Blake Rutherford hit an RBI single, Cody Wilson -- who pinch-ran for Arcia -- hit a two-run double and Vargas singled home Wilson.
The Yankees had 15 hits, led by Wilmer Difo (2-for-4, home run), Benjamin Cowles (homer) and Estevan Florial (2-for-4, three RBIs).
Cardinals 16, Marlins 2Masyn Winn went 3-for-4 with four RBIs and Willson Contreras doubled and went 2-for-3 with three RBIs as St. Louis throttled Miami in Sarasota, Fla.
The Cardinals collected 17 hits, with Dylan Carlson contributing two hits, two RBIs and two runs.
The Marlins' Jerar Encarnacion went 2-for-3 with one RBI.