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March 3 (Reuters) - The U.S. Food and Drug Administration (FDA) said on Friday there was no indication that contaminated cough and paracetamol syrups that caused deaths of children in Gambia last year have entered the U.S. drug supply chain. This comes after an investigation led by the U.S. Center for Disease Control and Prevention and Gambian scientists reported on Thursday that these medicines contaminated with toxic levels of diethylene and ethylene glycol led to acute kidney injury among 78 children in Gambia. "We will continue to monitor the situation and keep the public and health care professionals updated of any changes in status to the U.S. market," Patrizia Cavazzoni, director for FDA's Center for Drug Evaluation and Research, said in a tweet. In October, the World Health Organization sent out an alert saying four cough syrups containing toxic levels of diethylene and ethylene glycol made by India's Maiden Pharmaceuticals Ltd should be withdrawn. Reporting by Mariam Sunny in Bengaluru; Editing by Maju SamuelOur Standards: The Thomson Reuters Trust Principles.
The links between the children's deaths and contaminated medicines first came to light in October, when the World Health Organization sent out an alert saying four cough syrups made by India's Maiden Pharmaceuticals Ltd contained toxic levels of diethylene and ethylene glycol and should be withdrawn. The new investigation "strongly suggests" that medicines contaminated with the toxins, imported into Gambia, led to the cluster of acute kidney injury among 78 children. Maiden has denied its drugs were at fault for the deaths in Gambia, and the Indian government has said the syrups showed no contamination when it tested them. "This likely poisoning event highlights the potential public health risks posed by the inadequate quality management of pharmaceutical exports," the report said. Since the deaths in Gambia, 201 children have also died in Indonesia, and 19 in Uzbekistan, linked to different manufacturers' contaminated cough syrups.
They say the attributes that have made this virus thrive in wild birds likely make it less infectious to people. Although the exact changes required for a bird flu virus to become easily transmissible in people are not known, a pair of landmark studies done a decade ago offer some clues. Mink have both avian and human-type receptors, but avian receptors are scarce in humans and located deep in the lungs. That change is a must if a bird flu virus is to spread easily in people. None of the experts discounted the possibility that H5N1 or another avian flu virus could mutate and spark a pandemic, and many believe the world has not seen its last flu pandemic.
How Deadly Was China’s Covid Wave?
  + stars: | 2023-02-15 | by ( James Glanz | Mara Hvistendahl | Agnes Chang | ) www.nytimes.com   time to read: +15 min
China’s official count 0 2.5 million 83,150 deaths Model based on Shanghai outbreak 1.6 million deaths LOW ESTIMATE HIGH ESTIMATE Estimate using travel patterns 970,000 deaths Estimate using recent testing data 1.5 million deaths Estimate based on U.S. death rates 1.1 million deaths China’s official count 0 2.5 million 83,150 deaths Model based on Shanghai outbreak 1.6 million deaths LOW EST. But China’s official Covid death toll for the entire pandemic remains strikingly low: 83,150 people as of Feb. 9. Four separate academic teams have converged on broadly similar estimates: China’s Covid wave may have killed between a million and 1.5 million people. Why official data underrepresents China’s outbreak83,150 deaths China’s official count on Feb. 9 0 2.5M 83,150 deaths China’s official count on Feb. 9 0 2.5 millionChina has a narrow definition of what counts as a Covid-19 death. But the work was unwavering in its ultimate conclusion: Ending the “zero Covid” policy was likely to overwhelm the health care system, producing an estimated 1.6 million deaths.
After hours of frantic calls, Steven was taken to a packed hospital and given oxygen and a bed in a children’s ward. If you know the head of the hospital, then there won’t be trouble getting a bed," a Shanghai doctor said. Although China has tried to crack down on doctor bribery, the regulatory focus has been on payments from pharmaceutical companies rather than patients. Doctors and experts said the use of red packets and "guanxi", or connections, to gain access persists. "Many of those rural patients, COVID patients, that had severe symptoms would choose not to proactively seek care; instead they just die at home," Huang said.
HONG KONG, Feb 8 (Reuters) - The world should "calm down" about the possibility of new COVID-19 variants circulating in China, leading Chinese scientist George Gao said. "The world should completely calm down from the fear that there are new variants or special variants circulating (in China)," Gao, professor at the Institute of Microbiology at the Chinese Academy of Sciences and former head of the Chinese Center for Disease Control and Prevention (CDC), told Reuters. The variants causing infections in China were the same Omicron sub-variants - BA.5.2 and BF.7 - seen elsewhere in the world, he said by email. Gao said China was continuing widespread viral genomic sequencing, and would identify any new variants if they emerged. A total of 13 cases of variants were found, including 1 case of XBB.1, 5 cases of BQ.1.1, 1 case of BQ.1.1.17, 4 cases of BQ.1.2 and 2 cases of BQ.1.8.
HONG KONG, Feb 8 (Reuters) - The world should "calm down" about the possibility of new COVID-19 variants circulating in China, leading Chinese scientist George Gao said. "The world should completely calm down from the fear that there are new variants or special variants circulating [in China]," Gao, professor at the Institute of Microbiology at the Chinese Academy of Sciences and former head of the Chinese Center for Disease Control and Prevention (CDC), told Reuters. The variants causing infections in China were the same Omicron sub-variants - BA.5.2 and BF.7 - seen elsewhere in the world, he said by email. Gao said China was continuing widespread viral genomic sequencing, and would identify any new variants if they emerged. The authors said there were some limitations to the study, including China's decision to end large-scale mandatory testing.
Gold ticks up as dollar slips ahead of Fed meeting
  + stars: | 2023-01-30 | by ( ) www.cnbc.com   time to read: +2 min
Pure 1,000-gram gold bars produced by South Korea's LS-Nikko are stacked in a dealers room in Seoul on January 9, 2009. Gold prices inched higher on Monday as the U.S. dollar eased, while market participants globally awaited a slew of central bank meetings with the main focus on the Federal Reserve. Spot gold rose 0.3% to $1,932.84 per ounce, as of 0457 GMT. The European Central Bank (ECB) and the Bank of England (BoE) are also having policy meetings this week. Spot silver gained 0.6% to $23.70 per ounce, platinum rose 0.6% to $1,017.69, and palladium climbed 1.7% to $1,646.41.
China says COVID situation at 'low level' after holiday
  + stars: | 2023-01-30 | by ( ) www.reuters.com   time to read: +2 min
Travel domestically as well as in and out of China during the holiday period rose sharply as millions boarded planes, trains, buses and highways after Beijing abruptly dismantled an almost three-year zero-COVID policy in early December. China's sudden relaxation of COVID restrictions was followed by a wave of infections across its 1.4 billion population. Last week, however, the China Center for Disease Control and Prevention said there was no significant rebound in cases during the holiday, the number of severe COVID cases and deaths had dropped, and no new mutant strains had been identified. The CDC also said last week critically ill COVID cases in China fell 72% from a peak early this month while daily deaths among COVID patients in hospitals dropped 79% from their peak. Reporting by Ethan Wang and Bernard Orr; Editing by Jacqueline WongOur Standards: The Thomson Reuters Trust Principles.
According to official data, the number of COVID deaths a showed weekly decline, however. China abandoned its strict "zero COVID" policy in early December after protests against the restrictions, allowing people to travel and the virus to spread rapidly throughout the country. An estimated 226 million domestic trips were made by all means including flights during the holiday week, state broadcaster CCTV reported, citing government figures. This compares to around 130 million domestic trips during the holiday week last year, according to the transport ministry, but is still far below pre-pandemic levels: In the last Lunar New Year holiday before the novel coronavirus emerged in late 2019, some 420 million trips were made. During the Lunar New Year holiday in 2019, 12.53 million cross-border trips were made, the Xinhua news agency reported.
Jan 27 (Reuters) - Oil prices edged marginally higher on Friday, extending for a second session on strong U.S. economic data and strengthening hope that the reopening of the Chinese economy would boost demand. Improving gross domestic product and inflation data in the United States provided hope that the U.S. Federal Reserve could slow its pace of interest rate hikes, reducing fear of curtailment in economic activity and consequent oil demand. The figures point to the normalisation of China's economy, thereby boosting expectations of a recovery in oil demand. Crude prices were also supported by strong demand for jet fuel and diesel as supplies remain tight. Also, the European Commission is proposing the European Union set a $100 per barrel price cap on premium Russian oil products such as diesel and a $45 per barrel cap on discounted products such as fuel oil, EU officials said on Thursday.
China abruptly ended its strict zero-Covid policy in early December after three years and infections surged across the world’s most populous country. The CDC said the number of critically ill patients in China peaked on Jan. 4 at 128,000 cases and fell to 36,000 cases by Jan. 23. The number of deaths in hospitals, meanwhile, reached a daily peak of 4,273 on Jan. 4 and fell to 896 by Jan. 23. Visits to fever clinics fell 96.2%, from a peak of 2.867 million on Dec. 22 to 110,000 on Jan. 23. On Jan. 12, authorities announced that nearly 60,000 people with Covid had died in hospitals since China dismantled its strict zero-Covid policy.
Soaring input costs and a bird flu outbreak have driven up US egg prices to multi-year highs. Farmers across the US have pinpointed two factors that are fuelling the egg price crisis. Spiraling inflation has squeezed their input costs higher – and they've had to respond by raising egg prices. That's because the US is also contending with a vicious outbreak of bird flu, which is killing hens and reducing overall egg supplies. And with inflation still remaining elevated by historical standards and bird flu fueling a steep drop-off in supply, it's unlikely that the egg price crisis will be over anytime soon.
China Daily via REUTERSHONG KONG, Jan 25 (Reuters) - Critically ill COVID-19 cases in China are down 72% from a peak early this month while daily deaths among COVID-19 patients in hospitals have dropped 79% from their peak, the Center for Disease Control and Prevention said on Wednesday. The CDC said the number of critically ill patients in China peaked on Jan. 4 at 128,000 cases and fell to 36,000 cases by Jan. 23. The number of deaths in hospitals, meanwhile, reached a daily peak of 4,273 on Jan. 4 and fell to 896 by Jan. 23. Visits to fever clinics fell 96.2%, from a peak of 2.867 million on Dec. 22 to 110,000 on Jan. 23. On Jan. 12, authorities announced that nearly 60,000 people with COVID had died in hospitals since China dismantled its strict zero-COVID policy.
The Lunar New Year is the most important annual holiday in China. A popular temple fair at Badachu Park that was suspended for three years will be back this week, but similar events at Ditan Park and Longtan Lake Park have yet to return. Andy Wong / APIn Hong Kong, revelers flocked to the city’s largest Taoist temple, Wong Tai Sin Temple, to burn the first incense sticks of the year. Worshippers believe those who are among the first to place their incense sticks will stand the best chance of having their prayers answered. As communities across Asia welcomed the Year of the Rabbit, the Vietnamese were celebrating the Year of the Cat instead.
One Beijing resident said she wished the year of the rabbit will bring "health to everyone". "I think this wave of the pandemic is gone," said the 57-year-old, who only gave her last name, Fang. Chinese health experts say the wave of infections across the country has already peaked. The death count reported by Chinese authorities excludes those who died at home, and some doctors have said they are discouraged from putting COVID on death certificates. The possibility of a big COVID rebound in China over the next two or three months is remote as 80% of people have been infected, Wu said.
China says Covid outbreak has infected 80% of population
  + stars: | 2023-01-21 | by ( ) www.cnbc.com   time to read: +1 min
The possibility of a big Covid-19 rebound in China over the next two or three months is remote as 80% of people have been infected, a prominent government scientist said on Saturday. Hundreds of millions of Chinese are traveling across the country for holiday reunions that had been suspended under recently eased Covid curbs, raising fears of fresh outbreaks in rural areas less equipped to manage large outbreaks. China has passed the peak of Covid patients in fever clinics, emergency rooms and with critical conditions, a National Health Commission official said on Thursday. Nearly 60,000 people with Covid had died in hospital as of Jan. 12, roughly a month after China abruptly dismantled its zero-Covid policy, according to government data. But some experts said that figure probably vastly undercounts the full impact, as it excludes those who die at home, and because many doctors have said they are discouraged from citing Covid as a cause of death.
China says COVID outbreak has infected 80% of population
  + stars: | 2023-01-21 | by ( ) www.reuters.com   time to read: +1 min
BEIJING, Jan 21 (Reuters) - The possibility of a big COVID-19 rebound in China over the next two or three months is remote as 80% of people have been infected, a prominent government scientist said on Saturday. Hundreds of millions of Chinese are travelling across the country for holiday reunions that had been suspended under recently eased COVID curbs, raising fears of fresh outbreaks in rural areas less equipped to manage large outbreaks. China has passed the peak of COVID patients in fever clinics, emergency rooms and with critical conditions, a National Health Commission official said on Thursday. Nearly 60,000 people with COVID had died in hospital as of Jan. 12, roughly a month after China abruptly dismantled its zero-COVID policy, according to government data. Reporting by Beijing newsroom; Editing by Raju Gopalakrishnan and William MallardOur Standards: The Thomson Reuters Trust Principles.
[1/3] A medical worker helps a patient receiving treatment at the emergency department of a hospital, amid the coronavirus disease (COVID-19) outbreak in Shanghai, China January 17, 2023. Travellers bustled through railway stations and subways in Beijing and Shanghai, many ferrying large wheeled suitcases and boxes stuffed with food and gifts. The infection rate in the southern city of Guangzhou, capital of China's most populous province, has now passed 85%, local health officials announced on Wednesday. Clinics in rural villages and towns are now being fitted with oxygenators, and medical vehicles have also been deployed to isolated areas. Doctors in both public and private hospitals were being actively discouraged from attributing deaths to COVID, Reuters reported on Tuesday.
According to official statistics, there were about five medical personnel and fewer than five hospital beds per 1,000 people in China’s rural areas in 2020, compared with more than 11 medical personnel and almost nine hospital beds in urban areas. Jiao Yahui, an official at the National Health Commission, said the government’s Covid strategy for rural areas had two main focuses. The lack of facilities means those with Covid are more likely to travel elsewhere for treatment or simply recover at home to avoid further exposure in hospitals. A local resident with the last name Li said he had attended five funerals since last December, all for people who died after contracting Covid. He said he had heard that at least 300 older people died this winter in the county, not including its administered villages or towns.
If doctors believe that the death was caused solely by COVID-19 pneumonia, they must report to their superiors, who will arrange for two levels of "expert consultations" before a COVID death is confirmed, it said. "We have stopped classifying COVID deaths since the reopening in December," said a doctor at a large public hospital in Shanghai. Three other doctors at public hospitals in different cities said they were unaware of any such guidance. Before Saturday, China was reporting five or fewer COVID deaths per day. But the hospital told him it had run out of medicine, so they could only go home.
Air travel recovers in China amid COVID infection worries
  + stars: | 2023-01-14 | by ( ) www.reuters.com   time to read: +5 min
The industry needs to "fully understand the special nature, and complexity of the Spring Festival migration in 2023", Song said in a statement on Friday. It expects a Spring Festival boom in tourism. Cinema box office receipts are on track to generate revenue of as much as 10 billion yuan ($1.5 billion) during the Spring Festival period, a brokerage has forecast. According to Guosen Securities, box office revenues in 2022 totalled less than 30 billion yuan, down 36% from a year earlier. ($1=6.7010 Chinese yuan renminbi)Reporting by Shanghai newsroom; Editing by Tony Munroe and Clarence FernandezOur Standards: The Thomson Reuters Trust Principles.
The UN agency said China was heavily under-reporting deaths from COVID, although it is now providing more information on its outbreak. China's foreign ministry said the country's health officials have held five technical exchanges with the WHO over the past month and have been transparent. Concerns over data transparency were among the factors that prompted more than a dozen countries to demand pre-departure COVID tests from travellers arriving from China. Tensions escalated this week with South Korea and Japan, with China retaliating by suspending short-term visas for their nationals. Still, traffic data and other indicators have not yet fully recovered to levels of just a few months ago.
The holiday, known before the pandemic as the world's largest annual migration of people, comes amid an escalating diplomatic spat over COVID curbs that saw Beijing introduce transit curbs for South Korean and Japanese nationals on Wednesday. The virus is spreading unchecked in China after Beijing abruptly began dismantling its previously tight curbs in early December following historic protests. Among them, South Korea and Japan have also limited flights and require tests on arrival, with passengers showing up as positive being sent to quarantine. COUNTING DEATHSSome of the governments that announced curbs on travellers from China cited concerns over Beijing's data transparency. Annual spending by Chinese tourists abroad reached $250 billion before the pandemic, with South Korea and Japan among the top shopping destinations.
REUTERS/Tingshu WangBEIJING, Jan 11 (Reuters) - Chinese state media defended on Wednesday the retaliatory measures against South Korea and Japan over their COVID-19 travel curbs as "reasonable", while Chinese tourists decried Seoul's "insulting" treatment on social media. South Korea, Japan, the United States and more than a dozen other countries imposed at the start of the year requirements for pre-departure negative test results from visitors from China. 'INSULTING'Chinese social media anger mainly targeted South Korea, whose border measures are the strictest among the countries that announced new rules. Global Times reserved a separate article for South Korea, saying the measures made Chinese people suspicious that Seoul was putting up a "political show." Annual spending by Chinese tourists abroad reached $250 billion before the pandemic, with South Korea and Japan among the top shopping destinations.
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