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From the best of times, to the worst of times: The market for initial public offerings has fallen off a cliff in 2022. The decline has been striking given the record level of proceeds raised through public markets just a year prior. U.S.-listed companies raised over $155 billion in proceeds in 2021 through their initial public offerings, according to data from EY and Dealogic. Part of the clog in the IPO pipeline has been caused by the dismal performance of companies that went public in 2021, Gerring said. Watch the video above to find out how the IPO market went from boom to bust in 2022, and whether experts forecast a rebound in 2023.

☆ The IPO market went from 'boom to bust' in 2022. Here's what's driving the massive slowdown
▼ + stars: | 2022-09-23 | by ( Noah Higgins-Dunn | ) www.cnbc.com time to read: +2 min

☆ Embattled CEO Werner Baumann enters his final chapter at Bayer, aiming to turn the German pharma giant into a cancer powerhouse
▼ + stars: | 2022-09-22 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +6 min

With a successor search underway, Werner Baumann is entering his last chapter as Bayer's CEO. Baumann told Insider he's more excited today about Bayer's future than several years ago. The exec wants Bayer to become a top 10 cancer player by 2030, and recently opened a Cambridge lab. CAMBRIDGE, Massachusetts — Within his first month as CEO of the German giant Bayer, Werner Baumann took a big, legacy-making swing. Baumann says Bayer's future is in oncologyWerner Baumann, right, CEO of Bayer, and Werner Wenning, chairman of the Supervisory Board of Bayer.

☆ We went inside the lab at Vertex, a company that dodged the market downturn to become one of the best-performing biotechs of 2022
▼ + stars: | 2022-09-21 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +10 min

A mosaic of human cells inside Vertex Pharmaceuticals' cell and gene-therapy laboratory. The four-story, 267,000-square-foot space is home to Vertex's cell and gene-therapy unit, with about 375 people now residing in the modern-industrial building. That has led to going after unrelated diseases like sickle cell, diabetes, muscular dystrophy, kidney disease, and pain. For instance, Vertex's approach to sickle cell is led by its CRISPR gene-editing program. Vertex PharmaceuticalsThe next test of Vertex's strategy will be an experimental treatment called exa-cel, its CRISPR gene-editing program for sickle cell.

☆ Prolific unicorn backer Brad Svrluga dishes on the 'lower valuations' and 'long waits for funding' that await founders this fall
▼ + stars: | 2022-09-20 | by ( Madeline Renbarger | ) www.businessinsider.com time to read: +3 min

For Brad Svrluga, cofounder and general partner of VC firm Primary, venture deals are ramping up. Here's why he thinks this new normal is good for founders, who need to set "rational expectations." Startup founders and venture capitalists across the country have begun to see signs of a fall comeback after the first summer slowdown in two years. In 2021, the hyper-competitiveness of the market meant that VCs were offering some startups term sheets in a matter of minutes. Still, for early-stage founders looking to raise today, the days of easy money and competing term sheets are gone.

☆ Santander hires law firm to investigate bankers' strip club visit
▼ + stars: | 2022-09-19 | by ( Jesús Aguado | ) www.reuters.com time to read: +2 min

Register now for FREE unlimited access to Reuters.com RegisterMADRID, Sept 20 (Reuters) - Spanish bank Santander (SAN.MC) hired a law firm to investigate a whistleblower report saying a group of bankers visited a strip club after a day of company meetings and pressured younger colleagues to join them, a source close to the matter said. Santander responded by hiring U.S. law firm Gibson Dunn to conduct an internal investigation over the summer, Reuters' source said. The law firm interviewed several people involved in the night out and concluded there had not been explicit pressure exerted on junior staff members, the source added. The Financial Times reported that no one has been dismissed as yet, but one manager has been disciplined. A Gibson Dunn representative was not immediately available for comment and the UK's Financial Conduct Authority said it is unable to comment on individual cases.

☆ Wall Street's biggest investors can't shake a nightmare about the US economy. And that fear is much worse than a recession.
▼ + stars: | 2022-09-18 | by ( Aaron Weinman | ) www.businessinsider.com time to read: +5 min

Talk of a recession, rough inflation data, and the persistent increase in costs of certain staple goods has got Wall Street's biggest investors living in fear of an economic nightmare. Wall Street has been hit by a brutal market sell-off this year. Wall Street investors fear an economic nightmare. BMO Capital Markets is cutting jobs amid the broader downturn in dealmaking, according to Bloomberg. Private-equity investment firm Corsair has made an investment in Miracle Mile Advisors, a wealth advisory firm based in Los Angeles.

☆ Biden aides are quietly assembling a 2024 campaign as they await a final decision on his political future
▼ + stars: | 2022-09-16 | by ( Https | Media-Cldnry.S-Nbcnews.Com Image Upload Newscms Carol-Lee-Circle-Byline-Template.Jpg | Carol E. Lee | ) www.nbcnews.com time to read: +10 min

But, they said, if Republicans win one or both chambers, that would likely trigger a quicker pivot to a Biden re-election campaign. Relying on the party apparatus would allow the Biden campaign to forgo trying to build up its own separate campaign infrastructure in each state. But while a DNC-centric campaign might seem to be a natural fit for Biden, relying on the committee poses risks. “The Biden approach is the more traditional approach.”Far more than Obama, Biden is a creature of the Democratic Party. Biden aides say no final decisions on campaign staffing have been made, and they’re not expected to be until after the midterms.

☆ Why a top Roche scientist is leaving after 25 years to join a rising biotech startup using fungi to make new drugs
▼ + stars: | 2022-09-16 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +5 min

After 25 years at the pharma giant Roche, the drug hunter Martin Stahl is leaving to join a biotech. CAMBRIDGE, Massachusetts — A longtime drug-hunting veteran is leaving one of the largest drugmakers to lead the science division at the biotech startup LifeMine Therapeutics, Insider has learned. FogPharmaThe big draw for Stahl was LifeMine's approach to discovering drugs. With its genetic-database approach, LifeMine hopes to greatly speed up how long it takes to develop fungi-derived drugs. Stahl said LifeMine's approach leaned on nature, rather than medicinal chemists, to design the drugs.

☆ Patagonia's CEO gets candid: How sustainability, diversity, and social justice guide the beloved brand
▼ + stars: | 2022-09-15 | by ( Rebecca Knight | ) www.businessinsider.com time to read: +12 min

As CEO of Patagonia, Ryan Gellert wrestles with a paradox: The outdoor-gear maker's good works, philanthropy, and intentions are still not enough to justify its existence. To Gellert, who took over from the widely respected Rose Marcario, the company could always be doing more. And we need business to step up. Patagonia really struggled in Europe, and that never made sense to me. One of the things that I love more than anything about Patagonia is that we are an unapologetically for-profit business.

☆ See the 20-slide presentation this biotech startup used to raise $75 million for a way to treat blindness with CRISPR
▼ + stars: | 2022-09-14 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +2 min

About a year ago, the startup secured an exclusive deal with CRISPR gene-editing leader Intellia. SparingVision, a Paris-based startup, just raised $75 million to advance a suite of gene-therapy and gene-editing programs to treat eye diseases. The company plans to use the funds to enter the clinic with its first gene-therapy program. The cash will also help advance SPVN50, SparingVision's first gene-editing program. The program came out of a research collaboration SparingVision struck with Intellia Therapeutics, a CRISPR gene-editing leader, last year.

☆ A step-by-step guide to securing a Big Law summer associate position, from networking best practices to acing the interview
▼ + stars: | 2022-09-14 | by ( Business Insider | ) www.businessinsider.com time to read: +3 min

Working at a law firm after a student's second year, or 2L, has long been a rite of passage for students bound for Big Law. And some students are finding themselves ill-equipped to navigate what one law partner has dubbed "the Wild West" of Big Law recruiting. The former pro soccer player recently walked Insider through his sometimes harrowing journey to snagging multiple Big Law offers before on-campus interviewing, or OCI, even began. The perks including increasingly big paychecks, especially for what are known as "rainmakers," or law partners who bring in big business. This Big Law firm is so hungry for associates that it's giving $75,000 referral bonusesBig Law has a mental health problem.

☆ 2 Gibson Dunn partners outlines the traits they look for and the questions they ask in recruiting summer associates
▼ + stars: | 2022-09-13 | by ( Peter Coutu | ) www.businessinsider.com time to read: +5 min

Gibson Dunn is one of the nation's most prestigious law firms. Gibson Dunn is ranked 12th in The American Lawyer's list of top law firms by revenue, pulling in $2.16 billion in revenue last year. Show that you're collaborativeJura said Gibson Dunn prides itself on being a great place to work, with a communal and supportive environment for all staffers. Ask questions about the firmJura said that students should not be afraid to ask questions about the firm. Asking questions can help candidates show a genuine interest in Gibson Dunn specifically.

☆ I'm a law student who managed to snag 2 job offers from prestigious firms before on-campus recruiting even began. Here's how I did it.
▼ + stars: | 2022-09-12 | by ( Jack Newsham | ) www.businessinsider.com time to read: +9 min

A former pro athlete and first-gen law student, he started networking before school started. David Ako Abunaw III is a former professional athlete and a student at the University of Pennsylvania's law school. But I feel like it's common for law students to be very type A, so that's never going to be me. Networking with law firms was key to getting early interviews and offersI started networking before law school. I spoke with people at several law firms, either UPenn graduates or people I had something else in common with.

☆ Gregg Costa, a judge who quit the conservative Fifth Circuit appeals court, is joining the law firm Gibson Dunn
▼ + stars: | 2022-09-03 | by ( Jack Newsham | ) www.businessinsider.com time to read: +4 min

Former federal judge Gregg Costa is about to join Gibson Dunn in a senior role, Insider has learned. Gregg Costa, a prosecutor-turned-federal judge who announced that he would return to private practice earlier this year, is joining Gibson Dunn, a person familiar with the matter told Insider. Costa clerked for the conservative Supreme Court justice William Rehnquist and was appointed by President Barack Obama, first as a district court judge in Galveston, Texas and later as an appeals judge. Before becoming a judge, Costa was an associate attorney at the law firm Weil Gotshal & Manges and a federal prosecutor in the Southern District of Texas. Federal courts in Texas and the Fifth Circuit have been top legal battlegrounds for President Joe Biden.

☆ Rental red flags: Here's what to look for to avoid ending up with a 'nightmare' apartment
▼ + stars: | 2022-09-01 | by ( Jordan Hart | ) www.businessinsider.com time to read: +5 min

Smith — who rented her apartment unseen before a cross-country move from Texas — told Insider she fell victim to misleading photos and an inaccurate description of her Manhattan apartment on a popular apartment hunting site. With Smith's story in mind, here are some key red flags to avoid during your search. The goal, according to Sanai, is to "pump the fear and pressure" prospective renters into signing a lease. Just because an apartment looks good at first glance doesn't mean you should submit an application right away. "You don't want to end up in a situation where you're tied to these people who're looking for any opportunity to get more money out of you," Smith told Insider.

☆ Famed litigator Randy Mastro is joining King & Spalding after more than 20 years of representing big clients for Gibson Dunn, from Chris Christie to James Dolan
▼ + stars: | 2022-08-16 | by ( Jack Newsham | ) www.businessinsider.com time to read: +4 min

Randy Mastro, a fixture at Gibson Dunn since 1998, is leaving the firm, four people told Insider. Star attorney Randy Mastro is leaving Gibson Dunn & Crutcher after more than 20 years, four people told Insider. Mastro has spent more than two decades at Gibson Dunn, which he first joined in 1989. By 2014, Chevron had run up a $32 million tab with Gibson Dunn, a bill it tried to make Donziger pay, according to Reuters. Do you know Randy Mastro or more about why he left Gibson Dunn?

Amira Barger, 35, is helping healthcare become a more diverse and inclusive industry. Amira Barger. Courtesy of Amira BargerGrowing up in a missionary family in Guam, Amira Barger knew she wanted to do something with her life that brought goodness into the world. "COVID made the field of pharma and healthcare really look introspectively at their programs and the way they do their work," she said. If there is one thing that Barger wished her clients knew, it is that DEI impacts everyone across the healthcare sector, no matter their race, disability, sexual orientation, or position in the C-suite.

Persons: Amira Barger, Barger, She's, COVID, — Leah Rosenbaum Organizations: Centers for Disease Control, Federal Emergency Management Agency, Pfizer, Kaiser Permanente, pharma Locations: Guam, Kaiser

☆ (video) Recomandări de la Mircea, fără spoilere: cinci filme despre prietenie, care îți vor frământa sufletul
▼ + stars: | 2021-06-12 | by ( Onixmedia Srl | ) diez.md time to read: +7 min

Aș mai adaugă că prietenii sunt și ceea ce îți rămâne dacă îți pierzi familia sau chiar dacă pierzi totul. Adam & Paul (2004)Este filmul de debut al regizorului Irlandez Lenny Abrahamson, cunoscut mai târziu pentru filmele „Frank” și Room. Pelicula urmărește o zi din viața a doi tineri dependenți de heroină, Adam (Mark O’Halloran, care este și scenaristul acestei producții) și Paul (Tom Murphy). Dar nu durează mult până când Frank își dă seama că robotul poate fi ușor manipulat pentru al ajuta în ceea ce-i place lui mai mult – furtul. Este o comedie frumoasă, cu multe substraturi, cu multe divergențe între tată și fiu, cu tradiție și progres, cu bătrânețe și tehnologie.

Persons: Constant Gardener, brazilianul Fernando Meirelles, Bergoglio, Jonathan Pryce, Papa Benedict al XVI, Anthony Hopkins, Papa Benedict, Adam, Paul, Lenny Abrahamson, Frank, Mark, Tom Murphy, Hunter, James Marsden, Liv Tyler, Susan Sarandon, Alzheimer ., neseparat, Hulu, Stan & Ollie, Stan, Steve Coogan, Ollie, John C . Reilly, Laurel, Hardy, Clint Eastwood, Hilary Swank, Morgan Freeman ., Maggie Fitzgerald, Frankie Dunn, Maggie, Frankie Organizations: Amazon Locations: Roma, Vaticanului, Dublin, Cold, New York, Liv, Turkmenistan, Britanie

☆ (video) 20 cele mai bune filme care au luat Oscarul din 2000 încoace. În acest an, premiile vor fi acordate în aprilie
▼ + stars: | 2021-01-22 | by ( Onixmedia Srl | ) diez.md time to read: +8 min

(video) 20 cele mai bune filme care au luat Oscarul din 2000 încoace. Marele general roman Maximus a condus din nou legiunile spre victorie pe câmpul de luptă. Invidios pe Maximus, moștenitorul tronului, Commodus, ordonă execuția sa și a familie sale. Înfruntând niște încercări, care i-ar fi pus la pământ pe alții, Nash revine la viață și în activitate datorită ajutorului soției sale, Alicia. În laboratorul guvernamental ascuns de securitate în care lucrează, singuratica Elisa este prinsă într-o viață izolată.

Persons: Ma, Ridley Scott, Maximus, Marcus Aurelius, Commodus, John Forbes Nash . Chipeșul, Nash, Alicia, Roxie Hart, Roxie, Velma Kelly . Roxie, Sauron, Aragorn, Maggie Fitzgerald, Frankie Dunn, Billy Costigan, Queenan, Costigan, Frank Costello, Joel, Ethan Coen, Cormac Mccarthy, Jamal Malik, Jamal, George al VI - lea, Lionel Longue, George Valentin, Riggan Thomson, Michael Keaton, Elisa Organizations: Pulitzer, Broadway, Boston Globe Locations: Chicago, Gondor, Minas Tirith, L.A ., Los Angeles, american, indian Mumbai, Irak, localnic, America, coreean

☆ (video) Toate lungmetrajele care au câștigat Oscarul la categoria cel mai bun film, din 2000 încoace
▼ + stars: | 2020-01-20 | by ( Onixmedia Srl | ) diez.md time to read: +8 min

(video) Toate lungmetrajele care au câștigat Oscarul la categoria cel mai bun film, din 2000 încoaceA rămas mai puțin de o lună până la cea de-a 92-a ceremonie a premiilor Oscar. Dacă ați vizionat deja toate filmele nominalizate într-o categorie sau alta, atunci echipa #diez vă propune o listă cu toate lungmetrajele care au câștigat Oscarul la categoria cel mai bun film, din 2000 încoace. Marele general roman Maximus a condus din nou legiunile spre victorie pe câmpul de luptă. Înfruntând niște încercări, care i-ar fi pus la pământ pe alții, Nash revine la viață și în activitate datorită ajutorului soției sale, Alicia. În laboratorul guvernamental ascuns de securitate în care lucrează, singuratica Elisa este prinsă într-o viață izolată.

Persons: Ridley Scott, Maximus, Marcus Aurelius, Commodus, John Forbes Nash . Chipeșul, Nash, Alicia, Roxie Hart, Roxie, Velma Kelly . Roxie, Sauron, Aragorn, Maggie Fitzgerald, Frankie Dunn, Billy Costigan, Queenan, Costigan, Frank Costello, Joel, Ethan Coen, Cormac Mccarthy, Jamal Malik, Jamal, George al VI - lea, Lionel Longue, George Valentin, Riggan Thomson, Michael Keaton, Elisa Organizations: Pulitzer, Broadway, Boston Globe Locations: Hollywood, Chicago, Gondor, Minas Tirith, L.A ., Los Angeles, american, indian Mumbai, Irak, localnic, America

But even though she only pays $600 a month for rent, she still plans to buy a house with higher costs in the next five years because she wants to feel like she's really home. (Two years ago, I left that job and was able to move back into my friend's home for the job I'm in now, as a magazine editor in the superyacht industry.) If all goes according to plan, we will save up enough money to buy a house within the next five years. After the wedding takes place, we'll save between $1,000 and $1,200 each month to put towards a house. But I have also lived the easygoing life of a renter and it's been an ideal scenario for me.

☆ I took Yale's 'most popular class ever'—and it completely changed how I spend my money
▼ + stars: | 2019-05-13 | by ( Dave Schools | ) www.cnbc.com time to read: +5 min

So when Yale released its happiness class for free online, I decided to give it a try. The 10-week class, called "The Science of Well-Being," is taught by Laurie Santos, a professor of psychology and cognitive science. She starts the class by addressing why the things we want in life don't actually make us happy. Money ≠ happiness. Be more mindful about how you spend moneyLater in the class, Santos interviews Elizabeth Dunn, a happiness researcher and the co-author of "Happy Money."

☆ ‘Murder in Boston: Roots, Rampage & Reckoning’ Review: In Pursuit of an Imaginary Assailant
▼ + stars: | 1989-10-23 | by ( John Anderson | ) www.wsj.com time to read: +2 min

He had identified a suspect in a lineup; he had involved his own brothers in his coverup; he failed to confess his guilt even in his suicide note. (“Shoddy,” says then-Boston Herald reporter Michelle Caruso , still penitent about her own failure to crack what she regards as an obvious case.) (Mr. Severino and TV reporter Jack Harper help reconstruct the search for Stuart’s car, which was accomplished by triangulating emergency sirens over police radios; it is electrifying.) Stuart claimed the killer fled into the nearby Mission Hill housing project. From that moment, says activist and Mission Hill resident Ron Bell , “it was open season on black people.”

Persons: Carol, Charles Stuart Photo, Jason Hehir, Charles Stuart, “, Tobin, HBO “ We’ll, Carol Stuart, ”, Bill Dunn, Hehir, Michelle Caruso, Stuart, Richard Severino, Severino, Jack Harper, Ron Bell Organizations: HBO, Mr, Boston Herald, Mission Hill Locations: Boston, Mission

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