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Lilly expects the U.S. Food and Drug Administration to decide by the end of this year whether to approve donanemab. The company had previously reported that 24% of the overall donanemab treatment group had brain swelling. The deaths of three trial patients were linked to the treatment, researchers reported. For high tau patients, donanemab was shown to slow disease progression by about 17%, while the benefit was 35% for those with low-to-intermediate tau levels. Both medications are also being studied in large trials to see if they have an impact on delaying onset of Alzheimer's disease symptoms.
Persons: Seth Gale, Brian Snyder, Eli Lilly, Anne White, Lilly, Susan Kohlhaas, Liana Apostolova, White, Liz Coulthard, donanemab, Deena Beasley, Ludwig Burger, Will Dunham, Bill Berkrot, Caroline Humer Organizations: Alzheimer Research, Brigham, Women’s, REUTERS, Alzheimer's Association International, U.S . Food, Drug Administration, Alzheimer’s Research, Indiana University School of Medicine, Doctors, University of Bristol, JAMA, FDA, Alzheimer's Association, Health Organization, New York Stock Exchange, Thomson Locations: Boston , Massachusetts, U.S, Amsterdam, Eisai
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailWhy Alstom and Siemens are ramping up passenger train productionA big boost to the rail industry has come from the Infrastructure Investment and Jobs Act (IIJA), which was passed in 2021 and designates $66 billion to improve the nation's rail system. CNBC visited two of the biggest passenger railcar manufacturers operating in the country: Siemens and Alstom to see how they are ramping up passenger train production and to learn what they see as the future of passenger rail in the U.S.
Organizations: Alstom, Siemens, Infrastructure Investment, Jobs, CNBC Locations: U.S
CNN —If TikTok and Reddit influencers are to be believed, the plant-based compound called berberine can be a replacement for such popular diabetes and weight loss drugs as Ozempic and Wegovy. Is berberine’s weight loss effect meaningful? Berberine may enhance the body’s natural production of GLP-1, or glucagon-like peptide 1, a gastrointestinal hormone that’s used in Ozempic and other new weight loss drugs. However, in terms of its weight loss benefits, they are modest at best,” he said. “Metformin lowers blood sugar, and berberine lowers blood sugar,” Levitt said.
Persons: Berberine, , , Caroline Apovian, Justin Ryder, Ryder, Joshua Levitt, Ashurbanipal, ” Levitt, Gaston Ernesto Gonzalez Avila, Levitt Organizations: CNN, US Food and Drug Administration, Harvard Medical School, Center, Weight Management, Wellness, Brigham, Women’s Hospital, Northwestern University’s Feinberg School of Medicine, BMI, National Library of Medicine, FDA, American Chemical Society Locations: Boston, Chicago, Ayurveda, Hamden , Connecticut
July 3 (Reuters) - The number of U.S. women who died within a year after pregnancy more than doubled between 1999 and 2019, with the highest deaths among Black women, researchers said on Monday. There were an estimated 1,210 maternal deaths in 2019, compared with 505 in 1999, according to a study published in the medical journal JAMA. Unlike previous U.S. studies of maternal mortality, which focused on national trends, the current study analyzed data state-by-state. To the researchers' surprise, Black women had the highest maternal mortality rates in some Northeast states. "Our findings provide important insights on maternal mortality rates leading up to the pandemic, and it's likely that we'll see a continued increase in the risk of maternal mortality across all populations if we analyze data from subsequent years," Bryant said.
Persons: Dr, Allison Bryant, Brigham, Bryant, Nancy Lapid, Michael Erman Organizations: American Indians, Alaska Natives, Blacks, Pacific Islanders, U.S . Centers for Disease Control, Thomson Locations: Alaska, California, Massachusetts, Boston, Midwest, Great
Harvard Admit rate: 4% 10k students Duke University Admit rate: 6% 7k students Amherst College Admit rate: 9% 2k students Carnegie Mellon University Admit rate: 14% 7k students University of California, Berkeley Admit rate: 14% 30k students Boston University Admit rate: 19% 20k students University of North Carolina, Chapel Hill Admit rate: 20% 20k students University of Texas, Austin Admit rate: 29% 40k students University of Florida Admit rate: 30% 30k students Bucknell University Admit rate: 35% 4k students San Diego State University Admit rate: 38% 30k students Binghamton University Admit rate: 44% 10k students University of California, Davis Admit rate: 49% 30k students Clemson University Admit rate: 49% 20k students Stevens Institute of Technology Admit rate: 53% 4k students University of Washington, Seattle Campus Admit rate: 54% 40k students Brigham Young University Admit rate: 59% 30k students CUNY Queens College Admit rate: 61% 20k students Texas A & M University, College Station Admit rate: 64% 60k students University of Pittsburgh Admit rate: 67% 20k students Texas Tech University Admit rate: 68% 30k students Ball State University Admit rate: 68% 10k students Rutgers University, New Brunswick Admit rate: 68% 40k students Purdue University Admit rate: 69% 40k students Louisiana State University Admit rate: 71% 30k students University of Delaware Admit rate: 72% 20k students University of Central Missouri Admit rate: 76% 8k students Mississippi State University Admit rate: 76% 20k students University of Wisconsin, Eau Claire Admit rate: 78% 10k students University of Alabama Admit rate: 79% 30k students University of North Carolina, Charlotte Admit rate: 79% 20k students University of Colorado Boulder Admit rate: 80% 30k students Drexel University Admit rate: 83% 10k students University of Arkansas Admit rate: 83% 20k students University of Cincinnati Admit rate: 85% 30k students University of Texas, Dallas Admit rate: 87% 20k students Suffolk University Admit rate: 88% 4k students Arizona State University Admit rate: 88% 60k students West Chester University of Pennsylvania Admit rate: 89% 10k students Grand Valley State University Admit rate: 92% 20k students University of Kansas Admit rate: 93% 20k students Utah State University Admit rate: 93% 20k students California State University, Sacramento Admit rate: 94% 30k students University of Utah Admit rate: 95% 30k students Kansas State University Admit rate: > 95% 20k students University of Wyoming Admit rate: > 95% 9k students 90% admission rate 80% admission rate 70% admission rate 60% admission rate 50% admission rate 40% admission rate 30% admission rate 20% admission rate 10% admission rate These are America’s major four-year colleges, arranged by their admission rates. Just 6 percent of all college students attend a school with an acceptance rate of 25 percent or less. 56 percent of these college students go to a school that admits at least three-quarters of its applicants. These statistics reveal a simple fact about affirmative action in higher education: It mattered very little for the majority of American college students. But because affirmative action only opened a tiny window of access to America’s most elite institutions, the ruling will make little difference for most college students.
Persons: Richard Arum, Mitchell, Stevens, Quoctrung Bui Mr, Arum, Davis, It’s, Lyndon B Organizations: University of California, Stanford Graduate School of Education, Harvard, Duke University, Amherst College, Carnegie Mellon University, Boston University, University of North, University of Texas, University of Florida, Bucknell University, San Diego State University, Binghamton University, Clemson University, Stevens Institute of Technology, University of Washington, Brigham Young University, CUNY Queens College, Texas, M University, College, University of Pittsburgh, Texas Tech University, Ball State University, Rutgers University, Rutgers University , New, Purdue University, Louisiana State University, University of Delaware, University of Central, Mississippi State University, University of Wisconsin, University of Alabama, University of Colorado Boulder, Drexel University, University of Arkansas, University of Cincinnati, Suffolk University, Arizona State University, West Chester University of Pennsylvania, Valley State University, University of Kansas, Utah State University, California State University, University of Utah, Kansas State University, University of Wyoming, Stanford, Black White, White Black, U.S . Department of Education, Pomona, San, California State University , Los, of California Locations: Irvine, Berkeley, University of North Carolina, Austin, Seattle, Rutgers University ,, Rutgers University , New Brunswick, University of Central Missouri, Eau Claire, Charlotte, Dallas, Sacramento, Cambridge, Palo Alto, America, California, San Francisco State, California State University , Los Angeles
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailHow to prepare the U.S. power grid for the EV boomThe EV revolution could put a major strain on the nation's electric grid, an aging system built for a world that runs on fossil fuels. To upgrade the grid to meet growing electricity demand, the U.S. needs to build a massive amount of new transmission and distribution lines to connect renewable energy resources to population centers. But there are major regulatory hurdles, and the government is not investing near the amount that analysts say we need in order to meet electrification targets.
Locations: U.S
Over half of all new cars sold in the U.S. by 2030 are expected to be electric vehicles. That could put a major strain on our nation's electric grid, an aging system built for a world that runs on fossil fuels. Major grid infrastructure needsCharging electric vehicles is quite electricity intensive. Larger electric vehicles such as the Ford F-150 Lightning would generally use more electricity than a central AC unit in a large home. The utility is tied to a four-year funding cycle for grid infrastructure upgrades, and its last funding request was in 2021.
Persons: That's, we've, Rob Gramlich, Gramlich, Lydia Krefta, Krefta, David Paul Morris, Aram Shumavon, Shumavon, we're, Sen, Joe Manchin, Joe Biden, Tesla Organizations: Rapid Energy, Princeton University, Grid, California Public Utilities Commission, EV, Tesla, Ford, Workers, Power Services, Pacific Gas & Electric, Bloomberg, Getty, Nissan Leaf, Ford Motor Company Locations: U.S, California, Northern, Central California, Healdsburg , California
Loneliness, social isolation linked with early death
  + stars: | 2023-06-19 | by ( Kristen Rogers | ) edition.cnn.com   time to read: +7 min
The new paper, however, is a meta-analysis of 90 studies that had examined the links between loneliness, social isolation and early death among more than 2 million adults. People who experienced social isolation had a 32% higher risk of dying early from any cause compared with those who weren’t socially isolated. Holt-Lunstad was the lead scientist on the US Surgeon General’s recent advisory report on social isolation and loneliness. Broadening social connectionsPeople experiencing social isolation and loneliness should actively seek social support, Wang said. Public health strategies to address loneliness and social isolation, including raising awareness, are also needed, Wang said.
Persons: Turhan Canli, Canli wasn’t, Julianne Holt, wasn’t, Holt, Lunstad, Anthony Ong, Ong wasn’t, ” Holt, Canli, , ” Canli, Fan Wang, , Ong, Wang Organizations: CNN, Stony Brook University, Brigham Young University in, Center, Integrative Developmental, Human Health Labs, Cornell University, , Harbin Medical University Locations: Brigham Young University in Utah, New York, China
“This study captures why obesity is a disease — there are actual changes to the brain,” said Apovian, who was not involved in the study. They wanted to know if that would be different in people with obesity compared to those of normal weight. At the same time, levels of dopamine rose in those at normal weight, signaling that the reward centers of the brain were also activated. Losing weight did not reset the brain in people with obesity, Serlie said. Until science answers these questions, the study emphasizes, once again, that weight stigma has no place in the fight against obesity, Serlie said.
Persons: ’ ”, Caroline Apovian, , Apovian, Sadaf, they’ve, , Mireille Serlie, ” Faroof, ” Serlie, Farooqi, Serlie, it’s, ” Farooqi, Organizations: CNN, Harvard Medical School, Center, Weight Management, Wellness, Brigham, Women’s Hospital, BMI, University of Cambridge, Yale School of Medicine Locations: Boston, New Haven , Connecticut
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailHow Samsung became the world's second biggest advanced chipmakerSamsung may be known for its phones, TVs and appliances, but it's also been the leader in memory chips for more than three decades. Now, as memory prices continue to fall, it's doubling down on manufacturing chips for outside customers, with a $17 billion new chip fab in Texas and new $228 billion cluster in South Korea. CNBC got a rare look inside Samsung's chip business to bring you the untold story of how it became the world's second biggest advanced chipmaker, with plans to catch TSMC.
Persons: it's Organizations: Samsung, CNBC Locations: Texas, South Korea
Carta Healthcare raised a $25 million Series B from backers like health system Memorial Hermann. That puts startups in need of a Series B round in a tough position. Insider got an exclusive look at the pitch deck Carta Healthcare used to raise $25 million in Series B funding. This article was initially published in November 2022 and has been updated in June following the official close of Carta's Series B. Here's the 18-slide presentation Carta Healthcare used to raise $25 million in Series B funding.
Persons: Hermann, Matt Hollingsworth, Brigham, Hollingsworth, Anna Brody, Carta, hasn't Organizations: Healthcare, Investors, Rock Health, Carta, Memorial Hermann Health, UnityPoint, Paramark Ventures, Frist Cressey Ventures, American College of Cardiology, Asset Management Ventures, Innovation, Mass, Maverick Ventures Investment Fund, Storm Ventures Locations: , San Francisco
In this article NVDAQCOM6758.T-JPAMATAMD2330-TW.FKRX300MUAAPL Follow your favorite stocks CREATE FREE ACCOUNTSamsung's $17 billion new chip fab is under construction in Taylor, Texas, on April 19, 2023. CNBC recently went inside Samsung's Austin chip fab, for the first in-depth tour given on camera to a U.S. journalist. Samsung got its start in 1938 as the Samsung Sanghoe Trading Company, founded by Lee Byung-chull in Korea. Just a decade after making its first memory chip, Samsung was coming to market with a version that had 1,000 times the capacity. As consumers rein in their spending in the face of rising inflation, demand for memory chips has weakened sharply.
Persons: Katie Brigham, Jon Taylor, Patel, Jinman Han, Han, Lee Byung, Lee Kun, Geoffrey Cain, weren't, Apple, Cain, Jay Y, Lee, Yoon Suk, Joe Biden, Jonathan Ernst Organizations: AMD, Samsung, Taiwan Semiconductor Manufacturing Company, Intel, they'll, CNBC, Austin, Samsung Sanghoe Trading Company, Samsung Samsung, Samsung Electronics, Samsung TV, Hankook Semiconductor, Apple, Republic of Samsung, Samsung Electronics Pyeongtaek, Reuters Locations: Taylor , Texas, TSMC, U.S, Korea, New Jersey, Silicon Valley, South Korea, Republic of, Austin , Texas, Texas, Austin, Pyeongtaek
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailHow new lithium extraction tech could help meet EV targetsA suite of new, but largely unproven, technologies known as direct lithium extraction could revolutionize lithium mining from brine, making it more efficient and sustainable and eliminating the need for large evaporation ponds. A number of companies including EnergyX, Lilac Solutions, and Standard Lithium are entering the DLE market and getting ready for commercial implementation across South America and the U.S., while automakers like BMW, GM and Ford are investing.
Organizations: EV, Solutions, South, BMW, GM, Ford Locations: South America, U.S
Today, most lithium brine mining takes place in the Salar de Atacama, an expansive salt flat in northern Chile that contains the highest quality lithium brine in the world. EnergyXDoing things differentlyIn a world before electric vehicles, traditional methods of brine mining and hard rock mining more than sufficed to meet global lithium demand. It's the brine resources that are large enough to electrify the vehicle industry," Snydacker said. Lilac Solutions is developing a direct lithium extraction facility in Argentina in partnership with Australian lithium company Lake Resources. Lilac Solutions
Persons: Dave Snydacker, DLE, Amit Patwardhan, Robert Mintak, there's, Snydacker, EnergyX, It's Organizations: Lilac Solutions, Solutions, Bay, Resources Locations: Salar, Atacama, Chile, Arkansas, Salt, Argentina, Bolivia, California , Utah, China, Australian
CNN —When Sam Maya, a beloved husband, father, friend, stockbroker and coach, died by suicide 16 years ago, he left a note. Maya spent nearly a decade writing "Sushi Tuesdays," which aims to humanize the face of suicide. Post Hill PressShe spent nearly a decade writing “Sushi Tuesdays,” beginning with a blog by the same name, an homage to the weekly ritual she created after her husband’s death. When Sam Maya died, Tasheff was a single mother living on a budget in Brooklyn and couldn’t travel to California to visit. Maya continues to honor her Tuesdays with therapy and yoga, a hike with a friend, and sometimes a sushi lunch.
Persons: Sam Maya, Charlotte, Charlotte Maya, Maya, Ashwini, Nadkarni, , , Sam, ” Maya, Gregory Stratz, Tim Stratz, Jason Maya, Parker, Danny Maya, Daniel Stratz, Karen Ray, they’d, The, Jane Doe, Jane, she’s, Jane ”, Bess ”, Katherine Tasheff, Tasheff, swiftness, Daniel, Daniels, , Lauren Kerwin, Kerwin Organizations: CNN, Post, Press, US Centers for Disease Control, CDC, Research, Brigham, Women’s Hospital, Psychological, Karen Ray Photography, Rice University, American Foundation for Suicide Locations: Boston, Maya’s, Brooklyn, California
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailInside the world's largest lithium producerAlbemarle, the world's top producer of lithium and the operator of mines in Australia, Chile and the U.S., says it plans to bring its Kings Mountain, North Carolina mine online by 2027. The company, along with its main competitors SQM and Pilbara, control about 40% of the world's lithium supply, according to KeyBanc Capital Markets. Lithium is a critical mineral in electric vehicle batteries. CNBC got an inside look at Albemarle's operations in the U.S. and Chile.
Persons: Albemarle Organizations: KeyBanc, CNBC Locations: Australia, Chile, U.S, , North Carolina
US stocks rose Thursday as markets await important labor data and eye debt ceiling progress. The Labor Department will release the May employment report on Friday morning. It's one of the last big pieces of economic data before the Fed's June 13-14 policy meeting. Sign up for our newsletter to get the inside scoop on what traders are talking about — delivered daily to your inbox. ET close on Thursday:Elsewhere, bitcoin finished May with its first monthly loss of 2023 as traders navigate a murky macro environment.
Persons: , Louis, James Bullard, Patrick Harker, bitcoin, Brigham Santos Organizations: Labor Department, Service, Federal, Louis Fed, Philadelphia Fed, Lama Locations: St
Brett Keller joined Priceline in 1999 just as the dot-com boom was getting in gear. Brett Keller joined the company in 1999 and rose through the ranks to become CEO in 2016. Keller, 55, who grew up in small-town Idaho, didn't travel much as a kid. And yet, Keller didn't set out to forge a career in the travel industry. We have to keep pushing the travel world in the right direction while continuing to promote travel as much as we can.
Biden taps Bertagnolli to lead National Institutes of Health
  + stars: | 2023-05-15 | by ( ) www.reuters.com   time to read: +1 min
WASHINGTON, May 15 (Reuters) - U.S. President Joe Biden will appoint Monica Bertagnolli, director of the National Cancer Institute, to lead the National Institutes of Health, the White House said on Monday. Bertagnolli will become the second woman to serve as a permanent director of the NIH after a yearlong search to find a permanent replacement for the agency's long-serving leader, Francis Collins. "Dr. Bertagnolli is a world-class physician-scientist whose vision and leadership will ensure NIH continues to be an engine of innovation to improve the health of the American people," Biden said in a statement. Bertagnolli was appointed in October to head the National Cancer Institute, which is a part of NIH, and also served as head of surgical oncology at the Dana-Farber Brigham Cancer Center, one of the nation's top cancer research facilities. Lawrence Tabak has been performing the director duties since December of that year after previously holding the roles of principal deputy director and deputy ethics counselor since 2010 at NIH.
CNN —President Joe Biden will nominate Dr. Monica Bertagnolli, who currently leads the National Cancer Institute, to be the next director of the National Institutes of Health, the White House announced on Monday. Biden called Bertagnolli “a world-class physician-scientist whose vision and leadership will ensure NIH continues to be an engine of innovation to improve the health of the American people,” in a statement Monday. She would lead the country’s medical research agency, overseeing 27 research institutes and centers focused on different areas of medical research, such as cancer, the human genome, as well as allergy and infectious diseases. The nomination to lead NIH marks a fast ascent within the Biden administration for Bertagnolli. In this August 2022 photo, Monica Bertagnolli, newly appointed director of the National Cancer Institute, stands for recognition during remarks by President Joe Biden.
Scott Olson | Getty ImagesRepublican presidential hopeful Vivek Ramaswamy built his White House bid around urging companies to stay out of politics. The messages show Ramaswamy's firm actively engaged with GOP state leaders who have defended the fossil fuel industry and criticized environmentally conscious investment standards. Ramaswamy on Thursday defended the firm's engagement with GOP officials, saying bigger firms BlackRock, Vanguard and State Street have conducted similar practices with state officials across the country. Strive has become one of the more vocal opponents of ESG investing and has gained enough notoriety to challenge the likes of fossil fuel giant ExxonMobil . Ron DeSantis, have often attacked ESG investing standards and corporations that support social causes — an increasingly common refrain within the GOP.
Heather Armstrong, an explosively popular web writer and entrepreneur who, under the name Dooce, was hailed as the queen of the so-called mommy bloggers for giving millions of readers regular intimate glimpses of her joys and challenges in parenthood and marriage, as well as her harrowing struggles with depression, died on Tuesday at her home in Salt Lake City. He said he had found her body in the home. Ms. Armstrong, a lapsed Mormon from Salt Lake City, rose to prominence at the dawn of the personal blog craze of the early 2000s. Her baptism in the field came after she graduated from Brigham Young University in 1997 and moved to Los Angeles, where she taught herself HTML code and took a job at a tech company. She started Dooce.com in 2001, christening it with the nickname she had earned after committing a typo writing the word “dude” in an AOL Instant Messenger chat with friends, according to one of her stories.
Zipline: 2023 CNBC Disruptor 50
  + stars: | 2023-05-09 | by ( Cnbc.Com Staff | ) www.cnbc.com   time to read: +3 min
But with the release of its latest drone, Zipline is spreading its unmanned wings far beyond medicine. Zipline also has relationships with medical providers in the country, and in recent years has conducted long-range medical drone flights in challenging geographies including the Appalachian regions of North Carolina. In 2022, Zipline became the first company to receive FAA Part 135 approval for long-range drone delivery in the U.S., a huge step towards greater domestic expansion. From lunch deliveries with Sweetgreen to health prescriptions from Walmart, Zipline can maneuver peak order times by creating its Zips in a way that automatically redistributes the drones from dock to dock for loading and launching. Zipline has already completed 540,000 deliveries to customers, which is more than what Alphabet and Amazon have delivered combined.
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailHow Chile is shaping the global lithium industryChile contains some of the largest and highest quality lithium-brine resources in the world. And with demand booming for electric vehicles and the lithium-ion batteries that power them, Chile's vast salt flats have become a vital national resource. Now, the government has released its long-awaited national lithium policy, which requires private companies to partner with the state to further develop the country's lithium resources, ushering in a new era for the industry. 21:22 38 minutes ago
The only two lithium companies currently operating in Chile are North Carolina-based Albemarle , the largest lithium producer in the world, and SQM , the No. Chile's lithium is of particular strategic importance to the U.S., which has a free trade agreement with the country but not with neighboring Argentina. The plan calls for the creation of a national lithium company to partner with all private businesses looking to enter the sector. Bags of battery-grade lithium carbonate at La Negra, Albemarle's lithium processing plant near Antofagasta, Chile. Lenny-Pessagno told CNBC in January that Albemarle supports the creation of a state-owned lithium company.
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