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Eli Lilly’s golden ticket is a regrettable winner
  + stars: | 2023-05-03 | by ( Robert Cyran | ) www.reuters.com   time to read: +6 min
NEW YORK, May 3 (Reuters Breakingviews) - Eli Lilly’s (LLY.N) Mounjaro might turn out to be the biggest selling drug ever. The pharmaceutical giant is maximizing the diabetes treatment’s gain by using a golden ticket to speed its U.S. approval for use in a possibly bigger market, obesity. Lilly’s peak sales for treating obesity might be about 10 times as high, Jefferies analysts estimate. At the industry multiple of 5 times revenue, that would pad its $535 billion market value by $30 billion. Lilly may have secured a Willy Wonka-like golden ticket that allows its obesity drug to reach customers quicker.
I once took an orphaned deer mouse to a nearby wildlife rehabilitator, and she cautiously introduced it to a nursing house mouse who was also in her care. The mouse accepted the baby stranger of another species and raised it as her own. Even in the wild, there are documented instances of what appears to be interspecies adoption — a killer whale raising a pilot whale calf, a southern right whale raising a baby humpback, a lioness raising a leopard cub. Plus, RockBaby wasn’t gaping for food or crying for help in that impossible-to-ignore way of needy babies everywhere. RockBaby wasn’t even animate.
Some companies, including Exxon Mobil Corp (XOM.N), have been dumping assets in the Gulf, the nation's primary offshore source of oil, and are instead targeting capturing and storing carbon dioxide and other greenhouse gases underground. The region, soon could became contested ground for oil, carbon sequestration and renewable energy, say analysts. The gain reflects a flurry of new platforms from Shell (SHEL.L), BP (BP.L), Chevron (CVX.N) and others, budgeted before the pandemic hit global demand and made companies reduce investments. Reuters GraphicsAt this week's Offshore Technology Conference (OTC), which annually attracts more than 50,000 people, nearly a quarter of the presentations will involve offshore wind, renewables, carbon capture and energy transition, say organizers. Oil development will still dominate the basin, but should coexist with CCS and renewables such as offshore wind and solar.
The findings in the ambitious Zoonomia Project identified parts of the genome functionally important in people and other mammals and showed how certain mutations can cause disease. The project revealed the genetics of uncommon mammalian traits like hibernation and showed how the sense of smell varies widely. The researchers said the findings on hibernation genetics could inform human therapeutics, critical care and long-distance space flight. The most primitive species was the venomous burrowing insect-eater Hispaniola solenodon, closely related to mammals alive during the dinosaur age. In terms of human differences from other mammals, the study pointed to regions associated with developmental and neurological genes.
What’s sometimes lost in this feast for the eyes is the sonic world of animals — audible to humans in the case of birdsong. Source: British Library“Animals: Art, Science and Sound” showcases the British Library’s wildlife collection, which contains over 250,000 recordings of animals from around the world. Source: British LibraryThe species was declared extinct in 2000. The song of a nightingale Published by the Gramophone Company Ltd. in 1910, it was the first published recording of any animal. Source: British LibraryThe groundbreaking release marked the beginning of commercial wildlife recording that culminated in the 1970s.
Inside Qatar’s ‘city of the future’
  + stars: | 2023-04-24 | by ( Ulrike Lemmin-Woolfrey | ) edition.cnn.com   time to read: +8 min
Like others, it has moved from the capital Doha to this, Qatar’s newest city – 10 miles north. Andrej Isakovic/AFP/Getty ImagesLusail claims to be Qatar’s first sustainable city – no easy task for a newbuild in the desert. There’s an extensive choice from food trucks at the Lusail Marina Food Arena, abundant cafes, and fine dining restaurants.”A sprawling city of the futureThe Marina area is fast proving a hit for residents. Al Tara – the district, by Al Maha Island, where Warner lives – is home to the Lusail Marina. There is a rumor – as yet unsubstantiated – that Lusail might eventually become Qatar’s capital city.
"I never saw myself as a speaker, let alone a motivational speaker," Leonard tells me while his assistant irons his jeans. 'When I ramble," Hunter told me, "hit me in the leg!" Every plane had been grounded, including the one stuck on the tarmac with an increasingly inebriated Hunter Thompson trapped inside. But by far the most all-consuming task was booking gigs for Hunter Thompson. Just before a debate with G. Gordon Liddy at Brown University, Hunter demanded that Betsy Berg, whom I now worked alongside at GTN, score him some crystal meth.
CNN —When Sharon Lane heard about a cruise company offering a three-year-long voyage around the world, she immediately started fantasizing about life on board. While it’s long been Lane’s dream to live on a cruise ship full time, the steep cost has always been a barrier. I don’t know, the sky’s the limit.”Preparing for a new lifeSharon Lane will spend three years living on the MV Gemini cruise ship, pictured here. The 130-square-feet cabin has no window, but guests have been promised a screen that will broadcast live footage from outside the ship. Lane won’t disembark the ship in certain destinations, like Antarctica, where the cold air might aggravate her lungs.
For 2023, it’s been given the title as a Cultural Capital of Europe – a title it shares with Timisoara in Romania and Veszprem in Hungary. Sergio Tsitakis / Design Farm ProductionsFor the occasion, the city’s magnificent archaeological site has been overhauled, improving its accessibility. Being a Cultural Capital has helped dozens of cities that have previously held the title to foster urban regeneration and find a spot on the travel radar. Among upcoming highlights this summer is a play, “Ma,” by Italian director and playwright Romeo Castellucci, a performance specially created to be staged in Eleusis’ archaeological site. And with the majority of international flights landing in Athens, Eleusis is perfectly located as an easy-to-reach destination.
Solar eclipse tourism in Exmouth, Western Australia
  + stars: | 2023-04-20 | by ( Lilit Marcus | ) edition.cnn.com   time to read: +3 min
CNN —Thursday’s hybrid solar eclipse will last for 62 seconds. That’s the hope for Exmouth and the surrounding Ningaloo Coast in Western Australia, which are hoping that April 20th’s once-in-a-decade natural phenomenon could kick off a tourism boom that lasts well beyond the eclipse. “They’re pretty intimidated but also very excited,” Roger Cook, Deputy Premier of Western Australia state, tells CNN about the residents of Exmouth. And there’s some evidence of the region’s growing prominence on the international stage: CNN Travel selected Western Australia for our list of the best places to visit in 2023. Altogether, Western Australia state spent 20 million AUD ($13.5 million) on infrastructure updates for the eclipse, which included everything from water and sanitation services to additional parking.
Sharrow Marine sells them for small boats but would need to scale up to reach the shipping industry. A traditional ship propeller that has blades in a screw-like form. That's what Sebastian realized when he put loop propellers on a drone. Sharrow began selling propellers to recreational boaters in 2020 through a company he founded called Sharrow Marine. Testing led by the company BoatTEST found that the Sharrow Propeller was up to 30% more efficient than a standard blade propeller.
By-the-wind sailors are beginning to wash up onto shores in California. Beaches from Dana Point to Point Reyes National Seashore have seen the creatures on their shores. Known by the scientific name Velella velella, the hydrozoa is actually a collection of polyps that float through the ocean using a translucent "sail" that sits upright on a flat, oval body to catch the wind. In 2014 and 2015, a Velella bloom resulted in billions of by-the-wind sailors washed ashore beaches from California to Washington. Dana Wharf Whale Watching did not immediately respond to Insider's request for comment.
[1/3] A vending machine menu offering Asian Black Bear meat, Akita Beef and dried mountain stream fish is seen in front of a Soba Noodle restaurant in Semboku, Akita prefecture, Japan April 6, 2023. REUTERS/Irene WangSEMBOKU, Japan, April 6 (Reuters) - A remote Japanese town has taken to selling bear meat from a vending machine, sourcing its supply to Asian black bears, listed as a vulnerable species, caught in traps or in the mountains by hunters. Asian black bears are listed as vulnerable, but not critically so, and it is legal to eat bear in Japan. Vending machines throughout Japan offer everything from drinks, snacks and surgical masks to more exotic fare such as edible insects and whale meat. "Bear meat isn't very common so we want tourists who come to visit the town to buy it," Sato said.
Why, then, has Dimon been so willing to swing back into action in the wake of Silicon Valley Bank's collapse? But it's starting to look like JPMorgan — and Dimon — will end up winners no matter how things turn out. In backstopping First Republic, JPMorgan helps a client and a bank that experts say would fit nicely into its business. By saving First Republic, JPMorgan also stands to gain goodwill from Silicon Valley startups, which are customers of the smaller bank. The paper also reported that regulators asked Dimon, Bank of America, and other banks to buy Silicon Valley Bank and pay out depositors over the insured limit.
The High Seas Treaty, Explained
  + stars: | 2023-03-30 | by ( Haphazard Authority On Ocean Resources | ) www.reuters.com   time to read: +12 min
Global News Changing Tides The first international agreement to protect the world's oceans aims to create “international parks” in the high seas. The high seas represent 95% of the world’s total habitat by volume, but the nautical world remains largely unexplored. “A sentiment we often encountered was that there’s not much in terms of biodiversity out there in the high seas,” he said. MPAs that already exist mostly occupy exclusive economic zones and only make up about 3% of the high seas. A 2016 Pew study on mapping governance in the high seas showed 19 governing bodies with a high seas mandate.
[1/2] A killer whale jumps out of the water in the sea near Rausu, Hokkaido, Japan, July 1, 2019. REUTERS/Kim Kyung-HoonMarch 30 (Reuters) - A Florida aquarium has reached a deal with animal welfare advocates to release Lolita, a 5,000-pound (2,268 kg) killer whale held in captivity for more than half a century, officials said on Thursday. The plan to return Lolita to her natural habitat requires federal approval, according to the newspaper. The Seaquarium's previous owner, SeaWorld Entertainment Inc (SEAS.N), phased out killer whale shows in 2016. Killer whales are highly social mammals that have no natural predators and can up to 80 years.
[1/2] Boaz Weinstein, founder and chief investment officer at Saba Capital Management, speaks during the SALT conference in Las Vegas, Nevada, U.S. May 17, 2017. REUTERS/Richard BrianLONDON, March 20 (Reuters) - Hedge fund manager Boaz Weinstein pinned hopes on Credit Suisse's survival, but also money on its demise. At the time Weinstein told Reuters he thought the derivatives were mis-priced because he believed Credit Suisse's problems would be resolved, either way, more quickly. As the trade is both long and short, Weinstein stands to profit from the short leg of his trade much more than he will lose from the long side. Weinstein led a proprietary trading fund at Deutsche Bank which was spun out to start Saba Capital Management in 2009.
WASHINGTON, March 14 (Reuters) - The White House on Tuesday welcomed the "landmark" deal between Saudi Arabia and the Boeing Co (BA.N), saying it will support U.S. jobs and marked a milestone in cooperation between Saudi Arabia and American industry. Boeing Chief Executive Dave Calhoun said in an interview the planemaker got "support from the Biden administration and from key members of Congress every step of the way... The Biden Administration has done a terrific job in moving the ball forward and was instrumental in landing this purchase." A U.S. official said the Saudi contract was a "white whale" for Boeing, something the planemaker pursued for several years. Senior U.S. officials have been in regular engagement with the Saudis over the deal, but Biden did not have any direct talks with Saudi leaders.
Fossils dating to about 250 million years ago unearthed in a harsh and remote locale - Norway's Arctic island of Spitsbergen - are now providing surprising insight into the rise of ichthyosaurs. The fossils showed this one, which has not yet been given a scientific name, was quite advanced anatomically. The site where the fossils were found is a classic Arctic landscape with high snow-capped mountains along the coast of a deep fjord. The mass extinction shook up land and marine ecosystems and opened opportunities for new species to fill ecological roles vacated by extinct creatures. Fossils show ichthyosaurs giving live birth to their young.
LOS ANGELES, March 13 (Reuters) - Independent studio A24 was the big winner at Sunday's Academy Awards, taking nine awards out of its 18 nominations, including best picture and all four acting prizes. The studio's "Everything Everywhere All at Once" won seven Oscars, the most of the evening, including best picture. However, Brendan Fraser took the best actor prize for A24's "The Whale," which also won for best makeup and hairstyling. Not since the heyday of Miramax in the 1990s has an independent studio garnered such attention, talent and box office success, entertainment industry insiders say. EVERYTHING EVERYWHEREThe first film A24 produced and financed, together with Brad Pitt’s Plan B Entertainment, was “Moonlight,” which won the Oscar for best picture in 2017.
Brendan Fraser wins best actor Oscar for ‘The Whale’
  + stars: | 2023-03-13 | by ( ) www.reuters.com   time to read: +2 min
The film was adapted from Samuel Hunter's 2012 play of the same name. The role marked his return to the big screen as a leading man after a nine-year absence from major roles. The film drew criticism from some reviewers who said its depiction of Charlie relied on tropes of depressed, obese people. Some spoke out against its use of prosthetics rather than casting an obese actor. (Writing by Ben Kellerman; editing by Jonathan Oatis)((benjamin.kellerman@thomsonreuters.com))Keywords: AWARDS OSCARS/ACTOROur Standards: The Thomson Reuters Trust Principles.
LOS ANGELES, March 12 (Reuters) - Independent film studio A24 emerged as the big winner at Oscar night on Sunday, sweeping every major category, propelled by the quirky, reality-bending film "Everything Everywhere All at Once" and the drama "The Whale." The studio claimed a total of nine Academy Awards, with "Everything Everywhere All at Once" receiving seven Oscars, including for best picture, director, actress, original screenplay and supporting actor and actress. Disney's leading Oscar contender, "The Banshees of Inisherin," received multiple nominations, but no awards. CNN celebrated its first Oscar win for "Navalny," a portrait of Russian opposition leader Alexei Navalny, which won best documentary feature film. NBCUniversal collected 15 nominations, led by Universal Picture’s "The Fabelmans," directed by Steven Spielberg, and six for "Tar" from Focus Features, but no Oscars.
Factbox: Full list of winners at the 2023 Oscars
  + stars: | 2023-03-13 | by ( ) www.reuters.com   time to read: +1 min
LOS ANGELES, March 13 (Reuters) - The 95th Academy Awards took place at a ceremony in Los Angeles on Sunday and were broadcast live on ABC television. The following is the full list of 2023 Oscar winners:BEST PICTURE"Everything Everywhere All at Once"BEST ACTRESSMichelle Yeoh, “Everything Everywhere All at Once"BEST ACTORBrendan Fraser, "The Whale"BEST DIRECTORDaniel Kwan and Daniel Scheinert, "Everything Everywhere All at Once"BEST SUPPORTING ACTORKe Huy Quan, "Everything Everywhere All at Once"BEST SUPPORTING ACTRESSJamie Lee Curtis, "Everything Everywhere All at Once"BEST INTERNATIONAL FEATURE FILM"All Quiet on the Western Front," GermanyBEST ANIMATED FEATURE FILM"Guillermo del Toro's Pinocchio"BEST DOCUMENTARY FEATURE FILM"Navalny"BEST ORIGINAL SCREENPLAY"Everything Everywhere All at Once," written by Daniel Kwan and Daniel ScheinertBEST ADAPTED SCREENPLAY"Women Talking," screenplay by Sarah PolleyBEST ORIGINAL SCORE"All Quiet on the Western Front," Volker BertelmannBEST ORIGINAL SONG"Naatu Naatu," from "RRR," music by M.M. Keeravaani; lyrics by ChandraboseCINEMATOGRAPHY"All Quiet On The Western Front," James FriendVISUAL EFFECTS"Avatar: The Way of Water"SOUND"Top Gun: Maverick"FILM EDITING"Everything Everywhere All at Once"PRODUCTION DESIGN"All Quiet On The Western Front"COSTUME DESIGN"Black Panther: Wakanda Forever," Ruth CarterMAKEUP AND HAIRSTYLING"The Whale"DOCUMENTARY SHORT FILM"The Elephant Whisperers"SHORT FILM, LIVE ACTION"An Irish Goodbye"SHORT FILM, ANIMATED"The Boy, the Mole, the Fox and the Horse"Reporting by Mary Milliken; editing by Jonathan OatisOur Standards: The Thomson Reuters Trust Principles.
The bond market's recession warning has gotten more urgent
  + stars: | 2023-03-13 | by ( Patti Domm | In | ) www.cnbc.com   time to read: +5 min
The bond market is sending a more urgent recession warning and also signaling that the Federal Reserve may have to pause raising interest rates — giving up its fight against inflation. The sharp move in the 2-year yield also resulted in a rapid steepening of the yield curve. "The steepening always starts to happen because the market expects the Fed to cut rates in response to that recession." DoubleLine Capital CEO Jeffrey Gundlach also said the "aggressively steepening" of the Treasury yield curve after inversion is "highly suggestive of imminent recession." The 2-year yield jumped above 5% after he spoke.
In case of an unexpected twist, a crisis response team will be on hand at the Dolby Theatre in Los Angeles. Several of 2022's biggest hits at the multiplex landed in the best picture race, from "Top Gun" and "Everything Everywhere" to "Elvis" and "Avatar: The Way of Water." To change up the look, organizers swapped out the traditional red carpet for the first time since 1961, opting instead for a champagne color. "Everything Everywhere All at Once," an offbeat story about a Chinese-American laundromat owner struggling to finish her taxes, comes in as the favorite to win best picture. The dimension-hopping kung fu adventure has swept the major Hollywood awards in the weeks leading up to the Oscars.
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