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☆ Investors see a biotech comeback in 2024 as rates fall, deal-making picks up. Stocks to watch
▼ + stars: | 2023-12-28 | by ( Christina Cheddar Berk | In | ) www.cnbc.com time to read: +8 min

Many biotech stocks struggled in 2023 despite a robust year for U.S. drug approvals. "We expect this environment to continue but look forward to the prospect of lower interest rates in 2024." When that happens, Canaccord Genuity said to expect a "strong rally across the biotech sector rewarding innovative, but riskier assets." Analysts have said the rich price reflects the opportunity for ImmunoGen's Elahere cancer treatment , which has quickly established itself as the standard of care for types of ovarian cancer. 'Oversold and cheap' In a research note Friday, Jefferies analyst Michael Yee said "a significant short squeeze" was helping biotech stocks in the fourth quarter.

Persons: Dan Lyons, Janus Henderson, John Newman, Canaccord Genuity, Janus, Lyons, Bristol Myers Squibb, Karuna, AstraZeneca, Eli Lilly, AbbVie, Jonathan Miller, Miller, bode, Jonathan Krinsky, Krinsky, BTIG's, Jefferies, Michael Yee, Yee, NASH, Madrigal, we're, David Risinger, — CNBC's Michael Bloom Organizations: Drug, Federal, Bristol Myers, Karuna Therapeutics, CART, Bristol Myers Squibb, Cerevel Therapeutics, Securities and Exchange Commission, pharma, P Biotech, Nasdaq Biotech, Apogee Therapeutics, Madrigal Pharmaceuticals, Madrigal, resmetirom, Vertex Pharmaceuticals, Leerink Partners Locations: ImmunoGen

☆ I kicked my son out during the peak of his drug addiction. He recovered, and I'm grateful for the years I didn't think I'd get with him.
▼ + stars: | 2023-12-27 | by ( Jennifer Cannon | ) www.businessinsider.com time to read: +5 min

My son started smoking marijuana in high school and things quickly escalated to heroin. download the app Email address Sign up By clicking “Sign Up”, you accept our Terms of Service and Privacy Policy . The 10-year detour his life took after high school spanned all things concerning whether he would make it out of this alive. Standing at the kitchen sink one summer morning in 2010, the warm prickle of hives took shape down my legs. AdvertisementWhen I first learned Bryant was smoking marijuana, I thought, "he's in high school."

Persons: I'm, what's, —, Bryant, I'd, Cesar Deleon, I've, Weeks Organizations: Service, University of North, Engineers, Anonymous, FAU, Tau Beta Pi Locations: Florida, California, University of North Florida, Lake Worth

☆ Healthcare companies are promising to help patients quit Wegovy. There's just one problem with that.
▼ + stars: | 2023-12-19 | by ( ) www.businessinsider.com time to read: +11 min

Inkinen said Virta can help patients quit GLP-1 drugs and keep weight off by adjusting the foods they eat to help them feel full, similar to how the drugs reduce feelings of hunger. About 82% of patients taking Wegovy experience gastrointestinal issues like nausea and diarrhea. WeightWatchers didn't provide Business Insider with published data to support its claims that it can help people keep weight off after quitting weight-loss drugs. AdvertisementHe also advises the weight-loss startup Calibrate, which tapers some patients off GLP-1 drugs after they reach a certain body-mass index. GLP-1 drugs also slash the risk of heart attacks, strokes, and cardiac-related death.

Persons: —, Michael Albert, aren't, Sami Inkinen, Inkinen, Virta, Michael Siluk, Noom's, Linda Anegawa, Carolina Rudah, tirzepatide, Mounjaro, Zepbound —, Eli Lilly, Ozempic, Wegovy, Randy Seeley, Seeley, Robyn Phelps, it's, Robert Kushner, Kushner, Florian Gaertner, It's, Albert, Lisa, she's, I'm Organizations: Service, Business, FDA, Virta, Getty, Nordisk, Michigan Nutrition Obesity Research, University of Michigan, Novo Nordisk, Northwestern University Locations: Denver, Michigan

File photo: A person holds a photo of late Haitian President Jovenel Moise, who was shot dead earlier this month, during his funeral at his family home in Cap-Haitien, Haiti, July 23, 2021. Vincent was arrested days after the attack alongside another Haitian-American, James Solages. At these meetings, the filing said, Vincent often wore a U.S. State Department pin leading people to believe he was employed by the U.S. government. Jaar and Rivera were both sentenced to life in prison, while John is expected to be sentenced on Dec. 19. Reporting by Sarah Morland and Kylie Madry; Editing by Bill BerkrotOur Standards: The Thomson Reuters Trust Principles.

Persons: Jovenel Moise, Ricardo Arduengo, Joseph Vincent, Vincent, Jovenel Moise's, Prince, James Solages, Solages, Christian Sanon's, Moise, Vincent's, Joseph Joel John, German Rivera, Rodolphe Jaar, Jaar, Rivera, John, Sarah Morland, Kylie Madry, Bill Berkrot Organizations: REUTERS, U.S . Drug Enforcement Administration, U.S . State Department, U.S ., Thomson Locations: Cap, Haitien, Haiti, U.S, American, Colombian, Florida, Haitian, Chilean

☆ Why Pfizer's latest stumble in the obesity market is a boon for Eli Lilly
▼ + stars: | 2023-12-01 | by ( Kevin Stankiewicz | In Kevinstankiewicz | ) www.cnbc.com time to read: +5 min

In June, the New York-based pharmaceutical giant stopped developing a different obesity pill, known as lotiglipron , due to concerns about liver safety. Meanwhile, Eli Lilly shares were mainly flat in afternoon trading, at around $591apiece. We lifted our Eli Lilly price target Friday to $630 per share, up from $600. Eli Lilly and Danish rival Novo Nordisk (NVO) are the two dominant players in the obesity market. The longer it takes for competitors to get to this burgeoning market, the more revenue first-movers Eli Lilly and Novo Nordisk can capture.

Persons: Eli Lilly, Jim Cramer, Lilly's, Novo's, Jim, Eli Lilly —, —, Eli, that's, — Novo's, Novo, semaglutide, Jim Cramer's, AJ Mast Organizations: Pfizer, Club, Novo Nordisk, Pharmaceutical, Amgen, AstraZeneca, Bank of America, U.S . National Library of Medicine, U.S . Food, Drug Administration, CNBC, Bloomberg, Getty Locations: New York, Danish, Lilly, U.S, Indianapolis , Indiana

☆ Competition will make obesity drugs successful
▼ + stars: | 2023-12-01 | by ( Robert Cyran | ) www.reuters.com time to read: +3 min

In an interview with the Financial Times, he proposed spreading reimbursements over time if the medication proves to be successful. There’s some practical grounding in that solution, but the path of other similar drugs suggests that a competitive market is a better way to make it successful. Snag is, the drugs cost several thousand dollars per patient annually, even after discounts. Medicare, which covers 66 million seniors, can’t pay for weight loss drugs under current law. While it makes more sense for insurers or governments to pay over time if the drugs benefits last, schemes like the one that Jørgensen suggests can only do so much.

Persons: Lars Fruergaard Jørgensen, Jørgensen, “, Lauren Silva Laughlin, Sharon Lam Organizations: Reuters, Novo Nordisk, Financial Times, Centers for Disease Control, Prevention, North Carolina, The New England, of Medicine, Employers, Thomson Locations: U.S, The, United States, Danish

☆ US obesity docs expect Lilly weight-loss drug to show similar heart benefit as Wegovy
▼ + stars: | 2023-12-01 | by ( Patrick Wingrove | ) www.reuters.com time to read: +5 min

REUTERS/Mike Segar Acquire Licensing RightsDec 1 (Reuters) - Some leading U.S. obesity specialists say they expect Eli Lilly’s (LLY.N) powerful weight-loss drug Zepbound will produce the same or similar heart benefits as Novo Nordisk’s (NOVOb.CO) popular Wegovy as they belong to the same class of medicines. In Novo's pivotal Wegovy trial involving 17,604 overweight and obese people without diabetes, the drug reduced incidence of heart attack, stroke or heart-related death by an impressive 20%. The product, which has the same active ingredient - tirzepatide - as its previously approved diabetes drug Mounjaro, is expected to start shipping it before the end of the year. They said they would readily prescribe Wegovy (semaglutide) if their patients' insurance did not cover Lilly’s drug, or if future trial results do not produce similar heart benefits. Lilly declined to comment on doctors' views that Zepbound might have the same or similar cardiovascular benefits as Wegovy.

Persons: Eli Lilly, Mike Segar, Eli Lilly’s, Lilly, Danish drugmaker, Edmond Wickham, Emily, Zepbound, Tirzepatide, ”, Rohit Kedia, Novo, Chad Weldy, semaglutide, tirzepatide, Farxiga, Boehringer Ingelheim, Lilly’s Jardiance, Patrick Wingrove, Caroline Humer, Bill Berkrot Organizations: Company, REUTERS, Novo, Wegovy, Virginia Commonwealth University . The, Virginia Commonwealth University . The U.S . Food, Drug Administration, Wall Street, Barclays, Providence, Stanford University, Thomson Locations: Branchburg , New Jersey, Danish, Virginia Commonwealth University . The U.S, Zepbound, U.S

☆ GSK CEO says RSV vaccine revenue to top 1 bln pounds in first year
▼ + stars: | 2023-11-30 | by ( Michele Gershberg | ) www.reuters.com time to read: +4 min

GSK had previously forecast 2023 sales for Arexvy between 900 million pounds and 1 billion pounds ($1.26 billion) following a strong U.S. launch. "We’re delighted with the start of our RSV vaccine," Walmsley said in a Reuters Newsmaker interview. The U.S. Food and Drug Administration (FDA) approved Arexvy for adults aged 60 years or older in May and GSK launched the vaccine in the U.S. later in the year. GSK made close to two-thirds of RSV doses given in the United States since early September, according to IQVIA data earlier this month. On Tuesday, rival Pfizer (PFE.N) said it was disappointed in the performance of its RSV shot Abrysvo compared with GSK.

Persons: Walmsley, GSK's, Emma Walmsley, We’re, David Denton, AstraZeneca's, commercialise Johnson, Ludwig Burger, Michael Erman, Josephine Mason, Kirsten Donovan, Elaine Hardcastle Organizations: GSK, Reuters, U.S . Food, Drug Administration, Pfizer, U.S, Thomson Locations: British, U.S, Europe, Japan, United States

☆ Mexico president asks lawmakers to let US military trainers into Mexico
▼ + stars: | 2023-11-29 | by ( ) www.reuters.com time to read: +2 min

[1/3] U.S. President Joe Biden meets with Mexican President Andres Manuel Lopez Obrador on the sidelines of the Asia-Pacific Economic Cooperation (APEC) summit in San Francisco, California, U.S. November 17, 2023. The announcement published Tuesday said President Andres Manuel Lopez Obrador sought permission for 11 U.S. military personnel to take part in a program called "Strengthening the Capacities of the Special Forces of the Defense Ministry." Lopez Obrador has vigorously defended the principle of Mexican sovereignty, passing measures to restrict the ability of U.S. counter-narcotics agents to operate in Mexico. The U.S. troops are expected to arrive in Mexico with their own weapons, ammunition and equipment, the Senate letter added. For his part, Lopez Obrador has been critical of U.S. anti-narcotics officials operating on Mexican territory, accusing U.S. Drug Enforcement Administration (DEA) agents of trampling on Mexican sovereignty.

Persons: Joe Biden, Andres Manuel Lopez Obrador, Kevin Lamarque, Lopez Obrador, Lopez Obrador's, Dave Graham, Drazen Jorgic, Franklin Paul, Deepa Babington Organizations: Economic Cooperation, REUTERS, MEXICO CITY, Mexican Senate, U.S, Special Forces of, Defense Ministry, Special Forces Group, Mexico's Defense Ministry, United States, Drug Enforcement Administration, Thomson Locations: Asia, San Francisco , California, U.S, MEXICO, Mexican, Mexico, United States, Mexico City, Jan, Iraq, Afghanistan

☆ Mexico captures 'El Nini,' Sinaloa Cartel's alleged security boss
▼ + stars: | 2023-11-22 | by ( ) www.reuters.com time to read: +2 min

MEXICO CITY, Nov 22 (Reuters) - The Mexican National Guard on Wednesday captured Nestor Isidro Perez Salas, or "El Nini," who is accused of heading security for the faction of the Sinaloa Cartel headed by the sons of founder Joaquin "El Chapo" Guzman. Seen by U.S. anti-narcotics agents as one of the most ruthless Mexican drug figures, Perez Salas was detained in Culiacan, the Sinaloa Cartel's heartlands, and was taken to Mexico City, according to government detention records. "We're working side-by-side to combat arms trafficking, to tackle organized crime and to address the opioid epidemic, including fentanyl," Biden said. The U.S. and Mexico also agreed with China last week to stem the flow of fentanyl precursor chemicals from the Asian country. In January, Mexican authorities captured Ovidio Guzman in Sinaloa and extradited him to the United States in September.

Persons: Nestor Isidro Perez Salas, Joaquin, El, Guzman, Perez Salas, Ivan Archivaldo Guzman, Joe Biden, Andres Manuel Lopez Obrador, Biden, Ovidio Guzman, Ivan, Manuel Carrillo, Kylie Madry, Sarah Morland, Brendan O'Boyle Organizations: MEXICO CITY, Mexican National Guard, heartlands, U.S . State Department, The State Department, U.S . Drug, Administration, Thomson Locations: MEXICO, Sinaloa, Culiacan, Mexico City, U.S, Mexico, China, United States, Lincoln

☆ Costa Rica makes first-ever fentanyl gang arrests
▼ + stars: | 2023-11-21 | by ( Alvaro Murillo | ) www.reuters.com time to read: +2 min

Four suspects were taken into custody, two Costa Ricans and two Colombians, along with 1,100 fentanyl pills in an operation backed by the U.S. Drug Enforcement Administration that included raids in three towns in central Costa Rica, Security Minister Mario Zamora said at a press conference. The arrests "raises alarms because it confirms the presence of fentanyl" in Costa Rica, said Zamora. As of last month, Costa Rican authorities had been carrying out 10 fentanyl investigations since last year, according to government data. Violent crime in Costa Rica has surged this year with homicides at a record, and the growth blamed on gang turf battles over the country's role as a major transit point for the illicit trade. The fentanyl arrests come as around 70% of Costa Ricans disapprove of President Rodrigo Chaves' crime fighting record, according to a recent poll.

Persons: Mario Zamora, Zamora, Rodrigo Chaves, Alvaro Murillo, David Alire Garcia, Bill Berkrot Organizations: JOSE, Costa Ricans, U.S . Drug Enforcement Administration, Thomson Locations: Costa Rican, United States, Costa Rica, Honduras, Costa Ricans

☆ The 'Ozempic effect' is weighing on gym stocks. But it could turn out to be a boom for the industry
▼ + stars: | 2023-11-16 | by ( Brian Evans | ) www.cnbc.com time to read: +5 min

Will gym stocks be hurt by an "Ozempic effect" similar to the blow that has rocked the medical device and food sector? Stock in Planet Fitness has slipped more than 16% from the start of the year, while Life Time has added roughly 20%. Planet Fitness sunk to a 52-week low in September after the company's board ousted Chris Rondeau as chief executive officer . PLNT YTD mountain Planet Fitness stock. At Life Time, anti-obesity medication is being incorporated into the weight loss programs it offers to members.

Persons: Simeon Siegel, it's, Jefferies, Chris Rondeau, Bahram Akradi, Warren Cheng, PLNT, Cheng, Jeff Zwiefel, Alexander Perry's, Perry, Curtis Harman, Harman, It's, Piper Sandler, Korinne Wolfmeyer, Wolfmeyer Organizations: BMO Capital Markets, ISI, Bank of America, GLP, Wellness, CNBC, Holdings, Nordisk's Ozempic

☆ Italy arrests six in crackdown on fentanyl smuggling from China to U.S.
▼ + stars: | 2023-11-15 | by ( Emilio Parodi | ) www.reuters.com time to read: +3 min

[1/2] An undated handout picture released by Guardia di Finanza shows banknotes that were seized as a part of an operation against fentanyl trafficking from China to U.S., in Piacenza, Italy. Guardia di Finanza Press Office/Handout via REUTERS Acquire Licensing RightsMILAN, Nov 15 (Reuters) - Italian police have arrested six people in a crackdown on a network that allegedly played go-between for fentanyl trafficking from China to the United States, Guardia di Finanza police and prosecutors in the northern city of Piacenza said on Wednesday. Washington is hoping to secure more cooperation from Beijing in combating production of the potent synthetic opioid fentanyl, a scourge in the United States, when President Joe Biden meets Chinese President Xi Jinping on Wednesday. Among those arrested in Italy is the alleged head of the network, a 51-year-old Italian man suspected of buying fentanyl from China over the past three years. He sold it on to buyers in the United States, and in one case in Mexico, the chief prosecutor said.

Persons: Grazia Pradella, Joe Biden, Xi Jinping, Emilio Parodi, Keith Weir Organizations: Guardia, Finanza, REUTERS Acquire, U.S . Drug Enforcement Administration, Reuters, U.S, U.S . Centers for Disease Control, Prevention, Police, Thomson Locations: China, U.S, Piacenza, Italy, United States, Guardia, Washington, Beijing, Mexico, Rome, Ukrainian, Switzerland, Eastern Europe, bitcoin

The two leaders, who will meet on the sidelines of a summit of Asian-Pacific leaders, last spoke a year ago. Both men are seeking to show the world that while the U.S. and China are economic competitors, they are not locked in a winner-take-all faceoff with global implications. Their relationship has been increasingly defined by differences over export controls, Taiwan and the conflicts in the Middle East and Europe. Xi, meanwhile, is looking for assurances from Biden that the U.S. will not support Taiwan independence, start a new cold war or suppress China’s economic growth. “It is reported he’s very worried about the negative opinion of China in the United States,” Schumer said.

Persons: Joe Biden, Xi, Biden, John Kirby, “, We’re, ” Kirby, He's, Chuck Schumer, ” Schumer, Sagar Meghani Organizations: FRANCISCO, U.S, Economic Cooperation, White, Tuesday, National, State Department, APEC, Monetary Fund, Labor Department, Biden, Associated Press Locations: China, U.S, Iran, Taiwan, California, Asia, San Francisco, East, Europe, Tehran, Israel, Washington, Beijing, “, United States

☆ US set to take action to win China's cooperation on fentanyl
▼ + stars: | 2023-11-14 | by ( Michael Martina | ) www.reuters.com time to read: +2 min

Biden will discuss the issue with China's President Xi Jinping on Wednesday in San Francisco at the Asia-Pacific Economic Cooperation (APEC) forum. U.S. National Security Advisor Jake Sullivan said on Tuesday that Washington hoped the summit would result in action to help combat the fentanyl trade. China has long questioned why the U.S. would expect cooperation on fentanyl while targeting the institute. China's embassy in Washington did not immediately respond to a request for comment on the fentanyl issue. Fentanyl is up to 50 times stronger than heroin and is increasingly mixed with other illicit drugs, often with lethal results.

Persons: Jake Sullivan, Karine Jean, Pierre, Leah Millis, Joe Biden's, Bejing, Biden, Xi Jinping, Washington, Marsha Blackburn, Blackburn, Michael Martina, Michelle Nichols, Jonathan Oatis, Bill Berkrot Organizations: National, White House Press, White, REUTERS, FRANCISCO, China's Institute of Forensic Science, U.S . Centers for Disease Control, Prevention, China's, Economic Cooperation, . National, Washington, Institute of Forensic Science, China's Ministry of Public Security, Commerce, Thomson Locations: Washington , U.S, United States, Washington, San Francisco, Asia, U.S, China, America, China's

☆ Wegovy Is Shown to Reduce Risk of Heart Attacks and Strokes in Some Patients
▼ + stars: | 2023-11-11 | by ( Dani Blum | More About Dani Blum | ) www.nytimes.com time to read: +1 min

A pivotal new study suggests that the weight loss drug Wegovy cut the risk of heart attack, stroke or death from cardiovascular issues by 20 percent among overweight or obese people with heart disease — a striking benefit that could change the standard of care for these patients. “We’ve just identified a new best practice,” said Dr. Clyde Yancy, chief of the division of cardiology at Northwestern Medicine, who was not involved with the study. Drug companies see potential for the medicines that extends far beyond obesity. Outside of statins, she said, no medication has so dramatically reduced cardiovascular risk among people with heart disease. “The uptake of this drug is going to be skyrocketing in the next couple of years,” she said.

Persons: “ We’ve, ”, Clyde Yancy, Yuan Lu Organizations: Northwestern Medicine, American Heart Association, Yale School of Medicine Locations: Philadelphia, statins

☆ Novo Nordisk says Wegovy heart benefits due to more than weight loss
▼ + stars: | 2023-11-11 | by ( Patrick Wingrove | ) www.reuters.com time to read: +4 min

A 0.25 mg injection pen of Novo Nordisk's weight-loss drug Wegovy is shown in this photo illustration in Oslo, Norway, September 1, 2023. REUTERS/Victoria Klesty/Illustration/File Photo Acquire Licensing RightsPHILADELPHIA, Nov 11 (Reuters) - Novo Nordisk (NOVOb.CO) on Saturday said the heart protective benefits of its wildly popular Wegovy obesity treatment are due to more than weight loss alone, according to new data presented at a major medical meeting on Saturday. Given that patients had not started losing weight when the cardiovascular benefits first appeared suggests the heart protection was not purely the result of weight loss, Novo said. Though the trial was not conducted to test weight loss, participants lost an average of nearly 10% of their total body weight. Novo said patients in the heart study were not required to track diet and exercise as they are in obesity trials.

Persons: Victoria Klesty, Wegovy, Novo, Martin Lange, Lange, Eli Lilly's, Patrick Wingrove, Bill Berkrot Organizations: REUTERS, Rights, Novo Nordisk, American Heart Association, New England, of Medicine, Novo Nordisk's, U.S . Food, Drug Administration, Thomson Locations: Oslo, Norway, Victoria, Philadelphia, U.S, EU

☆ Eli Lilly’s Mounjaro Approved for Weight Loss in the U.S.
▼ + stars: | 2023-11-08 | by ( Peter Loftus | ) www.wsj.com time to read: 1 min

Earlier: Some drugs initially approved to treat Type 2 diabetes are now being used for cosmetic weight loss. WSJ’s Daniela Hernandez explains how they work, their side effects, and concerns over unintended consequences. Illustration: Elizabeth SmelovU.S. drug regulators have approved expanding the use of Eli Lilly ’s diabetes drug Mounjaro to include the treatment of obesity. The Food and Drug Administration’s decision Wednesday furthers the rapid rise of Mounjaro—and similar-acting therapies Ozempic and Wegovy from Novo Nordisk —that have in a matter of months reshaped the treatment of obesity and doctors’ understanding of its roots.

Persons: WSJ’s Daniela Hernandez, Elizabeth Smelov, Eli Lilly ’, Ozempic Organizations: Novo Nordisk Locations: Elizabeth Smelov U.S, Novo

The FDA approved tirzepatide for weight loss under the brand name Zepbound. It has been available as Mounjaro for type 2 diabetes since 2022 and had increasingly been used "off-label" for weight loss while the obesity approval was pending. Zepbound will be available in the U.S. by the end of the year at a list price of $1,059.87 a month, according to Lilly. That compares with a list of $1,349 per-package for Novo Nordisk's (NOVOb.CO) wildly popular weight-loss drug Wegovy. After Wednesday's FDA approval, Lilly can now promote the drug for weight loss.

Persons: Eli Lilly, Mike Segar, Eli Lilly's, ” John Sharretts, Lilly, Morningstar, Damien Conover, Conover, drugmaker, Robert Kushner, Mounjaro, Patrick Wingrove, Leroy Leo, Bhanvi, Shinjini Ganguli, Bill Berkrot Organizations: Company, REUTERS, U.S . Food, Drug Administration, U.S, FDA, FDA’s Center, Drug, Research, Novo Nordisk's, Reuters, Northwestern University Feinberg School of Medicine, Thomson Locations: Branchburg , New Jersey, U.S, Indianapolis, United States, New York, Bengaluru

SAN JUAN, Puerto Rico (AP) — One of Puerto Rico’s biggest distributors of pharmaceutical drugs was ordered to pay $12 million after being accused of not reporting hundreds of suspicious orders for controlled substances, the U.S. Justice Department said Monday. Drogueria Betances, LLC is accused of not reporting at least 655 orders for fentanyl and at least 113 orders for oxycodone from 2016 through June 2019. The orders were considered suspicious given in part their frequency and size, the department said. In addition, the company was ordered to improve its compliance program and report suspicious orders to the DEA, among other things. He added that Drogueria Betances never was accused of diverting controlled products to unauthorized people or entities.

Persons: Drogueria Betances, ” Juan Carlos Hernández Organizations: JUAN, Rico’s, U.S . Justice Department, U.S . Drug Enforcement, U.S Locations: Puerto Rico, U.S

☆ Eli Lilly says supply of blockbuster diabetes drug Mounjaro has improved in U.S.
▼ + stars: | 2023-11-02 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +3 min

Eli Lilly on Thursday said supply of its blockbuster diabetes drug Mounjaro has improved in the U.S. after months of widespread shortages. During an earnings call Thursday, Eli Lilly executives said the company experienced tight supply for Mounjaro throughout most of the third quarter. But U.S. product shipments of Mounjaro have recently increased, and inventory levels at U.S. drug wholesalers have improved, according to Eli Lilly CFO Anat Ashkenazi. Eli Lilly has also invested more than $3 billion to build two new manufacturing sites in its home state of Indiana. Eli Lilly's main rival in the weight loss drug space, Novo Nordisk , is still navigating its own supply constraints of diabetes drug Ozempic and obesity treatment Wegovy.

Persons: Eli Lilly, Mounjaro, Eli Lilly's, Anat Ashkenazi, Ashkenazi, David Ricks, Ricks, we're, Wegovy, Eli Lilly's Mounjaro Organizations: Novo Nordisk, Pharmacy, Food, Pfizer Locations: Provo , Utah, U.S, North Carolina, Indiana, Novo

Six of the 11 major S&P 500 sectors were trading lower, with information technology (.SPLRCT) leading losses. Pfizer's shares (PFE.N) fell 1.5% after the drugmaker reported its first quarterly loss since 2019. U.S. equities are tracking their third straight month in the red, with the S&P 500 (.SPX) and the Nasdaq (.IXIC) on course for their worst October since 2018. The Fed kicks off a two-day monetary policy meeting on Tuesday. The Fed's commentary on Wednesday would be crucial in assessing how long monetary policy could stay restrictive amid recent signs of economic strength.

Persons: Brendan McDermid, Andrew Hunter, Amruta Khandekar, Shashwat Chauhan, Saumyadeb Chakrabarty, Shounak Dasgupta, Maju Samuel Organizations: New York Stock Exchange, REUTERS, Corp, Dow, Nasdaq, Federal, Nvidia, Microsoft, Caterpillar, Chicago PMI, Capital Economics, Dow Jones, PDD Holdings, VF Corp, Vans, Arista Networks, Sarepta Therapeutics, NYSE, Thomson Locations: New York City, U.S, China, Bengaluru

☆ Merck quarterly profit tops expectations on COVID pill surprise
▼ + stars: | 2023-10-26 | by ( Michael Erman | ) www.reuters.com time to read: +2 min

The Merck logo is seen at a gate to the Merck & Co campus in Rahway, New Jersey, U.S., July 12, 2018. Merck raised Lagevrio full-year sales forecast to $1.3 billion. Third-quarter sales of Merck's top-selling cancer immunotherapy, Keytruda, stood at $6.34 billion, surpassing analysts' average estimate of $6.22 billion. Gardasil, its vaccine to prevent cancers caused by human papillomavirus (HPV), generated sales of $2.59 billion, rising 13% but missing analysts' average estimate of $2.69 billion. The company posted sales of $15.96 billion in the reported quarter, compared to the average analyst estimate of $15.3 billion.

Persons: Brendan McDermid, Molnupiravir, Merck, Wells, Mohit Bansal, drugmaker, Michael Erman, Leroy Leo, Bill Berkrot Organizations: Merck, Co, REUTERS, Merck & Co, Pfizer's, Thomson Locations: Rahway , New Jersey, U.S, Japan, United States, EU

Some Republican contenders for their party's 2024 presidential nomination have turned to a blunt policy proposal to tamp down on crime: killing criminals. Crime, meanwhile, is a greater concern for voters than it has been in previous elections, even as crime trends are mixed. The former president has reiterated previous calls for drug dealers to receive the death penalty, despite legal scholars questioning its constitutionality. For instance, the U.S. Supreme Court holds that the application of the death penalty for crimes that do not result in the death of the victim is generally unconstitutional. In 2008, the court left open the possibility of the death penalty for "drug kingpin activity," though it has never been applied.

Persons: Donald Trump, Jonathan Ernst, Trump, Doug Heye, David Kochel, Ron DeSantis, DeSantis, kingpins, Mike Pence, Pence, Bryan Griffin, they're, Thomas Zeitzoff, Gram Slattery, Nathan Layne, Tim Reid, Ross Colvin, Howard Goller Organizations: Des Moines, Iowa State Fairgrounds, REUTERS, Rights, Republican, Federal Bureau of, Reuters, Trump, U.S, Supreme, American University, Thomson Locations: U.S, Des Moines , Iowa, Mexico, United States, California, Florida, America, Indiana, Washington, Wilton , Connecticut, Los Angeles

☆ Exclusive: Lilly hires CordenPharma to make diabetes drug Mounjaro's active ingredient -source
▼ + stars: | 2023-10-19 | by ( Maggie Fick | ) www.reuters.com time to read: +3 min

An Eli Lilly and Company pharmaceutical manufacturing plant is pictured at 50 ImClone Drive in Branchburg, New Jersey, March 5, 2021. REUTERS/Mike Segar/File Photo Acquire Licensing RightsLONDON, Oct 19 (Reuters) - Eli Lilly (LLY.N) has hired Switzerland-based contract drugmaker CordenPharma to produce the active ingredient in its diabetes drug Mounjaro, a source familiar with the matter told Reuters on Thursday. Lilly has said it expects U.S. approval for Mounjaro for weight loss by the end of the year. The source told Reuters that CordenPharma's factory in Colorado is under contract to make tirzepatide, the active ingredient in the weekly injection. Analysts estimate the obesity market could be worth as much as $100 billion in the next decade.

Persons: Eli Lilly, Mike Segar, drugmaker, CordenPharma, Lilly, Corden, Maggie Fick, Josephine Mason, Bill Berkrot Organizations: Company, REUTERS, Reuters, CordenPharma, Novo Nordisk, Mounjaro, Thomson Locations: Branchburg , New Jersey, Switzerland, United States, Colorado, Basel, Europe, Boulder , Colorado, Boulder

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