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If successful, Merck could begin marketing the new formulation within a few years, a top Merck executive told Reuters. "The clock for that patent would start ticking from the time we would get that patent approved." Drug patents have a guaranteed term of exclusivity for 20 years after receiving a patent under U.S. law, but sometimes the companies are able to add additional patents that extend their exclusivity. Merck's patents on the subcutaneous version of Keytruda could protect that formulation until at least 2040, according to Tahir Amin, co-founder of drug patents watchdog group Initiative for Medicines, Access & Knowledge (I-MAK). Northwell's Mulloy said moving patients to subcutaneous versions of drugs also opens up spots in infusion centers for additional patients.
Wealthy investors betting on luxury real estate would do best by putting their money in Dubai or Miami next year, according to a new report. In a ranking 25 of the world's top luxury, or "prime," real estate markets, Dubai topped the list, with prices expected to increase 13.5% in 2023, according to real estate consultancy Knight Frank. The worst performers next year are expected to be Seoul and London, with prices expected to drop 3% for both. Across the 25 cities, Knight Frank expects prices to rise by an average of 2% in 2023, revised down from the 2.7% Knight Frank projected six months ago. Political and economic volatility in many countries will also lead to a flight to safety in real estate, "pushing buyers to mature and transparent luxury markets."
The chip is called the Zynq UltraScale+ MPSoC and was developed by Xilinx, which was acquired by AMD this year. This will allow automakers to update not only software, but also the chip, after the car is sold, Rehan Tahir, AMD’s senior product marketing manager for automotive told Reuters. Tahir said the Aisin auto parking system will start production on 2024 models, but declined to say which car brands would use it. Tahir said the Aisin system works with four cameras and 12 ultrasonic sensors on the car to parallel park and also back into parking spaces. But the human in the car will have to decide if that spot is in a no-parking zone, he said.
Now a wave of startups offer access to a new category of drugs coupled with intensive behavioral coaching online. These patients pay hundreds, if not thousands, of dollars, to access new drugs, called GLP-1 agonists, along with online coaching to encourage healthy habits. (That price includes generic drugs, but not the newer GLP-1 agonists, like Wegovy.) The firms say they’re on the vanguard of weight care, both citing the influence of biology and other scientific factors as key ingredients to their approaches. Found said older generics like zonisamide are more accessible than the GLP-1 agonists advertised on social media and their own website.
N'DJAMENA, Nov 11 (Reuters) - Chad has reached agreement on a plan with creditors, which includes Swiss commodities trader Glencore (GLEN.L), for its $3 billion external debt, which could pave the way for more IMF funding. It is also China's first participation in a finalised joint debt treatment deal with other creditors, a source close to the negotiations told Reuters. A third of the central African country's external debt of nearly $3 billion is commercial and concentrated in an oil-backed loan from Glencore. "We are pleased that all stakeholders have agreed on how Chad's external debt should be treated," a Glencore spokesperson said in an emailed statement. Chad's statement did not specify the terms of the debt relief agreement.
Philippines' death toll from Tropical Storm Nalgae climbs to 72
  + stars: | 2022-10-28 | by ( ) www.reuters.com   time to read: +2 min
[1/3] Flood waters surround a building following a heavy storm in Datu Odin Sinsuat, Maguindanao, Philippines October 28, 2022 in this still image obtained from a social media video. The tropical storm, which has maximum sustained winds of 95 kilometres (59 miles) per hour and gusts of up to 160 kph (99.4 mph), made landfall in the eastern Catanduanes province early on Saturday. On Friday, search and rescue teams pulled bodies from water and thick mud after Nalgae triggered flooding and landslides. "We are now gathering all rescue teams and will conduct a briefing before deployment," Nasrullah Imam, disaster agency official at Maguindanao province, said. An average of 20 tropical storms hit the Philippines annually.
The Inflation Reduction Act is set to lower drug prices for millions of people in the United States — but experts fear pharmaceutical companies could exploit loopholes in the bill, ultimately keeping prescription costs high for many. The tactics may ultimately threaten the law’s ability to lower drug costs for consumers. Higher prices for new drugsOther experts are concerned about how companies might abuse the inflation rebate rule in the health law. The provision, which takes effect next year, imposes a rebate on drug manufacturers that raise the prices of their medications faster than inflation. By releasing new drugs at higher prices, drug companies will be able to make up for any lost revenue that they would normally receive from steadily raising prices each year, she said.
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