nielsen, Nielsen, Matthew Dunham NMB, immunologist Dr, Astrid Iversen, haven't, Iversen Organizations: Service, Business, University of Copenhagen, University of Cambridge, University of California, BBC Locations: Europe, Scandinavia, Western Asia, Berkeley, Northern
These genetic variants may have subsequently proved beneficial to European populations in making the shift from hunting and gathering to farming. “DNA from hunter-gatherers is present at higher levels in Northeastern Europe, which means the region has an elevated genetic risk of developing Alzheimer’s disease,” Barrie said. Similarly, the ancient genetic information shed light on the evolutionary history of traits such as height and lactose tolerance. And for most traits, MS included, the genetic effects are the result of multiple genetic variants,” he said. “Ultimately, we can’t say that MS came from Bronze Age populations, but these populations’ movements and environments contribute to differences in MS risk today.”
Persons: , , Rasmus Nielsen, It’s, William Barrie, Astrid Iversen, ” Iversen, ε4, ” Barrie, Samira, Asgari, Tony Capra, Capra, wasn’t Organizations: CNN —, University of California, Danish National, University of Cambridge’s, University of Oxford, Icahn School of Medicine, Bakar Computational Health Sciences Institute Locations: Western Europe, Central Asia, Europe, Berkeley, Kazakhstan, Northeastern Europe, Mount Sinai, New York, Bakar, San Francisco
CNN —With her signature megawatt smile and timeless style, Julia Roberts might be a beauty icon, but she doesn’t take herself too seriously. When asked in a new interview with British Vogue what keeps her looking youthful at 56, the actor responded with a wry wit. Lachlan Bailey/Vogue‘Leading a life that is fulfilling’Jokes aside, Roberts says the key to youthfulness is in the people and experiences that make up her life. Lachlan Bailey/Vogue‘They see something familiar’That audiences find her relatable is something Roberts is acutely aware of, for better or worse. Roberts also discussed how feminism shows up in her work, nodding to her decision not to do nude scenes in films.
Persons: Julia Roberts, “ Pickling, , ” Roberts, Hill, Richard Curtis, she’s, Lachlan Bailey, Roberts, , Erin Brockovich, that’s, Curtis, Anna Scott, I’m Organizations: CNN, Vogue, Globe, Locations: Hollywood, “ Notting, cardigan,
In the pharmaceutical industry, AI may one day accelerate new-drug development. In the foreseeable future, McClain expects the healthcare industry to use AI technology to design personalized medicines. Risks to considerWhile AI offers promise for the healthcare industry, there are also a variety of risks professionals using AI must consider and mitigate. Showalter said that a lack of "comprehensive regulations" can also make using AI technology in healthcare settings risky. With this in mind, he said, the medical industry must understand the "fundamentals of AI and its applications in healthcare."
Persons: , Sean McClain, McClain, Tim Showalter, Showalter, it's, Fred, haven't, Surya Josyula, Josyula Organizations: Experts, Service, Northwestern Medicine, Fred Hutchinson Cancer Center, UW Medicine, University of California, Fujitsu, Aichi Cancer, Fujitsu Laboratories of America Locations: University of California San Diego, Nagoya, Japan, China, United States
She's been greeted with hugs from strangers at the biannual convention for people with Williams syndrome, which make her "feel like a rockstar." That's common for those with Williams syndrome, said Mary Van Haneghan, the executive director of the WSA. Online environments can be difficult for people with Williams syndrome to navigate, says Joel Liestman, the director of family support at the WSA. She sees Williams syndrome as a gift and believes everyone could learn more empathy from those with the condition. He has had two relationships with women with Williams syndrome, but in both cases they didn't work out.
Persons: Tobi Akbas, he'd, Tobi, Williams, I've, Jackie Molloy, Terri, he's, Robert Boddie Jr, Boddie, Karen Levine, She's, There's, Haley Gallinger, Daren Bjerke, who's, Devin, John Martinez, Mary Van Haneghan, it's, doesn't, You've, neurotypical, Allie, Joel Liestman, That's, Callie Truelove, I'm, Jocelyn Krebs, Truelove, we're, he'll, we've, Levine, Josh Duffy, He's, Duffy, vlogs, We're, Hayley Cuccinello, Louise Ridley, Kevin Kaplan Organizations: Williams Syndrome Association, Business, Continental Village Fire Department, Tobi, Go, WSA, New York, Louise Ridley Design, Trenton Almgren Locations: Garrison , New York, Santa, Garrison, Peekskill , NY, recliners, Maine, Brunswick , Maine, labrador, New, New York City, Trenton
Orchid, a startup that tests embryos for genetic diseases, has just raised $12 million. "The way that IVF and embryo screening works today is the amount of information available is really limited," Orchid CEO and cofounder Noor Siddiqui said. Genetic testing has been around for years, but it has been usually limited in the diseases it can identify, which include cystic fibrosis, Bloomberg reported. Orchid produces reports with two types of genetic testing: monogenic and polygenic. The cost of the test depends on the number of embryos that Orchid tests.
Persons: Noor Siddiqui, Siddiqui, Orchid, Dylan, Anne Wojcicki, Fidji Simo, Peter Kraft Organizations: Business, Bloomberg, Prometheus Fund, Starbloom Capital, One Ventures, Los Angeles Times Locations: San Francisco, Pebblebed
Cancer specialists said the treatments have saved the lives of thousands of patients with blood cancers. And, he said, “I haven’t seen a single one” develop a new T cell cancer. When patients’ T cells are engineered to make proteins that attack cancer cells, a virus helps slip new genes into T cell DNA. Even without chemotherapy or radiation, Dr. Maus added, patients with blood cell cancers are especially susceptible to developing other blood cell cancers. But Dr. DiPersio said, “it is more of a smoking gun.”The F.D.A.
Persons: Marcela V, Maus, John DiPersio, Louis, , , DiPersio, , . Maus Organizations: Massachusetts General Hospital, Washington University School of Medicine Locations: Massachusetts, St
Some aspects of choosing a live Christmas tree, like shape, color, and aroma, are subjective. Two Christmas tree experts explain how to choose between the many types of fir, pine, and spruce. Unlike fir and spruce trees, pine tree needles are clustered in groups instead of individually attached to the branch. The National Christmas Tree Association has a map for finding farms and other retailers that sell live Christmas trees. AdvertisementWhich Christmas tree has the best aroma?
Persons: , there's, Fraser, Douglas, Noble, There's, Justin G, Whitehill, Bert Cregg, It's, Cregg, Chris Keane Whitehill, it's, Frasers, he's, Jason Reed Douglas, Mel Melcon, Jerry Holt, Bert, they'll, Alex Wong, Andrew Matthews, Tim Leedy, Paul J, Richards, Robert Nemeti, Jens Kalaene, you'll, Cesar L, Laure Organizations: Service, US Department of Agriculture, North Carolina State University, of Horticulture, Michigan State University, Northwest, REUTERS, White, Los Angeles Times, Getty, Star Tribune, MediaNews, Anadolu Agency, Call, Tribune Locations: Oregon, North Carolina, Michigan, Nobles , North Carolina, Douglas, Frasers, Fraser, Pacific Northwest, Europe, Canaan, Allentown
One portfolio manager, however, is shifting his focus to other tech players — particularly small mid-cap names. His comments come despite the sharp gains registered by big tech stocks which pushed the price-to-earnings ratio of the S & P 500 index to around 20 times. By contrast, the ratio is trading below 14 times when the seven Big Tech stocks are excluded, he noted. Another stock in Kharmandarian's AI and Robotics Fund fund is cybersecurity firm Crowdstrike . Electronic Design Automation Another theme on Kharmandarian's watchlist is electronic design automation — specifically companies designing the latest generations of semiconductors.
Persons: Karen Kharmandarian, Kharmandarian, bullish, Splunk Organizations: Big Tech, Apple, Microsoft, Nvidia, Tesla, Thematics Asset Management, CNBC, Robotics Fund, Cisco Systems, Cadence Design Systems, Pharmaceuticals, BioXcel Therapeutics
NEW YORK (AP) — It’s the season of giving thanks — and it turns out humans have been doing it for a long, long time. “This is something that is part of our human DNA,” said Sarah Schnitker, a psychologist at Baylor University. “It is a glue, in a sense, that holds us together.”How we got gratefulPolitical Cartoons View All 1260 ImagesHumans are social animals. Some scientists think the feeling of gratitude evolved to keep the helping exchanges going. Though we can’t “speak chimp” well enough to know if they’re actually saying thanks, Suchak added, it makes sense that some form of this social debt showed up early in our lineage.
Persons: , they've, , Sarah Schnitker, Michael Tomasello, Malini Suchak, capuchin, Suchak, Jenae Nelson, ” Nelson, they’re, Amrisha Vaish, Vaish, Schnitker, Nelson, “ It’s, Organizations: Baylor University, Duke University, Canisius University ., Baylor, Harvard, University of Virginia, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group, AP
Antimicrobial resistance (AMR), which the World Health Organization has referred to as the "silent pandemic," is an often overlooked and growing global health crisis. Sakis Mitrolidis | Afp | Getty ImagesMaking matters worse, research has shown that climate change is exacerbating the AMR crisis in several ways. "AMR bacteria is known as a silent pandemic. Extreme heat is fueled by the climate crisis, which makes extreme weather more frequent and more intense. "We hear people talking about this 'silent pandemic,' but it shouldn't be silent.
Persons: Sakis Mitrolidis, Tina Joshi, Joshi, University of Plymouth Robb Butler, Butler, Plymouth's Joshi Organizations: Planck, Biology, Getty, World Health, United, AMR, WHO, Afp, University of Plymouth, CNBC, UN, United Arab Emirates, Polygiene, Aircraft, Bloomberg, Plymouth's Locations: United Nations, Sikorahi, Alexandroupoli, Greece, WHO Europe, United Arab, UAE, Hamburg, Germany
NEW YORK (AP) — GOP front-runner Donald Trump marked President Joe Biden 's 81st birthday on Monday by releasing a letter from his physician that reports the former president is in “excellent” physical and mental health. Dr. Bruce A. Aronwald, a New Jersey physician who says he has been Trump’s doctor since 2021 and most recently examined him in September, reported that Trump's “physical exams were well within the normal range and his cognitive exams were exceptional." The report comes as age has emerged as a key issue of the 2024 election, which could find Trump and Biden, the country's oldest president, facing off once again. It takes the truth and moves it in a different direction.”While in the White House, Trump's doctors offered a more complete picture of his health following annual physicals that included numbers and test results. Trump continues to brag about the results to this day.
Persons: Donald Trump, Joe Biden, Bruce A, , Trump, Biden, , Ron DeSantis, , Harold N, ” Bornstein, Ronny Jackson, Trump’s, it’s, Jackson, Aronwald Organizations: GOP, Biden, Trump, Associated Press, NORC, for Public Affairs Research, , ” Florida Gov, CNN, Republican Locations: New Jersey, U.S, ” Florida
AdvertisementThe Sac Actun cave system on Mexico's Yucatán Peninsula contains many wonders, from a 13,000-year-old skeleton to human artifacts and fossils of giant sloths. The underwater cave microbial communityThe cave system is a network of over 900 miles of connected caves that contain a mix of freshwater and saltwater. Caves flooded with coastal seawater had different microbes than The Pit, a deep cenote exposed to the surface, for example. For example, she noted that a planned train system from Cancún to the Yucatán Peninsula could affect the cave system. The potential for contamination is a problem anywhere there are caves, Osburn said.
Persons: , It's, Magdalena, Osburn, Natalie Gibb, Comamonadaceae Organizations: Service, Northwestern University, Microbiology, Reuters Locations: Cancún, In Kentucky
What he saved he delivered to his only Jimmy Red customer two hours down the road in Charleston. “Not only was I counting on it, but High Wire Distilling was absolutely counting on it,” explained Coxe. A local moonshiner – and the last known grower of Jimmy Red corn – had just died, and the family no longer wanted to grow corn for whiskey distilling. Campbell Coxe harvests 50 acres of Jimmy Red corn on his Darlington, South Carolina, farm in September. This year, the distiller used 1.1 million pounds of Jimmy Red corn in its bourbon whiskey production.
Persons: Campbell, Coxe, , Red, moonshiners, Jimmy Red, , sobered, , Jimmy Red’s, Florence, Ted Chewning, Chewning, Campbell Coxe, Peter Frank Edwards, Brian Ward, it’s, Ward, ” Ward, Carolina Gold Rice, Ann Marshall, Scott Blackwell, Marshall, It’s, We’re Organizations: CNN, Hurricane, High, Clemson University, Carolina, Jimmy Locations: Hurricane Florence, Darlington County , South Carolina, Charleston, Florence, Colleton, Darlington, South Carolina, Island , South Carolina, Mississippi, Gulf of Mexico, Charleston , South Carolina
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