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In 2022, drugmakers raised prices on more than 1,400 drugs according to data published by 46brooklyn, a drug pricing non-profit that is related to 3 Axis. The median drug price increase was 4.9% last year, while the average increase was 6.4%, according to 46brooklyn. Antonio Ciaccia, president of 3 Axis, said that drugmakers have focused on launching their drugs at higher prices because of the attention paid to annual price increases. More drug prices are likely to be announced over the course of January - historically the biggest month for drugmakers to raise prices. Sanofi plans to raise prices on 14 of its drugs or vaccines.

But persistent inflation and skimpier incomes, coupled with high input costs, will make it a tough year for conscious consumers and the companies that serve them. Take plant-based meat substitutes. They produce 30%-90% fewer emissions than their animal-derived counterparts, but a pound of the stuff costs shoppers twice as much, according to the Good Food Institute, a think tank. The price of U.S. pea protein isolate – a key ingredient in many meat substitutes – rose 10% between April 2021 and November 2022, according to Mintec Benchmark Prices. That would edge meat substitutes closer to their goal of one day costing the same, or less, than their animal-based equivalents.

Here are 12 of the weirdest and most fascinating animal behaviors scientists spotted in 2022. Here are 12 bizarre and amazing things animals were spotted doing, some of which had never been seen before. It turned out that at least 12 species of primates had been reported doing so, a review published in the Journal of Zoology in October found. A dolphin swallowed 8 venomous sea snakesA sea snake (indicated with pink arrow), moments before it is captured and eaten by a Navy dolphin. Though animals have often been spotted using tools, these usually are used to give the animal a clear survival advantage.

☆ Britain's charity stores are going upmarket
▼ + stars: | 2022-12-26 | by ( Grace Dean | ) www.businessinsider.com time to read: +13 min

Britain's charity shops are transforming as they try to appeal to Gen Z customers. The managers told Insider their retro and vintage stores were largely in urban areas with large student populations. Grace Dean/InsiderE-commerce for charity shops is completely different than e-commerce for retailers that sell large batches of new products. Nonessential retail stores had to shut their doors for months during the pandemic, which the Charity Retail Association estimated cost UK charity shops about £28 million, or $32 million, a month. But, as the aisles of charity shops across the UK show, a lot of people do choose to donate them.

☆ 'There's no place like home': Ukraine's refugees face their first Christmas away
▼ + stars: | 2022-12-22 | by ( Karen Gilchrist | ) www.cnbc.com time to read: +7 min

Ukrainian refugees near 8 millionPrylutska is one of more than 7.8 million Ukrainians — around one-fifth of the population — who have fled the country for Europe since Russia's invasion. I work with refugees, and I continue to do my work, but I am now a refugee, too. Kateryna Shukh, center, says she has found solace in supporting other Ukrainian refugees by hosting art therapy sessions from her new home in Warsaw, Poland. Kateryna ShukhIn Poland, for example, Ukrainian refugees have the legal right to remain for 18 months, with the possibility of applying for a three-year temporary residence permit. "Maybe 20% have gone back (to Ukraine) already," Shukh said of the refugees she works with.

☆ Conservationists move to permanently protect areas around proposed Alaskan mine
▼ + stars: | 2022-12-22 | by ( ) www.reuters.com time to read: +2 min

Dec 22 (Reuters) - The United States' top environmental non-profit and a regional land trust have raised $20 million to permanently protect 44,000 acres at an Alaskan watershed, that could be another major roadblock for a controversial proposed mine. The proposed Pebble Mine, being developed by a unit of Canada-based Northern Dynasty Minerals Ltd (NDM.TO), has been through a roller coaster of regulations for the past 15 years. "Notably, this effort will restrict development of an access road critical for the proposed Pebble Mine," said the Fund's spokesperson, Valerie Keefer. read moreThe fundraiser counted Patagonia's Holdfast Collective among its donors, along with The Wyss Foundation and Alaska Venture Fund. Reporting by Sourasis Bose, Ruhi Soni and Arshreet Singh in Bengaluru; Editing by Shailesh KuberOur Standards: The Thomson Reuters Trust Principles.

Mike Hodges, the British filmmaker who directed the hard-boiled gangster saga "Get Carter" and the campy space opera "Flash Gordon," died Saturday, according to his friend Mike Kaplan. "My middle-class eyes were forced to witness horrendous poverty and deprivation that I was previously unaware of," Hodges wrote in a letter published in The Guardian in May. "Get Carter" quickly entered the pantheon of British film classics. He replaced the acclaimed British director Nicolas Roeg ("Walkabout") on "Flash Gordon," a goofy project that has since attracted a cult following. I think that as a young man I probably did."

☆ Big Pharma will find right formula for M&A binge
▼ + stars: | 2022-12-20 | by ( Aimee Donnellan | ) www.reuters.com time to read: +3 min

The year 2022 was relatively thin for pharma M&A, with deals worth nearly $66 billion being announced by early December – 60% below the 9-year average, according to Refinitiv data; 2023 will be better. It helps that drug companies are relatively healthy, with debt around just 1.6 times forecast EBITDA in 2023, according to Berenberg analysts. Seagen (SGEN.O), for example, worth $22 billion in early December, has fought off Merck & Co (MRK.N). That puts Big Pharma in an ideal negotiating position. CONTEXT NEWSGlobal pharmaceutical companies spent nearly $66 billion on takeovers in 2022, according to data from Refinitiv as of Dec. 7.

☆ A tiny biotech's experimental treatment for a silent disease that strikes millions just cleared a key hurdle and the stock is up more than 200%
▼ + stars: | 2022-12-19 | by ( Sarah Braner | ) www.businessinsider.com time to read: +2 min

Madrigal Pharmaceuticals reported positive results in its phase 3 trial for a drug to treat NASH. NASH is a serious liver condition that does not have an FDA-approved treatment. Many people don't even know they have it, which is why some people call it a "silent" disease. In a trial of more than 950 patients, 26% of patients taking 80mg and 30% of patients taking 100mg of the drug showed that NASH activity like swelling had been reduced. Pharma hasn't found a way to treat NASH yetThe pharma industry has been watching NASH for a while.

☆ Fact Check-New ‘Er’ blood group is not proof COVID-19 vaccines alter DNA
▼ + stars: | 2022-12-16 | by ( Reuters Fact Check | ) www.reuters.com time to read: +3 min

A recently discovered blood group system called Er is not proof that mRNA in COVID-19 vaccines is changing people’s DNA, as some social media users have claimed. Scientists told Reuters that Er has always existed and antigens from the blood group were first discovered more than 40 years ago. New blood group systems have been regularly discovered for decades.”Bailey said: “One of the antigens that make up the blood group system was discovered more than 40 years ago. The existence of the blood group Er does not suggest that mRNA vaccines are changing people’s blood types or DNA. Antigens from the blood group Er were first discovered 40 years ago.

☆ British nurses launch historic strike, as pay and staffing crises threaten the NHS
▼ + stars: | 2022-12-15 | by ( Rob Picheta | ) edition.cnn.com time to read: +9 min

“The reality is, every day, nurses across the UK are walking into understaffed hospitals,” Mackay said. “I feel really sorry for the young girls who are now trying to get into the profession, they have to pay for their training. Nurses’ pay dropped 1.2% every year between 2010 and 2017 once inflation was taken into account, according to the Health Foundation, a UK charity that campaigns for better health and health care. Christopher Furlong/Getty ImagesEarlier this year, the RCN rejected an offer by the government to increase nurses’ pay by a minimum of £1,400 ($1,707) a year, which amounted to an average rise of 4.3%, well below the rate of inflation. Members of Britain’s armed forces were being trained to drive ambulances and firefight in the event of strike action, ministers said earlier this month.

☆ Man kills his fiancée’s father and shoots her mother and sister after demanding they move out
▼ + stars: | 2022-12-07 | by ( Marlene Lenthang | Marlene Lenthang Is A Breaking News Reporter For Nbc News Digital. | ) www.nbcnews.com time to read: +2 min

A Massachusetts man fatally shot his fiancée's father and wounded her mother and sister, then turned the gun on himself, after expressing he was “unhappy” that they were living with him, prosecutors said. His fiancée’s sister, 25, and their mother, 59, were also hospitalized at St. Luke’s Hospital in New Bedford and are both expected to survive. Shortly after, Labasquin got into a physical struggle with Baptiste, “at which point Mr. Labasquin was shot,” the district attorney’s office said. As the fiancée was calling 911, Baptiste allegedly shot her mother and sister then shot himself, prosecutors said. He had a valid license to carry the firearm, according to the district attorney’s Office.

☆ Chattermill helps Amazon and Uber understand customer feedback across social media and review sites. Check out the 14-slide pitch deck it used to raise a $26 million Series B.
▼ + stars: | 2022-12-06 | by ( Tasmin Lockwood | ) www.businessinsider.com time to read: +5 min

London-based Chattermill has raised $26 million to analyze customer feedback for big firms. Isupov had been working at a market research company, manually looking at customer feedback and brand perception. That essentially is a huge waste of opportunity because there is a lot of amazing insight in that data," Dubov added. As well as scraping internet data, Chattermill plugs into SurveyMonkey, Typeform, and Qualtrics. It is honoring some signed contracts with Russian customers, of which none are Kremlin-affiliated or on a sanctions list, Dubov said.

☆ What to watch for as J&J gets ready to split into two separate companies next year
▼ + stars: | 2022-12-06 | by ( Paulina Likos | ) www.cnbc.com time to read: +11 min

During Monday's "Morning Meeting" for members, Jim Cramer said that J & J has the "best balance sheet in America." According to projections from J & J and rival Medtronic (MDT), the robotics market captures a low 2% to 3% of global procedures. In an economic slowdown, J & J is a solid name to own that can outperform the broader market. We also like that J & J has consistently raised its dividend. We rate J & J a 1 for the Club , meaning we would buy the stock at current levels given it aligns with our strategy.

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☆ Ex-trooper bought home, blacked out windows, weeks before allegedly killing family of teen he catfished, seller says
▼ + stars: | 2022-12-03 | by ( Tim Stelloh | Tim Stelloh Is A Breaking News Reporter For Nbc News Digital. | ) www.nbcnews.com time to read: +4 min

Property records from Smyth County, Virginia, list Austin Lee Edwards as the owner of the home on Allison Gap Road. “It still doesn’t feel real," Gordon told NBC affiliate WCYB of Bristol, Virginia. A fire that authorities believe was intentionally set broke out at their home and Edwards allegedly drove off with the teen. Gordon said Edwards told him that he moved to the area because he'd grown up in the region and wanted to return. The last time Gordon said he saw Edwards was Tuesday, Nov. 22, three days before the Wineks were killed.

☆ Brexit has added 6% to Britons' food bills, new study finds
▼ + stars: | 2022-12-01 | by ( Karen Gilchrist | ) www.cnbc.com time to read: +3 min

Brexit has added more than £200 to the average U.K. household food bill, according to a new study from the London School of Economics. In all, U.K. consumers paid £5.8 billion ($7 billion) in additional grocery costs over the two years, the study found. Over the two years to the end of 2021, Brexit increased food prices by around six per cent overall," Davies added. The report also found that while domestic U.K. food producers have benefited from less competition, their gains were outstripped by consumer losses to the tune of over £1 billion. EU food exporters and U.K. food importers have transferred 50% to 88% of post-Brexit costs onto consumers, according to research.

☆ Ericsson to invest in 6G network research in Britain
▼ + stars: | 2022-11-22 | by ( ) www.reuters.com time to read: +1 min

LONDON, Nov 22 (Reuters) - Network equipment maker Ericsson (ERICb.ST) will invest millions of pounds in 6G mobile research in Britain, it said on Tuesday, working with universities on hardware security, AI and cognitive networks and quantum computing. The Swedish company, which supplies 5G gear to all four British mobile networks, said the 10-year initiative would help to drive development of next-generation 6G networks, which are expected to be commercially available about 2030. Ericsson's UK and Ireland CEO Katherine Ainley said that British universities are performing world-beating research in some of the technologies that would underpin next-generation networks. The new group will complement Ericsson's 17 existing research sites in 12 countries, she said. Reporting by Paul Sandle Editing by Kylie MacLellan and David GoodmanOur Standards: The Thomson Reuters Trust Principles.

One of the biggest makers of generic drugs, Israeli-based Teva said it aims eventually to secure a 10% global market share of biosimilars. A division of Novartis (NOVN.S), Sandoz is currently the second biggest player after Pfizer Inc (PFE.N) in the biosimilar market by gross sales globally, per IQVIA data, cited by Sandoz. Sandoz launched eight biosimilar drugs between 2017 and 2021, including a version of Bristol-Myers’ multiple myeloma drug Revlimid. The analysis projected the value of the global biosimilar market could more than triple to an estimated $74 billion by 2030. Sandoz and Teva are both working on biosimilars for Humira.

☆ Final Trades: Southwest Gas, Bristol-Myers, Albemarle & more
▼ + stars: | 2022-11-21 | by ( ) www.cnbc.com time to read: 1 min

In this videoShare Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailFinal Trades: Southwest Gas, Bristol-Myers, Albemarle & moreThe "Halftime Report" traders give their top picks to watch for the second half.

☆ This 31-year-old CEO says staying focused on one disease was the key to helping his company raise $120 million in a frozen biotech market
▼ + stars: | 2022-11-18 | by ( Yeji Jesse Lee | ) www.businessinsider.com time to read: +6 min

Arthur Kuan is the 31-year-old CEO of CG Oncology, a startup focused on treating bladder cancer. CG announced earlier this week that it has raised $120 million, despite a difficult biotech market. Since 2016, the year that Kuan became the CEO of CG Oncology, the Irvine, California-based cancer startup has raised big rounds from investors. "I think I've seen a lot of successful stories where you've stayed very focused on just one thing and you just see things that others don't by being very deep," Kuan told Insider. But when his father died that same year from pancreatic cancer, Kuan said he decided to focus on bladder cancer.

☆ Ghana name uncapped pair who have impressed in Europe
▼ + stars: | 2022-11-14 | by ( ) www.reuters.com time to read: +2 min

Nov 14 (Reuters) - Kamal Sowah’s form for Club Brugge in the Champions League has won him a World Cup call-up for Ghana after the uncapped striker was on Monday included in the country’s squad for Qatar. The 22-year-old was a surprise selection as coach Otto Addo named his 26-man squad for the tournament, where the Black Stars face Portugal, South Korea and Uruguay in Group H.Sowah has impressed as the Belgian club reached the last 16 of the Champions League, knocking out Atletico Madrid and Bayer Leverkusen in the process. There was also a first call up for midfielder Salis Abdul Samed, 22, who has been a regular for Racing Lens this season as they have moved to second in the French Ligue 1 standings. The squad will be captained by Dede Ayew, who was part of the team that reached the quarter-finals in South Africa in 2010 – only the third time an African nation has reached the last eight of a World Cup. Writing by Mark Gleeson in Cape Town; Editing by Ed OsmondOur Standards: The Thomson Reuters Trust Principles.

In the three years to the end of 2021, Alphabet, Meta and Snap (SNAP.N) hared ahead. The upshot was the Big Tech groups boasted 2021 revenue of $380 billion, most of which was digital advertising. Alphabet, Meta and Snap saw revenue up a miserly 2.4%, on average. For one thing, digital ad giants’ stellar 2021 made maintaining the pace trickier. Meta and Alphabet will still see some of this cash given traditional ad players will use platforms like Google for these big clients’ digital advertising.

☆ Fertilizers change how bumblebees 'see' flowers by changing the electric field that attracts them to pollinate, study finds
▼ + stars: | 2022-11-09 | by ( Marianne Guenot | ) www.businessinsider.com time to read: +4 min

A study found fertilizers change that electric field and put bumblebees off from fertilizing. When they came across negatively-charged flowers, their small bodies sense the flower's electric field like a magnet. When they pollinate, the bees change the flowers' electric field. Ed Reschke/Getty imagesFertilizers change the electric fieldThe study found that spraying synthetic fertilizers onto a field didn't change the color or smell of the flower. To test whether the sprayed flower's electric field was putting off the bees, the scientists artificially charged flowers to mimic these electric fields.

☆ Final Trades: PayPal, Merck, Bristol Myers & more
▼ + stars: | 2022-11-09 | by ( ) www.cnbc.com time to read: 1 min

In this videoShare Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailFinal Trades: PayPal, Merck, Bristol Myers & moreThe "Halftime Report" traders give their top picks to watch for the second half.

☆ Kaedim's founder doesn't play video games — but her startup's use of AI to develop graphics has caught the attention of the former head of PlayStation
▼ + stars: | 2022-11-08 | by ( Jacob E. Robbins | ) www.businessinsider.com time to read: +3 min

"I thought there has to be a secret to doing 3D modeling. She asked game developers how they would approach 3D modeling, thinking they'd have an answer from their experience rendering objects on a screen. It uses machine learning to turn drawings into digital 3D models. Kaedim's plan to take on 3D modeling in the metaverse and digital businessPsoma said that with the rise of the metaverse and digital spaces, the need for 3D modeling has only grown. For example, she said, retailers could use Kaedim's 3D-modeling software to digitize inventory and create online storefronts for customers to interact with.

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