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In ‘Fatal Attraction,’ Lizzy Caplan Makes a Mess
  + stars: | 2023-04-24 | by ( Alexis Soloski | ) www.nytimes.com   time to read: +1 min
Despite spray tans and brief stints as a blonde, she could rarely convince producers to see her as the heroine, the nice girl. “That’s the journey of every brunette.”The joke came by way of a video call in early April from her home in North London. (She and her husband, the English actor Tom Riley, spend half the year there and the other half in Los Angeles.) Jesse Eisenberg, her co-star in the FX limited series “Fleishman Is in Trouble,” expressed a similar observation. “She has such an unusual, distinctive quality of world weariness and humor, jadedness, but also hopefulness,” he said in a phone interview.
Blackstone raises $30.4 billion for latest real estate fund
  + stars: | 2023-04-11 | by ( ) www.reuters.com   time to read: +1 min
April 11 (Reuters) - Blackstone Inc (BX.N) said on Tuesday it had raised $30.4 billion for its latest global real estate fund, as the private equity behemoth looks to double down on the industry. The fund, called Blackstone Real Estate Partners X, is 48% bigger than the asset management giant's previous real estate fund which closed in 2019. "Sector selection has never been more critical as we witness the bifurcation of performance within real estate," Ken Caplan, global co-head of Blackstone Real Estate, said in a statement. Blackstone shares were up nearly 1% in premarket trading. Reporting by Niket Nishant in Bengaluru; Editing by Shailesh KuberOur Standards: The Thomson Reuters Trust Principles.
An economics professor was stunned by the progress ChatGPT made in an exam in just three months. Bryan Caplan of George Mason University said the chatbot got a D in his economics test in January. Bryan Caplan, an economics professor at George Mason University, told Insider the latest version of ChatGPT could now be responsible for the first big bet he's ever lost. Caplan told Insider the bot failed to understand basic concepts, such as the principle of comparative and absolute advantage. "I'm probably going to lose this AI bet but I am totally on board to do a bunch more end-of-the-world AI bets because I think these people are out of their minds."
So You Want to Turn an Office Building Into a Home? There’s an appealing simplicity to the idea of converting office buildings into housing. Basically, they did this:How to Turn a 26-story Office Building Into a 30-story Apartment Building Cut a hole through 23 floors of the building. How to Turn a 26-story Office Building Into a 30-story Apartment Building Cut a hole through 23 floors of the building. That could change with tax abatements and subsidy programs, or if outdated office buildings lose so much value that the cost of acquiring them plummets.
A newly approved drug intended to slow the progression of Alzheimer’s disease offers patients hope, but it will come with a steep price tag: $26,500 a year. That drug initially cost $56,000 per year before Biogen slashed the price in half, to $28,000 annually. Dr. David Rind, the institute's chief medical officer, said an appropriate cost for the drug is $8,500 to $20,600 a year. John Domeck, 60, of Aurora, Ohio is currently enrolled in a phase 3 clinical trial testing Leqembi. But right now, the clinical trial for Leqembi shows that the drug provides "modest efficacy at a big, big price," Caplan said.
A digital mental health company is drawing ire for using GPT-3 technology without informing users. Koko co-founder Robert Morris told Insider the experiment is "exempt" from informed consent law due to the nature of the test. "The participants should have given informed consent and this should have passed through an IRB [institutional review board]." A women seeks mental health support on her phone. Beatriz Vera/EyeEm/Getty ImagesChatGPT and the mental health gray areaStill, the experiment is raising questions about ethics and the gray areas surrounding the use of AI chatbots in healthcare overall, after already prompting unrest in academia.
The Tom Brady of Other Jobs
  + stars: | 2022-12-24 | by ( Francesca Paris | ) www.nytimes.com   time to read: +17 min
Meet them, and decide for yourself:The Tom Brady of Paramedics Jesse Izaguirre, 70Gardena, Calif.Jesse Izaguirre loves working with younger paramedics. Hopefully never.”The Tom Brady of Bakers Helen Fletcher, 83Clayton, Mo. Chalk it up to a great big fib.”The Tom Brady of Artists Lilian Thomas Burwell, 95Highland Beach, Md. “I should’ve signed them.”The Tom Brady of Biologists Maria Elena Zavala, 72Los AngelesProfessional longevity runs in Maria Elena Zavala’s family. It didn’t vanish when they crossed the border.”The Tom Brady of Loggers Earl Pollock, 82Hamburg, Ark.
Meanwhile, laborers who rely on social-media platforms for visibility, reputation burnishing, and income have been left reeling — from journalists and academics to freelancers and adult performers. Last month, a plus-size creator told me how self-censorship becomes a risk-reduction strategy for marginalized creators. As the journalist Paul Gallant argued, queer content creators face a continuous struggle to avoid "the wrath that comes from violating ever-changing and poorly explained terms of service." Even coverage of the influence on social-media creators has been more tuned in to those with the biggest followings. But the real pain from this tug-of-war for the future of social media will be felt by those who have long faced the greatest hurdles: marginalized creators.
CNN —If you find yourself disliking everyone in Hulu’s too precious “Fleishman is in Trouble,” don’t worry, because it’s not clear they like themselves. Brodesser-Akner writes for the New York Times magazine, which becomes readily apparent in this Manhattan-centered story about the angst-ridden well to do, which approximates what the Times’ Sunday Styles section would look like if it sprouted legs. The initial focus is on newly divorced Toby Fleishman (Eisenberg), whose story is told by his college friend Libby (Caplan), serving as the relentless narrator of everyone’s innermost thoughts. The series periodically flashes back to Toby and Rachel’s younger days, showing how they met and how the relationship soured. “Fleishman is in Trouble” premieres November 17 on Hulu.
There are more than 100,000 people in the United States waiting for an organ transplant, according to the United Network for Organ Sharing, known as UNOS. Only a little more than 50% of people waiting for an organ will receive one within five years, according to UNOS. The industry recognizes the importance of finding alternatives to using organs from deceased human donors to address the national shortage. "Even though we're all fascinated by transplant, the ultimate goal is to get rid of it," Caplan said. Watch the video above to learn more about how the organ transplant system works and what we can do to increase supply while also addressing the inequalities.
Pfizer plans to sell the Covid vaccine it developed with BioNTech at $110 to $130 per dose for teens and adults once the U.S. government stops paying for them, the drugmaker said Friday. Since the start of the pandemic, the government has provided Americans with free Covid tests, vaccines and treatment, through a combination of funding from Congress and other government programs. The government has already stopped providing free Covid tests. A CDC advisory committee voted Wednesday to add Covid vaccines to the Vaccines for Children program, a federal plan that provides free vaccines to children eligible for or covered by Medicaid. Pfizer said it also plans to provide free vaccines to people without insurance through its patient assistance program.
Courtesy of Leilani GrahamIf pig organs turn out to be just as effective as human organs, she added, "That is more appealing to me than using marginal donors." If the technique works for human organs in the future, it could allow clinicians to preserve many more organs for donation after death. Changing organs' blood typeEnzymes are delivered to a lung inside a perfusion machine at Dr. Marcelo Cypel’s lab. Growing synthetic organs from stem cellsResearcher Stormy Chamberlain holds a tray of stem cells at the University of Connecticut's Stem Cell Institute. Hanna started a company called Renewal Bio to pursue the possibility of turning stem cells into organs for transplants.
'The recession has begun' The U.K. is the only G-7 economy not to have re-attained its pre-pandemic GDP level by the second quarter of 2022, Citibank Chief U.K. The ONS said GDP was only just returning to its pre-pandemic level, highlighting the challenge facing Prime Minister Liz Truss' "growth, growth, growth" agenda. "We now believe the recession in the U.K. has begun in the third quarter of 2022 and will likely last for three quarters. "The cost of living crisis is having a detrimental effect on individuals, not only financially, but physically and mentally too." Members of the CWU (Communication Workers Union) also continue to strike, including 115,000 postal employees of former state monopoly Royal Mail.
Courtesy of Leilani GrahamIf pig organs turn out to be just as effective as human organs, she added, "That is more appealing to me than using marginal donors." While much of the shortage is driven by imperfect logistics and bureaucracy rather than supply, cutting-edge research could make organs — human, pig, or synthetic — more accessible in Graham's lifetime. If the technique works for human organs in the future, it could allow clinicians to preserve many more organs for donation after death. Changing organs' blood typeEnzymes are delivered to a lung inside a perfusion machine at Dr. Marcelo Cypel’s lab. Growing synthetic organs from stem cellsResearcher Stormy Chamberlain holds a tray of stem cells at the University of Connecticut's Stem Cell Institute.
The Inflation Reduction Act is set to lower drug prices for millions of people in the United States — but experts fear pharmaceutical companies could exploit loopholes in the bill, ultimately keeping prescription costs high for many. The tactics may ultimately threaten the law’s ability to lower drug costs for consumers. Higher prices for new drugsOther experts are concerned about how companies might abuse the inflation rebate rule in the health law. The provision, which takes effect next year, imposes a rebate on drug manufacturers that raise the prices of their medications faster than inflation. By releasing new drugs at higher prices, drug companies will be able to make up for any lost revenue that they would normally receive from steadily raising prices each year, she said.
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