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watch nowDrugmakers are betting that delivering radiation directly to tumors will become the next big cancer breakthrough. That can allow the treatment to deliver radiation to cancer cells and spare the rest of the body from the level of damage that comes with many cancer drugs. For Pluvicto, patients come in once every six weeks for up to six treatments. One opportunity Bristol Myers Squibb sees is combining radiopharmaceuticals with existing cancer drugs like immunotherapy, said Robert Plenge, Bristol's chief research officer. But she thinks the technology will become an important part of cancer drugs in the next decade.
Persons: Eli Lilly, They've, Michael Schmidt, Schmidt, Franco Origlia, Jacob Van Naarden, Eli Lilly's, Lilly, Biopharma, Van Naarden, Radiopharmaceuticals, Bristol Myers, Ben Hickey, RayzeBio, Hickey, Victor Bulto, Bulto, Timothy Korytko, Ronald Coy, Sharon, Ronald Coy Ronald Coy, Coy, who's, Coy hasn't, she's, we've, Eli Lilly's Van Naarden, Bristol Myers Squibb, Robert Plenge, Susan Galbraith, Galbraith Organizations: Bristol Myers Squibb, AstraZeneca, Guggenheim Securities, Novartis, NSA, Pharmaceutical, Bassett Healthcare Network, Bristol, Fusion Pharmaceuticals, Guggenheim Locations: Aedea Rome, Italy, radiopharmaceuticals, Swiss, FactSet, Bristol, Indiana, U.S, New York, Bassett
Rather than building an entirely new vessel, it was decided to modify medium-sized landing ships (classified as LSMs for 'Landing Ship Medium'). Officially renamed USS White River in 1955, the ship was decommissioned again in 1956. A day after that, White River fired on a nearby VC anti-aircraft site, destroying it and killing or wounding 11 guerillas. Winstead/National ArchivesFuture shore bombardment and LSMsDespite its value and firepower, by 1970, White River was showing its age. Now known as the Medium Landing Ship program, the Navy hopes to acquire 18 to 35 of the vessels.
Persons: , White, Cmdr, Roy E, McCoy, Chris Page, we'd, R.E, Winstead, USS Zumwalt, hasn't, they're, Benjamin Brimelow Organizations: Service, US Defense Department, Business, Navy, US Navy, USS, National Archives ', Archives, Atlantic Reserve Fleet, Pacific Fleet, Pacific Reserve Fleet, South Vietnamese Army, Archives Future, Naval, AGS, Marine Corps, Operations, Corps, Global Affairs, Fletcher School of Law, Diplomacy, Modern, Institute Locations: Ukraine, White, beachheads, Pacific, Africa, Europe, Plaines, California, Japan, LSMR, Ch'o, Korean, San Diego, Vietnam, South, Ngãi Province, South Vietnam, Cambodian, Gulf, Thailand, Delta, Viet, Quảng Ngãi, Phuoc Tuy Province, Missouri, West
Six years later, sports betting has exploded across the United States, as 38 states have legalized it. The bill addresses three key areas tied to sports betting: advertising, affordability and artificial intelligence. It would mandate gambling operators ensure customers who wager more than $1,000 can afford to do so. "The gambling industry is following a playbook developed by the tobacco industry and this is a direct threat to public health," said Richard Daynard, a law professor and president of the Public Health Advocacy Group at Northwestern. The sports betting operators, meanwhile, are fighting back and saying the industry has brought benefits.
Persons: Sen, Richard Blumenthal, Paul Tonko, Conn, Tonko, It's, Gordon Douglas, he's, Andrew Douglas, Douglas, Blumenthal, Richard Daynard, Chris Cylke, Clyke, Dina Titus, — CNBC's Contessa Brewer Organizations: U.S, Capitol, Sports, American Gaming Association, National Institutes of Health, National Council, Public Health, Northwestern, American Gaming Association's Locations: Washington ,, United States, U.S
Every weekday, the CNBC Investing Club with Jim Cramer releases the Homestretch — an actionable afternoon update, just in time for the last hour of trading on Wall Street. Jim Cramer said earlier Friday that Nvidia received a do-over from Wall Street . As a subscriber to the CNBC Investing Club with Jim Cramer, you will receive a trade alert before Jim makes a trade. THE ABOVE INVESTING CLUB INFORMATION IS SUBJECT TO OUR TERMS AND CONDITIONS AND PRIVACY POLICY , TOGETHER WITH OUR DISCLAIMER . NO FIDUCIARY OBLIGATION OR DUTY EXISTS, OR IS CREATED, BY VIRTUE OF YOUR RECEIPT OF ANY INFORMATION PROVIDED IN CONNECTION WITH THE INVESTING CLUB.
Persons: Jim Cramer, Nvidia, Financials, Love, Lilly, Eli Lilly, Lilly's, haven't, that's, Jim Cramer's, Jim Organizations: CNBC, Tech, Nvidia, Broadcom, Wall, Federal, Energy, Citi, and Drug Administration, Fed, Market, Jim Cramer's Charitable Locations: Ireland, Kisunla, U.S, Europe
Big Lots filed for Chapter 11 bankruptcy this week and is planning hundreds of store closures. I visited a Big Lots store in Maryland to see what it's like to shop there. Go to newsletter preferences Thanks for signing up! It's also planning to shutter 295 of its roughly 1,400 stores, according to a filing in Delaware's bankruptcy court. Private equity firm Nexus Capital Management plans to acquire Big Lots for an undisclosed amount after it emerges from bankruptcy, the retailer said on Monday.
Persons: , It's Organizations: Nexus Capital Management, Service, Business Locations: Maryland
Unfortunately, she was kicked out before she could fulfill her world cruise aspirations. "They didn't just complain, they outright threatened with media unless they get what they want," Mikael Petterson, the founder and CEO of Villa Vie, told BI in an email. "That's how much I had wanted a world cruise." But she was kicked off before Villa Vie Odyssey could set sailOther buyers have begun moving onto the residential cruise ship. So far, Villa Vie has repaid her almost $8,000, with another about $7,400 still pending — still a few thousand short of her $18,600.
Persons: , Jenny Phenix, — Phenix, Bonny Kelter, Mikael Petterson, Vie, Kelter, Villa Vie, Bonny, Petterson, Phenix, Villa, she's, aren't, Fred Olsen Cruise, Fred Olsen's, Angela, Stephen Theriac, Kathy Villalba, Stephen Theriac Petterson, hasn't Organizations: Service, Business, Residences, Sea Cruises, Villa Vie, Villa, Fred Olsen Cruise Lines, Norwegian Cruise, Security Locations: Europe, Asia, Australia, South, North America, Africa, Palm Beach , Florida, Braemar, Norwegian, Florida
CNN —A drug currently used to treat HIV has also been found to dramatically reduce the risk of infection, significantly more than the primary option available for pre-exposure prophylaxis or PrEP. In a Phase 3 clinical trial, 99.9% of participants who took a twice-a-year injection of lenacapavir for HIV prevention did not acquire an infection, according to data from drugmaker Gilead Sciences. There were only two cases among 2,180 patients – effectively reducing the risk of HIV infection by 96% and proving 89% more effective than Truvada, a pill taken once a day. It’s a “significant breakthrough in HIV prevention,” according to a news release from the World Health Organization in July. Gilead said it will use these trial data to start the drug approval process in multiple countries by the end of the year.
Persons: lenacapavir, , Onyema Ogbuagu, Dr, Sanjay Gupta, It’s, Gilead Organizations: CNN, Gilead Sciences, Yale, Research, CNN Health, World Health Organization Locations: Gilead, Argentina, Brazil, Mexico, Peru, South Africa, Thailand, United States, Africa
Gilead 's twice-yearly shot reduced HIV infections by 96% in a second large study, the company said Thursday. The positive phase three trial data on lenacapavir sets the stage for likely approval by the U.S. Food and Drug Administration for HIV prevention. The company said 99.9% of participants who received lenacapavir did not acquire HIV, with two cases among 2,180 people. Gilead in June also said lenacapavir was 100% effective at preventing HIV in another late-stage trial with cisgender women. The trial results should lead to an FDA approval and launch in the market by 2025, Yee said.
Persons: Gilead, Daniel O'Day, lenacapavir, Michael Yee, Yee Organizations: U.S . Food, Drug Administration, PrEP, Centers for Disease Control, Jefferies, CNBC, YouTube Locations: Gilead
CNN —General Mills will sell its North American yogurt business to French dairy firms Groupe Lactalis and Sodiaal in a $2.1 billion deal, the Cheerios maker said on Thursday. Reuters reported in April that General Mills was working with investment bank JPMorgan Chase to attract interest from potential buyers for the business, which houses brands such as Yoplait and Liberté. The North American yogurt business contributed about $1.5 billion to General Mills’ fiscal 2024 net sales. Bloomberg News earlier on Thursday reported that General Mills was in talks to sell the North America yogurt operations to Groupe Lactalis and Sodiaal. In 2021, General Mills sold the European operations of Yoplait to Sodiaal.
Persons: Mills, Lactalis, Sodiaal, Jeff Harmening, Yoplait, General Mills Organizations: CNN, Groupe Lactalis, Canadian, Reuters, JPMorgan Chase, Bloomberg, General, PAI Partners Locations: U.S, Valley , Minnesota, North America, Yoplait, Sodiaal
The bank raised its price target on MercadoLibre Thursday to $2,500 from $2,225, suggesting 22% upside from Wednesday's close. The bank increased its price target to $230 from $200, implying nearly 16% upside from Wednesday's close. Supino also lifted the firm's price target to $93 a share, reflecting about 33% upside from Wednesday's close. Analyst Adam Berlin lowered his 12-month price target to $29 from $34, implying 6% downside. The investment firm's price target of $159 implies more than 2% downside from Wednesday's close.
Persons: Robert Ford Aguilar, — Michelle Fox, Wells, Wells Fargo, Eric Luebchow, Luebchow, Lisa Kailai Han, Sean Conlon, Wolfe, Peter Supino, Supino, Samantha Subin, BofA, George Staphos, a.m, Adam Berlin, Berlin, IPG, — Sean Conlon, Bernstein, Mark Moerdler, — Lisa Kailai Han, Stifel, Simon Yarmak, Andrea Pistacchi, Brandt Montour, it's, Montour, Fred Imbert Organizations: CNBC, Barclays, Bank of America, Diageo, Mercado, Mobile, Sprint, Wolfe Research, UBS downgrades, UBS, billings, GM, Pfizer, Oracle, Simon Property, Property Group, SPG, U.S, New York Stock Exchange Locations: Brazil, Mercado Pago, Wells Fargo, Wells, Roku, Berlin, America, U.S
I'm the managing director and head of the Merrill Center for Family Wealth. But often, they aren't sure what success means to those people, perhaps because family members feel uncomfortable talking about it. How can I build my own personal identity, both within and outside the family wealth? Many rising generation members are concerned about how to carve out a path for themselves. When rising generation members interact with friends and colleagues, it can lead to uncomfortable questions about wealth and privilege.
Persons: , Valerie Galinskaya, we've, I've, We've Organizations: Service, Bank of America, Business, Merrill Center, Family Wealth Locations: New York City, San Francisco
CNBC's Jim Cramer on Wednesday told investors that GameStop increasingly feels like a special purpose acquisition company as the videogame retailer's primary business struggles, but it still manages to raise cash. "Doesn't have to be a full plan, could be the mere idea of a plan, but so far, GameStop doesn't even have that — or if they do, they sure haven't shared it with us." The company managed to turn a profit due to interest on the $4.2 billion it has in cash, not underlying business. He agreed with an analyst from Wedbush who suggested the company close its physical stores and operate as a bank. "Ultimately, GameStop's always vulnerable to a short squeeze because, based on whatever nonsense the memesters can temporarily cook up," Cramer said.
Persons: CNBC's Jim Cramer, haven't, Wednesday's, Cramer, it's, Wedbush, he's, GameStop's Organizations: Wednesday, GameStop
This has spiked the interest rates small business owners are paying on new mortgages, credit, and loans. Related storiesPowell said that small business owners are poised to benefit regardless of the size of the cut and should remain hopeful about future growth. According to the National Federation of Independent Businesses, small business confidence dipped in August. AdvertisementHe said small businesses tend to be more credit-constrained, so changes in interest rates are particularly influential for business owners' management decisions. Are you a small business owner who has experienced a recent change in sales or hiring?
Persons: , Phil Powell, it's, Powell, Jerome Powell, Sean Higgins, Higgins Organizations: Service, Federal Reserve, Business, Indiana Business Research Center, Indiana University Kelley School of Business, Federal Open Markets, Treasury Department, National Federation of Independent Businesses, Kellogg School of Management, Northwestern University
Read previewLeo Kryss sold Jeff Bezos a $79 million Miami mansion. Kryss, the cofounder of Brazilian toy company Tectoy, had listed his seven-bedroom mansion on Indian Creek Island, Miami, for $85 million in May 2023, Business Insider previously reported. After Kryss sold his mansion for $79 million — $6 million below its list price — he learned that the buyer was, in fact, connected to Bezos. Kryss is suing Douglas Elliman, which received a commission of over $3 million for handling the property sale. Bezos owns three properties on the island, with the latest purchased in April for $90 million.
Persons: , Leo Kryss, Jeff Bezos, Kryss, Bezos, Jay Parker, Douglas Elliman, Douglas Elliman's Parker, Benny Klepach, Celine, Celine Klepach, Danny Hertzberg, Tom Brady, Jared Kushner Organizations: Service, Wall, Business, Wall Street Journal, Miami, Elliman, Coldwell Banker, Zillow, BI Locations: Miami, Florida, Dade County, Indian, Biscayne
A 7-Eleven convenience store, operated by Seven & i Holdings Co., in Kawasaki, Japan, on Monday, Aug. 19, 2024. The FTC was concerned that the companies' defense attorneys were advising them to get rid of documents linked to the potential merger ahead of antitrust investigations, Reuters reported. In June, the FTC and the Justice Department launched antitrust investigations into Microsoft, OpenAI and Nvidia. Other recent antitrust investigations include cases against Amazon and Google. Seven & i revealed that Couche-Tard had offered to acquire all outstanding shares of Seven & i for $14.86 per share.
Persons: Canada's Alimentation, Tard, Tokutaka Ito, O Shearman, Ito, — CNBC's Lim Hui Jie Organizations: Seven, Holdings Co, Holdings, U.S . Federal Trade Commission, Reuters, FTC, Justice Department, Microsoft, Nvidia, Amazon, Google, CNBC Locations: Kawasaki, Japan, Asia, .
CNN —A Russian cargo ship suspected of carrying Iranian ballistic missiles for Moscow’s war against Ukraine was seen at a Russian port on the Caspian Sea a week ago, satellite imagery shared with CNN shows. The ship had previously been in the Iranian port of Amirabad on August 29, according to ship tracking data. Period.”The Ukrainian Foreign Ministry summoned the Iranian charge d’affaires, Shahriar Amouzegar, this week following the reports of ballistic missiles being sent to Russia. By September 6, it had left the Russian port for another voyage. Ukrainian President Volodymyr Zelensky has frequently appealed to Kyiv’s allies for greater latitude in using Western missiles against targets inside Russia.
Persons: , , Antony Blinken, Seyed Abbas Araghchi, Shahriar, Amouzegar, Blinken, Sergei Shoigu, Ababil, ” Blinken, Volodymyr Zelensky, Joe Biden, Keir Starmer, Victoria Butenko, Natasha Bertrand, Kylie Atwood Organizations: CNN, Maxar Technologies, US Treasury, Russian Ministry of Defense, Treasury, Russia, Iranian Fatah, Islamic, Ukrainian Foreign Ministry, Washington, Iran, US, Russian Defense, Islamic Revolutionary Guard Corps, Western, UK Locations: Russian, Ukraine, Olya, Port Olya, Astrakhan ., Amirabad, Iran, Russia, London, Iranian, Islamic Republic, France, Germany, Washington, Astrakhan, The, United States
SINGAPORE — Global markets are severely overplaying an oil supply glut, said Jeff Currie, chief strategy officer of energy pathways at private equity giant Carlyle. China's crude oil imports in 2023 had notched a record high. China's oil demand has been declining on the back of a slump in industrial inputs, according the International Energy Agency. On the supply side, black oil production in the U.S., one of the world's top crude oil producers, has been "flat" this year, Currie said. Black oils include crude oil, fuel oil, furnace oil, asphalt and tar.
Persons: Currie, Jeff Currie, Carlyle, I've, Energean Organizations: Asia Pacific Petroleum Conference, SINGAPORE —, International Energy Agency, Reuters Locations: Stanton , Texas, Singapore, SINGAPORE, APPEC, U.S, Egypt, Italy, Croatia
In 1970 there had been only 18,333 students enrolled at degree-granting for-profit schools, less than a quarter of a percent of the total number of college students. In 2010, Tom Harkin, chair of the Senate's education committee, began a two-year investigation into for-profit schools. But even more shocking, federal money flowing to for-profit schools accounted for 25% of all federal student aid and 47% of eventual loan defaults. Students' money enriched every corner of the for-profit industry except one: quality of instruction. In fact, these for-profit students were actually worse off than if they hadn't gone to school at all.
Persons: Kaplan, bankrolling, , underperformers, Ashford, Warburg Pincus, Tom Harkin, Harkin, Goldman Sachs, Goldman, Pell Grant, Ryann Liebenthal Harper, Stephanie Riegg Cellini, Cellini, Ryann Liebenthal Organizations: University of, Apollo Group, ITT Tech, Fortune, Federal Family Education, Ashford, University, company's, Ashford University, Bridgepoint Education, New, Defense Department, Bloomberg, Camp Lejeune, Ryann Liebenthal Harper Collins Publishers, Books, HarperCollins Publishers Locations: California, New York City, Bridgepoint, Pell, Vietnam, Iraq, Camp, Oakland , California
Cate Blanchett touched down in Toronto for a wide-ranging talk about creative conflict on film sets, making big-budget films “risky,” and why her six-time Oscar-nominated film “Carol” struggled to find funding. “We want the numbers,” Blanchett said (though she didn’t specifically name-drop “Disclaimer” maker Apple, which, like most streamers, tends to shield its audience metrics). “At one point, another director was going to do it, and he got sort of taken off the project,” Blanchett said. That prompted her to step away as well, until Haynes expressed interest in the project and got Blanchett back on board. … Anything that gives you the time to think long thoughts and think uncomfortable thoughts, because being an actor, it’s pretty uncomfortable a lot of the time.
Persons: Cate Blanchett, Oscar, Carol ”, Blanchett, Alfonso Cuarón’s, Guy Maddin’s, , ” Blanchett, didn’t, , Todd Haynes, I’ve, Carol, Rooney Mara, Haynes, “ Carol, , Barbie ’, “ Indiana Jones, “ Thor, it’s, you’re Organizations: Alfonso Cuarón’s Apple, Royal Alexandra Theatre, Apple, , NBC Locations: Toronto, Kingdom
The DOJ and the states are seeking a breakup of Google's adtech business. Separately, they said that while a separation of Google's ad server and its ad exchange would be good for competition in the adtech market, it might drive ad server costs up for publishers. Google's ad server is "a loss leader, they make all their money in AdX," the exec said, referring to Google's ad exchange that connects buyers and sellers. Global regulators have Google in their sights, tooAny unraveling of Google's ad empire would be complex. Over the pond, the European Union said last year it might look to break up Google's adtech business.
Persons: , Google's, Tim Nollen, isn't gunning, adtech, Macquarie's Nollen, Bietti, Mark Jamison, there's, Arielle Garcia Organizations: Service, Eastern, Business, US Department of Justice, Google, DOJ, Microsoft, Macquarie, Publishers, US Department of, Northeastern University, Public Utility Research Center, Digital Markets, University of Florida, Global, European Union Locations: Virginia, AdX
While it might look like there's a flurry of advertising hiring, industry insiders say the reality is more sobering. AdvertisementLegacy media companies have sharply cut staff in recent years, including sales, and those jobs aren't coming back. Disney has said it plans to automate half its ad sales. "The number of good job opportunities are few and far between because the large media companies are not hiring as quickly. "Ad sales is no longer ad sales," said Gary Stolkin, global CEO of The Talent Business, a global executive search firm specializing in the creative industries.
Persons: , they've, Jean, Paul Colaco, aren't, Dave Morgan, Lisa Valentino, David Lawenda, David Zaslav, David Ellison's, Christopher Vollmer, Simon Francis, Peter Naylor, Brian Lesser, Lesser, WPP's, Roku, Harry Kargman, Kargman, Krishan Bhatia, Gary Stolkin, Stolkin, who's Organizations: Service, Netflix, Business, Disney, Paramount, Warner Bros, NBA, Companies, MediaLink, TV, Media, Flock Associates, Progressive, Mobile, The Talent Locations: Teads, NBCUniversal
The United States has informed allies that it believes Iran has transferred short-range ballistic missiles to Russia for its war in Ukraine, according to two people familiar with the matter. The White House declined to confirm the weapons transfer but reiterated its concern that Iran is deepening its support of Russia. The White House has been warning Iran for months not to transfer ballistic missiles to Russia. The White House has been on edge for months about a possible deal between Iran and Russia. President Joe Biden is set to host British Prime Minister Keir Starmer for talks at the White House on Friday.
Persons: Ali Khamenei, Masoud Pezeshkian, Sean Savett, Ukraine's, Volodymyr Zelenskyy, William Burns, Joe Biden, Keir Starmer, Karine Jean, Pierre Organizations: Government, United, Security, Kremlin, Moscow, United Nations, CIA, Ukraine, Democratic, White, Iranian, British, Street Journal Locations: Tehran, Iran, United States, Russia, Ukraine, Iranian, Russia's Kursk, London, China, North Korea, Western, Korea, Moscow, Russian, White House, U.S
A person in Missouri has been infected with bird flu, the Centers for Disease Control and Prevention said Friday. The adult, who didn't have known contact with poultry or dairy cows, was hospitalized on Aug. 22 and has recovered. At least 196 herds of dairy cows in 14 states have confirmed outbreaks of the H5 influenza virus, according to the CDC. There has been no evidence that H5N1 — the H5 virus spreading in dairy cows — has been spreading from person to person. The Missouri State Public Health Laboratory was sent a sample from the patient, Missouri health officials said in the release.
Persons: William Schaffner, Schaffner Organizations: Centers for Disease Control, Prevention, CDC, Vanderbilt University Medical Center, Missouri State Public Health Laboratory Locations: Missouri, U.S, Nashville , Tennessee
Hong Kong CNN —The operator of 7-Eleven has rejected an opening offer from the owner of convenience store rival Circle K, indicating the bid was too low and that its global business was worth more. In a statement Friday, Tokyo-based Seven & I Holdings, which owns 7-Eleven, said it was “open” to “sincerely consider” any proposal that is in the best interests of its shareholders. The Financial Times reported on Thursday that Seven & I was open to the possibility of a higher offer from its suitor. Shares in Seven & I have rallied since the news of the offer broke last month, pushing its market value above $38 billion. Although 7-Eleven traces its origins to Dallas, Texas, it was the late Japanese entrepreneur Masatoshi Ito who is credited with turning it into a ubiquitous global brand.
Persons: , Alimentation, Masatoshi Ito, Ito Organizations: Hong Kong CNN, Holdings, Reuters, The Financial Times, Analysts, Speedway, Marathon Petroleum Locations: Hong Kong, Tokyo, Japan, North America, Europe, United States, Dallas , Texas
Instead of high-net-worth individuals, C-suite executives in China are increasingly using business jets, said Paul Desgrosseilliers, general manager at ExecuJet Haite General Aviation Services. ExecuJet HaiteBEIJING — China's wealthy are increasingly looking for ways to move capital outside the mainland to pursue business opportunities, rather than just chasing investment returns, according to asset managers and consultants. The company's active overseas clients rose by nearly 63% year on year to 3,244. Overseas assets under management rose nearly 15% to $5.4 billion from a year earlier, while mainland China assets under management fell over 6% to $15.8 billion, according to Noah's quarterly earnings report. "What we are hearing from them is that the fastest growth in terms of interest from Chinese clients [occurred] in the post-Covid [period to] early last year."
Persons: Paul Desgrosseilliers, ExecuJet, there's, Ryota Kadogaki, Grant Pan, Noah Holdings, Noah, Kadogaki, Mu Chen, That's, Pan, ExecuJet Haite Organizations: General Aviation Services, Beijing Daxing, Monolith, Investors, Ministry of Commerce, CNBC, Noah Holdings, Beijing Daxing International Locations: China, Beijing, BEIJING, Japan, Mainland China, Singapore, Hong Kong, Southeast Asia, East, Africa, Asia Pacific
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