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The 4.8-magnitude earthquake on the East Coast Friday came from ancient dormant faults. The East Coast, however, is located in the middle of a plate and doesn't experience much of that movement. NOAAInstead, East Coast quakes come from stress that builds up on those ancient fault lines. The glaciers heavily weighed down and compressed the northern part of the East Coast. Though that weight has been lifted for more than 10,000 years, the Earth's crust is still rising back to its former shape.
Persons: , Jessica Jobe, Matt Rourke, Lingsen Meng, George Rose, Jobe, Ben Fernando, Johns Hopkins, Meng, Fernando, It's Organizations: East, Service, Geological Survey, UCLA Locations: East Coast, New Jersey, Mill, Lebanon , New Jersey, West, Hot Springs , North Carolina, West Coast, East, Johns, North America
Dark energy was assumed to be a constant force in the universe, both currently and throughout cosmic history. He shared the 2011 Nobel Prize in Physics with two other astronomers for the discovery of dark energy, but was not involved in this new study. “It may be the first real clue we have gotten about the nature of dark energy in 25 years,” he said. That conclusion, if confirmed, could liberate astronomers — and the rest of us — from a longstanding, grim prediction about the ultimate fate of the universe. Instead, it seems, dark energy is capable of changing course and pointing the cosmos toward a richer future.
Persons: , Biden, , Adam Riess, Organizations: Johns Hopkins University, Telescope Science Locations: Baltimore
Prenosis' tool, called Sepsis ImmunoScore, uses 22 different parameters like temperature, heart rate and cell counts to help clinicians assess a patient's risk of sepsis, the company told CNBC. While Prenosis is the first company to receive FDA approval for its AI diagnostic tool for sepsis, several organizations have built and released similar solutions. Epic's sepsis model is used in hundreds of hospitals across the U.S., according to a 2021 study published in JAMA Internal Medicine. Even so, Epic reportedly overhauled its sepsis model the following year in an attempt to improve its performance, according to Stat News. Prenosis said it worked to demonstrate the safety and efficacy of Sepsis ImmunoScore to the FDA for around 18 months.
Persons: ImmunoScore, Prenosis Organizations: U.S . Food, Drug Administration, Wednesday, Centers for Disease Control, CNBC, Johns Hopkins University, Nature Medicine, Systems, Stat News, FDA Locations: U.S, White Oak , Maryland, Chicago
Are nicotine pouches better than vaping? Zyn, among other brands of nicotine pouches such as Rogue, On! However, FDA officials have allowed the nontobacco nicotine product to stay on the market while the application is under review. Nicotine pouches have varying degrees of nicotine strength; 3 or 6 milligrams per pouch is most common, but some brands have pouches that contain upward of 28 milligrams. What’s more, the Zyn nicotine pouches come in a variety of flavors, including cool mint, wintergreen, coffee and cinnamon, that could be appealing to younger people.
Persons: Philip Morris, Chuck Schumer, , Kecia Christensen, , ’ ”, Christensen, Philip Morris International’s, ” Philip Morris, Meghan Moran, ” Moran, Brian King, Yanfang Ren, ” Ren, Moran Organizations: CNN, Philip Morris International, Facebook, Federal Trade Commission, Food and Drug Administration, American Cancer Society, Nebraska Medicine, FDA, National Cancer Institute, CDC, Centers for Disease Control, ” Philip Morris International, Swedish, Johns Hopkins Bloomberg School of Public Health, Tobacco Survey, FDA’s Center for Tobacco Products, University of Rochester Eastman Institute for Oral Health, Philip Locations: United States, , Baltimore, New York, Mayo
Mitch McConnell is stepping down from being Senate GOP leader after more than 17 years in the job. John Thune and John Cornyn are already campaigning for the job, but others could jump in later. AdvertisementMitch McConnell's reign as Senate Republican leader is set to end next January, capping off what will ultimately be an 18-year tenure — the longest of any Senate leader in American history. John Thune and John Cornyn. McConnell's penchant for bipartisanship and support for Ukraine aid in particular have rankled a small segment of GOP senators, and that cohort could be influential in determining who GOP senators succeed in November.
Persons: Mitch McConnell, John Thune, John Cornyn, , Mitch McConnell's, Johns Organizations: GOP, Service, Republican, Kentucky Republican, Republicans Locations: Sens, Ukraine
Baltimore’s regional economy has a lot going for it such as low unemployment and low inflation. That’s well below the national rate of 3.9% in February and ranks 43rd out of 389 regions across the country with more than one million residents. Low inflationThe US economy is still dealing with high inflation, but that’s not much of a problem for the Baltimore metro. Inflation in Baltimore slowed dramatically last year from April to June, falling to a 2.8% annual rise from April’s 5.3%. Like across the country, rising energy prices have recently pushed up overall inflation in the Baltimore metro.
Persons: Francis Scott Key, Prince, it’ll, Matt Rourke, Matt Jaffe, , ” Jaffe, that’s, That’s, ” Christina DePasquale, Johns, Freddie Mac Organizations: Washington CNN, CNN, Towson, Labor Department, Washington D.C, U.S, Baltimore, Johns Hopkins Carey Business School, National Association of Realtors, NAR, Fed Locations: Baltimore, Port, Baltimore County, Columbia, Boston, Orlando, Atlanta, Washington, Dundalk, Md
John Barth, who, believing that the old literary conventions were exhausted, extended the limits of storytelling with imaginative and intricately woven novels like “The Sot-Weed Factor” and “Giles Goat-Boy,” died on Tuesday. His death was confirmed by Rachel Wallach, who works in communications at Johns Hopkins University, where Mr. Barth was an emeritus professor of English and creative writing. She said she did not have further details. Mr. Barth was 30 when he published his sprawling third novel, the boisterous “The Sot-Weed Factor” (1960). It projected him into the ranks of the country’s most innovative writers, drawing comparisons to contemporaries like Thomas Pynchon, Jorge Luis Borges and Vladimir Nabokov.
Persons: John Barth, “ Giles, , Rachel Wallach, Barth, Thomas Pynchon, Jorge Luis Borges, Vladimir Nabokov Organizations: Johns Hopkins University
CNN —About 1 in every 10 people in the US who uses Adderall or similar combination drugs to treat attention-deficit/hyperactivity disorder (ADHD) has been affected by an ongoing shortage, a new analysis suggests. The US Food and Drug Administration announced that Adderall was in shortage in mid-October 2022, and the share of people with ADHD who filled their prescriptions for Adderall and related medications plunged in the following months. Patients were considered eligible for a monthly prescription fill if they had filled one within the previous two years. Prescriptions for medications used to treat ADHD surged during the Covid-19 pandemic, especially among young adults and women, one study found. But it’s been about a year and a half since she’s been able to fill her Adderall prescription in a “totally uneventful” way, she said.
Persons: Adderall, Robert Califf, Anne Milgram, David Goodman, , Mary Beth King, it’s, she’s, ” King, King, ” Goodman, John Mitchell, ” Mitchell, they’re, ’ ”, , , Dr, Sanjay Gupta, hasn’t Organizations: CNN, US Food and Drug Administration, Drug, of Psychiatry, Behavioral Sciences, Johns Hopkins School of Medicine, American Professional Society, New, Psychiatric Institute, Columbia University Irving Medical Center, Duke University School of Medicine, Get CNN, CNN Health Locations: Sweden
CNN —Israeli Prime Minister Benjamin Netanyahu will have surgery under full anesthesia for a hernia, his office said in a statement. Israel’s deputy prime minister and justice minister, Yariv Levin, will step in for Netanyahu while he is incapacitated. Yariv Levin, left, will step in for the Prime Minister while he is incapacitated. A health scare last summer ended with the Israeli leader being fitted for a pacemaker to fix a transient heart block. Netanyahu previously had a hernia in 2013 that also required surgery.
Persons: Benjamin Netanyahu, Netanyahu, Yariv Levin, Abir Organizations: CNN, Israeli, Getty, Johns Hopkins Medicine Locations: Gaza, Abir Sultan, AFP, Israel, Cairo
(AP) — Rebuilding Baltimore’s collapsed Francis Scott Key Bridge could take anywhere from 18 months to several years, experts say, while the cost could be at least $400 million — or more than twice that. Realistically, the project could take five to seven years, according to Ben Schafer, an engineering professor at Johns Hopkins University. “The lead time on air conditioning equipment right now for a home renovation is like 16 months, right?" But experts say it's better to look to more recent bridge disasters for a sense of how quickly reconstruction may happen. Hota GangaRao, a West Virginia University engineering professor, said the project could cost as little as $400 million.
Persons: Baltimore’s, Francis Scott Key, Ben Schafer, , Schafer, they’re, Dali, Jim Tymon, ” Tymon, Tymon, Joe Biden, Minnesota Sen, Amy Klobuchar, ” Klobuchar, ” Badie, Badie, Hota, That’s, ” GangaRao, ” Norma Jean Mattei, Organizations: Johns Hopkins University, George Washington University, Sunshine, American Association of State, Transportation, West Virginia University, The University of New Locations: ANNAPOLIS, Md, Baltimore, Tampa Bay, Minnesota, Mississippi, Maryland, The University of New Orleans
Erin Schaff/The New York TimesForce of Ship Collision Was on the Scale of a Rocket LaunchThe container ship Dali appeared to move sluggishly before striking the Francis Scott Key Bridge in Baltimore on Tuesday. Experts disagreed on whether it was reasonable for any bridge pier to withstand a direct collision with a massive container ship. F = ma force mass acceleration F = ma force mass accelerationOur first task, and a major source of uncertainty, was finding those numbers. F= (100,000 to 195,000 metric tons) × (7.8 mph - 2.5 mph) / 38 seconds mass acceleration F= (100,000 to 195,000 metric tons) × (7.8 mph - 2.5 mph) / 38 seconds mass acceleration For the actual calculation, we used metric units. We tried one more method: using a formula to calculate the ship collision force published by the American Association of State Highway and Transportation Officials, the industry organization that publishes bridge safety standards.
Persons: Erin Schaff, Dali, Francis Scott Key, , , Ben Schafer, Nii, Sherif El, Themistoklis Sapsis, Tawil Organizations: The New York Times Force, Empire, Saturn, Johns Hopkins, University of Maryland, University of Michigan, M.I.T, American Association of State, Transportation, U.S . Army Corps, Engineers, Reuters, Sunshine Skyway Locations: Baltimore, Dali, Tampa Bay, Florida
Ron DeSantis signed a Florida bill prohibiting children under 14 from joining social media. Parents can sue social media companies for $10k for not promptly deleting an account of a child under 14. AdvertisementA new Florida bill could open the floodgates for parents to sue for up to $10,000 if social media companies fail to remove flagged accounts of their underage children in a timely manner. AdvertisementNetChoice is a major coalition of social media platforms opposing these restrictions and it includes TikTok, Meta, Google, and X among others. The latest bill follows a series of legislative attempts from the government to place restrictions on social media.
Persons: Ron DeSantis, , Paul Renner, DeSantis, Stacey Lee, Johns, Lee, Krista Chavez, NetChoice, Chavez, Carl Szabo, Szabo, It's Organizations: NetChoice LLC, Service, Florida Gov, Florida House, Companies, Johns Hopkins Carey Business School, Google, BI, Gov Locations: Florida, California , Utah , Ohio, Arkansas, California, Ohio, Utah hasn't
One of the most helpful things to do might be to get some exercise, according to a new study. “It gives us an idea of something that maybe we don’t always think about for treatment of insomnia,” Paruthi said. Regular exercise was associated with significantly better sleep, the study showed. There are plenty of reasons why physical activity may help in getting a good night’s rest. Physical activity helps regulate the body’s internal clock and promotes deeper, more restorative sleep,” Björnsdóttir said.
Persons: , Erla, sleepiness, David Neubauer, ” Björnsdóttir, Shalini Paruthi, ” Paruthi, Neubauer, Paruthi Organizations: CNN’s, CNN, Reykjavik University, Johns Hopkins University School of Medicine, Saint Louis University School of Medicine, American Academy of Sleep
These proteins cause the walls of a person’s blood vessels to keep growing and thicken over time. As the blood vessels narrow, the heart is forced to work harder to pump blood to the lungs. Treatment with a combination of drugs that dilate, or relax, blood vessels can improve this outlook, but they are not a cure. Both groups were also taking the standard medications for the condition, which help relax blood vessels to improve blood flow. But Galiatsatos said that as promising as the drug looks, there are still many unknowns, including whether the drug will benefit all PAH patients equally.
Persons: Katrina Barry, Barry, , , Winrevair, Merck Winrevair, Vallerie McLaughlin, Panagis, Galiatsatos, isn’t, ” Barry, I’m, fanny, She’s, sotatercept, PAH, Sotatercept, “ There’s, Kristin Highland, Highland, ” Merck, Merck, Dr, Sanjay Gupta, Aaron Waxman, Barry’s, he’s, they’ve, Johnson –, Waxman, “ I’ve, “ It’s, who’ve Organizations: CNN, American Lung Association, US Food and Drug Administration, Merck, FDA, University of Michigan, PAH, Johns Hopkins Bayview Medical Center, New England, of Medicine, Cleveland Clinic, Institute, Clinical, CNN Health, Brigham, Women’s Hospital, Johnson Locations: PAH, American, Greece, Boston
Read previewMoving into their 360-square-foot floating home a year ago was a dream come true for Sarah Spiro and Brandon Jones. In 2023, there were 70 floating home sales reported on the Regional Multiple Listing Service, or RMLS, which covers the Portland area and a significant part of northwest Oregon, Portland Floating Homes real-estate broker John McPherson told BI. Lily and Dylan Rose moved onto their houseboat on Lake Union in Seattle in June 2019. AdvertisementHome insurance for a floating house tends to be about double what it is for a regular house on land, McPherson said. Additionally, the float — the part of the floating house that's equivalent to a foundation — deteriorates over time, McPherson said.
Persons: , Sarah Spiro, Brandon Jones, Spiro, keepingafloatwiththejoneses Spiro, Jones, keepingafloatwiththejoneses, Adam Lind, @adam.floatinghome, It's, John McPherson, Lily, Dylan Rose, Elizabeth Earle, BI's Jordan Pandy, Earle, Elizabeth Earle Earle's, McPherson, Daryl Fairweather, Redfin's, Realtor.com, Hannah Jones, it's, Laura Woodley, Woodley, isn't, Kate Fincham, Fincham, Lily Rose, Dylan, Rose, she's Organizations: Service, Business, Portland Floating Homes, Realtor.com, Union, Trust, England & Wales, Lake Union Locations: Fontana Lake, North Carolina, Portland, Oregon, Seattle, Sausalito , California, Johns Island , South Carolina, England, Bluffers Park, Toronto, Lake, Boston
A Black couple who claimed an appraisal company undervalued their Baltimore home based on their race have settled their lawsuit against their mortgage lender, loanDepot, which has agreed to a number of sweeping policy changes that could offer significant relief to homeowners who allege racially biased appraisals in the future. Dr. Connolly and Dr. Mott, both faculty members at Johns Hopkins University, sued loanDepot, a mortgage lender, as well as Shane Lanham, an appraiser hired by a contractor for the company, in August 2022. A year earlier, the couple had opened their home to Mr. Lanham, who is white, for an appraisal, and he put the value of their four-bedroom house in Baltimore’s Homeland neighborhood at $472,000. After the couple stripped their home of family photographs and had a white colleague pose as the homeowner, an action known as “whitewashing,” a second appraiser offered a value of $750,000. The couple said that the difference in value — nearly $300,000 higher — came because the second appraiser believed that the home’s owners were white.
Persons: Nathan Connolly, Shani Mott, . Connolly, Mott, loanDepot, Shane Lanham, Lanham, Organizations: Johns Hopkins University Locations: Baltimore
Shani Mott, a scholar of Black studies at Johns Hopkins University whose examinations of race and power in America extended beyond the classroom to her employer, her city and even her own home, has died in Baltimore. She died of adrenal cancer on March 12, said her husband, Nathan Connolly, a professor of history at Johns Hopkins. Though Dr. Mott spent her career in some of academia’s elite spaces, she was firmly committed to the idea that scholarship should be grounded and tangible, not succumbing to ivory tower abstraction. She encouraged students to turn a critical eye to their own backgrounds and to the realities of the world around them. In a city like Baltimore, with its complicated and often cruel racial history, there was plenty to scrutinize.
Persons: Shani Mott, Nathan Connolly, Johns Hopkins, Mott, Mott’s, Organizations: Johns Hopkins University, Johns, university’s, Africana Studies Locations: America, Baltimore
Coming into effect on Saturday, the law introduces 39 new national security crimes, adding to an already powerful national security law that was directly imposed by Beijing on Hong Kong in 2020 after huge and sometimes violent democracy protests the year before. Hong Kong’s Chief Executive Lee described it as a “historical moment for Hong Kong.”Lawmakers attend a meeting for Basic Law Article 23 legislation at the Legislative Council on March 19, 2024 in Hong Kong, China. They argue their legislation is similar to other national security laws around the world. “This will surely increase the doubt, anxiety, and uncertainty of foreign businesses in Hong Kong.”In mainland China, national security laws have often ensnared both local and foreign businesses in opaque investigations. That is something Emily Lau, a former pro-democracy lawmaker, also worries about, that what made Hong Kong distinct is fast fading.
Persons: , John Lee, Hong, Lee, Chen Yongnuo, , Hong Kong’s, Eric Lai, Lai, ” Lai, Hung Ho, fung, Capvision, Sarah Brooks, , ” Brooks, ” Johannes Hack, Emily Lau, I’ve Organizations: Hong Kong CNN, Hong, ” Lawmakers, Legislative, China News Service, China’s Communist Party, CNN, Georgetown Center, Asian Law, Johns Hopkins University, Amnesty International, German Chamber of Commerce, Hong Kong Locations: Hong Kong, Hong Kong’s, Beijing, China, Amnesty International China, , Hong
Pop art: Explaining it’s enduring appeal
  + stars: | 2024-03-18 | by ( Christian House | ) edition.cnn.com   time to read: +6 min
CNN —As accidental adverts for art shows go, a giant pooch made of flowers is a crowd pleaser. Outside the Guggenheim Bilbao in northern Spain, Jeff Koons’ much-loved flower 1992 sculpture “Puppy,” shows how Pop art — that high kick of counter-intuitive artistic expression so often equated with the 1960s — never really went away. The Pop baton has been handed over numerous times in art history. The Guggenheim Museum was pivotal to the development of the movement, both in terms of its fame and its art historical importance. The show features works by many American Pop art A-listers like Roy Lichtenstein (above).
Persons: Jeff Koons ’, , Koons, Andy Warhol, Roy Lichtenstein, Robert Rauschenberg —, Lauren Hinkson, ” Erika Ede, , Claes Oldenburg, Maurizio Cattelan, Pinocchio, Lucia Hierro, Warhol, Lichtenstein, Rauschenberg, Jasper Johns, James Rosenquist, Jim Dine, Coosje van Bruggen, Frank Lloyd Wright, Erika Ede, Joan Young, “ Andy Warhol, , Lucía Hierro, Hierro, Lucía Guzmán, , “ I’ve, begonias, Pop Organizations: CNN, Guggenheim, Highland, Guggenheim Museum Locations: Spain, York, Manhattan, Bilbao, Dominican American, New York, Hierro
download the appSign up to get the inside scoop on today’s biggest stories in markets, tech, and business — delivered daily. Read previewCeline Dion said she was "determined to one day get back onto the stage" while reflecting on her stiff-person syndrome diagnosis. "Today the world recognizes International SPS Awareness Day," Dion, 55, wrote. "As many of you know, in the fall of 2022, I was diagnosed with Stiff Person Syndrome (SPS)," she continued. Celine Dion, pictured here in 2015, hopes to be able to perform again in the future.
Persons: , Celine Dion, Dion, René, Charles, Nelson, Eddy, she'd, Denise Truscello, I'm, Taylor Swift Organizations: Service, Business, Johns Hopkins Medicine
The Supreme Court will hear arguments on Monday in a case that involves the Biden administration’s efforts to communicate with social media sites about posts officials believed made false or misleading claims about Covid-19 vaccines and the pandemic. While the case primarily focuses on a debate around free speech, it also spotlights the potential harms of medical misinformation — which experts say has become increasingly complex and difficult to identify. “It’s all changing really fast, and it’s even harder for the average person to filter out,” said Dr. Anish Agarwal, an emergency physician in Philadelphia. Health hacks not backed by science have spread widely on social media platforms. And rapid developments in artificial intelligence have made it even harder for people to tell what’s true and what’s false online.
Persons: Biden, , Anish Agarwal, Tara Kirk Sell Organizations: Johns Hopkins Center for Health Security Locations: Covid, Philadelphia
A man wearing a Diego Maradona t-shirt walks by the Argentine Central Bank on November 30, 2023 in Buenos Aires, Argentina. Data published Tuesday by the country's statistical office showed that Argentina's 12-month inflation rate through February rose to 276.2%, reaffirming Argentina's position as having the world's worst inflation. Hanke said that in 1999 he had drafted a law at the request of former President Carlos Menem that would have dollarized Argentina's economy. Advocates of dollarizing Argentina's economy say the switch could help the country tame skyrocketing inflation and bring an end to its boom-and-bust cycle. Ecuador and Panama are two notable examples of countries that have previously dollarized their economies, but no country of Argentina's size has previously shifted to the U.S. dollar.
Persons: Diego Maradona, Tomas Cuesta, Javier Milei, Steve Hanke, Milei, Hanke, CNBC's, Carlos Menem, he'd, Argentina Javier Milei, Donald Trump Organizations: Argentine Central Bank, Getty, Monday, Johns Hopkins University, Argentine Congress, International Monetary Fund, CNBC, U.S . Locations: Buenos Aires, Argentina, London, Ecuador, Panama
Link icon An image of a chain link. It symobilizes a website link url. Link icon An image of a chain link. Copy LinkTwitter LinkedIn icon LinkedIn Fliboard icon A stylized letter F. Flipboard Link icon An image of a chain link. Twitter LinkedIn icon LinkedIn Fliboard icon A stylized letter F. Flipboard Link icon An image of a chain link.
Only 3% to 5% of people who are diagnosed with this type of brain tumor will be alive three years later. Now, an experimental therapy that reprograms a person’s own immune cells to attack these tumors is showing some exciting promise. Doctors first harvested immune fighters called T-cells from his blood and then genetically modified them in a lab so they’d recognize and bind to specific proteins on the surface of the brain tumor cells. After a single 10-milliliter infusion of about 10 million CAR-T cells, Fraser’s tumor began to shrink. Three-quarters of the participants had had their brain tumors come back at least twice.
Persons: , Otis Brawley, , they’ll, ” Brawley, Tom Fraser, Brigham, Debbie Fraser, Fraser, He’s, Marcela Maus, ” Fraser, Maus, , ” Maus, Christine Brown, ’ Brown, ” Brown, hasn’t, Brown, Dr, Donald O’Rourke, “ They’re, O’Rourke, ” O’Rourke, Sanjay Gupta, you’re, they’re, it’s Organizations: CNN, Johns Hopkins University, American Cancer Society, City of Hope Cancer Center, University of Pennsylvania, Massachusetts General, Mass, New England, of Medicine, Doctors, Mass General Cancer Center, Tv3, Cell Therapeutics Research, of, Nature, Penn, Excellence, University of Pennsylvania Perlman School of Medicine, CNN Health Locations: City, Duarte , California, Massachusetts, Rochester , New York, Boston, of Hope, Hope
The “X-Men: Apocalypse” star, 43, wrote in an Instagram post Wednesday that she was diagnosed with breast cancer last year and would not have discovered it if her physician, Dr. Thaïs Aliabadi, had not calculated her breast cancer risk score. A breast cancer risk assessment tool uses a statistical model to estimate a woman’s risk of developing breast cancer over the next five years as well as over her lifetime, or up to about age 90, according to the National Cancer Institute. Two models are commonly used as breast cancer risk assessment tools: the Gail Model and the Tyrer-Cuzick Risk Assessment Calculator. An online version of the breast cancer risk assessment tool, using the Gail Model, is available for anyone to take at bcrisktool.cancer.gov. In fact, some women who do not develop breast cancer have higher risk estimates than some women who do develop breast cancer,” according to the National Cancer Institute’s website.
Persons: Olivia Munn’s, Thaïs Aliabadi, Aliabadi, Munn, Gail, Jennifer Plichta, , ” Plichta, they’re, , Plichta, I’ve, they’ve, Otis Brawley, ” Brawley, Larry Norton, Evelyn H, ” Norton, Robert Smith, Ruth Oratz, NYU Langone Health’s, Dr, Sanjay Gupta, ” Oratz Organizations: CNN, National Cancer Institute, National Cancer, Duke Cancer Institute, Johns Hopkins University, Lauder Breast Center, Memorial Sloan Kettering Cancer Center, American Cancer Society, US Preventive Services Task Force, NYU, Cancer Center, NYU Grossman School of Medicine, CNN Health Locations: United States, Durham , North Carolina
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