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☆ Biogen and Eisai's latest clinical trial just crossed the finish line. Here's why analysts say the results could disrupt the future of Alzheimer's care.
▼ + stars: | 2022-09-28 | by ( Yeji Jesse Lee | ) www.businessinsider.com time to read: +7 min

It's a complicated, debilitating illness and drug companies have struggled for years to come up with viable treatments. On Tuesday September 27, Biogen and Eisai announced that lecanemab slowed the rate of cognitive decline in Alzheimer's patients by 27%. Analysts say that this positive result could lead to it becoming a blockbuster drug for the companies. Other big drug companies such as Roche Holdings and Eli Lilly are pursuing similar treatments, with results expected to come later this year and early next year, respectively. "I think people's confidence in the amyloid hypothesis would go down even further, but ultimately people would wait to see what those other data events show," he said.

After Ukrainian forces stage ambushes and cut off the key access route to the capital, Russian soldiers tell their relatives that the military strategy is failing. … That’s what we’re fucking going to do, it seems. “Frankly speaking, nobody understands why we have to fight this war," Sergey tells his girlfriend. Replay‘I’ll quit at once.’Frustrated by continuous setbacks and fearing for their lives, Russian soldiers say they are fed up with the military. As quickly as they came, the Russian soldiers in northern Kyiv withdrew, regrouped and pivoted east, where Russian-backed separatists have been waging war for over eight years.

Russians trying to avoid getting conscripted to fight in Ukraine appeared to be trying to cross the border into Georgia, Kazakhstan and even remote Mongolia, satellite imagery suggested Monday. Russian border guards didn’t appear to be trying to stop them. The Russians are fleeing to Georgia, Mongolia, Kazakhstan and other countries because they don't require visas. Logvin said he waited 34 hours at the border before he was allowed to enter Georgia. According to Maxar, this satellite image appears to show a traffic jam near the Russian border with Georgia on Sunday.

☆ Kia, once the ‘value’ brand, now has the biggest price markups
▼ + stars: | 2022-09-27 | by ( Peter Valdes-Dapena | ) edition.cnn.com time to read: +6 min

CNN Business —Reversing a century of tradition, most cars now sell for over the manufacturer’s sticker price. It isn’t some luxury or performance brand; it’s Kia, the South Korean car brand usually thought of as a value purchase. On average, Kia cars and SUVs are selling for about 6% over their sticker price, according to data from Edmunds.com. Roughly tied for second, at 4% above sticker price on average, are Honda, Hyundai and the luxury SUV brand Land Rover. Kia Motors AmericaAdding to the pressure is that, while manufacturing slowdowns have hit the whole industry, Kia models are especially hard to find.

☆ Russians flee to Georgia after Putin's mobilisation order
▼ + stars: | 2022-09-26 | by ( ) www.reuters.com time to read: +4 min

The Georgian capital Tbilisi had already seen an influx of around 40,000 Russians since Moscow invaded Ukraine on Feb. 24, according to government statistics. There, they hired a local driver to take them through the border checkpoints and after 24 hours they arrived in Tbilisi. The exact number of people who have left Russia since Putin announced what he called a "partial mobilisation" last Wednesday is unclear. LOCAL RESENTMENTRussians already in Tbilisi saw Putin's mobilisation decree as further vindication of their decisions to flee. More than 200 men who were detained at anti-war protests in Moscow last week were issued draft summons, state media reported.

☆ Ukrainian collaborators who sided with Russian occupation were given top jobs and fancy titles. Now they're being hunted down.
▼ + stars: | 2022-09-23 | by ( Mia Jankowicz | ) www.businessinsider.com time to read: +11 min

Around half the city has fled since Russia occupied the city in February, according to its elected mayor, Ivan Fedorov. On August 5, both Ukrainian and Russian sources reported that Vladimir Saldo has been put into a medically induced coma, citing a suspected poisoning. Saldo had the head of the government in the occupied city of Kherson. The business was owned by Balitsky and formerly had many Russian and Belarusian contracts, according to the BBC's Russian service. More than 1,300 people are under investigation for aiding the Russians in Ukraine, according to Ihor Klymenko, Ukraine's Head of National Police.

☆ A Kremlin ally died falling down the stairs, report says — the latest in a series of unexplained deaths among prominent Russians
▼ + stars: | 2022-09-22 | by ( Mia Jankowicz | ) www.businessinsider.com time to read: +3 min

The Moscow Aviation Institute's former rector died in an accident on Wednesday, the facility said. Local media said Anatoly Gerashchenko, 72, died falling down several flights of stairs. It's the latest in a string of accidental or untimely deaths of top Russian figures. The Moscow Aviation Institute (MAI) university announced the death of Anatoly Gerashchenko, 72, saying he died "as a result of an accident." An unnamed source told Russian newspaper Izvestia that he died on the university's grounds, by falling "from a great height" down several flights of stairs.

☆ Bolsonaro's gun laws arm Brazil's brazen bank thieves
▼ + stars: | 2022-09-21 | by ( Gabriel Stargardter | ) www.reuters.com time to read: +10 min

In July, Reuters reported that Brazil's Federal Police disapproved of Bolsonaro's gun policies, arguing they would put more weapons in the hands of criminals. Of all the weapons now available to Brazil's gun fans, the T4 has emerged as the weapon of choice for its gangsters. A common tactic used by gangs - as seen in the case of Huijsman's T4 - is to steal weapons from CAC permit-holders' homes. On Oct. 31, 2021, Minas Gerais military police and Brazil's Federal Highway Police carried out two raids against alleged bank robbers hiding out near Varginha, killing 26 of them. Marques, the gun expert, said Huijsmans' rifle wouldn't be the last legally acquired firearm to turn up at a crime scene.

☆ Here's what the Federal Reserve's third 75-basis point interest rate hike means for you
▼ + stars: | 2022-09-21 | by ( Jessica Dickler | ) www.cnbc.com time to read: +6 min

The federal funds rate, which is set by the U.S. central bank, is the interest rate at which banks borrow and lend to one another overnight. As the federal funds rate rises, the prime rate does, as well, and your credit card rate follows suit within one or two billing cycles. "A 0% balance transfer credit card may be your best weapon in the battle against credit card debt and rising interest rates," he advised. Federal student loan rates are also fixed, so most borrowers won't be impacted immediately by a rate hike. Of course, anyone with existing education debt should check whether they are eligible for federal student loan forgiveness.

Jars of Nescafe Gold coffee by Nestle are pictured in the supermarket of Nestle headquarters in Vevey, Switzerland, February 13, 2020. Russia's invasion of Ukraine has propelled energy and grain prices to all-time highs, driving up the cost of packaged goods. That has been felt particularly acutely in parts of Asia and North Africa, where people spend a higher proportion of income on food and fuel than in the United States and Europe, prompting some shoppers to stockpile non-perishable items. "Nestle is seeing hoarding with bouillon, to an extent soups, coffee for sure," Al Bitar told Reuters. Several countries in North Africa and Central Asia are suffering recurring shortages of basic necessities.

☆ Video: Bus crash fuels anger toward China's zero-Covid policy
▼ + stars: | 2022-09-20 | by ( ) edition.cnn.com time to read: 1 min

A deadly bus crash in southwestern China has triggered outrage at the country's relentless zero-Covid policy. The bus was carrying 47 people from Guiyang city to a remote county 155 miles (249 kilometers) away, when it overturned and rolled into a ditch, killing 27 people. CNN's Ivan Watson has more.

☆ Another interest rate hike is coming from the Federal Reserve: Here's how it could affect you
▼ + stars: | 2022-09-19 | by ( Jessica Dickler | ) www.cnbc.com time to read: +6 min

The U.S. central bank has already raised interest rates four times this year, for a total of 2.25 percentage points. As the federal funds rate rises, the prime rate does as well, and credit card rates follow suit. Student loans The interest rate on federal student loans taken out for the 2022-2023 academic year already rose to 4.99%, up from 3.73% last year and 2.75% in 2020-2021. It won't budge until next summer: Congress sets the rate for federal student loans each May for the upcoming academic year based on the 10-year Treasury rate. Of course, anyone with existing education debt should check whether they are eligible for federal student loan forgiveness.

☆ Lawyers representing migrants dumped on Martha's Vineyard want Florida Gov. DeSantis criminally investigated over the 'stunt'
▼ + stars: | 2022-09-19 | by ( Natalie Musumeci | ) www.businessinsider.com time to read: +4 min

Attorneys for the migrants dumped on Martha's Vineyard want a criminal probe into the incident. Last week, 50 migrants were flown to Martha's Vineyard in a move orchestrated by Florida Gov. Last week, 50 undocumented Venezuelan immigrants were flown on two chartered planes from Texas to Martha's Vineyard in a move that was organized by DeSantis. "It was only when the flight was in mid-air that they were informed they would be flown to Martha's Vineyard, rather than to Boston as many had been told," they wrote in their letters. We are in touch with our federal and state partners, along with attorneys representing the migrants, as we gather facts and evaluate all legal options."

☆ Biogen's latest clinical trial is inching towards the finish line. Here's why analysts say the results could disrupt the future of Alzheimer's care.
▼ + stars: | 2022-09-19 | by ( Yeji Jesse Lee | ) www.businessinsider.com time to read: +7 min

It's a complicated, debilitating illness and drug companies have struggled for years to come up with viable treatments. Other big drug companies such as Roche Holdings and Eli Lilly are pursuing similar treatments, with results expected to come later this year and early next year, respectively. "I think people's confidence in the amyloid hypothesis would go down even further, but ultimately people would wait to see what those other data events show," he said. Negative results might give a boost to companies that are exploring alternate ways to treat Alzheimer's disease. And though Biogen's drug is furthest along in development, it's far from being the only treatment being tested for Alzheimer's.

☆ Modi tells Putin: Now is not the time for war (September 2022)
▼ + stars: | 2022-09-17 | by ( ) edition.cnn.com time to read: 1 min

During a televised interview with Russian President Vladimir Putin, Indian Prime Minister Narendra Modi voiced his concerns about the war in Ukraine and urged Putin to consider moving "on the path of peace." CNN's Ivan Watson and Kim Brunhuber discuss the exchange.

DeSantis claimed credit for a pair of chartered flights on Wednesday that carried around 50 migrants to Martha's Vineyard, Massachusetts, as part of a broader Republican effort to shift responsibility for border crossers to Democratic leaders. "There may be more flights, there may be buses," he said to cheers and applause from backers in the crowd. The state paid $615,000 to Vertol Systems Company Inc, an aviation business, on Sept. 8 as part of a "relocation program of unauthorized aliens," Florida state data showed. The flights to Martha's Vineyard follow a busing effort by Texas Governor Greg Abbott, another Republican, that has sent more than 10,000 migrants to the Democrat-controlled cities of Washington, New York and Chicago since April. The Republican governor of Arizona also has sent more than 1,800 migrants to Washington.

☆ Xi and Putin met for the first time since the war. Hear what they discussed
▼ + stars: | 2022-09-16 | by ( ) edition.cnn.com time to read: 1 min

President Vladimir Putin addressed China's questions and concerns about the war in Ukraine during a regional summit on Thursday. This is the first time Putin and Chinese President Xi Jinping have met since Russia's invasion over six months ago. CNN's Ivan Watson reports.

☆ Ukraine is launching shells filled with flyers telling Russian troops they're 'cannon fodder' to convince them to give up
▼ + stars: | 2022-09-14 | by ( Rebecca Cohen | ) www.businessinsider.com time to read: +3 min

Ukrainian troops are launching shells filled with flyers to convince Russian troops to surrender. Surrender to Armed Forces of Ukraine," the flyers said, according to the Associated Press. In the past week, Ukrainian forces have turned up the pressure on Russian troops in a blistering counteroffensive that has forced some Russian units into retreat. Russian troops have been pulling out of Kharkiv and Melitopol as well, the AP reported, citing reports from the latter city's mayor. Melitopol Mayor Ivan Fedorov reportedly said on Telegram the Russian troops were headed toward Crimea.

☆ 2 of Russia's most modern multi-role fighters are leading Putin's air war over Ukraine
▼ + stars: | 2022-09-14 | by ( Sebastian Roblin | ) www.businessinsider.com time to read: +15 min

Two of Russia's most modern fighters have led its air war over Ukraine: the Su-30SM and the Su-35S. Two of Russia's most modern multi-role fighters have spearheaded Moscow's air war over Ukraine: the two-seat Sukhoi Su-30SM (code-named Flanker-H by NATO) and its successor, the single-seat Su-35S Flanker-E. Su-35S units active in UkraineSu-35S jet fighter of the Russian Air Force taking off, Kubinka, Russia. Artyom Anikeev/Stocktrek Images via Getty ImagesThe Russian Air Force (VKS) is currently receiving the last of 128 Su-35s ordered, most now committed to the war in Ukraine. Russia evidently lacks enough longer-range/endurance surveillance and combat drones to hunt Ukrainian air defense assets through laborious optical scanning.

☆ Judge OKs NY weapons ban in Times Square and other 'sensitive' places — but calls the underlying law 'doomed'
▼ + stars: | 2022-09-01 | by ( Laura Italiano | ) www.businessinsider.com time to read: +7 min

A judge let New York ban guns in 'sensitive' locations, but called the underlying law legally 'doomed.' Gun lobbies are fighting the NY law, enacted after a June Supreme Court decision expanded gun rights. The law bans guns in "sensitive" places like Times Square, parks, theaters, and houses of worship, and re-tightens concealed carry permit restrictions that had been loosened by the Supreme Court in June. But in the Bruen case, the Supreme Court found any such limits on the right to "bear arms" unconstitutional. Both gun lobby groups promised to continue to fight the New York law.

☆ These cloud startups were pandemic darlings. Now the downturn is helping giants like Google and Microsoft gobble them up.
▼ + stars: | 2022-08-29 | by ( Paayal Zaveri | ) www.businessinsider.com time to read: +10 min

Productivity startups boomed as a result, but the downturn will give large suites an advantage. Only productivity tools that carve out new niches or address new challenges will have a chance. Startups building new categories are more likely to surviveWhile the downturn makes it harder for productivity and collaboration startups to grow, experts say it's not impossible. Many of the most popular productivity startups address collaboration problems that aren't solved by the existing software tools or are creating a new category of workplace tools. Companies like Miro, Figma, and Canva are creating a new category of visual collaboration tools aimed at remote teams.

☆ The Ayahuasca Diaries
▼ + stars: | 2022-06-26 | by ( Mattathias Schwartz | ) www.businessinsider.com time to read: +37 min

But please understand: I didn't drink ayahuasca so I could write an article about it. I wrote an article about it so I could drink ayahuasca. I was desperate to drink ayahuasca — I had been for several months, in fact — and the formality of an assignment would help me out at home. Instead, a friend of a friend linked me up with an ayahuasca sangha, a Buddhist word for a spiritual community. I thought of my old friend, Scott, who, many years before, had declined an opportunity to drink ayahuasca.

☆ How the Russian officer elite was decimated in Ukraine – 29 generals and commanders who were killed in action
▼ + stars: | 2022-05-01 | by ( Alia Shoaib | ) www.businessinsider.com time to read: +17 min

Vitaly GerasimovMaj. Gen. Vitaly Gerasimov became the second senior Russian commander reported to be killed after Ukrainian military intelligence claimed he was shot dead in Kharkiv. Ivan GrishinColonel Ivan Grishin, commander of Russia's 49th Anti-Aircraft Missile Brigade, died in Ukraine, according to the Armed Forces of Ukraine. Vyacheslav SavinovLieutenant Colonel Vyacheslav Savinov, who headed Russian artillery intelligence, was killed in Ukraine, a Russian artillery school confirmed. A damaged Russian military vehicle is seen after Russian Forces withdrawal as Russia-Ukraine war continues in Izium, Kharkiv Oblast, Ukraine on September 14, 2022. The Ukrainian military said that Botashev was killed when a Russian Su-25 attack aircraft was shot down over the Lugansk region.

Persons: Михаил Ведерников

CNN —Last month, Ukraine’s Vladyslav Heraskevych was a skeleton racer hurtling his way around the Yanqing Sliding Centre at the Beijing Winter Olympics. Heraskevych holds a sign with a message reading 'No war in Ukraine' during the Beijing 2022 Winter Olympics in February. Till the end, till the 24th of February, all Ukraine and the whole world expects that world war doesn’t start – it’s an absolutely crazy feeling. “I can’t understand why they stay quiet or why they support this war,” Heraskevych said. “They are very powerful tool of Russian politics and propaganda and when these people support war, a lot of people in Russia also start to support this war,” Heraskevych said.

☆ Science says parents of successful kids have these 26 things in common
▼ + stars: | 2022-02-07 | by ( Marguerite Ward | Rachel Gillett | ) www.businessinsider.com time to read: +24 min

Here's what parents of successful kids have in common, according to research. Children with parents who stepped in to provide instructions frequently displayed more difficulty regulating their emotions later, the researchers wrote. "Too much direct engagement can come at a cost to kids' abilities to control their own attention, behavior and emotions. When parents let kids take the lead in their interactions, children practice self-regulation skills and build independence," Obradović wrote in the study. The parents tend to take parental leave.

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