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☆ Small ears, frizzy hair and dry ear wax - the genetics of mammoths
▼ + stars: | 2023-04-07 | by ( Will Dunham | ) www.reuters.com time to read: +4 min

Researchers on Friday said they had analyzed the genomes of 23 woolly mammoths - including 16 newly sequenced ones - based on remains preserved in Siberian permafrost. "We find that woolly mammoths had molecular adaptations in genes related to coping with cold Arctic environments, such as thick fur, fat storage and metabolism, and thermal sensation, among others," Díez-del-Molino added. Woolly mammoths were about the size of modern African elephants, around 13 feet (4 meters) tall, but had much smaller ears to guard against losing body heat from a larger ear surface. One of them in humans is associated with Uncombable Hair Syndrome, a condition characterized by dry and frizzy hair that cannot be combed flat. The study helped clarify variable shades of mammoth hair color - brownish with a touch of red.

☆ I began selling stickers on Etsy as a fun hobby and now make 6-figures from my business. Here's how I got started.
▼ + stars: | 2023-04-07 | by ( Dorothy Cucci | ) www.businessinsider.com time to read: +7 min

Jenkinson makes hundreds of thousands of dollars a year from selling stickers and courses. Mim JenkinsonI wanted a creative hobby to keep my mind occupied, so I started to make stickers for my planner. A few months after I started, I started getting questions from customers about how I was making the stickers. I aim to find out what I can make easier for them, whether they're buying or making stickers. I would never have imagined that selling stickers would've had the impact that it's had on my life.

☆ Why fighting the urge to sleep may be bad for our health
▼ + stars: | 2023-04-07 | by ( ) www.reuters.com time to read: +17 min

What happens when we sleep Sleep itself has cycles, in which the brain and body move through phases, marked by varying brain activity. Moving into REM sleep A region in the upper brainstem kickstarts the move into REM sleep. Waking up After cycling through non-REM and REM sleep around 4 to 5 times, the basal forebrain and other structures receive signals to start exiting sleep. Then we transition back to lighter sleep, into REM sleep and back down again, and so on until we wake up. Tips for better sleep Good sleep habits can contribute to better sleep, studies have found.

☆ They Had $350,000 and a Dream to Live Together. Could They Make It in Manhattan?
▼ + stars: | 2023-04-06 | by ( Joyce Cohen | ) www.nytimes.com time to read: +3 min

For 30 years, Ms. Denlinger rented a sunny fifth-floor walk-up in Manhattan Valley. Ms. Ladin, 62 — the first openly transgender professor at Yeshiva University, where she taught English — suffers from myalgic encephalomyelitis, also known as chronic fatigue syndrome. “I had not done any real estate hunting for 30 years,” Ms. Denlinger said. To find her Manhattan Valley apartment, “I got a Village Voice, looked in the ads, called up the landlord and made an appointment. “We needed two rooms that could be really separate, where one was not a bathroom or a kitchen,” Ms. Ladin said.

☆ I make $15,000 in ad revenue a month through podcasts. Here’s how I started my network on Instagram.
▼ + stars: | 2023-04-06 | by ( Vartika Puranik | ) www.businessinsider.com time to read: +6 min

Gillian Tietz is the founder of Sober Powered Media and the host of the "Sober Powered" podcast. The seven shows in her network bring in about $15,000 in ad revenue and 400,000 downloads a month. I named it the "Sober Powered" podcast, created an Instagram account, and started working on it every day. I resigned from my full-time job in June and officially launched Sober Powered Media, a podcast network that includes my show. I now monetize other podcasts through my network in exchange for 20% of the ad revenue, and I have seven podcasts in my network.

☆ Pfizer RSV vaccine for older adults should be monitored for nervous system condition Guillain-Barre, scientists say
▼ + stars: | 2023-04-06 | by ( Spencer Kimball | ) www.cnbc.com time to read: +2 min

A health worker prepares a flu vaccine shot before administering it to a local resident in Los Angeles, the United States, on Dec. 17, 2022. People who receive Pfizer 's RSV vaccine for older adults should be monitored for Guillain-Barre syndrome, after two people developed the nervous system disorder after they received the shot, scientists said in clinical trial results published in the New England Journal of Medicine. The scientists concluded the vaccine was effective in preventing lower respiratory tract illness in adults ages 60 and older without any evident safety concerns. But they flagged the Guillain-Barre cases as a potential cause for concern moving forward. Guillain-Barre syndrome is a rare disorder in which the body's immune system mistakenly attacks the nerves.

☆ Work-Life Balance Is Harder to Find Thanks to Pandemic and Office Mandates
▼ + stars: | 2023-04-06 | by ( Kelli María Korducki | ) www.businessinsider.com time to read: +14 min

The insidious creep of job burnout was inescapable when I spoke with more than a dozen ambitious midcareer women for an article last winter. While work friendships can stifle loneliness, the centrality of a job in American social life does not bode particularly well for Americans' work-life balance. For those who've put all their eggs in the proverbial basket of their job, Koretz said, these times of transition can trigger a kind of identity crisis. The idea is that you just work and work and work and work and work. Workers can also take small steps toward improving their work-life balance by setting aside time each day and each week for nonwork priorities.

☆ These Drugs Are So Futuristic That Doctors Need New Training
▼ + stars: | 2023-04-05 | by ( Amy Dockser Marcus | Photographs Lyndon French For The Wall Street Journal | ) www.wsj.com time to read: 1 min

A major obstacle looms for the drugs of the future. Not enough doctors know how to administer them. For just one rare neurodevelopmental disorder, known as Angelman syndrome, clinical trials are testing four cutting-edge therapies. Twenty more research programs are under way and could yield treatments ready to move into human testing in the next several years, according to Allyson Berent-Weisse, chief scientific officer of the Foundation for Angelman Syndrome Therapeutics, or FAST, and the mother of a child with the disorder.

☆ Barbara Corcoran says every successful person she knows has imposter syndrome: 'That's what drives them'
▼ + stars: | 2023-04-03 | by ( Megan Sauer | ) www.cnbc.com time to read: +4 min

Corcoran, an entrepreneur and longtime investor on ABC's "Shark Tank," cited herself an example. And on "Shark Tank," it leads her to seek out entrepreneurs who question themselves. "Everyone's got self-doubt," Corcoran said. It may even be a shared experience among "Shark Tank" investors. Disclosure: CNBC owns the exclusive off-network cable rights to "Shark Tank."

☆ NHL roundup: Carter Verhaeghe nets career-best 4 goals in Panthers' win
▼ + stars: | 2023-04-02 | by ( ) www.reuters.com time to read: +9 min

Sabers 6, Flyers 3Alex Tuch scored his second career hat trick to help Buffalo to a win against host Philadelphia. Morgan Frost scored twice and Felix Sandstrom made 23 saves for the Flyers, who had their seven-game point streak snapped. Avalanche 5, Stars 2Nathan MacKinnon had two goals, Mikko Rantanen had a goal and three assists, and host Colorado beat Dallas. Ben Hutton, Zach Whitecloud and Brett Howden also notched goals for Vegas, which is 5-1-1 in its past seven games. J.J. Moser and Milos Kelemen scored for the Coyotes (27-37-13, 67 points), who have dropped seven straight games (0-5-2).

This valuation comes after a rich global history showcasing wars fought over salt, trade routes built for commodities, taxes levied against the mineral and even cities named in sodium's legacy. "You could not have an international economy if you didn't have salt," Mark Kurlansky, author of "Salt: A World History," told CNBC. "We're seeing that the majority is deicing salt," Seth Goldstein, equities analyst with Morningstar, told CNBC. However, if too much salt permeates our environment, the effects can be dangerous, according to the Environmental Protection Agency. Runoff from deicing salts that keep our roads safe in wintry weather is the most obvious way that salt enters the environment.

☆ Walmart sued by EEOC for firing deli worker with Crohn's disease
▼ + stars: | 2023-03-28 | by ( Noah Sheidlower | ) www.cnbc.com time to read: +3 min

Equal Employment Opportunity Commission sued Walmart for firing a North Carolina employee with Crohn's disease after the retail giant allegedly refused to grant her disability-related leave. The EEOC's complaint, filed in Charlotte federal court, accuses Walmart of violating the Americans with Disabilities Act in its treatment of deli worker Adrian Tucker. Tucker worked for Walmart between February 2014 and April 2017 at its Statesville store. According to the complaint, Tucker suffers from Crohn's disease, a chronic bowel condition that causes inflammation of the digestive tract, which can lead to stomach cramps, dehydration, vomiting and diarrhea. The EEOC alleges Walmart refused to provide reasonable accommodation to her when she experienced symptoms multiple times between November 2016 and April 2017.

If you have a food allergy, you're likely aware of it by now. Many people are allergic to nuts and shellfish, and were either born with the allergy or developed it with age. Despite how careful you might be with the foods you're allergic to, it is possible that you're still consuming foods every day that your body is sensitive to in other ways. On the flip side, "food sensitivities are very different [and] take longer to generate," says Hart. Food sensitivities are also known as food intolerances, and "reactions tend to be long-term and chronic," she adds.

☆ 5 ways to cope with layoff anxiety and how to stop worrying you’re next
▼ + stars: | 2023-03-25 | by ( Melody Wilding | ) www.businessinsider.com time to read: +8 min

With layoffs seemingly in every major industry, it's natural to feel some layoff anxiety. Layoff anxiety is high among workers. What to do when layoff anxiety is consuming your thoughts1. Ask yourself:What would I do if I'm laid off? Layoff anxiety can stop you in your tracks.

March 24 (Reuters) - The U.S. Food and Drug Administration (FDA) on Friday approved Pharming Group's drug to treat a rare genetic disorder that leads to a weakened immune system, the Dutch company said. APDS causes a lack of functioning immune cells, B cells and T cells, which makes it difficult for people with this disorder to fight off bacterial and viral infections. At least two analysts expected the drug to be priced at as much as $400,000. Oppenheimer analyst Hartaj Singh expected Joenja to be priced between $250,000 and $400,000, and forecast peak sales of $200 million to $300 million, ahead of the approval. Joenja is an oral drug that targets and blocks a form of the protein called phosphoinositide 3-kinase delta (P13K).

☆ Microsoft CEO Satya Nadella’s No. 1 tip for career success—if you don’t do this, ‘you can’t grow’
▼ + stars: | 2023-03-24 | by ( Morgan Smith | ) www.cnbc.com time to read: +3 min

Microsoft CEO Satya Nadella never expected to lead one of the world's largest, most powerful tech companies — he was just excited to work there, period. One of the most important lessons he learned in his decades at Microsoft — and his "best career advice" — is simple: "Don't wait for your next job to do your best work." Throughout his tenure at Microsoft, Nadella had to constantly adapt depending on the teams he worked with and the divisions he managed, all while keeping pace with fast-changing technologies. "You cannot grow if you don't think your growth comes because of what you're doing," he added. If you're feeling stuck at work or struggling to find meaning in your job, Nadella has advice for that, too.

☆ I'm a former Google recruiter. Here's how to land a job in tech — and what can blow your interview (edited)
▼ + stars: | 2023-03-24 | by ( Dorothy Cucci | ) www.businessinsider.com time to read: +6 min

This as-told-to essay is based on a conversation with Jeff Sipe, a private tech career coach and former Google recruiter. Big Tech layoffs were always going to receive backlash — that said, I don't think any of them have been handled perfectly, and many of them could have been avoided. Yes, companies needed to cut down on costs, but more than that, I think layoffs have become trendy. After layoffs, the company's stock price usually goes up, and the board of directors and shareholders (most of whom don't work there) are happy. Anyone can create one for free, using Canva for example, that says, "Impacted by Google Layoffs."

☆ Leadership Advice and Management Regrets From WSJ’s Women in the Workplace Forum
▼ + stars: | 2023-03-23 | by ( Ray A. Smith | ) www.wsj.com time to read: 1 min

One of the problems with being a boss is it can be a lonely and sometimes uncomfortable place, despite the pay and the perks. Four women in leadership spanning business, politics and entertainment—and ranging in age from their 20s to their 80s—offered their best leadership advice to guests gathered for The Wall Street Journal’s Women in the Workplace Forum this week in New York City. They used terms such as “idea volcanoes” and spoke about their own impostor syndrome, hoping examples of their successes and regrets would help others.

Christopher Willard | Walt Disney Television | Getty ImagesOn the advantage of being an underdog: I grew my business in a man's world. There were no businesses in New York City, especially in real estate, that were owned by women. There weren't any women role models, and the men weren't very forthcoming [with advice]. When I was just starting out, I went to a community business event and none of the men would even talk to me. On why she likes to partner with women in business: Women are more willing to listen [than men], and they're not as cocky they'll be an instant success.

☆ Americans desperate for the hot weight-loss drug Ozempic are turning to Canada and Mexico because they can't afford it at home
▼ + stars: | 2023-03-20 | by ( ) www.businessinsider.com time to read: +12 min

She found CanShipMeds.com, one of many websites that says it ships a similar drug, Ozempic, from Canada at a lower cost. Delp is hardly the only American searching for weight-loss drugs across the border in Canada or Mexico. Medicare, the federal program that provides health coverage for people 65 and older, doesn't cover weight-loss drugs at all, though there's a push to change that. People are looking to Canada and Mexico for cheaper OzempicCrystal Cox/Business InsiderUntil insurance coverage improves, people will look abroad to afford the weight-loss drugs. Want to tell us about your experience with weight-loss drugs like Ozempic and Mounjaro?

☆ U.S. judge in Texas will soon rule on the abortion pill mifepristone. Here's what could happen
▼ + stars: | 2023-03-17 | by ( Spencer Kimball | ) www.cnbc.com time to read: +7 min

The Alliance For Hippocratic Medicine wants Judge Kacsmaryk to nullify the FDA's medical approval of mifepristone, which would effectively ban the abortion pill across the US. Senate Judiciary Committee | YouTubeA Texas judge will soon issue a pivotal ruling in a closely watched case challenging the Food and Drug Administration's approval of the abortion pill mifepristone. It's also possible that Kacsmaryk could order the agency to impose tighter restrictions on access to mifepristone but stop short of completely halting sales. Abortion rights groups and legal experts expect the judge will rule against the FDA in some form. Possible injunctionIf Kacsmaryk issues an order to withdraw mifepristone from the market, there are several ways such a ruling could be drafted.

☆ 8 questions with Instagram's 'it girl' Matilda Djerf, who started a $34 million fashion empire at 22 years old
▼ + stars: | 2023-03-16 | by ( Dorothy Cucci | ) www.businessinsider.com time to read: +6 min

Djerf co-founded the fashion brand Djerf Avenue in 2019; it made $34 million in sales last year. This Q&A is based on a conversation with Matilda Djerf, a 25-year-old influencer and founder of the fashion brand Djerf Avenue, which made $34 million in sales in 2022. "Apart from the creative and the design, I really didn't know what we were doing at first." Apart from the creative and the design, I really didn't know what I was doing at first. What are some of the biggest lessons you've learned since founding Djerf Avenue, and what are your ambitions for the brand?

☆ Chinese Doctor Who Sounded the Alarm on SARS Dies
▼ + stars: | 2023-03-15 | by ( Liyan Qi | ) www.wsj.com time to read: 1 min

Military surgeon Jiang Yanyong, who challenged China’s official line about SARS, has died at age 91. Jiang Yanyong , a military surgeon who sounded the alarm on Chinese authorities’ efforts to cover up the extent of a 2003 outbreak of severe acute respiratory syndrome, or SARS, died over the weekend at age 91, according to people close to Dr. Jiang and his family. Unlike Li Wenliang , a Wuhan doctor who was initially punished for circulating an early warning about the spread of Covid-19 before his death from the disease in 2020, Dr. Jiang wasn’t penalized for drawing attention to the impact of SARS in 2003. Both doctors were eventually hailed as folk heroes in state media.

☆ U.S. FDA approves Acadia's Rett syndrome drug
▼ + stars: | 2023-03-14 | by ( ) www.reuters.com time to read: +3 min

The approval comes months after the FDA declined to approve expanded use of Acadia's drug Nuplazid to treat psychosis related to Alzheimer's disease. Acadia said it plans to make the drug available to patients by the end of April. He forecast peak U.S. trofinetide sales of $487.2 million by 2035. After the FDA declined to approve the expanded use of Nuplazid, Acadia said it would not pursue that indication for Nuplazid further. Improvement of symptoms was measured according to the assessment scales Rett Syndrome Behaviour Questionnaire and the Clinical Global Impression of Improvement.

☆ Another 55 amateur players join concussion lawsuit
▼ + stars: | 2023-03-14 | by ( Lori Ewing | ) www.reuters.com time to read: +4 min

MANCHESTER, England, March 14 (Reuters) - Another 55 amateur rugby players who are suffering from neurological impairments joined the growing list of claimants in a class-action concussion lawsuit on Monday, claiming that the sport's governing bodies failed to take reasonable action to protect them. "The players we represent love the game," Rylands Garth said in a statement. "(CTE) is a cruel and progressive degenerative disease of the brain found in many players of contact sports leading to repetitive brain trauma," they said. World Rugby pointed to studies in France and South Africa that showed positive advancements in terms of player safety and overall game experience. In 2019, the NHL paid $18.49 million to settle a concussion lawsuit brought by more than 100 players.

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