Jusuf Nurkic recorded 14 points and eight rebounds, and Justise Winslow had 12 points, nine rebounds and nine assists.
Nic Claxton recorded 18 points and nine rebounds while Cam Thomas contributed 17 points and six assists off the bench.
Anthony Edwards led Minnesota with 24 points, while Karl-Anthony Towns had 22 points, 11 rebounds and five assists.
RJ Barrett finished with 22 points and nine rebounds while Cam Reddish added 11 points off the bench.
Kelly Oubre Jr. led the Hornets with 17 points, while James Bouknight had a season-high 14 points.